Title: Hotels in Advance, MO - Best Advance Hotels from £46 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Advance](https://expedia.co.uk/Advance-Holiday-Rentals.d553248634983475122.Travel-Guide-HolidayRentals)[Advance Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Advance.d553248634983475122.Car-Hire-Guide)[Advance Holidays](https://expedia.co.uk/Advance.d553248634983475122.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Advance, MO from £46 ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Advance Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Advance%2C+Missouri%2C+United+States+of+America®ionId=553248634983475122&latLong=37.104496%2C-89.910652&adults=2&startDate=2025-10-16&d1=2025-10-16&endDate=2025-10-18&d2=2025-10-18&amenities=POOL) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Advance%2C+Missouri%2C+United+States+of+America®ionId=553248634983475122&latLong=37.104496%2C-89.910652&adults=2&startDate=2025-10-16&d1=2025-10-16&endDate=2025-10-18&d2=2025-10-18&travelerType=family_friendly) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Advance%2C+Missouri%2C+United+States+of+America®ionId=553248634983475122&latLong=37.104496%2C-89.910652&adults=2&startDate=2025-10-16&d1=2025-10-16&endDate=2025-10-18&d2=2025-10-18&amenities=PETS) ## Check prices for these dates Tonight [2 Oct - 3 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983475122&startDate=2025-10-02&endDate=2025-10-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [3 Oct - 4 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983475122&startDate=2025-10-03&endDate=2025-10-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [3 Oct - 5 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983475122&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983475122&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top 10 Advance hotels and places to stay ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/686f0126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/4abadc7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Sikeston Sikeston 8.8/10 Excellent (402) "Nice property and friendly staff." £85 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/860000/856200/856148/4768517d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/860000/856200/856148/f3b3697d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/860000/856200/856148/3f1c7b51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/860000/856200/856148/9a624d3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dexter Inn Dexter 6.8/10 (323) "Been a good stay every night" £50 includes taxes & fees 3 Oct - 4 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Dexter-Inn.h856148.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/d0828685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/132cb18c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Jackson MO Jackson 9.6/10 Exceptional (1002) "Was a clean room, nice staff, good parking " £71 includes taxes & fees 7 Oct - 8 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Single Room, 1 King Bed, Non Smoking (Mobility, Bathtub w/Grab Bars) | Hypo-allergenic bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/67f5d6f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/8571b84d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Jackson 8.8/10 Excellent (629) "Friendly staff, very clean and pleasant environment." £68 includes taxes & fees 5 Oct - 6 Oct [](https://www.expedia.co.uk/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/90000/84800/84779/8be70c86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking | Desk, blackout curtains, iron/ironing board, free rollaway beds](https://images.trvl-media.com/lodging/1000000/90000/84800/84779/f5deab1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/90000/84800/84779/eea0b1f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/90000/84800/84779/8865f485.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Dexter Dexter 7.4/10 Good (371) "Currently the best option in Dexter. The upgrade from a couple of years ago is standing up to the wear and tear of the use." £62 includes taxes & fees 5 Oct - 6 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Travelodge-By-Wyndham-Dexter.h84779.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8 AM to 11 PM, pool loungers](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/65f9cbe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/1fd79e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, down duvets, desk](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/7dc8a5d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Sikeston Southwest by IHG Sikeston 8.6/10 Excellent (431) "Clean and nice facilities. All the staff we met were friendly and helpful. Breakfast was great." £88 includes taxes & fees 17 Oct - 18 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/6497a67e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast ](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/dcdd1977.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/e5416d3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/59b72b64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Dexter Dexter 6.8/10 (244) "Rough parking lot, sparse lobby, ok for one night on a trip, not a vacation spot" £46 includes taxes & fees 1 Nov - 2 Nov [](https://www.expedia.co.uk/Sikeston-Hotels-Econo-Lodge-Dexter.h437691.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/284f2de7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/f32a343b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/032aa313.