Title: The 10 Best 5 Star Hotels in Mediterranean Region - 2026 Updated Prices | Expedia.co.uk [Mediterranean Region Travel Guide](https://expedia.co.uk/Mediterranean-Region.dx844522342175883264)[Hotels in Mediterranean Region](https://expedia.co.uk/Mediterranean-Region-Hotels.d844522342175883264.Travel-Guide-Hotels)[Holiday Rentals in Mediterranean Region](https://expedia.co.uk/Mediterranean-Region-Holiday-Rentals.d844522342175883264.Travel-Guide-HolidayRentals)[Flights to Mediterranean Region](https://expedia.co.uk/Cheap-Flights-To-Mediterranean-Region.d844522342175883264.Travel-Guide-Flights)[Mediterranean Region Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mediterranean-Region.d844522342175883264.Car-Hire-Guide)[Mediterranean Region Holidays](https://expedia.co.uk/Mediterranean-Region.d844522342175883264.Holidays-City-Breaks) ![Mazarrón, Spain](https://images.trvl-media.com/place/553248633936349954/597750c4-7c4e-4a36-b33c-904705e647c4.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Compare and book 5 Star hotels in Mediterranean Region, - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mediterranean Region 5 Star Hotels Tonight [30 Dec - 31 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=844522342175883264&startDate=2025-12-30&endDate=2025-12-31&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [31 Dec - 1 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=844522342175883264&startDate=2025-12-31&endDate=2026-01-01&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=844522342175883264&startDate=2026-01-02&endDate=2026-01-04&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [9 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=844522342175883264&startDate=2026-01-09&endDate=2026-01-11&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mediterranean Region 5-star hotels ![Mediterranean cuisine](https://images.trvl-media.com/lodging/1000000/30000/21100/21031/dbfe795f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21100/21031/w3837h2559x3y0-1cfc3e1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed (Penthouse) | Minibar, in-room safe, desk, soundproofing](https://images.trvl-media.com/lodging/1000000/30000/21100/21031/45d10bd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/30000/21100/21031/595f7b89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hyatt Athens [](https://www.expedia.co.uk/Athens-Hotels-Grand-Hyatt-Athens.h21031.Hotel-Information) Neos Kosmos 8.8/10 Excellent (1011) "Amenities were great, food was delicious, and the staff was very friendly!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Orlando £87 includes taxes & fees 18 Jan - 19 Jan 2026 [](https://www.expedia.co.uk/Athens-Hotels-Grand-Hyatt-Athens.h21031.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/10000/3400/3388/a07cf64a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served, Spanish cuisine](https://images.trvl-media.com/lodging/1000000/10000/3400/3388/9b2b1f33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/3400/3388/9f1f2700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/3400/3388/722ac0b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lamaro Hotel [](https://www.expedia.co.uk/Barcelona-Hotels-Hotel-Colon-Barcelona.h3388.Hotel-Information) Downtown Barcelona 9.6/10 Exceptional (1839) "Excellent location, staff and property." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Suhail £180 includes taxes & fees 25 Jan - 26 Jan 2026 [](https://www.expedia.co.uk/Barcelona-Hotels-Hotel-Colon-Barcelona.h3388.Hotel-Information) ![Cocktail bar](https://images.trvl-media.com/lodging/2000000/1340000/1338000/1337977/3f36a705.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1340000/1338000/1337977/195f35b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, pool loungers](https://images.trvl-media.com/lodging/2000000/1340000/1338000/1337977/26a7a198.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, in-room safe, blackout curtains, soundproofing](https://images.trvl-media.com/lodging/2000000/1340000/1338000/1337977/51de29f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Barcelona Tower [](https://www.expedia.co.uk/Barcelona-Hotels-Hyatt-Regency-Barcelona-Tower.h1337977.Hotel-Information) Bellvitge 9.0/10 Wonderful (1014) "Good hotel / so so location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jacques £124 includes taxes & fees 11 Jan - 12 Jan 2026 [](https://www.expedia.co.uk/Barcelona-Hotels-Hyatt-Regency-Barcelona-Tower.h1337977.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11000/10975/06dc3039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11000/10975/5d5b94de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/11000/10975/cad83751.