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£149 Cheap Flights from Guayaquil (GYE) to Santiago (SCL)

View £149 flight on Thu, 1 Oct 2026Opens in a new window

Popular airlines from Jose Joaquin de Olmedo Intl. Airport (GYE) to Santiago Intl. Airport (SCL)

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Cheap Flights from Guayaquil (GYE) to Santiago (SCL)

Prices were available within the past 7 days and start at £149 for one-way flights and £295 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Wed, 6 Jan - Sat, 30 Jan
GYE
Guayaquil
SCL
Santiago
£295 Return, found 1 day ago
£295
Return
found 1 day ago
Select avianca flight, departing Wed, 6 Jan from Guayaquil to Santiago, returning Sat, 30 Jan, priced at £295 found 1 day ago
LATAM Airlines Group
Mon, 1 Feb - Sat, 27 Feb
GYE
Guayaquil
SCL
Santiago
£300 Return, found 3 days ago
£300
Return
found 3 days ago
Select LATAM Airlines Group flight, departing Mon, 1 Feb from Guayaquil to Santiago, returning Sat, 27 Feb, priced at £300 found 3 days ago
avianca
Sun, 1 Nov - Fri, 6 Nov
GYE
Guayaquil
SCL
Santiago
£301 Return, found 1 day ago
£301
Return
found 1 day ago
Select avianca flight, departing Sun, 1 Nov from Guayaquil to Santiago, returning Fri, 6 Nov, priced at £301 found 1 day ago
avianca
Mon, 1 Feb - Sat, 27 Feb
GYE
Guayaquil
SCL
Santiago
£304 Return, found 3 days ago
£304
Return
found 3 days ago
Select avianca flight, departing Mon, 1 Feb from Guayaquil to Santiago, returning Sat, 27 Feb, priced at £304 found 3 days ago
LATAM Airlines Group
Mon, 1 Feb - Sat, 27 Feb
GYE
Guayaquil
SCL
Santiago
£305 Return, found 3 days ago
£305
Return
found 3 days ago
Select LATAM Airlines Group flight, departing Mon, 1 Feb from Guayaquil to Santiago, returning Sat, 27 Feb, priced at £305 found 3 days ago
avianca
Sun, 1 Nov - Fri, 6 Nov
GYE
Guayaquil
SCL
Santiago
£308 Return, found 1 day ago
£308
Return
found 1 day ago
Select avianca flight, departing Sun, 1 Nov from Guayaquil to Santiago, returning Fri, 6 Nov, priced at £308 found 1 day ago
avianca
Fri, 21 Aug - Fri, 28 Aug
GYE
Guayaquil
SCL
Santiago
£310 Return, found 5 hours ago
£310
Return
found 5 hours ago
Select avianca flight, departing Fri, 21 Aug from Guayaquil to Santiago, returning Fri, 28 Aug, priced at £310 found 5 hours ago
LATAM Airlines Group
Sun, 15 Nov - Sun, 22 Nov
GYE
Guayaquil
SCL
Santiago
£312 Return, found 4 days ago
£312
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Sun, 15 Nov from Guayaquil to Santiago, returning Sun, 22 Nov, priced at £312 found 4 days ago
LATAM Airlines Group
Thu, 10 Sept - Thu, 17 Sept
GYE
Guayaquil
SCL
Santiago
£315 Return, found 4 days ago
£315
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Thu, 10 Sept from Guayaquil to Santiago, returning Thu, 17 Sept, priced at £315 found 4 days ago
Copa
Thu, 10 Sept - Thu, 17 Sept
GYE
Guayaquil
SCL
Santiago
£385 Return, found 4 days ago
£385
Return
found 4 days ago
Select Copa flight, departing Thu, 10 Sept from Guayaquil to Santiago, returning Thu, 17 Sept, priced at £385 found 4 days ago

Alternative airports near Santiago

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Arturo Merino Benitez SCL. Cheapest and Closest option available. Average driving time to city centre is 17 minutes. Flights from £301
SCL
Arturo Merino Benitez
CheapestClosest
Average driving time to city centre17 min
Flights from £301

Find the cheapest month to fly from Guayaquil (GYE) to Santiago (SCL)

September is typically the cheapest month to fly

From £257 - £351 per traveller.

Frequently asked questions

How much does a flight from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez) cost?
You can find one-way and return flights from GYE to SCL with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when GYE to SCL ticket fares go up or down.
What is the cheapest month to fly from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The cheapest months to fly from GYE to SCL are typically during off-peak season when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you are able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Guayaquil (GYE) to Santiago (SCL)?
Enter GYE to SCL and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
LATAM Airlines Group also offers one of the cheapest connecting return flights from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez) starting from around £453. LATAM Airlines Group is one of the cheapest airlines offering nonstop return flights from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez), with tickets starting from around £461 for flights that can be booked for departure within the next year. These prices are per adult for economy/coach class. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
How do I find cheap flights from Guayaquil (GYE) to Santiago (SCL)?
To find a cheap flight from Guayaquil (GYE) to Santiago (SCL), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Guayaquil (GYE) to Santiago (SCL)?
Sort flights by "Departure (earliest)" on Expedia to find the earliest flight from Guayaquil (GYE) to Santiago (SCL). To compare more early flights, use the "Early Morning" and "Morning" filters in your search.
How long does it take to fly from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
Direct flights from GYE to SCL usually take about 4 hours 50 minutes, traveling roughly 3,602 kilometers. If you opt for a connecting flight, expect to add around 12 hours 30 minutes to your journey. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Guayaquil (GYE) to Santiago (SCL)?
Select the "Business class" and "First class" filters when looking for Guayaquil (GYE) to Santiago (SCL) flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Guayaquil (GYE) to Santiago (SCL) flight with Expedia?
It's easy to earn miles on a Guayaquil (GYE) to Santiago (SCL) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
Is it cheaper to buy a plane ticket from Guayaquil (GYE) to Santiago (SCL) at the last minute?
Typically, booking a last minute flight from Guayaquil (GYE) to Santiago (SCL) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Guayaquil (GYE) to Santiago (SCL) flight and hotel package?
Securing a Guayaquil (GYE) to Santiago (SCL) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Guayaquil (GYE) to Santiago (SCL)?
If you booked your Guayaquil (GYE) to Santiago (SCL) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Jose Joaquin de Olmedo Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Copa, LATAM Airlines Group, avianca
Return price
£295
Distance
3580 km
Average flight time
3 hours 51 mins

Book with confidence

Compare flights from Guayaquil to Santiago easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Guayaquil to Santiago. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Arturo Merino Benitez in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Jose Joaquin de Olmedo Intl. to Arturo Merino Benitez.  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Jose Joaquin de Olmedo Intl. (GYE) to Arturo Merino Benitez (SCL)

The easiest way to view the best deals on flights from Guayaquil to Santiago today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Jose Joaquin de Olmedo Intl. to Arturo Merino Benitez start at just £295 and range up to £385.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Guayaquil and Santiago
  • booking your flight during January, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Guayaquil to Santiago flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Jose Joaquin de Olmedo Intl. to Arturo Merino Benitez for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Guayaquil to Santiago easily and book with confidence

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*Available to Expedia members.