Title: Mediterranean Region Holidays 2026 from £221 | Expedia.co.uk [Mediterranean Region Travel Guide](https://expedia.co.uk/Mediterranean-Region.dx844522342175883264)[Hotels in Mediterranean Region](https://expedia.co.uk/Mediterranean-Region-Hotels.d844522342175883264.Travel-Guide-Hotels)[Holiday Rentals in Mediterranean Region](https://expedia.co.uk/Mediterranean-Region-Holiday-Rentals.d844522342175883264.Travel-Guide-HolidayRentals)[Flights to Mediterranean Region](https://expedia.co.uk/Cheap-Flights-To-Mediterranean-Region.d844522342175883264.Travel-Guide-Flights)[Mediterranean Region Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mediterranean-Region.d844522342175883264.Car-Hire-Guide) ![](https://images.trvl-media.com/place/6060408/422dd3ce-d69d-46d2-8d8f-0d4c55a18743.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Mediterranean Region Holidays from £191 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to £335 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Packages with flights are ATOL protected ## Top Mediterranean Region Flight + Hotel Deals Price found within the past 48 hours. Click for updated prices. ![Hotel Fiori](https://images.trvl-media.com/lodging/1000000/900000/891100/891084/449d257c_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Fiori Rome City Centre £191 per person 4 Feb - 7 Feb found 24 hours ago Return flight included London (STN) to Rome (FCO) 9.2/10 Wonderful! (22 reviews) The breakfast was very basic with some crossionts, boiled egg, and few slices of cuts. The rooms are super basic but clean The location is however exceptional, just 15 minutes walk to Colloseum Reviewed on 28 Oct 2025 ![Hotel Delle Civette](https://images.trvl-media.com/lodging/101000000/100970000/100969400/100969343/098779c1_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Delle Civette Nomentano £315 per person 28 Feb - 4 Mar found 1 hour ago Return flight included London (LCY) to Rome (FCO) 9.6/10 Exceptional! (267 reviews) We are Canadians who stayed 2 weeks at this hotel and so happy we did. This hotel offered amazing staff, great atmosphere, fantastic cappuccinos and espresso’s. The breakfast had an abundance of selection. Eggs, bacon the usual and of course Italian style. We would share a bottle of wine on the terrace at night and enjoy the view. We were there Nov 29 until Dec 13\. We would say the best time to visit Italy. We selected this hotel because it was away from the city center and more into the local area. Things were much cheaper especially groceries at PAM local. Favorite restaurant near by was I Belcastro about 10 mins away and the best margarita pizza you will ever taste. The bus is very close and the number of bus that gets you everywhere is bus 62 or 60\. Get a bus pass to save money at the local station. But if you want to burn off calories and take a great walk, we waked about 3 to 5km a day. You won’t even notice that you walked that far because it’s a pleasant walk. So try both. If your like us and don’t want to stay in hotels in the heart of town where a billion people are than choose Hotel Delle Civette. Reviewed on 14 Dec 2025 ![Albergo Etico Roma](https://images.trvl-media.com/lodging/34000000/33130000/33120500/33120475/6b9ee00e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Albergo Etico Roma Flaminio £221 per person 4 Feb - 7 Feb found 24 hours ago Return flight included London (STN) to Rome (FCO) 9.6/10 Exceptional! (335 reviews) Great place to stay Reviewed on 1 Dec 2025 ![Charme Spagna Boutique Hotel](https://images.trvl-media.com/lodging/19000000/18300000/18294700/18294667/57c4458b_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Charme Spagna Boutique Hotel Rome City Centre £279 per person 4 Feb - 7 Feb found 24 hours ago Return flight included London (STN) to Rome (FCO) 9.2/10 Wonderful! (208 reviews) The staff was so lovely and polite and really helpful, hotel was clean and everything you needed. Hotel was brilliant location, only thing I would say is taxis and Ubers are a lot cheaper than the transfer service to airport that the hotel offered, but would defo recommend Reviewed on 4 Dec 2025 ![Smart Guesthouse](https://images.trvl-media.com/lodging/92000000/91080000/91079900/91079832/87b39f3b_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Smart Guesthouse Rome City Centre Save 100% on your flight £233 per person 9 Mar - 12 Mar found 21 hours ago Return flight included Manchester (MAN) to Rome (FCO) 9.6/10 Exceptional! (76 reviews) Great location because of how close it is to the train station, stay was very pleasant. The hotel was super communicative. Would recommend! Reviewed on 19 Nov 2025 ## Where to stay in Mediterranean Region Find the best Mediterranean Region areas and neighborhoods for the activities you enjoy most. [Learn more about Mediterranean Region](https://expedia.co.uk/Mediterranean-Region.dx844522342175883264) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/146000/146623-Via-Del-Corso.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Rome City Centre 4.5/5(1,362 area reviews) Trevi Fountain and Piazza Navona are a few top attractions in Rome City Centre. Hop around the city on the metro at Venezia Tram Stop or Arenula-Cairoli Tram Station and check out the area's fascinating museums, stunning cathedral and stunning river views. [Find hotels in Rome City Centre](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Dest.PKG.Neighborhoods®ionId=553248633938945217) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/349000/349161-Puerta-Del-Sol.