£158 Cheap Flights from Tampa (TPA) to Des Moines (DSM)

View £158 flight on Wed, 29 Jul 2026Opens in a new window

Flight 1

Popular airlines from Tampa Intl. Airport (TPA) to Des Moines International Airport (DSM)

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Cheap Flights from Tampa (TPA) to Des Moines (DSM)

Prices were available within the past 7 days and start at £158 for one-way flights and £315 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, 29 Jul - Wed, 5 Aug
TPA
Tampa
DSM
Des Moines
£315 Return, found 1 day ago
£315
Return
found 1 day ago
Select American Airlines flight, departing Wed, 29 Jul from Tampa to Des Moines, returning Wed, 5 Aug, priced at £315 found 1 day ago
Delta
Wed, 29 Jul - Wed, 5 Aug
TPA
Tampa
DSM
Des Moines
£315 Return, found 1 day ago
£315
Return
found 1 day ago
Select Delta flight, departing Wed, 29 Jul from Tampa to Des Moines, returning Wed, 5 Aug, priced at £315 found 1 day ago
American Airlines
Wed, 29 Jul - Wed, 5 Aug
TPA
Tampa
DSM
Des Moines
£321 Return, found 1 day ago
£321
Return
found 1 day ago
Select American Airlines flight, departing Wed, 29 Jul from Tampa to Des Moines, returning Wed, 5 Aug, priced at £321 found 1 day ago
Delta
Wed, 29 Jul - Wed, 5 Aug
TPA
Tampa
DSM
Des Moines
£322 Return, found 1 day ago
£322
Return
found 1 day ago
Select Delta flight, departing Wed, 29 Jul from Tampa to Des Moines, returning Wed, 5 Aug, priced at £322 found 1 day ago
American Airlines
Wed, 29 Jul - Wed, 5 Aug
TPA
Tampa
DSM
Des Moines
£323 Return, found 1 day ago
£323
Return
found 1 day ago
Select American Airlines flight, departing Wed, 29 Jul from Tampa to Des Moines, returning Wed, 5 Aug, priced at £323 found 1 day ago
American Airlines
Wed, 29 Jul - Wed, 5 Aug
TPA
Tampa
DSM
Des Moines
£324 Return, found 1 day ago
£324
Return
found 1 day ago
Select American Airlines flight, departing Wed, 29 Jul from Tampa to Des Moines, returning Wed, 5 Aug, priced at £324 found 1 day ago
Delta
Wed, 29 Jul - Wed, 5 Aug
TPA
Tampa
DSM
Des Moines
£330 Return, found 1 day ago
£330
Return
found 1 day ago
Select Delta flight, departing Wed, 29 Jul from Tampa to Des Moines, returning Wed, 5 Aug, priced at £330 found 1 day ago
American Airlines
Wed, 29 Jul - Wed, 5 Aug
TPA
Tampa
DSM
Des Moines
£332 Return, found 1 day ago
£332
Return
found 1 day ago
Select American Airlines flight, departing Wed, 29 Jul from Tampa to Des Moines, returning Wed, 5 Aug, priced at £332 found 1 day ago
American Airlines
Wed, 29 Jul - Wed, 5 Aug
TPA
Tampa
DSM
Des Moines
£333 Return, found 1 day ago
£333
Return
found 1 day ago
Select American Airlines flight, departing Wed, 29 Jul from Tampa to Des Moines, returning Wed, 5 Aug, priced at £333 found 1 day ago
United
Wed, 29 Jul - Wed, 5 Aug
TPA
Tampa
DSM
Des Moines
£381 Return, found 1 day ago
£381
Return
found 1 day ago
Select United flight, departing Wed, 29 Jul from Tampa to Des Moines, returning Wed, 5 Aug, priced at £381 found 1 day ago

