Title: TOP Historic Hotels in Ohio River Valley for 2025 | Expedia.co.uk [Ohio River Valley Travel Guide](https://expedia.co.uk/Ohio-River-Valley.dx6233674)[Hotels in Ohio River Valley](https://expedia.co.uk/Ohio-River-Valley-Hotels.d6233674.Travel-Guide-Hotels)[Holiday Rentals in Ohio River Valley](https://expedia.co.uk/Ohio-River-Valley-Holiday-Rentals.d6233674.Travel-Guide-HolidayRentals)[Flights to Ohio River Valley](https://expedia.co.uk/Cheap-Flights-To-Ohio-River-Valley.d6233674.Travel-Guide-Flights)[Ohio River Valley Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Ohio-River-Valley.d6233674.Car-Hire-Guide)[Ohio River Valley Holidays](https://expedia.co.uk/Ohio-River-Valley.d6233674.Holidays-City-Breaks) ![Indianapolis featuring autumn colours and a cemetery](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/25000/25344-Indianapolis.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Historic Hotels in Ohio River Valley ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Ohio River Valley Historic Hotels Tonight [10 Oct - 11 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6233674&startDate=2025-10-10&endDate=2025-10-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [11 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6233674&startDate=2025-10-11&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6233674&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6233674&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Ohio River Valley Historic Hotels ![Exterior](https://images.trvl-media.com/lodging/13000000/12560000/12552800/12552757/380612f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/13000000/12560000/12552800/12552757/84bc2f36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/13000000/12560000/12552800/12552757/bf3651e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/13000000/12560000/12552800/12552757/7a04a28c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Louisville Downtown by IHG Downtown Louisville 8.8/10 Excellent (1575) "Super nice hotel, great breakfast, good location to downtown " £68 includes taxes & fees 9 Nov - 10 Nov [](https://www.expedia.co.uk/Louisville-Hotels-Holiday-Inn-Express-Suites-Louisville-Downtown.h12552757.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/20000000/19430000/19425400/19425356/84828b99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/20000000/19430000/19425400/19425356/1f7e8c72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room | 1 bedroom, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/20000000/19430000/19425400/19425356/fa11b632.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/20000000/19430000/19425400/19425356/a7e7693c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Sherman Inn Batesville 9.2/10 Wonderful (148) "Friendly staff and very nice accommodations. " £90 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/Greensburg-Hotels-The-Sherman.h19425356.Hotel-Information) ![Deluxe Apartment, 1 Bedroom, Non Smoking | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/116000000/115640000/115637200/115637139/b5de9d62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/116000000/115640000/115637200/115637139/15680b51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![52-inch Smart TV with digital channels, Netflix, Hulu](https://images.trvl-media.com/lodging/116000000/115640000/115637200/115637139/c6b96389.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 1 Bedroom, Non Smoking | 2 bedrooms, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/116000000/115640000/115637200/115637139/70015996.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### CozySuites - Sky Central Downtown Cincinnati 7.6/10 Good (5) "The check-in process was not user friendly. The sidewalk in front of the property was torn up and had construction tape all around it. We had to wait for 30 minutes or so outside the place before we could get the check in information to be able to get into our room." £165 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/Cincinnati-Hotels-CozySuites-Sky-Central.h115637139.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/a9b7038a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/cef338e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/864ff441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/22b7d23e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 21c Museum Hotel Louisville Downtown Louisville 9.4/10 Exceptional (1004) "Great stay overall. " £145 includes taxes & fees 31 Oct - 1 Nov [](https://www.expedia.co.uk/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information) ![Suite, 1 King Bed, River View | 1 bedroom, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/77000000/76230000/76226500/76226426/73b88cd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/77000000/76230000/76226500/76226426/d3bb4faa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/77000000/76230000/76226500/76226426/22cb620f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/77000000/76230000/76226500/76226426/2cfba2ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Evansville Downtown by IHG Downtown Evansville 8.8/10 Excellent (234) "Nice hotel very clean, close and walkable to restaurants and walk along river" £79 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Evansville-Hotels-Holiday-Inn-Express-Evansville-Downtown.h76226426.Hotel-Information) ![Luxury Room | Premium bedding, down duvets, individually decorated](https://images.trvl-media.com/lodging/94000000/93090000/93082900/93082881/8a800e75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/94000000/93090000/93082900/93082881/d495ea0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/94000000/93090000/93082900/93082881/921df296.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/94000000/93090000/93082900/93082881/9be9137c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Chandler Hotel Madison 10/10 Exceptional (110) "Delightful place and the accommodations were excellent!" £138 includes taxes & fees 10 Nov - 11 Nov [](https://www.expedia.co.uk/Madison-Hotels-The-Chandler-Hotel.h93082881.