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/20000/11000/10975/ab54efdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Palace, a Luxury Collection Hotel, Madrid [](https://www.expedia.co.uk/Madrid-Hotels-The-Palace.h10975.Hotel-Information) Madrid Centro 9.2/10 Wonderful (1006) "Excellent clan beautifully laid out very comfortable Great hotel must stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mona £303 includes taxes & fees 5 Jan - 6 Jan 2026 [](https://www.expedia.co.uk/Madrid-Hotels-The-Palace.h10975.Hotel-Information) ![Premium bedding, Select Comfort beds, minibar, in-room safe](https://images.trvl-media.com/lodging/16000000/15380000/15372000/15371941/17643795.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, pool loungers](https://images.trvl-media.com/lodging/16000000/15380000/15372000/15371941/807e046f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, Select Comfort beds, minibar, in-room safe](https://images.trvl-media.com/lodging/16000000/15380000/15372000/15371941/8f047351.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/16000000/15380000/15372000/15371941/3792e200.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Barceló Torre de Madrid [](https://www.expedia.co.uk/Madrid-Hotels-Barcelo-Torre-De-Madrid.h15371941.Hotel-Information) Madrid Centro 9.6/10 Exceptional (2285) "Great hotel with polite and friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Conrad £160 includes taxes & fees 11 Jan - 12 Jan 2026 [](https://www.expedia.co.uk/Madrid-Hotels-Barcelo-Torre-De-Madrid.h15371941.Hotel-Information) ![Outdoor pool, open 10:00 AM to 9:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/11800/11761/w4000h2696x0y0-6b03216b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/20000/11800/11761/w3611h2700x590y0-e68003ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/20000/11800/11761/6957a448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11800/11761/w3602h2700x599y0-6dfb7d2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Only YOU Hotel Sevilla [](https://www.expedia.co.uk/Seville-Hotels-Ayre-Hotel-Sevilla.h11761.Hotel-Information) San Pablo-Santa Justa 9.8/10 Exceptional (588) "The rooms were comfortable, the staff very friendly, the hotel location was great and they have an amazing breakfast buffet. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Keymaris £83 includes taxes & fees 14 Jan - 15 Jan 2026 [](https://www.expedia.co.uk/Seville-Hotels-Ayre-Hotel-Sevilla.h11761.Hotel-Information) ![Couples treatment room(s), body treatments, body scrubs, facials](https://images.trvl-media.com/lodging/1000000/690000/688200/688125/d8b343ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges](https://images.trvl-media.com/lodging/1000000/690000/688200/688125/df5e7ec7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/690000/688200/688125/b6f405e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 Queen Bed | Premium bedding, memory-foam beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/690000/688200/688125/b8626219.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sofitel Athens Airport [](https://www.expedia.co.uk/Athens-Hotels-Sofitel-Athens-Airport.h688125.Hotel-Information) Spata-Artemida 9.4/10 Exceptional (2618) "It was a great place to stay and eat." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) susan £214 includes taxes & fees 22 Jan - 23 Jan 2026 [](https://www.expedia.co.uk/Athens-Hotels-Sofitel-Athens-Airport.h688125.Hotel-Information) ![Japanese cuisine](https://images.trvl-media.com/lodging/40000000/39070000/39067400/39067368/de597f46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, lobby lounge](https://images.trvl-media.com/lodging/40000000/39070000/39067400/39067368/f8751bcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Nobu Suite) | Egyptian cotton sheets, premium bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/40000000/39070000/39067400/39067368/aad463a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Sake) | City view](https://images.trvl-media.com/lodging/40000000/39070000/39067400/39067368/fc4fdb1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nobu Hotel Barcelona [](https://www.expedia.co.uk/Barcelona-Hotels-Nobu-Hotel-Barcelona.h39067368.Hotel-Information) Sants-Montjuïc 9.0/10 Wonderful (1194) "Excellent staff , great location, nice and clean set up " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marianna £191 includes taxes & fees 13 Jan - 14 Jan 2026 [](https://www.expedia.co.uk/Barcelona-Hotels-Nobu-Hotel-Barcelona.h39067368.