Title: The 10 Best 4 Star Hotels in Southeastern Indiana - 2026 Updated Prices | Expedia.co.uk [Southeastern Indiana Travel Guide](https://expedia.co.uk/Southeastern-Indiana.dx6233889)[Hotels in Southeastern Indiana](https://expedia.co.uk/Southeastern-Indiana-Hotels.d6233889.Travel-Guide-Hotels)[Holiday Rentals in Southeastern Indiana](https://expedia.co.uk/Southeastern-Indiana-Holiday-Rentals.d6233889.Travel-Guide-HolidayRentals)[Flights to Southeastern Indiana](https://expedia.co.uk/Cheap-Flights-To-Southeastern-Indiana.d6233889.Travel-Guide-Flights)[Southeastern Indiana Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southeastern-Indiana.d6233889.Car-Hire-Guide)[Southeastern Indiana Holidays](https://expedia.co.uk/Southeastern-Indiana.d6233889.Holidays-City-Breaks) ![Bathe in the forest...find this on the roof of the outdoor shower house down the hill from the guest house.](https://images.trvl-media.com/place/553248635989202622/88a60920-d501-4b4d-b386-caf78a7f4191.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Serendipity Trip # Compare and book 4 Star hotels in Southeastern Indiana, United States of America - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southeastern Indiana 4 Star Hotels Tonight [11 Jan - 12 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6233889&startDate=2026-01-11&endDate=2026-01-12&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [12 Jan - 13 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6233889&startDate=2026-01-12&endDate=2026-01-13&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6233889&startDate=2026-01-16&endDate=2026-01-18&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6233889&startDate=2026-01-23&endDate=2026-01-25&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Southeastern Indiana 4-star hotels ![4 restaurants, breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/e725185b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/23521baa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms, Non Smoking (East Twr, Waterview, 2 Queens, 1 King) | In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/38ee770d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/9c82234b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Galt House Hotel Trademark Collection by Wyndham [](https://www.expedia.co.uk/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) Downtown Louisville 9.0/10 Wonderful (3,973 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carlos £117 includes taxes & fees 28 Jan - 29 Jan [](https://www.expedia.co.uk/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) ![3 bars/lounges, cocktail bar, lobby lounge](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/78105fdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, cocktail bar, lobby lounge](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/547de83e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/0bb1b93b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 6:30 AM to 10:00 PM, pool cabanas (surcharge)](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/e2fb9d56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omni Louisville Hotel [](https://www.expedia.co.uk/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information) Downtown Louisville 9.2/10 Wonderful (1,763 reviews) "One of the nicest hotels I’ve ever stayed at. Amazing property!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £147 includes taxes & fees 24 Jan - 25 Jan [](https://www.expedia.co.uk/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/5bea9d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Corner | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/07f1fa14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, pool loungers](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/edc62f96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/408d438d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites Louisville Downtown [](https://www.expedia.co.uk/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information) Downtown Louisville 9.0/10 Wonderful (1,148 reviews) "Great room and breakfast. Close to several nice restaurants." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Crystal £107 includes taxes & fees 26 Jan - 27 Jan [](https://www.expedia.co.uk/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/840e31de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/4fd8456f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/2a2a7fb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/f0221042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Brown Hotel [](https://www.expedia.co.uk/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information) Downtown Louisville 9.4/10 Exceptional (1,171 reviews) "Fantastic place to stay in Louisville." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nathaniel [](https://www.expedia.co.uk/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/1b9613a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/w3836h2558x4y3-11fbb096.