Title: Mediterranean Region Travel Guide: Best of Mediterranean Region, Travel 2025 | Expedia.co.uk [Hotels in Mediterranean Region](https://expedia.co.uk/Mediterranean-Region-Hotels.d844522342175883264.Travel-Guide-Hotels)[Holiday Rentals in Mediterranean Region](https://expedia.co.uk/Mediterranean-Region-Holiday-Rentals.d844522342175883264.Travel-Guide-HolidayRentals)[Flights to Mediterranean Region](https://expedia.co.uk/Cheap-Flights-To-Mediterranean-Region.d844522342175883264.Travel-Guide-Flights)[Mediterranean Region Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mediterranean-Region.d844522342175883264.Car-Hire-Guide)[Mediterranean Region Holidays](https://expedia.co.uk/Mediterranean-Region.d844522342175883264.Holidays-City-Breaks) # Mediterranean Region Travel Guide ## Tourist Guide ![Mediterranean Region](https://mediaim.expedia.com/destination/9/abc24df6f2e3266327aa8b559e87e79a.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Roman Forum showing heritage architecture and building ruins](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/20000/20269-Roman-Forum.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Roman Forum featuring heritage architecture and building ruins](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/20000/20271-Roman-Forum.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![St. Peter\'s Square featuring a square or plaza and heritage architecture](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/20000/20276-Piazza-San-Pietro-St-Peters-Square.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Roman Forum showing night scenes, a church or cathedral and a monument](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/20000/20267-Roman-Forum.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Mediterranean Region Where to stay Things to do ### Where to stay in Mediterranean Region ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/146000/146623-Via-Del-Corso.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Rome City Centre 4.5/5(1,362 area reviews) Trevi Fountain and Piazza Navona are a few top attractions in Rome City Centre. Hop around the city on the metro at Venezia Tram Stop or Arenula-Cairoli Tram Station and check out the area's fascinating museums, stunning cathedral and stunning river views. [](https://expedia.co.uk/Rome-Rome-City-Centre.dx553248633938945217) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/349000/349161-Puerta-Del-Sol.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Madrid Centro 4.5/5(745 area reviews) Known for its fascinating museums and acclaimed art galleries, there's plenty to explore in Madrid Centro. Check out top attractions like Puerta del Sol and Plaza Mayor, and jump on the metro at Sol Station or Gran Via Station to see more of the city. [](https://expedia.co.uk/Madrid-Madrid-Centro.dx553248631822337314) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/348000/348228-Basilica-De-Santa-Maria-Del-Mar.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Downtown Barcelona Known for its fascinating museums, stunning cathedral and popular shops, there's plenty to explore in Downtown Barcelona. Top attractions like La Rambla and Plaça de Catalunya are major draws. Catch the metro at Liceu Station or Jaume I Station to see more of the city. [](https://expedia.co.uk/Barcelona-Downtown-Barcelona.dx6220952) ![Lisbon showing château or palace, views and a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/53000/53919-Castle-Of-Sao-Jorge.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Lisbon City Center Avenida da Liberdade and Rossio Square are top sights in Lisbon City Center, and you should be sure to explore the popular shops. Hop aboard the metro at Saldanha Station or Sao Sebastiao Station to see more sights in the area. [](https://expedia.co.uk/Lisbon-District-Lisbon-City-Center.dx6145189) ![Rome Historic Centre which includes a fountain, a square or plaza and a statue or sculpture](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/146000/146761-Rome-City-Centre.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Rome Historic Centre Known for its fascinating museums, stunning cathedral and charming cafes, there's plenty to explore in Rome Historic Centre. Top attractions like Colosseum and Trevi Fountain are major draws. Catch the metro at Venezia Tram Stop or Colosseo Station to see more of the city. [](https://expedia.co.uk/Rome-Rome-Historic-Centre.dx6200441) ![Academy of Athens showing heritage architecture, heritage elements and an administrative building](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/42000/42106-Academy-Of-Athens.