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/5100/5002/1d089f4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/10000/5100/5002/d80c7ad5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Mediterranean cuisine ](https://images.trvl-media.com/lodging/1000000/10000/5100/5002/f0bcfd4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse | Premium bedding, down duvets, memory-foam beds, in-room safe](https://images.trvl-media.com/lodging/1000000/10000/5100/5002/6c3d2718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Majestic Hotel & Spa Barcelona [](https://www.expedia.co.uk/Barcelona-Hotels-Majestic-Hotel-Spa-Barcelona.h5002.Hotel-Information) Eixample 9.2/10 Wonderful (1002) "Great location. Wonderful hotel. Nice staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Myron £273 includes taxes & fees 14 Jan - 15 Jan 2026 [](https://www.expedia.co.uk/Barcelona-Hotels-Majestic-Hotel-Spa-Barcelona.h5002.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/880000/871900/871862/0cd6fac3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, individually furnished](https://images.trvl-media.com/lodging/1000000/880000/871900/871862/88083424.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, individually furnished](https://images.trvl-media.com/lodging/1000000/880000/871900/871862/c8a265eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/880000/871900/871862/aa413768.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Eurostars Grand Marina [](https://www.expedia.co.uk/Barcelona-Hotels-Eurostars-Grand-Marina.h871862.Hotel-Information) Downtown Barcelona 8.8/10 Excellent (1186) "Clean rooms, excellent location" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Amerjit £143 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Barcelona-Hotels-Eurostars-Grand-Marina.h871862.Hotel-Information) ![3 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/20000/19600/19591/639d39e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Club lounge access (Acropolis View) | 1 bedroom, premium bedding, down duvets, minibar](https://images.trvl-media.com/lodging/1000000/20000/19600/19591/e31612d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/20000/19600/19591/4e42dcf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/19600/19591/cc04ed54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Athenaeum InterContinental by IHG [](https://www.expedia.co.uk/Athens-Hotels-Athenaeum-InterContinental.h19591.Hotel-Information) Neos Kosmos 9.0/10 Wonderful (1002) "Glad we had a great stay! What stood out - clean room, staff, amenities, or something else" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mohammed £114 includes taxes & fees 11 Jan - 12 Jan 2026 [](https://www.expedia.co.uk/Athens-Hotels-Athenaeum-InterContinental.h19591.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/84000000/83980000/83976200/83976194/91f4ad27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Guestroom | Premium bedding, down duvets, minibar, in-room safe](https://images.trvl-media.com/lodging/84000000/83980000/83976200/83976194/f45ac045.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily continental breakfast for a fee](https://images.trvl-media.com/lodging/84000000/83980000/83976200/83976194/af3656b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open noon to 8:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/84000000/83980000/83976200/83976194/3891b46a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### UMusic Hotel Madrid [](https://www.expedia.co.uk/Madrid-Hotels-UMusic-Hotel-Madrid.h83976194.Hotel-Information) Madrid Centro 9.4/10 Exceptional (788) "Good hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angel £171 includes taxes & fees 11 Jan - 12 Jan 2026 [](https://www.expedia.co.uk/Madrid-Hotels-UMusic-Hotel-Madrid.h83976194.Hotel-Information) ![2 outdoor pools](https://images.trvl-media.com/lodging/1000000/10000/3800/3780/1d7b7940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach/ocean view](https://images.trvl-media.com/lodging/1000000/10000/3800/3780/91994db3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Club Suite, 1 Bedroom (Mediterranean,Club Level,Larger) | Living room | LCD TV, pay films](https://images.trvl-media.com/lodging/1000000/10000/3800/3780/985836a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cocktail bar](https://images.trvl-media.com/lodging/1000000/10000/3800/3780/b48fd1ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Arts Barcelona [](https://www.expedia.co.uk/Barcelona-Hotels-Hotel-Arts-Barcelona.h3780.Hotel-Information) Sant Martí 9.0/10 Wonderful (1001) "Fabulous hotel with a very friendly staff. I would definitely recommend it and get the city view, it’s fantastic." