Title: Basilica of Santi Cosma e Damiano in Rome City Centre | Expedia.co.uk [Basilica of Santi Cosma e Damiano Hotels](https://expedia.co.uk/Basilica-Of-Santi-Cosma-E-Damiano-Hotels.0-l553248621533001950-0.Travel-Guide-Filter-Hotels)[Basilica of Santi Cosma e Damiano Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Basilica-Of-Santi-Cosma-E-Damiano.d553248621533001950.Car-Hire-Guide)[Rome City Centre Holidays](https://expedia.co.uk/Rome-City-Centre.d553248633938945217.Holidays-City-Breaks) # Basilica of Santi Cosma e Damiano ![Lazio showing signage](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/99000/99765-Basilica-Dei-Santi-Cosma-E-Damiano.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Lazio](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/99000/99766-Basilica-Dei-Santi-Cosma-E-Damiano.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Basilica of Santi Cosma e Damiano Activities --- --- ## Plan a trip to see Basilica of Santi Cosma e Damiano Price found within the past 48 hours. Click for updated prices. ![Albergo Etico Roma](https://images.trvl-media.com/lodging/34000000/33130000/33120500/33120475/6b9ee00e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Albergo Etico Roma Flaminio £152 per person 11 Jan - 14 Jan found 1 day ago Return flight included Birmingham (BHX) to Rome (FCO) 9.6/10 Exceptional! (335 reviews) Great place to stay Reviewed on 1 Dec 2025 ![Relais de la Poste](https://images.trvl-media.com/lodging/39000000/38910000/38902300/38902220/aa8b51a2_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Relais de la Poste Rome City Centre £182 per person 11 Jan - 14 Jan found 1 day ago Return flight included Birmingham (BHX) to Rome (FCO) 9.2/10 Wonderful! (612 reviews) Clean room friendly staff Reviewed on 12 Dec 2025 ![Charme Spagna Boutique Hotel](https://images.trvl-media.com/lodging/19000000/18300000/18294700/18294667/57c4458b_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Charme Spagna Boutique Hotel Rome City Centre £321 per person 25 Feb - 1 Mar found 4 hours ago Return flight included London (LTN) to Rome (FCO) 9.2/10 Wonderful! (208 reviews) The staff was so lovely and polite and really helpful, hotel was clean and everything you needed. Hotel was brilliant location, only thing I would say is taxis and Ubers are a lot cheaper than the transfer service to airport that the hotel offered, but would defo recommend Reviewed on 4 Dec 2025 ### Tours & day trips [See all 405 activities](https://expedia.co.uk/things-to-do/search?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&filter.categories=ToursDayTrips) ![Vatican Museums, Sistine Chapel, & St. Peter’s Basilica Fully Guided Tour](https://mediaim.expedia.com/localexpert/166597/4f9bb377-01c6-4b8f-980f-7747e7f07a85.jpg?impolicy=resizecrop&rw=500&rh=280) ### Vatican Museums, Sistine Chapel, & St. Peter’s Basilica Fully Guided Tour 3h 9/10 6,549 reviews Free cancellation available £69 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/vatican-museums-sistine-chapel-st-peters-basilica-fully-guided-tour.a166597.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Colosseum & Ancient Rome Guided Tour with Roman Forum & Palatine Hill](https://mediaim.expedia.com/localexpert/166587/4edbea50-914d-4144-a851-55e98d3e0a1f.jpg?impolicy=resizecrop&rw=500&rh=280) ### Colosseum & Ancient Rome Guided Tour with Roman Forum & Palatine Hill 3h 9.2/10 3,904 reviews Free cancellation available £43 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/colosseum-ancient-rome-guided-tour-with-roman-forum-palatine-hill.a166587.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour](https://mediaim.expedia.com/localexpert/3138351/99f75742-d99d-48ce-8246-922f96cce825.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour 2h 30m 8.4/10 256 reviews Free cancellation available £26 includes taxes & fees per adult\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.co.uk/things-to-do/rome-colosseum-with-arena-roman-forum-and-palatine-guided-tour.a3138351.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Pompeii, Amalfi Coast and Positano Day Trip from Rome](https://mediaim.expedia.com/localexpert/442250/aa41f01e-adac-4892-9511-7475ae5b39d6.jpg?impolicy=resizecrop&rw=500&rh=280) ### Pompeii, Amalfi Coast and Positano Day Trip from Rome 13h 9.2/10 460 reviews Free cancellation available £74 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/pompeii-amalfi-coast-and-positano-day-trip-from-rome.a442250.