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Athens City Centre 4.5/5(483 area reviews) Known for its fascinating museums, charming cafes and popular shops, there's plenty to explore in Athens City Centre. Top attractions like Syntagma Square and Acropolis are major draws. Catch the metro at Panepistimio Station or Syntagma Station to see more of the city. [](https://expedia.co.uk/Athens-Athens-City-Centre.dx6200220) - Top hotels in Mediterranean Region - Top Holiday Rentals in Mediterranean Region ![Barcelona Airport Hotel](https://images.trvl-media.com/lodging/2000000/1440000/1440000/1439964/ab2f831e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Barcelona Airport Hotel Plaza de la Volateria, 3, Poligono Mas Blau, El Prat de Llobregat Fully refundableReserve now, pay when you stay £124 31 Oct - 1 Nov includes taxes & fees Stay at this 4-star business-friendly hotel in El Prat de Llobregat. Enjoy free Wi-Fi, an outdoor pool and 2 restaurants. Our guests praise the breakfast and ... 8.6/10 Excellent! (4,982 reviews) "The blackout shades are the best we’ve ever had. The AC kept the room plenty cool Staff was very helpful The breakfast buffet was excellent Close to the airport" Reviewed on 29 Sept 2025 [](https://expedia.co.uk/Hotel-Search?startDate=31%2F10%2F2025&endDate=01%2F11%2F2025&selected=1439964&PinnedHotelID=1439964&HadPinnedHotel=true®ionId=844522342175883264) ![Grand Hyatt Athens](https://images.trvl-media.com/lodging/1000000/30000/21100/21031/dbfe795f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Grand Hyatt Athens 115, Syngrou Avenue, Athens, Attica £125 26 Oct - 27 Oct includes taxes & fees Stay at this 5-star luxury hotel in Athens. Enjoy free Wi-Fi, an outdoor pool and a full-service spa. Our guests praise the breakfast and the pool in their reviews. ... 8.6/10 Excellent! (864 reviews) "Staff fine dining atmosphere" Reviewed on 1 Oct 2025 [](https://expedia.co.uk/Hotel-Search?startDate=26%2F10%2F2025&endDate=27%2F10%2F2025&selected=21031&PinnedHotelID=21031&HadPinnedHotel=true®ionId=844522342175883264) ![Radisson Blu Hotel](https://images.trvl-media.com/lodging/1000000/530000/524600/524550/907de448_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Radisson Blu Hotel Avenida Marechal Craveiro Lopes, 390, Campo Grande, Lisbon £84 2 Nov - 3 Nov includes taxes & fees Stay at this 4-star hotel in Lisbon. Enjoy free Wi-Fi, breakfast (surcharge) and 24-hour room service. Our guests praise the helpful staff and the clean rooms ... 8.2/10 Very Good! (2,043 reviews) "Clean!" Reviewed on 4 Oct 2025 [](https://expedia.co.uk/Hotel-Search?startDate=02%2F11%2F2025&endDate=03%2F11%2F2025&selected=524550&PinnedHotelID=524550&HadPinnedHotel=true®ionId=844522342175883264) [See all 786,714 properties in Mediterranean Region](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=07%2F10%2F2025&endDate=08%2F10%2F2025®ionId=844522342175883264) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Gran View Apartments](https://images.trvl-media.com/lodging/64000000/63900000/63897000/63896948/e4b49251_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Gran View Apartments C/ Gran Vía 48, Madrid, Madrid Stay at this 4-star business-friendly aparthotel in Madrid. Enjoy free Wi-Fi, an outdoor pool and a rooftop terrace. Our guests praise the helpful staff and ... 9/10 Wonderful! (1,279 reviews) Family from Ireland. "Excellent location. Roof top pool amazing . Staff so helpful. Excellent location to explore the city of Madrid" Reviewed on 3 Oct 2025 [](https://expedia.co.uk/Madrid-Hotels-Gran-View-Apartments.h63896948.Hotel-Information) ![Fabulous Village](https://images.trvl-media.com/lodging/5000000/4170000/4163300/4163290/c5a3b3c1_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Fabulous Village Via Di Malafede 225, Rome, RM Stay at this family-friendly campsite in Rome. Enjoy free parking, an outdoor pool and 2 hot tubs. Our guests praise the helpful staff in their reviews. Popular ... 8.2/10 Very Good! (1,548 reviews) "This place was amazing went with 3 kids and they had a blast" Reviewed on 30 Sept 2025 [](https://expedia.co.uk/Rome-Hotels-Fabulous-Village.h4163290.Hotel-Information) ![Hesperia Sant Joan](https://images.trvl-media.com/lodging/1000000/570000/565800/565724/w6016h4009x0y0-d75b90db_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hesperia Sant Joan Josep Trueta 2 San Joan Despi, Sant Joan Despi Stay at this 3-star eco-certified aparthotel in Sant Joan Despi. Enjoy free Wi-Fi, an outdoor pool and a fitness centre. Popular attractions Camp Nou and Passeig ... 7.8/10 Good! (1,740 reviews) "Cleannnn" Reviewed on 1 Oct 2025 [](https://expedia.co.uk/Barcelona-Hotels-Hesperia-Sant-Joan.h565724.Hotel-Information) [See all properties in Mediterranean Region](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=844522342175883264&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Mediterranean Region hotel availability [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=844522342175883264&startDate=2025-10-06&endDate=2025-10-07) [Tonight](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=844522342175883264&startDate=2025-10-06&endDate=2025-10-07) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=844522342175883264&startDate=2025-10-06&endDate=2025-10-07) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=844522342175883264&startDate=2025-10-06&endDate=2025-10-07)[6 