Compare and book 5 Star hotels in Central West End, St. Louis
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Central West End 5 Star Hotels
Our top choices for Central West End 5-star hotels
9.4 out of 10, Exceptional, (1,006 reviews)
"The absolute best place to stay in St Louis."
Brandy
The price is £326
includes taxes & fees
13 Aug - 14 Aug
9.2 out of 10, Wonderful, (578 reviews)
"Incredible stay! Loved the room, the staff were great, and the amenities were amazing! Definitely recommend staying here!"
Kennedy
The price is £554
includes taxes & fees
10 Aug - 11 Aug
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Central West End.
Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road St. Louis MO
The price is £96 per night from 29 Aug to 30 Aug
£96
29 Aug - 30 Aug
includes taxes & fees
8.4/10 Very good! (1,128 reviews)
Still don't see what you're looking for?
See all properties in Central West End.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Central West End
Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.
Top Central West End Hotel Reviews
Frequently asked questions
Explore a world of travel with Expedia
- 5 Star Hotels in Chesterfield
- 5 Star Hotels in St. Louis
- Hotels near Barnes Jewish Hospital
- Red Lion Hotels in Brentwood
- Hotels near Busch Stadium
- Central West End Hotels
- Gay-Friendly Hotels in Creve Coeur
- Hotels near Dome at America’s Center
- Hotels near Enterprise Center
- Hotels near Gateway Arch
- Hotels near River City Casino
- Best Western St. Louis
- Boyd Gaming Hotels in St. Louis
- Cheap Hotels in St. Louis
- Hotels with Waterslides in St. Louis
- St. Louis Hotels
- Hotels near St. Louis Union Station
- University City Hotels
- Flights to Kirkwood
- Flights to Lambert-St. Louis Intl.
- Flights to St. Louis
- Flights from Lambert-St. Louis Intl.
- British Airways London (LHR) to St. Louis (STL) flights
- British Airways Manchester (MAN) to St. Louis (STL) flights
- Delta Minneapolis (MSP) to St. Louis (STL) flights
- Jetblue Airways New York (JFK) to St. Louis (STL) flights
- Jetblue Airways Boston (BOS) to St. Louis (STL) flights
- Flights from St. Louis
- Flights from Aberdeen (ABZ) to St. Louis (STL)
- Flights from Amsterdam (AMS) to St. Louis (STL)
- Flights from Atlanta (ATL) to St. Louis (STL)
- Flights from Austin (AUS) to St. Louis (STL)
- Flights from Belfast (BFS) to St. Louis (STL)
- Flights from Birmingham (BHM) to St. Louis (STL)
- Flights from Birmingham (BHX) to St. Louis (STL)
- Flights from Nashville (BNA) to St. Louis (STL)
- Flights from Boston (BOS) to St. Louis (STL)
- Flights from Bristol (BRS) to St. Louis (STL)
- Flights from Baltimore (BWI) to St. Louis (STL)
- Flights from Columbia (CAE) to St. Louis (STL)
- Flights from Paris (CDG) to St. Louis (STL)
- Flights from Columbus (CMH) to St. Louis (STL)
- Flights from Cincinnati (CVG) to St. Louis (STL)
- Flights from Washington (DCA) to St. Louis (STL)
- Flights from Dallas (DFW) to St. Louis (STL)
- Flights from Detroit (DTW) to St. Louis (STL)
- Flights from Dublin (DUB) to St. Louis (STL)
- Flights from Entebbe (EBB) to St. Louis (STL)
- Flights from Edinburgh (EDI) to St. Louis (STL)
- Flights from East Midlands (EMA) to St. Louis (STL)
- Flights from Newark Liberty Intl. Airport (EWR) to St. Louis (STL)
- Flights from Frankfurt (FRA) to St. Louis (STL)
- Flights from Glasgow (GLA) to St. Louis (STL)
- Flights from Houston (IAH) to St. Louis (STL)
- Flights from New York (JFK) to St. Louis (STL)
- Flights from Las Vegas (LAS) to St. Louis (STL)
- Flights from Los Angeles (LAX) to St. Louis (STL)
- Flights from London (LCY) to St. Louis (STL)
- Flights from New York (LGA) to St. Louis (STL)
- Flights from London (LGW) to St. Louis (STL)
- Flights from London (LHR) to St. Louis (STL)
- Flights from London (LON) to St. Louis (STL)
- Flights from Liverpool (LPL) to St. Louis (STL)
- Flights from Manchester (MAN) to St. Louis (STL)
- Flights from Kansas City (MCI) to St. Louis (STL)
- Flights from Orlando (MCO) to St. Louis (STL)
- Flights from Memphis (MEM) to St. Louis (STL)
- Flights from Mexico City (MEX) to St. Louis (STL)
- Flights from Miami (MIA) to St. Louis (STL)
- Flights from Durham (MME) to St. Louis (STL)
- Flights from Newcastle (NCL) to St. Louis (STL)
- Flights from Norwich (NWI) to St. Louis (STL)
- Flights from New York (NYC) to St. Louis (STL)
- Flights from Chicago (ORD) to St. Louis (STL)
- Flights from Norfolk (ORF) to St. Louis (STL)
- Flights from Philadelphia (PHL) to St. Louis (STL)
- Flights from Pittsburgh (PIT) to St. Louis (STL)
- Flights from Richmond (RIC) to St. Louis (STL)
- Flights from San Diego (SAN) to St. Louis (STL)
- Flights from Seattle (SEA) to St. Louis (STL)
- Flights from San Francisco (SFO) to St. Louis (STL)
- Flights from Southampton (SOU) to St. Louis (STL)
- Flights from Montreal (YUL) to St. Louis (STL)
- Flights from Toronto (YYZ) to St. Louis (STL)