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![From Rome: Tuscany & Montepulciano Day Trip including Lunch & Wine Tasting](https://mediaim.expedia.com/localexpert/166552/04a98a7b-1b9b-4323-933f-1da13e16b5ee.jpg?impolicy=resizecrop&rw=500&rh=280) ### From Rome: Tuscany & Montepulciano Day Trip including Lunch & Wine Tasting 11h 9.6/10 968 reviews Free cancellation available £65 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/from-rome-tuscany-montepulciano-day-trip-including-lunch-wine-tasting.a166552.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![From Rome: Sorrento & Amalfi Coast with Pompeii or Positano Option](https://mediaim.expedia.com/localexpert/238327/66f41112-0db2-4e77-9ec7-cb838b38abe8.jpg?impolicy=resizecrop&rw=500&rh=280) ### From Rome: Sorrento & Amalfi Coast with Pompeii or Positano Option 12h 9.2/10 110 reviews Free cancellation available £60 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/pompeii-amalfi-coast-and-sorrento-day-trip-from-rome.a238327.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Gems of Tuscany: Florence & Pisa One Day Excursion from Rome](https://mediaim.expedia.com/localexpert/2461139/37393bb8-a798-4b51-a70b-513eb050f654.jpg?impolicy=resizecrop&rw=500&rh=280) ### Gems of Tuscany: Florence & Pisa One Day Excursion from Rome 14h 8.8/10 61 reviews Free cancellation available ~~£131~~£65 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/gems-of-tuscany-florence-pisa-1-day-excursion-from-rome.a2461139.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Trevi Fountain Undergound Domus Guided Tour](https://mediaim.expedia.com/localexpert/49601875/96a70552-3681-4cd4-9960-896373b17894.jpg?impolicy=resizecrop&rw=500&rh=280) ### Trevi Fountain Undergound Domus Guided Tour 1h+ 9.4/10 23 reviews Free cancellation available £33 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/trevi-fountain-undergound-domus-guided-tour.a49601875.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Colosseum Underground & Ancient Rome Guided Tour](https://mediaim.expedia.com/localexpert/3087492/c7df9e4a-f554-401b-b44f-9b6b8cfbc8c5.jpg?impolicy=resizecrop&rw=500&rh=280) ### Colosseum Underground & Ancient Rome Guided Tour 3h 9.4/10 28 reviews £46 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/the-vip-colosseum-underground-ancie.a3087492.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ### Private & custom tours [See all 82 activities](https://expedia.co.uk/things-to-do/search?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&filter.categories=Privatecustomtours) ![3-Hour Private Tour of Rome with Golf Cart](https://mediaim.expedia.com/localexpert/48493743/c91d173f-8133-406b-903a-ff44930c05ff.jpg?impolicy=resizecrop&rw=500&rh=280) ### 3-Hour Private Tour of Rome with Golf Cart 4h 10/10 4 reviews Free cancellation available £162 includes taxes & fees per adult\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.co.uk/things-to-do/3-hour-private-tour-of-rome-with-golf-cart.a48493743.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Skip-the-Line Vatican, Sistine Chapel Semi-Private Tour](https://mediaim.expedia.com/localexpert/510394/0f88bc01-d5af-4cd9-b641-05324785210f.jpg?impolicy=resizecrop&rw=500&rh=280) ### Skip-the-Line Vatican, Sistine Chapel Semi-Private Tour 3h 7.8/10 6 reviews Free cancellation available ~~£227~~£127 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/skip-the-line-vatican-sistine-chapel-semi-private-tour.a510394.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Fiat 500 Vintage Car Tour in Rome with Professional Photographer](https://mediaim.expedia.com/localexpert/49942107/1bf7d0f6-fc82-426a-a26c-7b7fbb1160df.jpg?impolicy=resizecrop&rw=500&rh=280) ### Fiat 500 Vintage Car Tour in Rome with Professional Photographer 1h 30m Free cancellation available ~~£75~~£60 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/fiat-500-vintage-car-tour-in-rome-with-professional-photographer.a49942107.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Explore the Best Highlights of Rome by Golf Car - Private Tour](https://mediaim.expedia.com/localexpert/44949953/34eea4bd-6af8-42f9-9cf2-b5d55a756401.jpg?impolicy=resizecrop&rw=500&rh=280) ### Explore the Best Highlights of Rome by Golf Car - Private Tour 2h 30m 9.8/10 7 reviews Free cancellation available £60 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/explore-the-best-highlights-of-rome-by-golf-car-private-tour.a44949953.