Title: Mediterranean Region Holidays 2026 from £438 | Expedia.co.uk [Mediterranean Region Travel Guide](https://expedia.co.uk/Mediterranean-Region.dx844522342175883264)[Hotels in Mediterranean Region](https://expedia.co.uk/Mediterranean-Region-Hotels.d844522342175883264.Travel-Guide-Hotels)[Holiday Rentals in Mediterranean Region](https://expedia.co.uk/Mediterranean-Region-Holiday-Rentals.d844522342175883264.Travel-Guide-HolidayRentals)[Flights to Mediterranean Region](https://expedia.co.uk/Cheap-Flights-To-Mediterranean-Region.d844522342175883264.Travel-Guide-Flights)[Mediterranean Region Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mediterranean-Region.d844522342175883264.Car-Hire-Guide) ![](https://images.trvl-media.com/place/844522342175883264/0ff12a1f-4be6-4129-b1d3-12d8b49d171a.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Mediterranean Region Holidays from £438 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to £335 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Packages with flights are ATOL protected ## Top Mediterranean Region Flight + Hotel Deals Price found within the past 48 hours. Click for updated prices. ![Relais de la Poste](https://images.trvl-media.com/lodging/39000000/38910000/38902300/38902220/c47eaf80_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Relais de la Poste Rome City Centre £438 per person 2 May - 5 May found 15 hours ago Return flight included London (LON) to Rome (FCO) 9.2/10 Wonderful! (639 reviews) Great location in the heart of Rome. Most major attractions are within walking distance — about 25 minutes to the Vatican, Trevi Fountain, and Pantheon, 10 minutes to the Spanish Steps, and around 35 minutes to the Colosseum (or 15 minutes by metro). The staff were very friendly and welcoming, and our room was cleaned and the bed made every day. The hotel is clean, well presented, and located on the second floor. The shower was spacious and we appreciated the free water dispenser with reusable bottles provided. Breakfast is simple but enough to start the day. The only minor issues were that the ground floor buzzer didn’t seem to work on arrival, and the underside of the decorative bed runner had a stain. Overall, a comfortable stay in a very convenient location. Reviewed on 12 Mar 2026 ![Hotel Delle Civette](https://images.trvl-media.com/lodging/101000000/100970000/100969400/100969343/205f358e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Delle Civette Nomentano £543 per person 9 May - 14 May found 7 hours ago Return flight included Manchester (MAN) to Rome (FCO) 9.6/10 Exceptional! (287 reviews) Courteous and helpful staff. Clean, great amenities Reviewed on 8 Feb 2026 ![Albergo Etico Roma](https://images.trvl-media.com/lodging/34000000/33130000/33120500/33120475/0a76f398_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Albergo Etico Roma Flaminio £452 per person 29 Apr - 2 May found 1 day ago Return flight included London (LTN) to Rome (FCO) 9.6/10 Exceptional! (353 reviews) Wonderful bijou oasis! Exceptionally friendly and helpful staff made for a memorable and relaxing stay. Reviewed on 11 Mar 2026 ![The Retreat Collection at 1 Hotel & Homes South Beach](https://images.trvl-media.com/lodging/13000000/12320000/12316600/12316590/e518a34f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Retreat Collection at 1 Hotel & Homes South Beach South Beach £10,348 per person 19 Apr - 26 Apr found 11 hours ago Return flight included London (LHR) to Miami (MIA) 8/10 Very Good! (1 review) ## Where to stay in Mediterranean Region Find the best Mediterranean Region areas and neighborhoods for the activities you enjoy most. [Learn more about Mediterranean Region](https://expedia.co.uk/Mediterranean-Region.dx844522342175883264) ![Via del Corso which includes heritage architecture, heritage elements and street scenes](https://images.trvl-media.com/place/6147046/23c2bc21-bb33-4778-b64d-bbfa58503b1c.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Rome City Centre 4.5/5(1,362 area reviews) Trevi Fountain and Piazza Navona are a few top attractions in Rome City Centre. Hop around the city on the metro at Venezia Tram Stop or Arenula-Cairoli Tram Station and check out the area's fascinating museums, stunning cathedral and stunning river views. [Find hotels in Rome City Centre](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Dest.PKG.Neighborhoods®ionId=553248633938945217) ![Puerta del Sol showing street scenes, a sunset and a city](https://images.trvl-media.com/place/6282935/7c7b450a-044c-40c0-bf69-2c376f7bb61d.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Madrid Centro 4.5/5(745 area reviews) Known for its fascinating museums and acclaimed art galleries, there's plenty to explore in Madrid Centro. Check out top attractions like Puerta del Sol and Gran Via, and jump on the metro at Sol Station or Gran Via Station to see more of the city. [Find hotels in Madrid Centro](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Dest.PKG.Neighborhoods®ionId=553248631822337314) ![Basilica de Santa Maria del Mar showing a church or cathedral and heritage architecture](https://images.trvl-media.com/place/6066991/c3c69d6e-c998-4f36-ad18-3e65173208c0.