Title: The 10 Best 5 Star Hotels in Andean Natural Region - 2026 Updated Prices | Expedia.co.uk [Andean Natural Region Travel Guide](https://expedia.co.uk/Andean-Natural-Region.dx6053679)[Hotels in Andean Natural Region](https://expedia.co.uk/Andean-Natural-Region-Hotels.d6053679.Travel-Guide-Hotels)[Holiday Rentals in Andean Natural Region](https://expedia.co.uk/Andean-Natural-Region-Holiday-Rentals.d6053679.Travel-Guide-HolidayRentals)[Flights to Andean Natural Region](https://expedia.co.uk/Cheap-Flights-To-Andean-Natural-Region.d6053679.Travel-Guide-Flights)[Andean Natural Region Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Andean-Natural-Region.d6053679.Car-Hire-Guide)[Andean Natural Region Holidays](https://expedia.co.uk/Andean-Natural-Region.d6053679.Holidays-City-Breaks) ![Monserrate showing a house, mountains and landscape views](https://images.trvl-media.com/place/6071659/9ade5c38-18df-4be1-84a2-1d7ef2ca873f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6071659/9ade5c38-18df-4be1-84a2-1d7ef2ca873f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Andean Natural Region 5 Star Hotels Tonight [22 Feb - 23 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6053679&startDate=2026-02-22&endDate=2026-02-23&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [23 Feb - 24 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6053679&startDate=2026-02-23&endDate=2026-02-24&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [27 Feb - 1 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6053679&startDate=2026-02-27&endDate=2026-03-01&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [6 Mar - 8 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6053679&startDate=2026-03-06&endDate=2026-03-08&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Andean Natural Region 5-star hotels ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/2000000/1950000/1946400/1946355/a8577ee4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1950000/1946400/1946355/f0838728.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1950000/1946400/1946355/ddcda876.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1950000/1946400/1946355/08a57d3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NH Collection Medellín Royal [](https://www.expedia.co.uk/Medellin-Hotels-NH-Collection-Medellin-Royal.h1946355.Hotel-Information) El Poblado 9.2/10 Wonderful (1,007 reviews) "Great hotel in a good location" ![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg) Maria £73 additional charges may apply 23 Mar - 24 Mar [](https://www.expedia.co.uk/Medellin-Hotels-NH-Collection-Medellin-Royal.h1946355.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/34000000/33250000/33241200/33241103/0f8a5005.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/34000000/33250000/33241200/33241103/2e25fb9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/34000000/33250000/33241200/33241103/0a2d82bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/34000000/33250000/33241200/33241103/dda8c29e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Click Clack Hotel Medellin [](https://www.expedia.co.uk/Medellin-Hotels-The-Click-Clack-Hotel-Medellin.h33241103.Hotel-Information) El Poblado 9.2/10 Wonderful (1,099 reviews) "Beautiful place, great breakfast. The pool was amazing " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie £179 additional charges may apply 2 Mar - 3 Mar [](https://www.expedia.co.uk/Medellin-Hotels-The-Click-Clack-Hotel-Medellin.h33241103.Hotel-Information) ![Sun deck](https://images.trvl-media.com/lodging/5000000/4130000/4129400/4129341/b0cf1d51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/5000000/4130000/4129400/4129341/fda949e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Park View | Living area | 42-inch plasma TV with satellite channels, TV, iPod dock](https://images.trvl-media.com/lodging/5000000/4130000/4129400/4129341/6d9487c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/5000000/4130000/4129400/4129341/f23262f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Charlee Hotel [](https://www.expedia.co.uk/Medellin-Hotels-The-Charlee-Hotel.h4129341.Hotel-Information) El Poblado 8.8/10 Excellent (1,006 reviews) "Loved the location hotel was beautiful. Had an amazing rooftop." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leslie [](https://www.expedia.co.uk/Medellin-Hotels-The-Charlee-Hotel.h4129341.Hotel-Information) ![Presidential Suite, 1 King Bed | Bathroom | Combined shower/bathtub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/20000000/19300000/19295500/19295426/2c22ba0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/20000000/19300000/19295500/19295426/046c36a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 King Bed | Living room | 50-inch Smart TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/20000000/19300000/19295500/19295426/a820a67f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 King Bed | Bathroom | Combined shower/bathtub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/20000000/19300000/19295500/19295426/7783621b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Medellin Marriott Hotel [](https://www.expedia.co.uk/Medellin-Hotels-Medellin-Marriott-Hotel.h19295426.Hotel-Information) El Poblado 8.8/10 Excellent (594 reviews) "Great property, friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vidal £244 additional charges may apply 