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, cocktail bar, rooftop bar](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/8178d3c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/w2691h3837x0y3-df7daefb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Genevieve part of JdV by Hyatt [](https://www.expedia.co.uk/Louisville-Hotels-Hotel-Genevieve.h90942141.Hotel-Information) Downtown Louisville 9.2/10 Wonderful (1,028 reviews) "Spotless room and courteous staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary £102 includes taxes & fees 12 Jan - 13 Jan [](https://www.expedia.co.uk/Louisville-Hotels-Hotel-Genevieve.h90942141.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/a9b7038a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (Asleep in the Cyclone) | Premium bedding, down duvets, minibar, in-room safe](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/fdd94051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/06213b95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/864ff441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 21c Museum Hotel Louisville [](https://www.expedia.co.uk/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information) Downtown Louisville 9.2/10 Wonderful (1,005 reviews) "Excellent place. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anatole £115 includes taxes & fees 31 Jan - 1 Feb [](https://www.expedia.co.uk/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/e017e8a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/06086a53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (VIP) | Premium bedding, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/b7d53e76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/1a50697e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Louisville [](https://www.expedia.co.uk/Louisville-Hotels-Hyatt-Regency-Louisville.h326983.Hotel-Information) Downtown Louisville 8.8/10 Excellent (1,003 reviews) "Great hotel close to 4th street. Overall nice stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Collin £130 includes taxes & fees 20 Jan - 21 Jan [](https://www.expedia.co.uk/Louisville-Hotels-Hyatt-Regency-Louisville.h326983.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/e116c623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/e68de90e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; local cuisine ](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/765b8556.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Single Room, 1 King Bed, City View | Frette Italian sheets, premium bedding, free WiFi, bed sheets](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/f924fe21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Grady [](https://www.expedia.co.uk/Louisville-Hotels-The-Grady.h61215907.Hotel-Information) Downtown Louisville 9.4/10 Exceptional (1,001 reviews) "Such an amazing hotel...restaurant is delicious! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Craig £127 includes taxes & fees 31 Jan - 1 Feb [](https://www.expedia.co.uk/Louisville-Hotels-The-Grady.h61215907.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/c5a6934a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/6f6867fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 Bedroom | Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/1c073add.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/19be2c84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Louisville Marriott Downtown [](https://www.expedia.co.uk/Louisville-Hotels-Louisville-Marriott-Downtown.h1111358.Hotel-Information) Downtown Louisville 9.0/10 Wonderful (1,002 reviews) "Very nice hotel. Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brad £158 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Louisville-Hotels-Louisville-Marriott-Downtown.h1111358.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/ac66f01b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch flat-screen TV with satellite channels, TV](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/939655b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/16484a66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/8fba23fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Distil, Autograph Collection [](https://www.expedia.co.uk/Louisville-Hotels-Hotel-Distil.h37765616.Hotel-Information) Downtown Louisville 9.6/10 Exceptional (432 reviews) "Clean, well appointed, convenient to restaurants and downtown Louisville." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chris £161 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Louisville-Hotels-Hotel-Distil.h37765616.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/5c616865.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Corner](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/c93e1deb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/f1158083.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, American cuisine](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/12fca7c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Bourré Bonne Louisville, Curio Collection by Hilton [](https://www.expedia.co.uk/Louisville-Hotels-Canopy-By-Hilton-Louisville-Downtown.h107072728.Hotel-Information) Downtown Louisville 9.2/10 Wonderful (62 reviews) "Amazing property! Best hotel in Louisville! Will be staying there again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Norman £148 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Louisville-Hotels-Canopy-By-Hilton-Louisville-Downtown.h107072728.