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Colosseum Arena Floor & Ancient Rome Semi Private Max 6 People](https://mediaim.expedia.com/localexpert/483840/35830ea5-5b4f-47fa-861a-b9cfcb8ecaa1.jpg?impolicy=resizecrop&rw=500&rh=280) ### Colosseum Arena Floor & Ancient Rome Semi Private Max 6 People 3h 9.6/10 5 reviews Free cancellation available £166 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/colosseum-arena-floor-ancient-rome-semi-private-max-6-people.a483840.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Horse Sanctuary & Trail Ride](https://mediaim.expedia.com/localexpert/1146828/c40f4d5d-dc3c-4515-9e10-bc97cb1a8c82.jpg?impolicy=resizecrop&rw=500&rh=280) ### Horse Sanctuary & Trail Ride 3h 10/10 4 reviews Free cancellation available ~~£78~~£69 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/horse-riding-trail-in-ancient-rome.a1146828.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Rome's Hidden Excavations: Underground Tunnels & Colosseum Tour](https://mediaim.expedia.com/localexpert/2126119/a48faaba-5051-4924-b519-53cceb3c80d1.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome's Hidden Excavations: Underground Tunnels & Colosseum Tour 4h Free cancellation available £78 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/1-hour-colosseum-exclusive-private-guided-tour-no-line-pickup-drop-off-option.a2126119.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Rome Highlights by Golf Cart: Private Tour](https://mediaim.expedia.com/localexpert/3617993/b5276f03-5ba6-4fd2-8d67-43236d876bf9.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome Highlights by Golf Cart: Private Tour 7h 9.6/10 15 reviews Free cancellation available ~~£316~~£268 includes taxes & fees per adult\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.co.uk/things-to-do/rome-by-golf-cart-private-tour.a3617993.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![In-depth Private or Shared Tour of St. Peter's Basilica, Square, & Grottoes](https://mediaim.expedia.com/localexpert/49212559/08ea0988-f7fb-4d6c-82a1-3d59b0b4662f.jpg?impolicy=resizecrop&rw=500&rh=280) ### In-depth Private or Shared Tour of St. Peter's Basilica, Square, & Grottoes 1h Free cancellation available £22 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/in-depth-private-or-shared-tour-of-st-peters-basilica-square-grottoes.a49212559.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Private or Small Group Tour of Ostia Antica with Transfer from Rome](https://mediaim.expedia.com/localexpert/49448519/3885d51e-bbd6-4d9d-b70d-58217e61d4d8.jpg?impolicy=resizecrop&rw=500&rh=280) ### Private or Small Group Tour of Ostia Antica with Transfer from Rome 2h 30m Free cancellation available £218 includes taxes & fees per adult\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.co.uk/things-to-do/private-or-small-group-tour-of-ostia-antica-with-transfer-from-rome.a49448519.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ### Food, drink & nightlife [See all 79 activities](https://expedia.co.uk/things-to-do/search?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&filter.categories=FoodDrinkNightlife) ![Learn to Make Pasta & Tiramisu with Wine and Limoncello Included](https://mediaim.expedia.com/localexpert/3087530/f87dc754-fe4a-40ab-968b-33ecea2028d9.jpg?impolicy=resizecrop&rw=500&rh=280) ### Learn to Make Pasta & Tiramisu with Wine and Limoncello Included 2h 9.8/10 25 reviews Free cancellation available £49 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/rome-cooking-class-fettuccine-tiramisu-lovers-workshop.a3087530.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![3 in 1 Cooking Class near Navona: Fettuccine, Ravioli & Tiramisu](https://mediaim.expedia.com/localexpert/2128072/99424690-45a6-41c0-80b9-d6dd8583fa44.jpg?impolicy=resizecrop&rw=500&rh=280) ### 3 in 1 Cooking Class near Navona: Fettuccine, Ravioli & Tiramisu 3h 9.6/10 60 reviews Free cancellation available ~~£61~~£51 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/3-in-1-cooking-class-piazza-navona-fettuccine-ravioli-and-tiramisu.a2128072.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Rome Food Tour: Hidden Gems of Trastevere with Dinner & Wine](https://mediaim.expedia.com/localexpert/1088407/cc51bcb9-036a-433d-adde-e731983a97fc.