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bruce £352 includes taxes & fees 5 Jan - 6 Jan 2026 [](https://www.expedia.co.uk/Barcelona-Hotels-Hotel-Arts-Barcelona.h3780.Hotel-Information) ![Couples treatment room(s), sauna, hot tub, steam room](https://images.trvl-media.com/lodging/1000000/20000/17400/17348/792b4779.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom (Iconic) | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/1000000/20000/17400/17348/7c219627.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/20000/17400/17348/w3840h2440x0y3-e37b92aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves lunch and dinner](https://images.trvl-media.com/lodging/1000000/20000/17400/17348/3c511264.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hyatt Barcelona [](https://www.expedia.co.uk/Barcelona-Hotels-Hotel-SOFIA-Barcelona.h17348.Hotel-Information) Les Corts 9.2/10 Wonderful (1479) "Staff members very friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hugo Giovanni £153 includes taxes & fees 23 Jan - 24 Jan 2026 [](https://www.expedia.co.uk/Barcelona-Hotels-Hotel-SOFIA-Barcelona.h17348.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/54400/54350/f937abbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/54400/54350/c9d7c2d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Queen Bed, Terrace (Two Storey) | View from room](https://images.trvl-media.com/lodging/1000000/60000/54400/54350/0f5aada1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/54400/54350/4a3c096b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### InterContinental Lisbon by IHG [](https://www.expedia.co.uk/Lisbon-District-Hotels-InterContinental-Lisbon.h54350.Hotel-Information) Lisbon City Center 9.2/10 Wonderful (1003) "Overall a great experience at this property! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Miguel £165 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Lisbon-District-Hotels-InterContinental-Lisbon.h54350.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/2100/2061/07fc9253.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/2100/2061/58f9e357.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/10000/2100/2061/dd91ed2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Twin Room | Minibar, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/1000000/10000/2100/2061/c80c0a1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Avenida Palace [](https://www.expedia.co.uk/Lisbon-District-Hotels-Avenida-Palace.h2061.Hotel-Information) Lisbon City Center 9.8/10 Exceptional (1003) "Great location and wonderful breakfast" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Robert £210 includes taxes & fees 15 Jan - 16 Jan 2026 [](https://www.expedia.co.uk/Lisbon-District-Hotels-Avenida-Palace.h2061.Hotel-Information) ![Porch](https://images.trvl-media.com/lodging/2000000/1200000/1199100/1199013/3cc9c093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1200000/1199100/1199013/46e0d4a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1200000/1199100/1199013/a737ae9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/2000000/1200000/1199100/1199013/62c7a311.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Puerta América [](https://www.expedia.co.uk/Madrid-Hotels-Hotel-Puerta-America.h1199013.Hotel-Information) Chamartín 8.8/10 Excellent (1003) "Everything was perfect and the hotel is beautiful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Isaias £127 includes taxes & fees 19 Jan - 20 Jan 2026 [](https://www.expedia.co.uk/Madrid-Hotels-Hotel-Puerta-America.h1199013.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/30000/22100/22014/2ce33ea4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, memory-foam beds, minibar](https://images.trvl-media.com/lodging/1000000/30000/22100/22014/df60c6ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/30000/22100/22014/3df12022.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/22100/22014/f2b2726d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Only YOU Hotel Valencia [](https://www.expedia.co.uk/Valencia-Hotels-Only-YOU-Hotel-Valencia.h22014.Hotel-Information) Valencia City Centre 9.8/10 Exceptional (976) "Lovely hotel, great location " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Paul £110 includes taxes & fees 12 Jan - 13 Jan 2026 [](https://www.expedia.co.uk/Valencia-Hotels-Only-YOU-Hotel-Valencia.h22014.