£145 Cheap Flights from Guayaquil (GYE) to Santiago (SCL)

View £145 flight on Tue, 9 Jun 2026Opens in a new window

Popular airlines from Jose Joaquin de Olmedo Intl. Airport (GYE) to Santiago Intl. Airport (SCL)

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Cheap Flights from Guayaquil (GYE) to Santiago (SCL)

Prices were available within the past 7 days and start at £145 for one-way flights and £276 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Tue, 16 Jun - Tue, 23 Jun
GYE
Guayaquil
SCL
Santiago
£276 Return, found 2 days ago
£276
Return
found 2 days ago
Select LATAM Airlines Group flight, departing Tue, 16 Jun from Guayaquil to Santiago, returning Tue, 23 Jun, priced at £276 found 2 days ago
LATAM Airlines Group
Tue, 16 Jun - Tue, 23 Jun
GYE
Guayaquil
SCL
Santiago
£334 Return, found 2 days ago
£334
Return
found 2 days ago
Select LATAM Airlines Group flight, departing Tue, 16 Jun from Guayaquil to Santiago, returning Tue, 23 Jun, priced at £334 found 2 days ago
LATAM Airlines Group
Tue, 16 Jun - Tue, 23 Jun
GYE
Guayaquil
SCL
Santiago
£339 Return, found 2 days ago
£339
Return
found 2 days ago
Select LATAM Airlines Group flight, departing Tue, 16 Jun from Guayaquil to Santiago, returning Tue, 23 Jun, priced at £339 found 2 days ago
LATAM Airlines Group
Mon, 8 Jun - Sun, 14 Jun
GYE
Guayaquil
SCL
Santiago
£346 Return, found 4 days ago
£346
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Mon, 8 Jun from Guayaquil to Santiago, returning Sun, 14 Jun, priced at £346 found 4 days ago
LATAM Airlines Group
Mon, 8 Jun - Sun, 14 Jun
GYE
Guayaquil
SCL
Santiago
£352 Return, found 4 days ago
£352
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Mon, 8 Jun from Guayaquil to Santiago, returning Sun, 14 Jun, priced at £352 found 4 days ago
LATAM Airlines Group
Mon, 8 Jun - Sun, 14 Jun
GYE
Guayaquil
SCL
Santiago
£357 Return, found 4 days ago
£357
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Mon, 8 Jun from Guayaquil to Santiago, returning Sun, 14 Jun, priced at £357 found 4 days ago
Copa
Sun, 24 May - Thu, 28 May
GYE
Guayaquil
SCL
Santiago
£357 Return, found 2 days ago
£357
Return
found 2 days ago
Select Copa flight, departing Sun, 24 May from Guayaquil to Santiago, returning Thu, 28 May, priced at £357 found 2 days ago
LATAM Airlines Group
Tue, 16 Jun - Tue, 23 Jun
GYE
Guayaquil
SCL
Santiago
£359 Return, found 2 days ago
£359
Return
found 2 days ago
Select LATAM Airlines Group flight, departing Tue, 16 Jun from Guayaquil to Santiago, returning Tue, 23 Jun, priced at £359 found 2 days ago
Copa
Sun, 24 May - Thu, 28 May
GYE
Guayaquil
SCL
Santiago
£360 Return, found 2 days ago
£360
Return
found 2 days ago
Select Copa flight, departing Sun, 24 May from Guayaquil to Santiago, returning Thu, 28 May, priced at £360 found 2 days ago
avianca
Thu, 23 Jul - Tue, 28 Jul
GYE
Guayaquil
SCL
Santiago
£400 Return, found 15 hours ago
£400
Return
found 15 hours ago
Select avianca flight, departing Thu, 23 Jul from Guayaquil to Santiago, returning Tue, 28 Jul, priced at £400 found 15 hours ago

Alternative airports near Santiago

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Arturo Merino Benitez SCL. Cheapest and Closest option available. Average driving time to city centre is 17 minutes. Flights from £357
SCL
Arturo Merino Benitez
CheapestClosest
Average driving time to city centre17 min
Flights from £357

Frequently asked questions

Which airlines fly direct from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
Enter GYE to SCL and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
To find a cheap flight from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The best airline to fly with from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez) will differ from traveller to traveller. If you like to fly early, LA offers early morning flights. If price is the most important factor, LA typically offers the lowest fares. LA offers the most daily flights from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez), which is brilliant if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
There is approximately 1 nonstop flight per day from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez). For even more choice, look at flights that include layovers, as there are around 26 connecting flights per day. Some common connection points include Mariscal Sucre Intl. (UIO), Tocumen Intl. (PTY), and Jorge Chavez Intl. (LIM).
What is the earliest flight from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The earliest flight from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez) typically departs at approximately 3:30 AM local time, operated by Avianca. This service operates year-round, making it a consistent option for your travel plans. An early departure like this can help you maximise your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
You'll typically find the most flights from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez) on a Sunday, with around 16 flights available. This gives you a good selection of options for your travel plans. Major airlines on this route include AV, CM, and LA. Flight schedules are consistent throughout the week.
What are the most popular departure times for flights from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The most popular departure times for flights from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez) are in the afternoon, from 3pm to 6pm. About 23% of passengers prefer this time window. Many major carriers, including LATAM Airlines and Avianca, offer flights during this window. This timing works well because it allows you to have a productive morning before your flight and arrive in Santiago in the evening.
How long does it take to fly from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
A nonstop flight from GYE to SCL typically takes around 4 hours 50 minutes, covering approximately 2,238 miles. Connecting flights on this route usually add 14 hours to your travel time. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
Select the "Business class" and "First class" filters when looking for GYE to SCL flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez) flight with Expedia?
It's easy to earn miles on a Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Santiago from Jose Joaquin de Olmedo Intl. (GYE)?
When traveling from Jose Joaquin de Olmedo Intl. (GYE) to Santiago, you can fly into Cibao Intl. (STI) and Arturo Merino Benitez (SCL). Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez) at the last minute?
Typically, booking a last minute flight from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez) flight and hotel package?
Securing a Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
If you booked your Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Jose Joaquin de Olmedo Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Copa, LATAM Airlines Group, avianca
Return price
£275
Distance
3580 km
Average flight time
4 hours 51 mins

Book with confidence

Compare flights from Guayaquil to Santiago easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Guayaquil to Santiago. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Arturo Merino Benitez in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Jose Joaquin de Olmedo Intl. to Arturo Merino Benitez.  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Jose Joaquin de Olmedo Intl. (GYE) to Arturo Merino Benitez (SCL)

The easiest way to view the best deals on flights from Guayaquil to Santiago today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Jose Joaquin de Olmedo Intl. to Arturo Merino Benitez start at just £276 and range up to £400.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Guayaquil and Santiago
  • booking your flight during June, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Guayaquil to Santiago flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Jose Joaquin de Olmedo Intl. to Arturo Merino Benitez for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Guayaquil to Santiago easily and book with confidence

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