£188 Cheap Flights from Quito (UIO) to Santiago (SCL)

View £188 flight on Fri, 29 May 2026Opens in a new window

Flight 1

Popular airlines from Mariscal Sucre Intl. Airport (UIO) to Santiago Intl. Airport (SCL)

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Cheap Flights from Quito (UIO) to Santiago (SCL)

Prices were available within the past 7 days and start at £188 for one-way flights and £329 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Sat, 27 Jun - Thu, 9 Jul
UIO
Quito
SCL
Santiago
£329 Return, found 6 days ago
£329
Return
found 6 days ago
Select LATAM Airlines Group flight, departing Sat, 27 Jun from Quito to Santiago, returning Thu, 9 Jul, priced at £329 found 6 days ago
LATAM Airlines Group
Tue, 7 Jul - Thu, 9 Jul
UIO
Quito
SCL
Santiago
£337 Return, found 6 days ago
£337
Return
found 6 days ago
Select LATAM Airlines Group flight, departing Tue, 7 Jul from Quito to Santiago, returning Thu, 9 Jul, priced at £337 found 6 days ago
LATAM Airlines Group
Sat, 27 Jun - Tue, 30 Jun
UIO
Quito
SCL
Santiago
£343 Return, found 6 days ago
£343
Return
found 6 days ago
Select LATAM Airlines Group flight, departing Sat, 27 Jun from Quito to Santiago, returning Tue, 30 Jun, priced at £343 found 6 days ago
LATAM Airlines Group
Fri, 19 Jun - Tue, 30 Jun
UIO
Quito
SCL
Santiago
£351 Return, found 6 days ago
£351
Return
found 6 days ago
Select LATAM Airlines Group flight, departing Fri, 19 Jun from Quito to Santiago, returning Tue, 30 Jun, priced at £351 found 6 days ago
LATAM Airlines Group
Fri, 5 Jun - Fri, 12 Jun
UIO
Quito
SCL
Santiago
£367 Return, found 6 days ago
£367
Return
found 6 days ago
Select LATAM Airlines Group flight, departing Fri, 5 Jun from Quito to Santiago, returning Fri, 12 Jun, priced at £367 found 6 days ago
LATAM Airlines Group
Fri, 5 Jun - Fri, 12 Jun
UIO
Quito
SCL
Santiago
£371 Return, found 6 days ago
£371
Return
found 6 days ago
Select LATAM Airlines Group flight, departing Fri, 5 Jun from Quito to Santiago, returning Fri, 12 Jun, priced at £371 found 6 days ago
Copa
Fri, 5 Jun - Fri, 12 Jun
UIO
Quito
SCL
Santiago
£377 Return, found 6 days ago
£377
Return
found 6 days ago
Select Copa flight, departing Fri, 5 Jun from Quito to Santiago, returning Fri, 12 Jun, priced at £377 found 6 days ago
LATAM Airlines Group
Fri, 5 Jun - Fri, 12 Jun
UIO
Quito
SCL
Santiago
£378 Return, found 6 days ago
£378
Return
found 6 days ago
Select LATAM Airlines Group flight, departing Fri, 5 Jun from Quito to Santiago, returning Fri, 12 Jun, priced at £378 found 6 days ago
Copa
Tue, 2 Jun - Sun, 7 Jun
UIO
Quito
SCL
Santiago
£380 Return, found 6 days ago
£380
Return
found 6 days ago
Select Copa flight, departing Tue, 2 Jun from Quito to Santiago, returning Sun, 7 Jun, priced at £380 found 6 days ago
avianca
Fri, 27 Nov - Mon, 30 Nov
UIO
Quito
SCL
Santiago
£457 Return, found 2 hours ago
£457
Return
found 2 hours ago
Select avianca flight, departing Fri, 27 Nov from Quito to Santiago, returning Mon, 30 Nov, priced at £457 found 2 hours ago

Alternative airports near Santiago

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Arturo Merino Benitez SCL. Cheapest and Closest option available. Average driving time to city centre is 17 minutes. Flights from £438
SCL
Arturo Merino Benitez
CheapestClosest
Average driving time to city centre17 min
Flights from £438

Frequently asked questions

What is the cheapest month to fly from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
May is typically the cheapest month to fly from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez), with average return fares of approximately £412. This is about 12% lower than the average price throughout the year. May often sees lower prices as it falls outside of peak holiday seasons, leading to reduced demand. Other cheap months to fly from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) include September and November.
How do I find cheap flights from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
To find a cheap flight from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The best time to fly from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) is typically May or September. These months offer a great balance, with average return flight prices around £412. While we don't have specific popularity data for this route, these months often provide a good combination of value and availability for travel. This information is based on booking data from the past year.
How many flights per day from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
There are approximately 30 connecting flights per day from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez). Some common connection points include Jose Joaquin de Olmedo Intl. (GYE), Tocumen Intl. (PTY), and Jorge Chavez Intl. (LIM).
What is the earliest flight from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The earliest flight from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) typically departs at approximately 12:00 AM local time, operated by LA. This is a seasonal service active in April. An early departure like this can help maximise your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
You'll find the most flights from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) on a Wednesday, with around 21 flights available. This gives you plenty of options for your travel plans. Major airlines on this route include LATAM Airlines, Avianca, and Copa Airlines. Flight schedules are consistent throughout the week.
What are the most popular departure times for flights from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The most popular departure times for flights from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) are in the evening, from 6pm to 9pm. Approximately 25% of passengers prefer this time window. Many major carriers, including LATAM Airlines, Copa Airlines and Avianca, offer flights during this window. This timing works well because it allows you to finish your day before heading to the airport, and you'll arrive in Santiago at a reasonable hour.
How long does it take to fly from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
A flight from UIO to SCL with a layover takes around 23 hours, with the route covering approximately 2,351 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
Select the "Business class" and "First class" filters when looking for UIO to SCL flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) flight with Expedia?
It's easy to earn miles on a Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Santiago from Mariscal Sucre Intl. (UIO)?
When traveling from Mariscal Sucre Intl. (UIO) to Santiago, you can fly into Arturo Merino Benitez (SCL) and Cibao Intl. (STI). Some flights may connect through major hubs like Jose Joaquin de Olmedo Intl. (GYE), Jorge Chavez Intl. (LIM), El Dorado Intl. (BOG) before reaching Santiago. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) at the last minute?
Typically, booking a last minute flight from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) flight and hotel package?
Securing a Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
If you booked your Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Mariscal Sucre Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Copa, LATAM Airlines Group, avianca
Return price
£328
Distance
3761 km

Book with confidence

Compare flights from Quito to Santiago easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Quito to Santiago. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Arturo Merino Benitez in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Mariscal Sucre Intl. to Arturo Merino Benitez.  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Mariscal Sucre Intl. (UIO) to Arturo Merino Benitez (SCL)

The easiest way to view the best deals on flights from Quito to Santiago today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Mariscal Sucre Intl. to Arturo Merino Benitez start at just £329 and range up to £457.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Quito and Santiago
  • booking your flight during June, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Quito to Santiago flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Mariscal Sucre Intl. to Arturo Merino Benitez for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Quito to Santiago easily and book with confidence

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*Available to Expedia members.