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Downtown Barcelona Known for its fascinating museums, stunning cathedral and popular shops, there's plenty to explore in Downtown Barcelona. Top attractions like La Rambla and Plaça de Catalunya are major draws. Catch the metro at Liceu Station or Jaume I Station to see more of the city. [Find hotels in Downtown Barcelona](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Dest.PKG.Neighborhoods®ionId=6220952) ![Rome Historic Centre which includes a fountain, a square or plaza and a statue or sculpture](https://images.trvl-media.com/place/6200441/57c34773-acbf-4b05-b5e7-9b3e692babe1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Rome Historic Centre Visit the center of Italy’s capital and enjoy traditional Italian food. Relax in old bars and see some of the city’s famous historic sites. [Find hotels in Rome Historic Centre](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Dest.PKG.Neighborhoods®ionId=6200441) ![Lisbon showing château or palace, views and a city](https://images.trvl-media.com/place/501492/c9b7368e-ee2a-4663-bda0-fb43471ba65b.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Lisbon City Center Avenida da Liberdade and Rossio Square are top sights in Lisbon City Center, and you should be sure to explore the popular shops. Hop aboard the metro at Saldanha Station or Sao Sebastiao Station to see more sights in the area. [Find hotels in Lisbon City Center](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Dest.PKG.Neighborhoods®ionId=6145189) ## Top hotels in Mediterranean Region ![Barcelona Airport Hotel](https://images.trvl-media.com/lodging/2000000/1440000/1440000/1439964/c4a7aa04_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Barcelona Airport Hotel Plaza de la Volateria, 3 El Prat de Llobregat Fully refundableReserve now, pay when you stay £121 29 Mar - 30 Mar includes taxes & fees 8.8/10 Excellent! (5,138 reviews) Everything was wonderful, the staff were very friendly and the food was amazing Reviewed on 15 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=29%2F03%2F2026&endDate=30%2F03%2F2026&selected=1439964&PinnedHotelID=1439964&HadPinnedHotel=true®ionId=844522342175883264) ![Hotel Quirinale](https://images.trvl-media.com/lodging/1000000/10000/1100/1058/1c2ed679_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Quirinale Via Nazionale 7 Rome RM Fully refundableReserve now, pay when you stay £193 17 Mar - 18 Mar includes taxes & fees 8.6/10 Excellent! (1,951 reviews) Everything was amazing here. The staff were kind and considerate, the breakfast was excellent and the location was prime! Reviewed on 15 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=17%2F03%2F2026&endDate=18%2F03%2F2026&selected=1058&PinnedHotelID=1058&HadPinnedHotel=true®ionId=844522342175883264) ![Ruby Giulia Hotel Rome](https://images.trvl-media.com/lodging/115000000/114940000/114933100/114933055/960b9e99_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Ruby Giulia Hotel Rome Via Agostino Depretis 45 Rome RM Fully refundableReserve now, pay when you stay £183 19 Mar - 20 Mar includes taxes & fees 9.8/10 Exceptional! (50 reviews) This hotel was amazing. They thought of everything with an amazing bar, great staff who were very helpful and great location. Would 100% book again! Reviewed on 15 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=19%2F03%2F2026&endDate=20%2F03%2F2026&selected=114933055&PinnedHotelID=114933055&HadPinnedHotel=true®ionId=844522342175883264) [See all 778,539 properties in Mediterranean Region](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=17%2F03%2F2026&endDate=18%2F03%2F2026®ionId=844522342175883264) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holidays](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![Holiday in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ### Popular places to visit ![Italy showing building ruins, a city and heritage architecture](https://images.trvl-media.com/place/6046257/dfc1097b-fb0b-4d2f-96f5-15d86e72f134.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Colosseum One of Rome's most famous landmarks, and one of the world's most notable monuments, no visitor to Rome should miss the opportunity to visit this iconic structure. [](https://expedia.co.uk/Colosseum-Rome-City-Centre.d6046257.Attraction) ![Sagrada Familia featuring religious aspects, heritage architecture and a church or cathedral](https://images.trvl-media.com/place/6066943/0a7bcc1b-ddfb-447c-acac-8c6cf3635dd2.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Sagrada Familia Gaudí’s basilica in the center of Barcelona is an architectural marvel and offers views across the city from eight towering spires. [](https://expedia.co.uk/Sagrada-Familia-Eixample.d6066943.Attraction) ![Gran Via which includes heritage architecture, night scenes and landscape views](https://images.trvl-media.com/place/6221074/3c4d20dd-d984-4ef4-9f07-d7e411b8f3bb.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Gran Via Madrid’s famous shopping strip has boutiques and international brands, an exciting nightlife and an impressive display of early 20th-century architecture. [](https://expedia.co.uk/Gran-Via-Madrid-Centro.d6221074.Attraction) ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app