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/d22f4bf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hilton, Deluxe Suite, 1 Queen Bed, Non Smoking | Living area | 55-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/83bc3758.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/52012810.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/w3839h2557x0y0-ff0d1f72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Seelbach Hilton Louisville Downtown [](https://www.expedia.co.uk/Louisville-Hotels-The-Seelbach-Hilton-Louisville.h25958.Hotel-Information) Downtown Louisville 8.6/10 Excellent (1,001 reviews) "Excellent location and a great lobby bar with a top notch bourbon selection. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) vincent £125 includes taxes & fees 16 Jan - 17 Jan [](https://www.expedia.co.uk/Louisville-Hotels-The-Seelbach-Hilton-Louisville.h25958.Hotel-Information) ![Lounge](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/3f80acf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/af58ac58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Suite, 1 Queen Bed, Non Smoking | Premium bedding, down duvets, memory-foam beds, individually furnished](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/e9ed9b4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Suite, 1 King Bed, Non Smoking | Premium bedding, down duvets, memory-foam beds, individually furnished](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/d0d55041.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stellar Suites [](https://www.expedia.co.uk/Louisville-Hotels-Stellar-Suites.h90953532.Hotel-Information) Downtown Louisville 9.6/10 Exceptional (119 reviews) "The check-in process was simple and easy, the room was spotless and had so many amenities. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Grace £132 includes taxes & fees 29 Jan - 30 Jan [](https://www.expedia.co.uk/Louisville-Hotels-Stellar-Suites.h90953532.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/17000000/16890000/16881700/16881647/ee4c1d5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/17000000/16890000/16881700/16881647/3ff12f20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/17000000/16890000/16881700/16881647/5cef01cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor wedding area](https://images.trvl-media.com/lodging/17000000/16890000/16881700/16881647/19f1cd24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Pepin Mansion Historic B&B [](https://www.expedia.co.uk/Louisville-Hotels-The-Pepin-Mansion-Historic-BB.h16881647.Hotel-Information) New Albany 9.8/10 Exceptional (651 reviews) "This is our second visit this year. Lovely and comfortable rooms. Breakfast was wonderful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) douglas f £75 includes taxes & fees 12 Jan - 13 Jan [](https://www.expedia.co.uk/Louisville-Hotels-The-Pepin-Mansion-Historic-BB.h16881647.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/103000000/102320000/102311400/102311340/2e0c62b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/103000000/102320000/102311400/102311340/af73a8ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 2 Bedrooms, Non Smoking | Laptop workspace, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/103000000/102320000/102311400/102311340/48d338aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Bedroom, Non Smoking | Terrace/patio](https://images.trvl-media.com/lodging/103000000/102320000/102311400/102311340/w2493h1667x0y0-491d9ec0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### CozySuites at Nulu [](https://www.expedia.co.uk/Louisville-Hotels-CozySuites-At-Nulu.h102311340.Hotel-Information) Downtown Louisville 8.2/10 Very good (26 reviews) "The unit was clean, all communications were timely, the property has all the amenities, and NULU is very walkable. A perfect stay! My only regret is that I wasn't able to extend the stay. Highly recommended if you're in the Louisville area " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William £146 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Louisville-Hotels-CozySuites-At-Nulu.h102311340.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/103000000/102200000/102190400/102190334/bb9c61a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/103000000/102200000/102190400/102190334/e576ef26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/103000000/102200000/102190400/102190334/6ec16319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room dining](https://images.trvl-media.com/lodging/103000000/102200000/102190400/102190334/e906c2d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### stayAPT Suites Louisville North-Clarksville [](https://www.expedia.co.uk/Louisville-Hotels-StayAPT-Suites-Louisville-N-Clarksville.h102190334.Hotel-Information) Clarksville 9.8/10 Exceptional (46 reviews) "room very good i love hotel ❤️" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kartar £112 includes taxes & fees 13 Jan - 14 Jan [](https://www.expedia.co.uk/Louisville-Hotels-StayAPT-Suites-Louisville-N-Clarksville.h102190334.Hotel-Information) ![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/00e4c915.