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome Food Tour: Hidden Gems of Trastevere with Dinner & Wine 3h 9.2/10 23 reviews Free cancellation available £63 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/hidden-rome-food-tour-in-trastevere-with-dinner-and-wine.a1088407.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![VIP Vatican Breakfast with Vatican Museums & Sistine Chapel Guided Tour](https://mediaim.expedia.com/localexpert/166608/8447e5f4-3c26-475b-beb8-84f570ef6336.jpg?impolicy=resizecrop&rw=500&rh=280) ### VIP Vatican Breakfast with Vatican Museums & Sistine Chapel Guided Tour 3h 9.2/10 105 reviews £139 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/vip-vatican-breakfast-sistine-chapel-and-st-peters-basilica-guided-tour.a166608.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Rome Food Tour: Unlimited Tastings with Fine Wine & Barolo](https://mediaim.expedia.com/localexpert/1012378/acd7e3f4-e1d1-4ca6-8f4f-73dbd81ae671.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome Food Tour: Unlimited Tastings with Fine Wine & Barolo 4h 9.8/10 40 reviews Free cancellation available £60 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/rome-food-wine-tour-in-prati.a1012378.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Hard Rock Cafe Rome Dining With Priority Seating](https://mediaim.expedia.com/localexpert/166407/58ebabf9-3a32-4b55-a78a-68f7d129d215.jpg?impolicy=resizecrop&rw=500&rh=280) ### Hard Rock Cafe Rome Dining With Priority Seating 2h 9/10 190 reviews Free cancellation available £24 includes taxes & fees per traveller [](https://www.expedia.co.uk/things-to-do/hard-rock-cafe-rome-dining-with-priority-seating.a166407.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Rome Street Food Tour with Local Guide](https://mediaim.expedia.com/localexpert/2124035/14fd9e77-2f7a-4a8e-86bb-f26685ffa41a.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome Street Food Tour with Local Guide 2h 30m 10/10 11 reviews Free cancellation available £39 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/rome-street-food-tour-with-local-guide.a2124035.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Trastevere Food tour with Free-Flowing Fine Wine, Rome](https://mediaim.expedia.com/localexpert/1012380/ea071694-fbc0-45bf-b793-013e9ed83055.jpg?impolicy=resizecrop&rw=500&rh=280) ### Trastevere Food tour with Free-Flowing Fine Wine, Rome 4h 9.8/10 46 reviews Free cancellation available £110 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/the-roman-food-tour-in-trastevere-with-free-flowing-fine-wine.a1012380.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Pasta-Making Class: Cook, Dine & Drink With A Local Chef](https://mediaim.expedia.com/localexpert/263177/9645d4ca-bc3b-415f-961c-d17a85c73f7c.jpg?impolicy=resizecrop&rw=500&rh=280) ### Pasta-Making Class: Cook, Dine & Drink With A Local Chef 3h 10/10 131 reviews Free cancellation available £52 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/pasta-making-class-cook-dine-drink-with-a-local-chef.a263177.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Rome Cooking Class: Make Pizza and Pasta with Wine & Dessert](https://mediaim.expedia.com/localexpert/1182002/1cc696ba-8268-44cf-909e-72bbe3ccf7dd.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome Cooking Class: Make Pizza and Pasta with Wine & Dessert 3h 30m Free cancellation available ~~£49~~£44 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/pizza-and-pasta-master-class-with-wine-and-tiramisu-on-the-ancient-appian-way.a1182002.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ### Attractions [See all 18 activities](https://expedia.co.uk/things-to-do/search?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&filter.categories=Attractions) ![Skip-the-Line: Vatican Museums & Sistine Chapel Admission with Audio Guide](https://mediaim.expedia.com/localexpert/166616/f2175269-46b3-43bb-ace2-8a45a3aa1950.jpg?impolicy=resizecrop&rw=500&rh=280) ### Skip-the-Line: Vatican Museums & Sistine Chapel Admission with Audio Guide 1h 7.6/10 956 reviews Free cancellation available £34 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/skip-the-line-vatican-museums-sistine-chapel-admission-with-audio-guide.a166616.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Skip the Line: Vatican Museums & Sistine Chapel + Optional Basilica](https://mediaim.expedia.com/localexpert/490292/454636b9-24b4-49a9-aa16-c4a18321ca1e.jpg?impolicy=resizecrop&rw=500&rh=280) ### Skip the Line: Vatican Museums & Sistine Chapel + Optional Basilica 1h 30m+ 8.8/10 1,010 reviews Free cancellation available £33 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/skip-the-line-vatican-museums-sistine-chapel-tickets-or-tours.a490292.