Compare and book 5 Star hotels in Destin, Florida

Most hotels are fully refundable. Because flexibility matters.

Save an average of 15% on thousands of hotels with Expedia Rewards

Search over 2.9 million properties and 550 airlines worldwide

Top Destin 5 Star Hotels

Exterior
The Henderson Beach Resort & Spa
5.0 star property
9.2 out of 10, Wonderful, (1001)
"Exclusive. Quiet and away from the mainstream. Easy access and reliable service and staff. "
The price is £358
per night
12 May - 13 May
The Henderson Beach Resort & Spa
Beach nearby
Claire De Lune Beach Cottage
5.0 star property
Claire De Lune Beach Cottage
Property grounds
Sungazer Chateau
5.0 star property
Sungazer Chateau
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Beach nearby
Casa Bao
5.0 star property
Casa Bao
House, Multiple Beds, Pool Access, Pool View | Living area | TV
Destin Breeze
5.0 star property
Destin Breeze
House, Multiple Beds, Patio, Garden View | View from room
Driftwood Townhomes #16
5.0 star property
Driftwood Townhomes #16
Beach nearby
Low Cay
5.0 star property
Low Cay
House, 6 Bedrooms, Ocean View, Beachfront | Outdoor pool
Palazzo del Mar 11 Bedroom Holiday Home by Five Star Properties
5.0 star property
Palazzo del Mar 11 Bedroom Holiday Home by Five Star Properties
House, 6 Bedrooms, Ocean View, Beachfront | Balcony
Capitano 7 Bedroom Holiday Home by Five Star Properties
5.0 star property
Capitano 7 Bedroom Holiday Home by Five Star Properties
House, Multiple Beds | Pool | Outdoor pool
Palazzo del Mar by Five Star Properties
5.0 star property
Palazzo del Mar by Five Star Properties
House, 6 Bedrooms, Ocean View, Beachfront | Staircase
Millenia 7 Bedroom Holiday Home by Five Star Properties
5.0 star property
Millenia 7 Bedroom Holiday Home by Five Star Properties
House, 4 Bedrooms, Ocean View, Sea Facing | BBQ/picnic Area
Vista del Mare 4 Bedroom Holiday Home by Five Star Properties
5.0 star property
Vista del Mare 4 Bedroom Holiday Home by Five Star Properties
House, 4 Bedrooms | Pool | Outdoor pool
Casa Esmeralda by Five Star Properties
5.0 star property
Casa Esmeralda by Five Star Properties
House, 6 Bedrooms, Ocean View, Sea Facing | Aerial view
Stranded on a Sandbar 8 Bedroom Holiday Home by Five Star Properties
5.0 star property
Stranded on a Sandbar 8 Bedroom Holiday Home by Five Star Properties
House, 5 Bedrooms, Ocean View, Sea Facing | Front of property – evening/night
Casa de Palms 5 Bedroom Holiday Home by Five Star Properties
5.0 star property
Casa de Palms 5 Bedroom Holiday Home by Five Star Properties
House, 5 Bedrooms | Pool | Outdoor pool
Modern Paradise by Five Star Properties
5.0 star property
Modern Paradise by Five Star Properties

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Destin.
The Island Resort at Fort Walton Beach

The Island Resort at Fort Walton Beach

Miracle Strip Parkway Southeast, 1500, Fort Walton Beach, FL
The price is £225 per night from May 12 to May 13
£225
per night
12 May - 13 May
8.2/10 Very Good! (1,870 reviews)
Still don't see what you're looking for?
See all properties in Destin.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.