Are there any 5-star all-inclusive resorts in Destin?

Our handy filters are the best way to search for exactly what you want. Select "All inclusive" and "5-star" to show the most luxurious hotels in Destin where your accommodation, meals, activities and entertainment are included in the upfront price. At these stays, your trip is absolute indulgence from the moment you arrive.

What are the top 5-star spa hotels in Destin?

The Henderson Beach Resort & Spa combines upmarket accommodation with decadent wellness treatments and experiences. Choose from a menu of massages, facials and more at this sought-after 5-star spa stay in Destin.

Does Destin have any 5-star family resorts?

Spoil the kids with a stay that pairs fun with luxury at The Henderson Beach Resort & Spa . This 5-star property in Destin features conveniences and services that satisfy the needs of families, ensuring that both adults and youngsters have an unforgettable stay.

Are there any 5-star holiday rentals in Destin?

You won't find any 5-star holiday rentals in Destin on our site, but there are a range of other highly rated options worth checking out. Browse our holiday rentals in Destin to discover the perfect place for your getaway.

Are there any 5-star hotels in downtown Destin?

Experience downtown Destin from The Henderson Beach Resort & Spa . Book this 5-star hotel and enjoy easy access to some top things to do and see.

The 10 Best 5 Star Hotels in Destin - 2026 Updated Prices

A wooden pier extending into calm waters at sunset, with a thatched-roof structure at the end.

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Our top choices for Destin 5-star hotels

The Henderson Beach Resort & Spa

Crystal Beach

Jose Manuel

includes taxes & fees

22 Jul - 23 Jul

House, 6 Bedrooms, Ocean View, Beachfront | Aerial view

Capitano 7 Bedroom Holiday Home by Five Star Properties

Destin

House, 6 Bedrooms, Ocean View, Beachfront | Front of property

Palazzo del Mar 11 Bedroom Holiday Home by Five Star Properties

Crystal Beach

Palazzo del Mar by Five Star Properties

Crystal Beach

House, 6 Bedrooms, Ocean View, Beachfront | 7 bedrooms

Millenia 7 Bedroom Holiday Home by Five Star Properties

Destin

House, 6 Bedrooms, Ocean View, Sea Facing | Aerial view

Stranded on a Sandbar 8 Bedroom Holiday Home by Five Star Properties

Frangista Beach

House, 4 Bedrooms, Ocean View, Sea Facing | Exterior

Vista del Mare 4 Bedroom Holiday Home by Five Star Properties

Destin

Modern Paradise by Five Star Properties

Destin

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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Destin.

The Island Resort at Fort Walton Beach

Miracle Strip Parkway Southeast, 1500 Fort Walton Beach FL

£265

22 Jul - 23 Jul

includes taxes & fees

8.2/10 Very good! (3,351 reviews)

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Pool Spa Hot tub Breakfast included Waterpark

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Destin

Sugar-white beaches and emerald waters make this Gulf Coast paradise perfect for snorkelling, dolphin cruises, and fresh seafood dining. Venture beyond the sand to explore Henderson Beach State Park's nature trails or book a deep-sea fishing charter where captains know exactly where the big ones hide.

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A coastal town with a beach, a marina, and a sunset over the ocean.