27 Feb - 28 Feb [](https://www.expedia.co.uk/Medellin-Hotels-Medellin-Marriott-Hotel.h19295426.Hotel-Information) ![Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100050000/100048700/100048622/2290dcc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor spa tub](https://images.trvl-media.com/lodging/101000000/100050000/100048700/100048622/98d0bb9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/101000000/100050000/100048700/100048622/w5982h3992x10y0-4862077f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/101000000/100050000/100048700/100048622/4021126c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury Suites Prana By Cadissa [](https://www.expedia.co.uk/Medellin-Hotels-Luxury-Suites-Prana-By-Cadissa.h100048622.Hotel-Information) Laureles - Estadio 9.2/10 Wonderful (38 reviews) "We liked the comfort and the quiet neighbourhood, excellent staff and very knowledgeable and helpful. Beautiful place, will definitely stay there again." ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Eduardo Hernandez £80 additional charges may apply 24 Feb - 25 Feb [](https://www.expedia.co.uk/Medellin-Hotels-Luxury-Suites-Prana-By-Cadissa.h100048622.Hotel-Information) ![Double Room, Bathtub | Premium bedding, minibar, in-room safe, bed sheets](https://images.trvl-media.com/lodging/116000000/115830000/115824100/115824083/fe702ccb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/116000000/115830000/115824100/115824083/89c895c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/116000000/115830000/115824100/115824083/d651a8e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, bed sheets](https://images.trvl-media.com/lodging/116000000/115830000/115824100/115824083/daac7633.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ecolodge Palonegro [](https://www.expedia.co.uk/Bucaramanga-Hotels-Ecolodge-Palonegro.h115824083.Hotel-Information) Lebrija 9.4/10 Exceptional (8 reviews) "Beautiful! Highly " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Elizabeth £95 additional charges may apply 24 Feb - 25 Feb [](https://www.expedia.co.uk/Bucaramanga-Hotels-Ecolodge-Palonegro.h115824083.Hotel-Information) ![Exclusive Duplex, City View | View from room](https://images.trvl-media.com/lodging/118000000/117410000/117402700/117402672/0c1b4f56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Apartment, City View | Living area | 50-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/118000000/117410000/117402700/117402672/93f7b1c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Duplex, City View | Bathroom | Shower, rainfall showerhead, eco-friendly toiletries, hair dryer](https://images.trvl-media.com/lodging/118000000/117410000/117402700/117402672/ae357e83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Duplex, City View | Terrace/patio](https://images.trvl-media.com/lodging/118000000/117410000/117402700/117402672/a146dd27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Morph by MOME Stays [](https://www.expedia.co.uk/Medellin-Hotels-Morph-By-MOME-Stays.h117402672.Hotel-Information) El Poblado 10/10 Exceptional (2 reviews) "Aa" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mario [](https://www.expedia.co.uk/Medellin-Hotels-Morph-By-MOME-Stays.h117402672.Hotel-Information) ![Premium bedding, down duvets, pillow-top beds, minibar](https://images.trvl-media.com/lodging/95000000/94750000/94745900/94745802/0126ae13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/95000000/94750000/94745900/94745802/3072b6ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/95000000/94750000/94745900/94745802/9aadefb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Loft | Premium bedding, down duvets, pillow-top beds, minibar](https://images.trvl-media.com/lodging/95000000/94750000/94745900/94745802/e68303fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOBBIT HOTEL [](https://www.expedia.co.uk/El-Penol-Hotels-CONTAINER-HOBBIT-GLAMPING.h94745802.Hotel-Information) El Peñol 10/10 Exceptional (2 reviews) "Had a wonderful stay with Monica and Jairo in their lovely space. The beds were super comfortable, the pillows heavenly, and the towels fluffy. My hosts were very hospitable and made my stay as pleasant as possible. They were eager to help, open feedback, and proactive in terms of resolving issues. Would love to return on my next visit!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tanya £76 additional charges may apply 24 Feb - 25 Feb [](https://www.expedia.co.uk/El-Penol-Hotels-CONTAINER-HOBBIT-GLAMPING.h94745802.Hotel-Information) ![Exclusive House, Smoking, Garden View | Private kitchen | Microwave](https://images.trvl-media.com/lodging/91000000/90850000/90841100/90841057/a1c8efc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90850000/90841100/90841057/d121b0ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exclusive Room | Frette Italian sheets, premium bedding, down duvets, Tempur-Pedic beds](https://images.trvl-media.com/lodging/91000000/90850000/90841100/90841057/c487223d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90850000/90841100/90841057/4c432fb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### CASA SUYTE LEGUIZAMON [](https://www.expedia.co.uk/Envigado-Hotels-CASA-SUYTE-LEGUIZAMON.h90841057.Hotel-Information) Envigado 2.0/10 (1 review) "I can't talked about the hotel, i only can tell you, i was lost to get to the hotel, and when I called to the hotel to get the exact location, they told me they don't any vacants until 2024\. Thanks God that i could contact Karla from Customer Service by email(because i don't have phone service in Colombia) and she do the process with me to put me in another hotel. She was extremely helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julio [](https://www.expedia.co.uk/Envigado-Hotels-CASA-SUYTE-LEGUIZAMON.h90841057.