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Papal Audience with Pope Leo XIV – Vatican Blessing Tour](https://mediaim.expedia.com/localexpert/166516/524a5106-2137-42b9-ae55-e253ac9b7576.jpg?impolicy=resizecrop&rw=500&rh=280) ### Papal Audience with Pope Leo XIV – Vatican Blessing Tour 4h 30m 6.8/10 180 reviews Free cancellation available £31 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/papal-audience-with-pope-leo-xiv-vatican-blessing-tour.a166516.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Rome: Best of Rome Pass](https://mediaim.expedia.com/localexpert/500358/c70a5bbe-388f-4e0f-8419-537215ef47e3.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: Best of Rome Pass 3d 7.2/10 36 reviews £92 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/best-of-rome-pass-all-access-pass-with-reserved-entrance.a500358.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Arena of Colosseum, Roman Forum and Palatine Hill with Multimedia Video](https://mediaim.expedia.com/localexpert/44938942/29c8e2c5-94d4-4312-9fec-16c04a28cb1a.jpg?impolicy=resizecrop&rw=500&rh=280) ### Arena of Colosseum, Roman Forum and Palatine Hill with Multimedia Video 4h 8/10 1 review £42 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/colosseum-with-arena-skip-the-line-entrance.a44938942.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Reserved entrance: Vatican Museums Tickets with Hosted Entry](https://mediaim.expedia.com/localexpert/500360/b5cf98dc-7f60-4909-a877-fb3e58718a86.jpg?impolicy=resizecrop&rw=500&rh=280) ### Reserved entrance: Vatican Museums Tickets with Hosted Entry 3h 7.6/10 24 reviews £50 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/reserved-entrance-vatican-museums-tickets-with-hosted-entry.a500360.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Roma Pass: Official City Card with Transport](https://mediaim.expedia.com/localexpert/4517067/ead2a7b2-391c-408f-83ea-205d45bcc582.jpg?impolicy=resizecrop&rw=500&rh=280) ### Roma Pass: Official City Card with Transport 4/10 6 reviews Free cancellation available £49 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/roma-pass-48-hour-city-card-with-transport.a4517067.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Breakfast in the Vatican Museums](https://mediaim.expedia.com/localexpert/47280924/ac1284c0-1bf6-4aaf-9d51-e1ff1216e737.jpg?impolicy=resizecrop&rw=500&rh=280) ### Breakfast in the Vatican Museums 4h 8/10 1 review £75 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/breakfast-in-the-vatican-museums.a47280924.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Skip-the-Line: Vatican Museums & Sistine Chapel Ticket with Audio Guide](https://mediaim.expedia.com/localexpert/47322589/ba90951a-4535-41c7-bf61-398747b98f5c.jpg?impolicy=resizecrop&rw=500&rh=280) ### Skip-the-Line: Vatican Museums & Sistine Chapel Ticket with Audio Guide 1h 30m Free cancellation available £34 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/skip-the-line-vatican-museums-sistine-chapel-ticket-with-audio-guide.a47322589.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Colosseum Roman Forum and Palatine Hill Entrance in Rome](https://mediaim.expedia.com/localexpert/50714773/308847af-92de-41ee-81c1-d21406d4e327.jpg?impolicy=resizecrop&rw=500&rh=280) ### Colosseum Roman Forum and Palatine Hill Entrance in Rome 4h £35 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/colosseum-roman-forum-and-palatine-hill-entrance-in-rome.a50714773.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ### Shows & concerts [See all 10 activities](https://expedia.co.uk/things-to-do/search?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&filter.categories=ShowsConcerts) ![Rome: "The Most Beautiful Opera Arias" Concert](https://mediaim.expedia.com/localexpert/4776930/5eb620bd-c63e-4e94-a260-bccfd0593383.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: "The Most Beautiful Opera Arias" Concert 50m 8.2/10 25 reviews Free cancellation available £30 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/rome-the-most-beautiful-opera-arias-concert.a4776930.