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/071da00d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/2ec829de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/eec2d0c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Reserve on Main [](https://www.expedia.co.uk/Louisville-Hotels-The-Reserve-On-Main.h121877336.Hotel-Information) Downtown Louisville 10/10 Exceptional (1 review) "Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) georgios £180 includes taxes & fees 14 Jan - 15 Jan [](https://www.expedia.co.uk/Louisville-Hotels-The-Reserve-On-Main.h121877336.Hotel-Information) ![Family House, Multiple Beds | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/25000000/24380000/24372500/24372412/3b698b60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/25000000/24380000/24372500/24372412/8410ecaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, Multiple Beds | View from room](https://images.trvl-media.com/lodging/25000000/24380000/24372500/24372412/fa524ab2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/25000000/24380000/24372500/24372412/aebabcae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb [](https://www.expedia.co.uk/Sellersburg-Hotels-Spacious-3-BR-Ranch-House-Wpatio-Yard-In-A-Quiet-Suburb.h24372412.Hotel-Information) Sellersburg 9.4/10 Exceptional (10 reviews) "Very nice house in a nice neighborhood, spacious home environmental, felt more that at home there," ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tammy [](https://www.expedia.co.uk/Sellersburg-Hotels-Spacious-3-BR-Ranch-House-Wpatio-Yard-In-A-Quiet-Suburb.h24372412.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/103000000/102380000/102374400/102374386/d5f75e71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms, Non Smoking | Living area | 42-inch Smart TV with digital channels, Netflix, Hulu](https://images.trvl-media.com/lodging/103000000/102380000/102374400/102374386/63eb2392.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms, Non Smoking | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/103000000/102380000/102374400/102374386/0f35f4f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms, Non Smoking | Living area | 42-inch Smart TV with digital channels, Netflix, Hulu](https://images.trvl-media.com/lodging/103000000/102380000/102374400/102374386/340ade50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TWO Stunning Nulu CozySuites [](https://www.expedia.co.uk/Louisville-Hotels-TWO-Stunning-Nulu-CozySuites.h102374386.Hotel-Information) Downtown Louisville [](https://www.expedia.co.uk/Louisville-Hotels-TWO-Stunning-Nulu-CozySuites.h102374386.Hotel-Information) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/1000000/430000/427600/427527/a05fd67f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/430000/427600/427527/fa2a33fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/430000/427600/427527/a50f3b3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/430000/427600/427527/f2f02b29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hawthorn Suites by Wyndham Louisville North [](https://www.expedia.co.uk/Louisville-Hotels-Hawthorn-Suites-By-Wyndham-Louisville-North.h427527.Hotel-Information) Jeffersonville 7.4/10 Good (944 reviews) "I would say that the hotel is in pretty good shape. The rooms are very nice. The parking lot however had a ton of people just hanging out. It made it a bit uncomfortable" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) alexis [](https://www.expedia.co.uk/Louisville-Hotels-Hawthorn-Suites-By-Wyndham-Louisville-North.h427527.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Southeastern-Indiana-Hotels.s40-0-d6233889.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Southeastern-Indiana-Hotels.s40-0-d6233889.Travel-Guide-Filter-Hotels) ## Learn more about Southeastern Indiana Explore lots to see and do in Southeastern Indiana—live music, sports teams and sights from Deam Lake State Recreation Area to Huber’s Orchard, Winery & Vineyards. [See all hotels in Southeastern Indiana](https://www.expedia.co.uk/Hotel-Search?startDate=2026-01-25&endDate=2026-01-26&adults=2®ionId=6233889) ![Bathe in the forest...find this on the roof of the outdoor shower house down the hill from the guest house.](https://images.trvl-media.com/place/553248635989202622/88a60920-d501-4b4d-b386-caf78a7f4191.jpg?impolicy=fcrop&w=900&h=675&p=1&q=high) Photo by Serendipity Trip ## Top Southeastern Indiana Hotel Reviews ## Find out more about Southeastern Indiana ## Frequently asked questions ### What are the best 4-star hotels in Southeastern Indiana? ### How much does it cost to stay in a 4-star hotel in Southeastern Indiana? > - Search for the lowest price from £75 ### What's the difference between 5-star and 4-star hotels in Southeastern Indiana? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Cottages in Ohio River Valley ](https://www.expedia.co.uk/Ohio-River-Valley-Cottages.d6233674-aaCottages.Travel-Guide-Accommodation) - 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