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/840e31de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/3c2671ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/2a2a7fb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/4fd8456f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Brown Hotel Downtown Louisville 9.4/10 Exceptional (1085) "The hotel and the staff were great." [](https://www.expedia.co.uk/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1870000/1868900/1868803/699e3988.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1870000/1868900/1868803/fb50516c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1870000/1868900/1868803/3780b6ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/2000000/1870000/1868900/1868803/41f3474a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Granville Inn Granville 9.6/10 Exceptional (716) "Best dinner in town" £185 includes taxes & fees 9 Nov - 10 Nov [](https://www.expedia.co.uk/Zanesville-Hotels-Granville-Inn.h1868803.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/108000000/107720000/107715200/107715184/1867b4d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/108000000/107720000/107715200/107715184/32b4db56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Suite | 1 bedroom, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/108000000/107720000/107715200/107715184/74dfd485.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/108000000/107720000/107715200/107715184/32d92eb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Delegate Frankfort 9.2/10 Wonderful (237) "Wonderful place! Definitely will stay here again!" £101 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/Lexington-Hotels-The-Delegate.h107715184.Hotel-Information) ![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/3000000/2820000/2815800/2815760/38970b72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2820000/2815800/2815760/e941ce40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/3000000/2820000/2815800/2815760/f6d39eb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/3000000/2820000/2815800/2815760/2d253a3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Indianapolis Downtown Downtown Indianapolis 9.0/10 Wonderful (1031) "Enjoyed out stay. Great location. Would stay here again. " £121 includes taxes & fees 17 Oct - 18 Oct [](https://www.expedia.co.uk/Indianapolis-Hotels-Courtyard-By-Marriott-Indianapolis-Downtown.h2815760.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-24&endDate=2025-10-25®ionId=6233674&adults=2&specialized_stays_group_explore=historic_property&sort=RECOMMENDED&openPlayBack=true) ## Top Ohio River Valley Hotel Reviews ![Sheraton Indianapolis Hotel at Keystone Crossing](//images.trvl-media.com/lodging/1000000/20000/14900/14838/e72753e3_y.jpg) ### Sheraton Indianapolis Hotel at Keystone Crossing 10/10 Excellent "Deal and nice location " [](https://expedia.co.uk/Indianapolis-Hotels-Sheraton-Indianapolis-Hotel-At-Keystone-Crossing.h14838.Hotel-Information) ![Ironworks Hotel Indy](//images.trvl-media.com/lodging/20000000/19300000/19294100/19294032/02753ebe_y.jpg) ### Ironworks Hotel Indy 10/10 Excellent "Rooms are beautiful and clean. Easy self parking or you can valet. Also dog friendly which is such a plus! Front desk was very helpful in getting us ice and helping with a snafu with room service. Will be coming back!" [](https://expedia.co.uk/Indianapolis-Hotels-Ironworks-Hotel-Indy.h19294032.Hotel-Information) ![Hyatt Regency Cincinnati](//images.trvl-media.com/lodging/1000000/20000/18700/18646/1ec5d305_y.jpg) ### Hyatt Regency Cincinnati 10/10 Excellent "Easy walk to the football stadium!!!" [](https://expedia.co.uk/Cincinnati-Hotels-Hyatt-Regency-Cincinnati.h18646.Hotel-Information) ![Galt House Hotel Trademark Collection by Wyndham](//images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f_y.jpg) ### Galt House Hotel Trademark Collection by Wyndham 10/10 Excellent "Beautiful room & clean facilites. Nice dining nearby." [](https://expedia.co.uk/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) ![Hilton Columbus Downtown](//images.trvl-media.com/lodging/6000000/5280000/5270400/5270320/6a2e3c37_y.jpg) ### Hilton Columbus Downtown 10/10 Excellent "Clean, beautiful lobby, and room. Room was quiet, we could not hear neighbors or even people walking in the hallway. Perfect size for a couple on a weekend getaway." [](https://expedia.co.uk/Columbus-Hotels-Hilton-Columbus-Downtown.h5270320.Hotel-Information) ![Omni Severin Hotel](//images.trvl-media.com/lodging/1000000/20000/17700/17640/3e6b70fc_y.jpg) ### Omni Severin Hotel 10/10 Excellent "Great place! So close to stadium. We had a great time " [](https://expedia.co.uk/Indianapolis-Hotels-Omni-Severin-Hotel.h17640.Hotel-Information) ![Radisson Hotel Cincinnati Riverfront](//images.trvl-media.com/lodging/1000000/10000/2800/2755/68cff2fd_y.jpg) ### Radisson Hotel Cincinnati Riverfront 10/10 Excellent "Clean floors, hallway, throughout the hotel. Pool was open late. Friendly staff" [](https://expedia.co.uk/Cincinnati-Hotels-Radisson-Hotel-Cincinnati-Riverfront.h2755.Hotel-Information) ![Hilton Cincinnati Netherland Plaza](//images.trvl-media.com/lodging/1000000/10000/5900/5818/3a03c8ac_y.jpg) ### Hilton Cincinnati Netherland Plaza 10/10 Excellent "Very nice hotel in good location. Friendly staff and nice bar and restaurant " [](https://expedia.co.uk/Cincinnati-Hotels-Hilton-Cincinnati-Netherland-Plaza.h5818.Hotel-Information) ![Courtyard by Marriott Indianapolis Downtown](//images.trvl-media.com/lodging/3000000/2820000/2815800/2815760/38970b72_y.jpg) ### Courtyard by Marriott Indianapolis Downtown 10/10 Excellent "Everything is absolutely perfect at this location " [](https://expedia.co.uk/Indianapolis-Hotels-Courtyard-By-Marriott-Indianapolis-Downtown.h2815760.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Other - More ways to book - [1 Star Hotels in Historic Route 66](https://www.expedia.co.uk/1Star-Historic-Route-66-Hotels.s10-0-d702654640613646336.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Historic Route 66](https://www.expedia.co.uk/2Star-Historic-Route-66-Hotels.s20-0-d702654640613646336.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Historic Route 66](https://www.expedia.co.uk/3Star-Historic-Route-66-Hotels.s30-0-d702654640613646336.Travel-Guide-Filter-Hotels) - 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