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau West Cape Girardeau 9.0/10 Wonderful (1000) "My room was clean and I was very close to shopping and restaurants. I really enjoyed my stay there." £59 includes taxes & fees 5 Oct - 6 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Economy Single Room, 1 Queen Bed, Kitchenette | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/1aa84b52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/6f6795dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Single Room, 1 Queen Bed, Kitchenette | Bathroom | Hair dryer, towels](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/324e501c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn Jackson 7.6/10 Good (416) "It was easy and quiet and an easy check in " £56 includes taxes & fees 5 Oct - 6 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/ee6292b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/2df4267b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/4ea3df4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau Near the Medical Center Cape Girardeau 9.0/10 Wonderful (1002) "Room was clean, it is an affordable option to stay for a day or two " £59 includes taxes & fees 6 Oct - 7 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/05f90b2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/c56432e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/5b2269be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Cape Girardeau Cape Girardeau 9.4/10 Exceptional (1000) "Excellent place. Really friendly staff" £75 includes taxes & fees 7 Oct - 8 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast ](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/5fa70c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8 AM to 11 PM, pool loungers](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/64fb9857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/eb2507f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Cape Girardeau 9.4/10 Exceptional (1002) "It was right off the interstate with lots of restaurant options " £79 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/16f1820b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/6f9bce18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c279dc08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Cape Girardeau Conference Center Cape Girardeau 9.6/10 Exceptional (1001) "Clean, friendly staff and business friendly " £75 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, Egyptian cotton sheets, premium bedding, down duvets](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/68c09770.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/18325925.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/20bc712d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Cape Girardeau Downtown Cape Girardeau 9.6/10 Exceptional (454) "The Staff was friendly The restaurant was good" £105 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152272/012f90a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152272/e8c32cdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152272/415149fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152272/02df00ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### OYO Hickory House Inn Dexter 5.4/10 (125) "Nice room very comfortable bed's" £49 includes taxes & fees 4 Oct - 5 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Hickory-House-Inn.h1152272.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/f2cf9c54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/27c728aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Hypo-allergenic bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/39cbec08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Sikeston Sikeston 9.4/10 Exceptional (25) "Hotel was clean, the toilets could use some attention, but staff was friendly and the breakfast was good" £85 includes taxes & fees 16 Oct - 17 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/540ce58d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/acc0b9b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/cfaba55a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/0578314a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Cape Girardeau I 55 East Cape Girardeau 9.6/10 Exceptional (748) "Would prefer onsite restaurant and bar" £92 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information) ![Standard Room, 1 Queen Bed, Non Smoking, Garden View | Free WiFi](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/fc499141.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/a102ce70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking | Free WiFi](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/000a3467.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/dbe031d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rockwood Inn Cape Girardeau 10/10 Exceptional (16) "We came into town for a concert and had a blast! The hotel was super comfy, and the staff were friendly. The rooms were very clean and the decor was beautiful! " £117 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Rockwood-Inn.h105486893.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible, Non Smoking | Egyptian cotton sheets, premium bedding, down duvets, memory-foam beds](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/9a57fa49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily English breakfast ](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/e034ecf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down duvets, memory-foam beds](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/c5d3f974.