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Welcome To Rome Experience](https://mediaim.expedia.com/localexpert/1204768/f67f84b2-5a83-4c7e-bdb8-758208cb641a.jpg?impolicy=resizecrop&rw=500&rh=280) ### Welcome To Rome Experience 1h 9.4/10 3 reviews Free cancellation available ~~£16~~£14 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/welcome-to-rome-experience.a1204768.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![The Three Tenors Concert in St. Paul's Within the Walls](https://mediaim.expedia.com/localexpert/733801/b6197d60-fcfa-459b-903c-8488e16b7072.jpg?impolicy=resizecrop&rw=500&rh=280) ### The Three Tenors Concert in St. Paul's Within the Walls 2h 9.6/10 9 reviews Free cancellation available £29 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/the-three-tenors-concert-in-st-pauls-within-the-walls.a733801.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Rome: Italian Opera Concert and Traditional Dinner](https://mediaim.expedia.com/localexpert/47875709/00ed299e-8a03-42a0-be5d-511dea604617.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: Italian Opera Concert and Traditional Dinner 2h 6/10 1 review Free cancellation available £70 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/rome-italian-opera-concert-and-traditional-dinner.a47875709.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![La Traviata The Original Opera by Giuseppe Verdi](https://mediaim.expedia.com/localexpert/728499/8e071bfa-27dc-44ae-bced-3b5a8d5e5a47.jpg?impolicy=resizecrop&rw=500&rh=280) ### La Traviata The Original Opera by Giuseppe Verdi 2h 8/10 4 reviews Free cancellation available £29 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/la-traviata-the-original-opera-with-ballet.a728499.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Freddie Mercury Opera Show in Rome](https://mediaim.expedia.com/localexpert/49782161/c0871b11-8acb-409f-9cdb-aa90cfe79353.jpg?impolicy=resizecrop&rw=500&rh=280) ### Freddie Mercury Opera Show in Rome 1h 6/10 1 review Free cancellation available £37 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/freddie-mercury-opera-show-in-rome.a49782161.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![Rome: Chopin & Italian Friends Piano Concert](https://mediaim.expedia.com/localexpert/50006958/8da4d54f-857e-4e29-9a4b-f3e3741e948b.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: Chopin & Italian Friends Piano Concert 50m Free cancellation available £28 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/rome-chopin-italian-friends-piano-concert.a50006958.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ![A night at Opera Experience](https://mediaim.expedia.com/localexpert/571987/83a9ab83-eabb-461c-9388-89bdaab51ef9.jpg?impolicy=resizecrop&rw=500&rh=280) ### A night at Opera Experience 3h Free cancellation available £32 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/a-night-at-opera-experience.a571987.activity-details?&rid=553248621533001950&location=Basilica+of+Santi+Cosma+e+Damiano&swp=off) ### Popular places to visit ![Imperial Fora](https://mediaim.expedia.com/destination/1/413a028298ad2dcfa3e9904dd3ebab8f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Imperial Fora 4.5/5(19 reviews) You can find out about the history of Rome with a visit to Imperial Fora. Discover the acclaimed art galleries and stunning cathedral in this vibrant area. [](https://expedia.co.uk/Imperial-Fora-Rome.d502480.Attraction) ![Santa Francesca Romana showing heritage architecture](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/99000/99613-Santa-Francesca-Romana.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Santa Francesca Romana Featuring an impressive Italian bell tower, this 10th-century minor basilica holds precious religious artworks and the relics of St. Francesca Romana. [](https://expedia.co.uk/Santa-Francesca-Romana-Rome-City-Centre.d6146983.Attraction) ![Temple of Castor and Pollux](https://mediaim.expedia.com/destination/1/f5a32f2a755c3eb458a846106af79ce7.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Temple of Castor and Pollux You can find out about the history of Rome when you stop by Temple of Castor and Pollux. Visit the churches and notable monuments in this vibrant area. [](https://expedia.co.uk/Temple-Of-Castor-And-Pollux-Rome-City-Centre.d553248621533001633.Attraction) ![Curia Julia](https://mediaim.expedia.com/destination/2/34fed27efa9905a6bf1eaa0d764a12a1.