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Madrid Centro 4.5/5(745 area reviews) Known for its fascinating museums and acclaimed art galleries, there's plenty to explore in Madrid Centro. Check out top attractions like Gran Via and Puerta del Sol, and jump on the metro at Sol Station or Gran Via Station to see more of the city. [Find hotels in Madrid Centro](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Dest.PKG.Neighborhoods®ionId=553248631822337314) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/348000/348228-Basilica-De-Santa-Maria-Del-Mar.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Downtown Barcelona Known for its fascinating museums, stunning cathedral and popular shops, there's plenty to explore in Downtown Barcelona. Top attractions like La Rambla and Plaça de Catalunya are major draws. Catch the metro at Liceu Station or Jaume I Station to see more of the city. [Find hotels in Downtown Barcelona](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Dest.PKG.Neighborhoods®ionId=6220952) ![Lisbon showing château or palace, views and a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/53000/53919-Castle-Of-Sao-Jorge.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Lisbon City Center Rossio Square and Saldanha Square are top sights in Lisbon City Center, and you should be sure to explore the popular shops. Hop aboard the metro at Saldanha Station or Sao Sebastiao Station to see more sights in the area. [Find hotels in Lisbon City Center](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Dest.PKG.Neighborhoods®ionId=6145189) ![Rome Historic Centre which includes a fountain, a square or plaza and a statue or sculpture](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/146000/146761-Rome-City-Centre.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Rome Historic Centre Visit the center of Italy’s capital and enjoy traditional Italian food. Relax in old bars and see some of the city’s famous historic sites. [Find hotels in Rome Historic Centre](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Dest.PKG.Neighborhoods®ionId=6200441) ## Top hotels in Mediterranean Region ![Barcelona Airport Hotel](https://images.trvl-media.com/lodging/2000000/1440000/1440000/1439964/ab2f831e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Barcelona Airport Hotel Plaza de la Volateria, 3 El Prat de Llobregat Fully refundableReserve now, pay when you stay £115 9 Jan - 10 Jan 2026 includes taxes & fees 8.6/10 Excellent! (5,142 reviews) . Reviewed on 10 Dec 2025 [](https://expedia.co.uk/Hotel-Search?startDate=09%2F01%2F2026&endDate=10%2F01%2F2026&selected=1439964&PinnedHotelID=1439964&HadPinnedHotel=true®ionId=844522342175883264) ![Hotel Riu Plaza España](https://images.trvl-media.com/lodging/30000000/29350000/29345500/29345493/42fcab3f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Riu Plaza España C/ Gran Via, 84 Madrid Fully refundableReserve now, pay when you stay £133 18 Dec - 19 Dec includes taxes & fees 9.2/10 Wonderful! (4,522 reviews) Functional and nice rooms although no view, nice rooftop and great breakfast. Reviewed on 11 Dec 2025 [](https://expedia.co.uk/Hotel-Search?startDate=18%2F12%2F2025&endDate=19%2F12%2F2025&selected=29345493&PinnedHotelID=29345493&HadPinnedHotel=true®ionId=844522342175883264) ![Hotel Emperador](https://images.trvl-media.com/lodging/1000000/10000/1000/915/2f47a159_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Emperador Gran Via 53 Madrid Madrid Fully refundableReserve now, pay when you stay £148 17 Dec - 18 Dec includes taxes & fees 9.2/10 Wonderful! (1,899 reviews) Buenas habitaciones Buena localización Roof top buena vista Desayuno Reviewed on 13 Dec 2025 [](https://expedia.co.uk/Hotel-Search?startDate=17%2F12%2F2025&endDate=18%2F12%2F2025&selected=915&PinnedHotelID=915&HadPinnedHotel=true®ionId=844522342175883264) [See all 777,853 properties in Mediterranean Region](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=16%2F12%2F2025&endDate=17%2F12%2F2025®ionId=844522342175883264) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holidays](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![Holiday in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ### Popular places to visit ![Italy showing building ruins, a city and heritage architecture](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/20000/20302-Colosseum.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Colosseum 4.5/5(1,980 reviews) One of Rome's most famous landmarks, and one of the world's most notable monuments, no visitor to Rome should miss the opportunity to visit this iconic structure. [](https://expedia.co.uk/Colosseum-Rome-City-Centre.d6046257.Attraction) ![Sagrada Familia featuring religious aspects, heritage architecture and a church or cathedral](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/52000/52304-Barcelona.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Sagrada Familia 4.5/5(1,450 reviews) Gaudí’s basilica in the center of Barcelona is an architectural marvel and offers views across the city from eight towering spires. [](https://expedia.co.uk/Sagrada-Familia-Eixample.d6066943.Attraction) ![Gran Via which includes heritage architecture, night scenes and landscape views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/26000/26515-Madrid.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Gran Via 4/5(413 reviews) Madrid’s famous shopping strip has boutiques and international brands, an exciting nightlife and an impressive display of early 20th-century architecture. [](https://expedia.co.uk/Gran-Via-Madrid-Centro.d6221074.Attraction) ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app