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/77000000/76580000/76579100/76579070/8ca5781e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/77000000/76580000/76579100/76579070/d1937ca8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/77000000/76580000/76579100/76579070/w5760h3835x0y5-37c33c06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Terrace | Hypo-allergenic bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/77000000/76580000/76579100/76579070/df051da6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Thompson Madrid, by Hyatt [](https://www.expedia.co.uk/Madrid-Hotels-Thompson-Madrid.h76579070.Hotel-Information) Madrid Centro 9.6/10 Exceptional (315) "Such an amazing hotel, the staff were so nice and the hotel was very clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angelica £244 includes taxes & fees 7 Jan - 8 Jan 2026 [](https://www.expedia.co.uk/Madrid-Hotels-Thompson-Madrid.h76579070.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/1000000/530000/527600/527569/d3746147.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/530000/527600/527569/e81381d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/530000/527600/527569/44c9440a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/530000/527600/527569/51d934b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Electra Palace Athens [](https://www.expedia.co.uk/Athens-Hotels-Electra-Palace-Athens.h527569.Hotel-Information) Athens City Centre 9.6/10 Exceptional (1002) "Was a great hotel and location loved every day" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Paul Rodney £140 includes taxes & fees 13 Jan - 14 Jan 2026 [](https://www.expedia.co.uk/Athens-Hotels-Electra-Palace-Athens.h527569.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Mediterranean-Region-Hotels.s50-0-d844522342175883264.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Mediterranean-Region-Hotels.s50-0-d844522342175883264.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mediterranean Region. ![Barcelona Airport Hotel](https://images.trvl-media.com/lodging/2000000/1440000/1440000/1439964/ab2f831e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Barcelona Airport Hotel Plaza de la Volateria, 3 El Prat de Llobregat £106 17 Jan - 18 Jan 2026 includes taxes & fees 8.6/10 Excellent! (5,162 reviews) [](https://expedia.co.uk/Barcelona-Hotels-Barcelona-Airport-Hotel.h1439964.Hotel-Information) ![Bettoja Hotel Mediterraneo](https://images.trvl-media.com/lodging/1000000/10000/8800/8711/05f1eca2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Bettoja Hotel Mediterraneo Via Cavour 15 Rome RM £163 6 Jan - 7 Jan 2026 includes taxes & fees 8.6/10 Excellent! (995 reviews) [](https://expedia.co.uk/Rome-Hotels-Bettoja-Hotel-Mediterraneo.h8711.Hotel-Information) ![Hotel Emperador](https://images.trvl-media.com/lodging/1000000/10000/1000/915/2f47a159_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Emperador Gran Via 53 Madrid Madrid £130 6 Jan - 7 Jan 2026 includes taxes & fees 9.2/10 Wonderful! (1,912 reviews) [](https://expedia.co.uk/Madrid-Hotels-Hotel-Emperador.h915.Hotel-Information) Still don't see what you're looking for? [See all properties in Mediterranean Region.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=31%2F12%2F2025&endDate=01%2F01%2F2026®ionId=844522342175883264&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=31%2F12%2F2025&endDate=01%2F01%2F2026®ionId=844522342175883264&star=50&star=50&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=31%2F12%2F2025&endDate=01%2F01%2F2026®ionId=844522342175883264&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=31%2F12%2F2025&endDate=01%2F01%2F2026®ionId=844522342175883264&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=31%2F12%2F2025&endDate=01%2F01%2F2026®ionId=844522342175883264&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=31%2F12%2F2025&endDate=01%2F01%2F2026®ionId=844522342175883264&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Mediterranean Region Plan your trip to Mediterranean Region and take advantage of the sights and activities in the area. [See all hotels in Mediterranean Region](https://www.expedia.co.uk/Hotel-Search?startDate=2026-01-13&endDate=2026-01-14&adults=2®ionId=844522342175883264) ![Mazarrón, Spain](https://images.trvl-media.com/place/553248633936349954/597750c4-7c4e-4a36-b33c-904705e647c4.jpg?impolicy=fcrop&w=900&h=599&p=1&q=high) ## Top Mediterranean Region Hotel Reviews ![Akra Antalya](https://images.trvl-media.com/lodging/1000000/30000/21700/21663/1add5596_y.jpg) ### Akra Antalya 10/10 Excellent "Clean and very helpful staff." [](https://expedia.co.uk/Antalya-Hotels-Akra-Hotel.h21663.Hotel-Information) ![Nobu Hotel Barcelona](https://images.trvl-media.com/lodging/40000000/39070000/39067400/39067368/de597f46_y.jpg) ### Nobu Hotel Barcelona 10/10 Excellent "Nobu Hotel is beautiful, comfortable, and the staff were very professional and friendly - in multiple languages! It was a restful and convenient place to stay in Barcelona. " [](https://expedia.co.uk/Barcelona-Hotels-Nobu-Hotel-Barcelona.h39067368.Hotel-Information) ## Find out more about Mediterranean Region