A narrow cobblestone street lined with colorful buildings, shops, and a prominent white archway in the distance.

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Check availability on Santa Cruz 5 Star Hotels

Our top choices for Santa Cruz 5-star hotels

A large, ornate building with multiple balconies and a central dome, surrounded by palm trees.

1. Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
5.0 star property
Historical Center
9.4 out of 10, Exceptional, (1,000 reviews)
"Excellent hotel"
Mexico
Richard
The price is £419
includes taxes & fees
1 Sept - 2 Sept
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
A historic building with intricate architecture, a covered outdoor seating area, and a view of the structure.

2. EME Catedral Mercer Hotel

EME Catedral Mercer Hotel
5.0 star property
Historical Center
8.8 out of 10, Excellent, (1,006 reviews)
The price is £149
includes taxes & fees
2 Sept - 3 Sept
EME Catedral Mercer Hotel
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Cruz.
Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center

Calle Santa Maria La Blanca 5 Seville Seville
The price is £128 per night from 1 Sept to 2 Sept
£128
1 Sept - 2 Sept
includes taxes & fees
9.2/10 Wonderful! (1,002 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Santa Cruz Hotel Reviews

EME Catedral Mercer Hotel

EME Catedral Mercer Hotel

10/10 Excellent
"Lovely hotel with amazing views of the cathedral"
Andrew 2-night trip
Posted 9 hours ago
EME Catedral Mercer Hotel

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