Frequently asked questions

What is the cheapest month to fly from Tampa, FL (TPA-Tampa Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
August is typically the cheapest month to fly from Tampa, FL (TPA-Tampa Intl.) to Des Moines, IA (DSM-Des Moines Intl.), with average return fares of approximately £276. This is about 17% lower than the average price throughout the year. August often sees lower prices as the peak summer travel season winds down, leading to reduced demand. Other cheap months to fly from Tampa, FL (TPA-Tampa Intl.) to Des Moines, IA (DSM-Des Moines Intl.) include January and September.
How do I find cheap flights from Tampa, FL (TPA-Tampa Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
To find a cheap flight from Tampa, FL (TPA-Tampa Intl.) to Des Moines, IA (DSM-Des Moines Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Tampa, FL (TPA-Tampa Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
Based on booking data from the past year, the cheapest months to fly from Tampa, FL (TPA-Tampa Intl.) to Des Moines, IA (DSM-Des Moines Intl.) are typically August and January, with average return flight prices around £276. These months often fall outside of peak travel seasons, which can help you find more affordable fares.
How many flights per day from Tampa, FL (TPA-Tampa Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
There are approximately 95 connecting flights per day from Tampa Intl. (TPA) to Des Moines Intl. (DSM). Some common connection points include Baltimore Washington Intl. Thurgood Marshall (BWI), Hartsfield-Jackson Atlanta Intl. (ATL), and O'Hare Intl. (ORD).
What is the earliest flight from Tampa, FL (TPA-Tampa Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
The earliest flight from Tampa, FL (TPA-Tampa Intl.) to Des Moines, IA (DSM-Des Moines Intl.) typically departs at approximately 5:00 AM local time, operated by American Airlines. This is a seasonal service active in November. An early departure like this can help maximise your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Tampa, FL (TPA-Tampa Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
You'll typically find the most flights from Tampa, FL (TPA-Tampa Intl.) to Des Moines, IA (DSM-Des Moines Intl.) on a Tuesday, with around 50 flights available. This gives you plenty of options for your travel plans. Major airlines on this route include American Airlines, United Airlines, and Delta Air Lines. Flight schedules are consistent throughout the week.
What are the most popular departure times for flights from Tampa, FL (TPA-Tampa Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
The most popular departure times for flights from Tampa, FL (TPA-Tampa Intl.) to Des Moines, IA (DSM-Des Moines Intl.) are in the early morning, between 6am and 9am. About 34% of passengers prefer this time. Many major carriers, including American Airlines, Delta Air Lines and United Airlines, offer flights during this window. This timing works well if you want to get an early start to your travel day and arrive at your destination with plenty of time.
How long does it take to fly from Tampa, FL (TPA-Tampa Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
Flying from TPA to DSM with a connection usually takes about 7 hours 50 minutes, traveling roughly 1,127 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Tampa, FL (TPA-Tampa Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
Select the "Business class" and "First class" filters when looking for TPA to DSM flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Tampa, FL (TPA-Tampa Intl.) to Des Moines, IA (DSM-Des Moines Intl.) flight with Expedia?
It's easy to earn miles on a Tampa, FL (TPA-Tampa Intl.) to Des Moines, IA (DSM-Des Moines Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Des Moines from Tampa Intl. (TPA)?
If you're planning to travel to Des Moines from Tampa Intl. (TPA), you can fly directly into Des Moines Intl. (DSM) Some flights may connect through major hubs like Washington Dulles Intl. (IAD), Charlotte-Douglas Intl. (CLT), George Bush Intercontinental (IAH) before reaching Des Moines. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Tampa, FL (TPA-Tampa Intl.) to Des Moines, IA (DSM-Des Moines Intl.) at the last minute?
Typically, booking a last minute flight from Tampa, FL (TPA-Tampa Intl.) to Des Moines, IA (DSM-Des Moines Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Tampa, FL (TPA-Tampa Intl.) to Des Moines, IA (DSM-Des Moines Intl.) flight and hotel package?
Securing a Tampa, FL (TPA-Tampa Intl.) to Des Moines, IA (DSM-Des Moines Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Tampa, FL (TPA-Tampa Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
If you booked your Tampa, FL (TPA-Tampa Intl.) to Des Moines, IA (DSM-Des Moines Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Tampa Intl.
Destination airport
Des Moines Intl.
Airlines serving
American Airlines, Delta, United
Return price
£314
Distance
1803 km

Book with confidence

Compare flights from Tampa to Des Moines easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Tampa to Des Moines. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Des Moines Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Tampa Intl. to Des Moines Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Tampa Intl. (TPA) to Des Moines Intl. (DSM)

The easiest way to view the best deals on flights from Tampa to Des Moines today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Tampa Intl. to Des Moines Intl. start at just £315 and range up to £381.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Tampa and Des Moines
  • booking your flight during July, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Tampa to Des Moines flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Tampa Intl. to Des Moines Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Tampa to Des Moines easily and book with confidence

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*Available to Expedia members.