A modern glass building with a curved facade and a sign reading "The Kentucky Center".

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Check availability on Southern Indiana Luxury Hotels

Our top choices for Southern Indiana luxury hotels

The Grady

The Grady
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,015 reviews)
The price is £145
includes taxes & fees
2 Aug - 3 Aug
The Grady

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville
9.6 out of 10, Exceptional, (483 reviews)
The price is £177
includes taxes & fees
2 Aug - 3 Aug
Hotel Distil, Autograph Collection

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,281 reviews)
  • cleanliness
    Elegantly designed spaces and refined comforts define this historic Louisville hotel offering a boutique feel in the city centre.
The price is £135
includes taxes & fees
4 Aug - 5 Aug
The Brown Hotel

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,991 reviews)
The price is £138
includes taxes & fees
2 Aug - 3 Aug
Omni Louisville Hotel

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,000 reviews)
  • cleanliness
    Museum-infused luxury awaits at this hotel with spa, restaurant, and contemporary art steps from the river.
The price is £145
includes taxes & fees
5 Aug - 6 Aug
21c Museum Hotel Louisville

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (127 reviews)
The price is £153
includes taxes & fees
16 Aug - 17 Aug
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1,000 reviews)
  • cleanliness
    Historic elegance meets modern luxury city centre, with pillowtop beds, designer toiletries, and 24-hour service.
The price is £142
includes taxes & fees
27 Jul - 28 Jul
Seelbach Hilton Louisville Downtown

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,000 reviews)
The price is £146
includes taxes & fees
16 Aug - 17 Aug
Louisville Marriott Downtown

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (4,175 reviews)
  • cleanliness
    Upscale riverside hotel features panoramic views, spa services, and gourmet dining in city centre Louisville.
The price is £140
includes taxes & fees
3 Aug - 4 Aug
Galt House Hotel Trademark Collection by Wyndham

stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
4.0 star property
Clarksville
9.8 out of 10, Exceptional, (53 reviews)
The price is £143
includes taxes & fees
19 Jul - 20 Jul
stayAPT Suites Louisville North-Clarksville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Southern Indiana

Southern Indianaand its attractions for luxury travelers

Southern Indiana offers a blend of natural beauty and refined experiences perfect for luxury travellers. Start your journey in the charming town of French Lick, home to the historic French Lick Springs Hotel, where you can indulge in a pampering spa day or tee off at their championship golf course. Just a short drive away, the stunning Hoosier National Forest beckons with its expansive trails and serene landscapes, ideal for a leisurely hike or a private picnic amidst nature. For a taste of local culture, the town of Bloomington boasts a vibrant arts scene, with the renowned Indiana University offering theatre performances and art exhibits that cater to sophisticated tastes. Wine enthusiasts will delight in the picturesque wineries along the Indiana Uplands Wine Trail, where guided tastings can elevate your palate while you soak in the lush vineyard views. Finally, consider a stay in the upscale accommodations of Evansville, where riverfront hotels provide luxurious amenities and easy access to the scenic Ohio River, perfect for romantic evening strolls. Southern Indiana harmoniously blends adventure with comfort, making it an exciting choice for travellers seeking memorable luxury experiences.

Top Southern Indiana Hotel Reviews