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cape Girardeau 7.2/10 Good (644) "nice stay" £48 includes taxes & fees 9 Oct - 10 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/347bcd98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/266a85bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/6cd5cd8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/51a3fe78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Cape Girardeau Cape Girardeau 9.4/10 Exceptional (129) "Excellent hotel…" £78 includes taxes & fees 9 Oct - 10 Oct [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-16&endDate=2025-10-17®ionId=553248634983475122&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FAdvance-Hotels.d553248634983475122.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FAdvance-Hotels.d553248634983475122.Travel-Guide-Hotels) ## Top Advance Hotel Reviews ![Hampton Inn Sikeston](//images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg) ### Hampton Inn Sikeston 10/10 Excellent "Everything was enjoyable and the staff was top notch. " [](https://expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](//images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg) ### Pear Tree Inn Cape Girardeau Near the Medical Center 10/10 Excellent "Very convenient and felt safe" [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](//images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "This is the best hotel experience for the price that I’ve ever had, and I travel a lot. Very generous social time with three free drinks and lots of complementary food. Everyone was lovely, bed comfortable, perfect temperature and no stale smell. Very clean. And so well priced! I wish all hotels were like this one!" [](https://expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![The Riverview](//images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg) ### The Riverview 10/10 Excellent "Hotel was very close to the Show Me Center. Very clean, quiet and comfortable room." [](https://expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Drury Inn & Suites Jackson MO](//images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 10/10 Excellent "We just came in for one night to see our grandson play football. We come to Jackson often and always stay here. It is consistently excellent. Clean, friendly, staff is great. " [](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Tru By Hilton Cape Girardeau](//images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg) ### Tru By Hilton Cape Girardeau 10/10 Excellent "Beautiful hotel. Very clean, modern and friendly staff. Definitely would recommend to anyone coming to that area and will stay there every time we visit the city." [](https://expedia.co.uk/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](//images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 10/10 Excellent "Everything was clean and looked newly renovated. Staff was friendly. Parking was convenient and the area seemed safe. " [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Fairfield Inn & Suites by Marriott Cape Girardeau](//images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/347bcd98_y.jpg) ### Fairfield Inn & Suites by Marriott Cape Girardeau 10/10 Excellent "Excellent hotel…" [](https://expedia.co.uk/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ![Drury Inn & Suites Cape Girardeau](//images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg) ### Drury Inn & Suites Cape Girardeau 10/10 Excellent "Overall great " [](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ## More cheap stays in Advance ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Riverview 777 Main St, Cape Girardeau, MO £103 19 Oct - 20 Oct includes taxes & fees 9.2/10 Wonderful! (428 reviews) [](https://expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau Near the Medical Center 3248 William St, Cape Girardeau, MO £59 6 Oct - 7 Oct includes taxes & fees 8.8/10 Excellent! (1,011 reviews) [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau West 103 Cape West Pkwy, Cape Girardeau, MO £59 5 Oct - 6 Oct includes taxes & fees 9/10 Wonderful! (1,012 reviews) [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Sikeston 1240 Commerce Drive, Sikeston, MO £85 12 Oct - 13 Oct includes taxes & fees 8.8/10 Excellent! (401 reviews) [](https://expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG 3253 William Street, Cape Girardeau, MO £79 19 Oct - 20 Oct includes taxes & fees 9.4/10 Exceptional! (1,000 reviews) [](https://expedia.co.uk/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Fairfield Inn & Suites by Marriott Cape Girardeau](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/347bcd98_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Fairfield Inn & Suites by Marriott Cape Girardeau 433 CAPE WEST CROSSINGS, Cape Girardeau, MO £78 9 Oct - 10 Oct includes taxes & fees 9.2/10 Wonderful! (129 reviews) [](https://expedia.co.uk/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Accommodation near Advance attractions - [Hotels near Shawnee National Forest](https://expedia.co.uk/Shawnee-National-Forest-Hotels.0-l553248635944113522-0.Travel-Guide-Filter-Hotels) - [Hotels near Mississippi River](https://expedia.co.uk/Mississippi-River-Hotels.0-l6209928-0.Travel-Guide-Filter-Hotels) - [Hotels near Southeast Missouri State University](https://expedia.co.uk/Southeast-Missouri-State-University-Hotels.0-l553248621554122994-0.Travel-Guide-Filter-Hotels) ### Hotels Near Advance, Missouri - [Cape Girardeau Hotels](https://expedia.co.uk/Cape-Girardeau-Hotels.d820.Travel-Guide-Hotels) - [Sikeston Hotels](https://expedia.co.uk/Sikeston-Hotels.d6058766.Travel-Guide-Hotels) - [Poplar Bluff Hotels](https://expedia.co.uk/Poplar-Bluff-Hotels.d9449.Travel-Guide-Hotels) - 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Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)