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/104000000/103380000/103372400/103372315/bdd6e628.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/104000000/103380000/103372400/103372315/157730d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/104000000/103380000/103372400/103372315/2b5b3b67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/104000000/103380000/103372400/103372315/dfe5a3e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 30 Living Suites [](https://www.expedia.co.uk/Medellin-Hotels-30-Living.h103372315.Hotel-Information) Belen 9.0/10 Wonderful (149 reviews) "Everything was amazing!! Staff super friendly and helpful. Breakfast was delicious." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Juan [](https://www.expedia.co.uk/Medellin-Hotels-30-Living.h103372315.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Andean-Natural-Region-Hotels.s50-0-d6053679.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Andean-Natural-Region-Hotels.s50-0-d6053679.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Andean Natural Region. ![Hotel Dorado La 70](https://images.trvl-media.com/lodging/12000000/11580000/11575400/11575368/f4b76736_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Dorado La 70 Carrera 70 No 44 B-66 Medellín £44 28 Feb - 1 Mar additional charges may apply 8.8/10 Excellent! (1,854 reviews) [](https://expedia.co.uk/Medellin-Hotels-Hotel-Dorado-La-70.h11575368.Hotel-Information) ![Heiss Hotel By Jalo](https://images.trvl-media.com/lodging/106000000/105650000/105647300/105647272/4877276a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Heiss Hotel By Jalo 1460 Cra. 43F Medellín Antioquia £54 15 Mar - 16 Mar additional charges may apply 9/10 Wonderful! (1,204 reviews) [](https://expedia.co.uk/Medellin-Hotels-Hotel-Heiss.h105647272.Hotel-Information) ![Dann Carlton Medellin Hotel](https://images.trvl-media.com/lodging/1000000/120000/112600/112569/9343ad6c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Dann Carlton Medellin Hotel Carrera 43a No.7-50, Avenida El Poblado Medellín Antioquia £66 1 Mar - 2 Mar additional charges may apply 8.8/10 Excellent! (1,758 reviews) [](https://expedia.co.uk/Medellin-Hotels-Dann-Carlton-Medellin-Hotel.h112569.Hotel-Information) Still don't see what you're looking for? [See all properties in Andean Natural Region.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=24%2F02%2F2026&endDate=25%2F02%2F2026®ionId=6053679&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=24%2F02%2F2026&endDate=25%2F02%2F2026®ionId=6053679&star=50&star=50&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=24%2F02%2F2026&endDate=25%2F02%2F2026®ionId=6053679&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=24%2F02%2F2026&endDate=25%2F02%2F2026®ionId=6053679&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=24%2F02%2F2026&endDate=25%2F02%2F2026®ionId=6053679&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=24%2F02%2F2026&endDate=25%2F02%2F2026®ionId=6053679&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Andean Natural Region This Colombian region of rugged contours and diverse climates enthralls with its fascinating indigenous customs and its hearty local cuisine. [See all hotels in Andean Natural Region](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-09&endDate=2026-03-10&adults=2®ionId=6053679) ![Monserrate showing a house, mountains and landscape views](https://images.trvl-media.com/place/6071659/9ade5c38-18df-4be1-84a2-1d7ef2ca873f.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top Andean Natural Region Hotel Reviews ![NH Collection Medellín Royal](https://images.trvl-media.com/lodging/2000000/1950000/1946400/1946355/c817fea7_y.jpg) ### NH Collection Medellín Royal 10/10 Excellent "Amazing stay! The room was spotless and comfortable, the staff was incredibly kind, and the service was top-tier. The location was great and the overall experience exceeded our expectations. Would definitely stay here again!" [](https://expedia.co.uk/Medellin-Hotels-NH-Collection-Medellin-Royal.h1946355.Hotel-Information) ![The Click Clack Hotel Medellin](https://images.trvl-media.com/lodging/34000000/33250000/33241200/33241103/e335d89f_y.jpg) ### The Click Clack Hotel Medellin 10/10 Excellent "excellent " [](https://expedia.co.uk/Medellin-Hotels-The-Click-Clack-Hotel-Medellin.h33241103.Hotel-Information) ## Find out more about Andean Natural Region ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - [Farmstay in Colombia ](https://www.expedia.co.uk/Colombia-Agritourism.d38-aaAgritourism.Travel-Guide-Accommodation) - [Serviced Apartments in Colombia ](https://www.expedia.co.uk/Colombia-Apart-Hotels.d38-aaApartHotels.Travel-Guide-Accommodation) - [Apartments in Colombia ](https://www.expedia.co.uk/Colombia-Apartments.d38-aaApartments.Travel-Guide-Accommodation) - [B&B in Colombia ](https://www.expedia.co.uk/Colombia-Bed-And-Breakfasts.d38-aaBedAndBreakfasts.Travel-Guide-Accommodation) - 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