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Curia Julia You can learn about the history of Rome when you stop by Curia Julia. Visit the churches and notable monuments in this vibrant area. [](https://expedia.co.uk/Curia-Julia-Rome.d553248621532500824.Attraction) ![Arch of Titus](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/208000/208218-Arch-Of-Titus.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Arch of Titus Learn about the battles of the Roman Empire, examine the detailed carvings or just admire the skills required to build this ancient symbol of victory. [](https://expedia.co.uk/Arch-Of-Titus-Rome-City-Centre.d6073984.Attraction) ![Roman Forum](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/20000/20273-Roman-Forum.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Roman Forum 4.5/5(1,964 reviews) Explore one of the most renowned archaeological sites in the world and immerse yourself in the ancient atmosphere where the Roman Empire began. [](https://expedia.co.uk/Roman-Forum-Rome-City-Centre.d502481.Attraction) --- ## Top Hotel Deals ## Check availability on hotels close to Basilica of Santi Cosma e Damiano [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621533001950&startDate=2025-12-12&endDate=2025-12-13)[12 Dec - 13 Dec](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621533001950&startDate=2025-12-12&endDate=2025-12-13) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621533001950&startDate=2025-12-13&endDate=2025-12-14)[13 Dec - 14 Dec](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621533001950&startDate=2025-12-13&endDate=2025-12-14) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621533001950&startDate=12%2F12%2F2025&endDate=14%2F12%2F2025)[12 Dec - 14 Dec](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621533001950&startDate=12%2F12%2F2025&endDate=14%2F12%2F2025) ![Hotel Quirinale](https://images.trvl-media.com/lodging/1000000/10000/1100/1058/df3b5a06_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Quirinale Via Nazionale 7 Rome RM [](https://expedia.co.uk/Rome-Hotels-Hotel-Quirinale.h1058.Hotel-Information) ![The Hive Hotel](https://images.trvl-media.com/lodging/25000000/24470000/24463300/24463268/ec6c185a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Hive Hotel Via Torino 6 Rome RM [](https://expedia.co.uk/Rome-Hotels-The-Hive-Hotel.h24463268.Hotel-Information) ![UNA Hotels Decò Roma](https://images.trvl-media.com/lodging/3000000/2230000/2222500/2222425/f97ca989_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### UNA Hotels Decò Roma Via Giovanni Amendola, 57 Rome RM [](https://expedia.co.uk/Rome-Hotels-UNAHOTELS-Deco-Roma.h2222425.Hotel-Information) ![Hotel Delle Nazioni](https://images.trvl-media.com/lodging/1000000/60000/54200/54154/104d793e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Delle Nazioni Via Poli 7 Rome RM [](https://expedia.co.uk/Rome-Hotels-Hotel-Delle-Nazioni.h54154.Hotel-Information) ![Hotel Artemide](https://images.trvl-media.com/lodging/1000000/50000/45900/45856/dccbfa6d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Artemide Via Nazionale 22 Rome RM [](https://expedia.co.uk/Rome-Hotels-Hotel-Artemide.h45856.Hotel-Information) ![Bettoja Hotel Mediterraneo](https://images.trvl-media.com/lodging/1000000/10000/8800/8711/05f1eca2_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Bettoja Hotel Mediterraneo Via Cavour 15 Rome RM [](https://expedia.co.uk/Rome-Hotels-Bettoja-Hotel-Mediterraneo.h8711.Hotel-Information) ![The Glam](https://images.trvl-media.com/lodging/16000000/15340000/15335900/15335833/cf908ad0_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Glam Via Nazionale 82 Rome RM [](https://expedia.co.uk/Rome-Hotels-The-Glam.h15335833.Hotel-Information) ![Excellence Suite](https://images.trvl-media.com/lodging/15000000/14620000/14617000/14616938/5c2b5d7f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Excellence Suite Via della Purificazione 38 Rome RM [](https://expedia.co.uk/Rome-Hotels-Excellence-Suite.h14616938.Hotel-Information) ![Trastevere Roma | UNA Esperienze](https://images.trvl-media.com/lodging/75000000/74060000/74055900/74055827/0d267171_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Trastevere Roma | UNA Esperienze Via Emilio Morosini 27 Rome RM [](https://expedia.co.uk/Rome-Hotels-UNAHOTELS-Trastevere-Roma.h74055827.Hotel-Information) [See all 14,982 properties in Basilica of Santi Cosma e Damiano](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=553248621533001950) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. 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