Oct - 7 Oct](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=844522342175883264&startDate=2025-10-06&endDate=2025-10-07) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=844522342175883264&startDate=2025-10-07&endDate=2025-10-08) [Tomorrow night](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=844522342175883264&startDate=2025-10-07&endDate=2025-10-08) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=844522342175883264&startDate=2025-10-07&endDate=2025-10-08) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=844522342175883264&startDate=2025-10-07&endDate=2025-10-08)[7 Oct - 8 Oct](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=844522342175883264&startDate=2025-10-07&endDate=2025-10-08) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=844522342175883264&startDate=10%2F10%2F2025&endDate=12%2F10%2F2025) [This weekend](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=844522342175883264&startDate=10%2F10%2F2025&endDate=12%2F10%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=844522342175883264&startDate=10%2F10%2F2025&endDate=12%2F10%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=844522342175883264&startDate=10%2F10%2F2025&endDate=12%2F10%2F2025)[10 Oct - 12 Oct](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=844522342175883264&startDate=10%2F10%2F2025&endDate=12%2F10%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=844522342175883264&startDate=17%2F10%2F2025&endDate=19%2F10%2F2025) [Next weekend](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=844522342175883264&startDate=17%2F10%2F2025&endDate=19%2F10%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=844522342175883264&startDate=17%2F10%2F2025&endDate=19%2F10%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=844522342175883264&startDate=17%2F10%2F2025&endDate=19%2F10%2F2025)[17 Oct - 19 Oct](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=844522342175883264&startDate=17%2F10%2F2025&endDate=19%2F10%2F2025) ### Popular places to visit ![Italy showing building ruins, a city and heritage architecture](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/20000/20302-Colosseum.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Colosseum One of Rome's most famous landmarks, and one of the world's most notable monuments, no visitor to Rome should miss the opportunity to visit this iconic structure. [](https://expedia.co.uk/Colosseum-Rome-City-Centre.d6046257.Attraction) ![Sagrada Familia featuring religious aspects, heritage architecture and a church or cathedral](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/52000/52304-Barcelona.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Sagrada Familia Gaudí’s basilica in the center of Barcelona is an architectural marvel and offers views across the city from eight towering spires. [](https://expedia.co.uk/Sagrada-Familia-Eixample.d6066943.Attraction) ![Gran Via which includes heritage architecture, night scenes and landscape views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/26000/26515-Madrid.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Gran Via Madrid’s famous shopping strip has boutiques and international brands, an exciting nightlife and an impressive display of early 20th-century architecture. [](https://expedia.co.uk/Gran-Via-Madrid-Centro.d6221074.Attraction) ![Trevi Fountain showing heritage elements, a fountain and heritage architecture](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/20000/20309-Trevi-Fountain.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Trevi Fountain Rome is a city abundant in world-class water features, but none more stunning, or more famous, than the Trevi Fountain. [](https://expedia.co.uk/Trevi-Fountain-Rome-City-Centre.d6341167.Attraction) ![Port of Piraeus](https://mediaim.expedia.com/destination/1/bf1c2b7e5a250abc58a0cbe2364312b8.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Port of Piraeus Explore the waterfront in Athens with a trip to Port of Piraeus. Discover the top-notch restaurants and fascinating museums in this walkable area. [](https://expedia.co.uk/Port-Of-Piraeus-Athens.d6173316.Attraction) ![La Rambla](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/52000/52589-Las-Ramblas.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### La Rambla These lively pedestrian streets in the heart of Barcelona are filled with flower stalls, tapas restaurants and street performers. [](https://expedia.co.uk/La-Rambla-Downtown-Barcelona.d6066981.Attraction) - Places of interest - [Duoro River](https://expedia.co.uk/Duoro-River-Europe.d553248621532486759.Attraction) - [Gulf of Lion](https://expedia.co.uk/Gulf-Of-Lion-Europe.d3000655073.Attraction) - [Paul VI Audience Hall](https://expedia.co.uk/Paul-VI-Audience-Hall-Vatican.d6116036.Attraction) - [Sierra de la Culebra](https://expedia.co.uk/Sierra-De-La-Culebra-Europe.d553248634096158884.Attraction) - [Perejil Island](https://expedia.co.uk/Perejil-Island-Africa.d553248635961260098.Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)