£352 Cheap Flights from San Francisco (SFO) to Santiago (SCL)

View £352 flight on Tue, 6 Oct 2026Opens in a new window

Popular airlines from San Francisco International Airport (SFO) to Santiago Intl. Airport (SCL)

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Cheap Flights from San Francisco (SFO) to Santiago (SCL)

Prices were available within the past 7 days and start at £352 for one-way flights and £577 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, 2 Jan - Mon, 11 Jan
SFO
San Francisco
SCL
Santiago
£577 Return, found 1 day ago
£577
Return
found 1 day ago
Select American Airlines flight, departing Sat, 2 Jan from San Francisco to Santiago, returning Mon, 11 Jan, priced at £577 found 1 day ago
Alaska Airlines
Wed, 9 Sept - Wed, 16 Sept
SFO
San Francisco
SCL
Santiago
£597 Return, found 10 hours ago
£597
Return
found 10 hours ago
Select Alaska Airlines flight, departing Wed, 9 Sept from San Francisco to Santiago, returning Wed, 16 Sept, priced at £597 found 10 hours ago
LATAM Airlines Group
Wed, 9 Sept - Wed, 16 Sept
SFO
San Francisco
SCL
Santiago
£602 Return, found 10 hours ago
£602
Return
found 10 hours ago
Select LATAM Airlines Group flight, departing Wed, 9 Sept from San Francisco to Santiago, returning Wed, 16 Sept, priced at £602 found 10 hours ago
LATAM Airlines Group
Wed, 9 Sept - Wed, 16 Sept
SFO
San Francisco
SCL
Santiago
£605 Return, found 10 hours ago
£605
Return
found 10 hours ago
Select LATAM Airlines Group flight, departing Wed, 9 Sept from San Francisco to Santiago, returning Wed, 16 Sept, priced at £605 found 10 hours ago
LATAM Airlines Group
Wed, 9 Sept - Wed, 16 Sept
SFO
San Francisco
SCL
Santiago
£610 Return, found 10 hours ago
£610
Return
found 10 hours ago
Select LATAM Airlines Group flight, departing Wed, 9 Sept from San Francisco to Santiago, returning Wed, 16 Sept, priced at £610 found 10 hours ago
avianca
Wed, 9 Sept - Wed, 16 Sept
SFO
San Francisco
SCL
Santiago
£625 Return, found 10 hours ago
£625
Return
found 10 hours ago
Select avianca flight, departing Wed, 9 Sept from San Francisco to Santiago, returning Wed, 16 Sept, priced at £625 found 10 hours ago
avianca
Wed, 9 Sept - Wed, 16 Sept
SFO
San Francisco
SCL
Santiago
£633 Return, found 10 hours ago
£633
Return
found 10 hours ago
Select avianca flight, departing Wed, 9 Sept from San Francisco to Santiago, returning Wed, 16 Sept, priced at £633 found 10 hours ago
avianca
Wed, 9 Sept - Wed, 16 Sept
SFO
San Francisco
SCL
Santiago
£638 Return, found 10 hours ago
£638
Return
found 10 hours ago
Select avianca flight, departing Wed, 9 Sept from San Francisco to Santiago, returning Wed, 16 Sept, priced at £638 found 10 hours ago
avianca
Wed, 9 Sept - Wed, 16 Sept
SFO
San Francisco
SCL
Santiago
£640 Return, found 10 hours ago
£640
Return
found 10 hours ago
Select avianca flight, departing Wed, 9 Sept from San Francisco to Santiago, returning Wed, 16 Sept, priced at £640 found 10 hours ago
Copa
Wed, 9 Sept - Wed, 16 Sept
SFO
San Francisco
SCL
Santiago
£649 Return, found 10 hours ago
£649
Return
found 10 hours ago
Select Copa flight, departing Wed, 9 Sept from San Francisco to Santiago, returning Wed, 16 Sept, priced at £649 found 10 hours ago

Find the cheapest month to fly from San Francisco (SFO) to Santiago (SCL)

November is typically the cheapest month to fly

From £511 - £691 per traveller.

Frequently asked questions

How much is a flight from San Francisco Intl. Airport (SFO) to SCL?
Within the past 7 days on Expedia, for flights departing within the next year, the lowest price quoted for a round-trip flight between San Francisco Intl. Airport (SFO) and Nuevo Pudahuel Airport was £577. Cheap tickets don't hang around forever, so make sure you book yours today. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from San Francisco Intl. Airport (SFO) to Santiago International Airport?
Every air carrier has its own set of terms and conditions. If you do decide to cancel, follow the simple instructions on our Customer Service Portal.
How do I find cheap flights from San Francisco Airport to Santiago International Airport that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for San Francisco Airport to Nuevo Pudahuel Airport flights, you'll see a "no change fees" filter for you to select.
How far is the flight from SFO to Santiago International Airport?
The distance is around 9,500 kilometres, so pack your carry-on bag with everything you need to make your journey comfortable. Not sure what to take on board your San Francisco to Santiago flight? A sleep mask, earplugs and a travel pillow are among the essentials.
Which airlines fly direct from SFO to SCL?
Unfortunately, there are no airlines that fly directly between SFO and Santiago International Airport. You'll have to book a flight with one or more stops.
Are San Francisco Airport to Arturo Merino Benitez Airport (SCL) flight tickets cheaper when they're purchased at the last minute?
Late planners can occasionally find a bargain, with some super cheap fares from SFO to Santiago International Airport emerging a few weeks prior to the departure date. If you'd rather plan ahead of time, Expedia compares and updates the best flight deals continuously — as early as 12 months in advance in some cases. It does depend on the carrier though, as not all airlines publish prices that far in advance.

Travel information

Origin airport
San Francisco Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Copa, LATAM Airlines Group, avianca
Return price
£577
Distance
9474 km

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