Title: £169 Cheap Flights from San Francisco to Des Moines (SFO to DSM) - Expedia.co.uk ![Iowa State Capitol](https://images.trvl-media.com/place/601690/d6e0e2f2-7876-4d18-865a-ae2f68f4627c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/601690/d6e0e2f2-7876-4d18-865a-ae2f68f4627c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £169 Cheap Flights from San Francisco (SFO) to Des Moines (DSM) [View £169 flight on Mon, 15 Dec 2025](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:SFO,to:DSM,departure:15/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:168.20&airProductToken=AQpbCioIwaYBEgE4GLJxIEMo7-X_AjCj6P8COE9AAFgBagJQTXIIT1ZBSVZTTTMKLQjBpgESBDQwMzMYQyDDZCib6f8CMNTq_wI4R0ABWAFqAlBNcghPVkFJVlNNMxIKCAEQARgBKgJBUxgBIgQIARABKAIoAygEMAE) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from San Francisco International Airport (SFO) to Des Moines International Airport (DSM) - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:sfo,to:dsm,departure:14/11/2025TANYT&leg2=from:dsm,to:sfo,departure:21/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![United](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.co.uk/Flights-Search?leg1=from:sfo,to:dsm,departure:14/11/2025TANYT&leg2=from:dsm,to:sfo,departure:21/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) - ![Delta](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg) Delta [](https://www.expedia.co.uk/Flights-Search?leg1=from:sfo,to:dsm,departure:14/11/2025TANYT&leg2=from:dsm,to:sfo,departure:21/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}]) - ![Southwest Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_WN.svg) Southwest Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:sfo,to:dsm,departure:14/11/2025TANYT&leg2=from:dsm,to:sfo,departure:21/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"WN"}}]) - ![Frontier Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_F9.svg) Frontier Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:sfo,to:dsm,departure:14/11/2025TANYT&leg2=from:dsm,to:sfo,departure:21/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"F9"}}]) - ![Alaska Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AS.svg) Alaska Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:sfo,to:dsm,departure:14/11/2025TANYT&leg2=from:dsm,to:sfo,departure:21/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AS"}}]) - ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* - ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap Flights from San Francisco (SFO) to Des Moines (DSM) Prices were available within the past 7 days and start at £169 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ## Find the cheapest month to fly from San Francisco (SFO) to Des Moines (DSM) ### November is typically the cheapest month to fly From £103 - £499 per traveller. ## Frequently asked questions ### How much is a flight from SFO to DSM? > The lowest price advertised for a round-trip flight from San Francisco Airport to Des Moines Intl. Airport is . But you better get a move on. This price is taken from fares available within the last 7 days on Expedia for flights departing within the next year. Prices and availability are subject to change. Additional terms apply. ### Do I need to pay a cancellation fee if I cancel my flight from San Francisco Airport to Des Moines Intl. Airport (DSM)? > The majority of flights can be cancelled online, but whether or not you incur a fee depends on your airline. If you do have to cancel your trip, follow the easy instructions in the [Customer Service Portal](https://www.expedia.co.uk/service/?langid=1033). ### How do I find cheap flights from San Francisco Airport to Des Moines Intl. Airport that have flexible change policies? > Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for SFO to DSM flights, you'll see a "no change fees" filter for you to select. ### How far is the flight from SFO to DSM? > You'll be in the air for a while, as the flight distance between San Francisco and Des Moines is 2,500 kilometres. Create a playlist of your favourite podcasts before leaving home to stay entertained during your flight. ### Which airlines fly direct from San Francisco Airport to Des Moines Intl. Airport? > Flying directly between San Francisco Airport and Des Moines Intl. Airport isn't possible at the moment. However, you'll still be able to book a flight to Des Moines with at least one stop. ### Are SFO to Des Moines Intl. Airport (DSM) flight tickets cheaper when they're purchased at the last minute? > Booking last minute from SFO to Des Moines Intl. Airport (DSM) can be hit-or-miss. You may be able to find a bargain, but you could also miss out entirely! If you'd rather start your travel planning early, Expedia compares flight deals up to a year in advance. Just bear in mind that not all airlines publish their prices so far in advance. Our advice? Check back often as updates are made frequently. ## Travel information | Origin airport | San Francisco Intl. | | --- | --- | | Destination airport | Des Moines Intl. | | Distance | 2474 km | ## Book with confidence ### Compare flights from San Francisco to Des Moines easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from San Francisco to Des Moines. Operating between them flights per day, 3 airlines cover the route. And fly direct, getting you to Des Moines Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from San Francisco Intl. to Des Moines Intl..   To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights.  Grab a great deal on your flight from San Francisco Intl. (SFO) to Des Moines Intl. (DSM) The easiest way to view the best deals on flights from San Francisco to Des Moines today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from San Francisco Intl. to Des Moines Intl. start at just and range up to .   To find an even better deal, try   - being flexible on your dates – midweek flights can be cheaper - looking for other airports near San Francisco and Des Moines - booking your flight during , the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper  Why you should book your San Francisco to Des Moines flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from San Francisco Intl. to Des Moines Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.   Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. 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