
Compare and book 4 Star hotels in South Carolina Midlands, South Carolina
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check availability on South Carolina Midlands 4 Star Hotels
Our top choices for South Carolina Midlands 4-star hotels

1. Graduate by Hilton Columbia SC
Graduate by Hilton Columbia SCDowntown Columbia
9.4 out of 10, Exceptional, (1,003 reviews)
The price is £102
includes taxes & fees
25 Nov - 26 Nov

2. The Lantern Hotel Columbia
The Lantern Hotel ColumbiaDowntown Columbia
9.8 out of 10, Exceptional, (232 reviews)
The price is £116
includes taxes & fees
15 Nov - 16 Nov

3. Doubletree by Hilton Columbia, SC
Doubletree by Hilton Columbia, SCSeven Oaks
8.0 out of 10, Very good, (1,002 reviews)
The price is £74
includes taxes & fees
15 Nov - 16 Nov

5. Wyndham Vacation Resorts Lake Marion
Wyndham Vacation Resorts Lake MarionSantee
9.4 out of 10, Exceptional, (24 reviews)

6. Columbia Vacation Rental - Walk to Uofsc Campus!
Columbia Vacation Rental - Walk to Uofsc Campus!Downtown Columbia

7. Burrell and Flynn's Farm
Burrell and Flynn's FarmAiken
10.0 out of 10, Exceptional, (5 reviews)
The price is £301
includes taxes & fees
22 Nov - 23 Nov

8. Easy Access to I-77 & I-20: Columbia Duplex!
Easy Access to I-77 & I-20: Columbia Duplex!Columbia
9.4 out of 10, Exceptional, (3 reviews)

9. 2 Mi to SC State & Claflin: Townhome w/ Patio!
2 Mi to SC State & Claflin: Townhome w/ Patio!Orangeburg
Save an average of 15% on thousands of hotels when you're signed in
Learn more about South Carolina Midlands
With Revolutionary War sites, a charming capital city and lots of kayaking opportunities, this southern region is sure to delight.

Top South Carolina Midlands Hotel Reviews
Find out more about South Carolina Midlands
Frequently asked questions
Explore a world of travel with Expedia
- 5 Star Hotels in Lexington
- Cayce Hotels
- Baymont by Wyndham Columbia Northwest
- Charming Spacious 4
- Graduate by Hilton Columbia SC
- Hampton Inn Columbia
- Holiday Inn Columbia
- Holiday Inn & Suites Columbia NE
- Holiday Inn Express Columbia NE
- Hotels with Early Check-in in Columbia
- Hyatt Place Columbia/Harbison
- Lakeside Oasis
- Luxury Hotels in Columbia
- Mainstay Suites Columbia Harbison
- The cozy little heaven of Columbia
- The Rose Door Retreat w/ Huge King Bedroom Suite
- The Tiki Suite
- Wingate by Wyndham Columbia/Fort Jackson
- Columbia Hotels
- Adults Only Resorts & in South Carolina
- Sports Hotels in South Carolina
- All-Inclusive Hotels in South Carolina
- Beach Resorts & in South Carolina
- Cheap Hotels in South Carolina
- Family-Friendly Hotels in South Carolina
- Green Hotels in South Carolina
- Luxury Hotels in South Carolina
- Marina Hotels in South Carolina
- Mountain Hotels in South Carolina
- South Carolina Hotels
- Downtown Columbia Hotels
- Motel 6 Lugoff
- Rustic Waterfront Cabin Lake Wateree
- Farmstay in South Carolina
- Cabin Rentals in South Carolina
- Capsule Hotels in South Carolina
- Caravan Parks in South Carolina
- Chalets in South Carolina
- Studio 6 West Columbia
- Flights to Columbia
- Flights to South Carolina Midlands
- Flights to West Columbia
- Flights to South Carolina
- Flights from Columbia Metropolitan
- Flights from South Carolina
- Flights from Elgin
- Flights from Columbia
- Flights from Atlanta (ATL) to Columbia (CAE)
- Flights from Belfast (BFS) to Columbia (CAE)
- Flights from Birmingham (BHM) to Columbia (CAE)
- Flights from Birmingham (BHX) to Columbia (CAE)
- Flights from Bournemouth (BOH) to Columbia (CAE)
- Flights from Boston (BOS) to Columbia (CAE)
- Flights from Bristol (BRS) to Columbia (CAE)
- Flights from Baltimore (BWI) to Columbia (CAE)
- Flights from Charleston (CHS) to Columbia (CAE)
- Flights from Charlotte (CLT) to Columbia (CAE)
- Flights from Washington (DCA) to Columbia (CAE)
- Flights from Dublin (DUB) to Columbia (CAE)
- Flights from Edinburgh (EDI) to Columbia (CAE)
- Flights from Tortola (EIS) to Columbia (CAE)
- Flights from Glasgow (GLA) to Columbia (CAE)
- Flights from New York (JFK) to Columbia (CAE)
- Flights from Las Vegas (LAS) to Columbia (CAE)
- Flights from Los Angeles (LAX) to Columbia (CAE)
- Flights from London (LGW) to Columbia (CAE)
- Flights from London (LHR) to Columbia (CAE)
- Flights from London (LON) to Columbia (CAE)
- Flights from Manchester (MAN) to Columbia (CAE)
- Flights from Orlando (MCO) to Columbia (CAE)
- Flights from Mexico City (MEX) to Columbia (CAE)
- Flights from Miami (MIA) to Columbia (CAE)
- Flights from Newcastle (NCL) to Columbia (CAE)
- Flights from Newquay (NQY) to Columbia (CAE)
- Flights from Norwich (NWI) to Columbia (CAE)
- Flights from Chicago (ORD) to Columbia (CAE)
- Flights from Philadelphia (PHL) to Columbia (CAE)
- Flights from Seattle (SEA) to Columbia (CAE)
- Flights from San Francisco (SFO) to Columbia (CAE)
- Flights from Toronto (YYZ) to Columbia (CAE)







































