Title: The 10 Best 5 Star Hotels in Central West End - 2026 Updated Prices | Expedia.co.uk [Central West End Travel Guide](https://expedia.co.uk/St-Louis-Central-West-End.dx6175135)[Holiday Rentals in St. Louis](https://expedia.co.uk/St-Louis-Holiday-Rentals.d178309.Travel-Guide-HolidayRentals)[Flights to St. Louis](https://expedia.co.uk/Cheap-Flights-To-St-Louis.d178309.Travel-Guide-Flights)[Things to do in St. Louis](https://expedia.co.uk/Things-To-Do-In-St-Louis.d178309.Travel-Guide-Activities)[Central West End Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Central-West-End.d6175135.Car-Hire-Guide)[Central West End Holidays](https://expedia.co.uk/Central-West-End.d6175135.Holidays-City-Breaks) ![Central West End featuring outdoor eating and a city as well as a small group of people](https://images.trvl-media.com/place/6175135/3b810abc-d225-41b1-ad50-a6a70648e357.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Compare and book 5 Star hotels in Central West End, St. Louis - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Central West End 5 Star Hotels Tonight [31 Dec - 1 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6175135&startDate=2025-12-31&endDate=2026-01-01&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [1 Jan - 2 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6175135&startDate=2026-01-01&endDate=2026-01-02&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6175135&startDate=2026-01-02&endDate=2026-01-04&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [9 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6175135&startDate=2026-01-09&endDate=2026-01-11&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Central West End 5-star hotels ![Rooftop bar](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/89e020ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop bar](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/5b370fff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/e177092f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), hot tub, body treatments, aromatherapy](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/941b0ba8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Seasons Hotel St Louis [](https://www.expedia.co.uk/St-Louis-Hotels-Four-Seasons-Hotel-St-Louis.h2851438.Hotel-Information) Downtown St. Louis 9.4/10 Exceptional (1001) "Everything exceeded my expectations from the welcoming staff to the luxuriously appointed room, to the 4 feet deep bathtub in which to soak my cares away--it was a total dream come true. I would come back in a heartbeat at this home away from home. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lynne £359 includes taxes & fees 2 Jan - 3 Jan 2026 [](https://www.expedia.co.uk/St-Louis-Hotels-Four-Seasons-Hotel-St-Louis.h2851438.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/6200/6132/9a597e77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/10000/6200/6132/w4000h2663x0y0-dfd3faff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/6200/6132/dbe99670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/6200/6132/a54897ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Ritz-Carlton, St. Louis [](https://www.expedia.co.uk/St-Louis-Hotels-The-Ritz-Carlton.h6132.Hotel-Information) Clayton 9.2/10 Wonderful (554) "The stay was ok even though nothing was explained to be. The hours of restaurant, where the gym is located about the bar in the room nothing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shemelle £431 includes taxes & fees 1 Jan - 2 Jan 2026 [](https://www.expedia.co.uk/St-Louis-Hotels-The-Ritz-Carlton.h6132.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Central-West-End-St-Louis-Hotels.s50-n6175135-0.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Central-West-End-St-Louis-Hotels.s50-n6175135-0.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Central West End. ![Magnolia Hotel St. Louis, a Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/4b87c2a3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Magnolia Hotel St. Louis, a Tribute Portfolio Hotel 421 N 8th St St. Louis MO £86 25 Jan - 26 Jan 2026 includes taxes & fees 8.6/10 Excellent! (1,173 reviews) [](https://expedia.co.uk/St-Louis-Hotels-Magnolia-Hotel-St-Louis.h8131949.Hotel-Information) ![Hyatt Regency St. Louis at The Arch](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/335a172e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hyatt Regency St. Louis at The Arch 315 Chestnut St St. Louis MO £113 2 Jan - 3 Jan 2026 includes taxes & fees 8.4/10 Very Good! (4,041 reviews) [](https://expedia.co.uk/St-Louis-Hotels-Hyatt-Regency-St-Louis-At-The-Arch.h14877.Hotel-Information) ![Hilton St. Louis Frontenac](https://images.trvl-media.com/lodging/1000000/10000/2100/2054/68baaab6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hilton St. Louis Frontenac 1335 S Lindbergh Blvd Frontenac MO £112 18 Jan - 19 Jan 2026 includes taxes & fees 8.6/10 Excellent! (1,004 reviews) [](https://expedia.co.uk/St-Louis-Hotels-Hilton-St-Louis-Frontenac.h2054.Hotel-Information) Still don't see what you're looking for? [See all properties in Central West End.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=01%2F01%2F2026&endDate=02%2F01%2F2026®ionId=6175135&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=01%2F01%2F2026&endDate=02%2F01%2F2026®ionId=6175135&star=50&star=50&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=01%2F01%2F2026&endDate=02%2F01%2F2026®ionId=6175135&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=01%2F01%2F2026&endDate=02%2F01%2F2026®ionId=6175135&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=01%2F01%2F2026&endDate=02%2F01%2F2026®ionId=6175135&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=01%2F01%2F2026&endDate=02%2F01%2F2026®ionId=6175135&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Central West End Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees. [See all hotels in Central West End](https://www.expedia.co.uk/Hotel-Search?startDate=2026-01-14&endDate=2026-01-15&adults=2®ionId=6175135) ![Central West End](https://images.trvl-media.com/place/6175135/69dc69e3-2092-4ca9-a34e-3187d2801679.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top Central West End Hotel Reviews ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Central West End? > - Search for the lowest price per night from £86 ### What makes a hotel 5 stars in Central West End? ### Are there any 5-star all-inclusive resorts in Central West End? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [5 Star Hotels in Chesterfield ](https://www.expedia.co.uk/5Star-Chesterfield-Hotels.s50-0-d9530.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Kirkwood ](https://www.expedia.co.uk/5Star-Kirkwood-Hotels.s50-0-d8470.Travel-Guide-Filter-Hotels) - [5 Star Hotels in St. Louis ](https://www.expedia.co.uk/5Star-St-Louis-Hotels.s50-0-d178309.Travel-Guide-Filter-Hotels) - 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