£155 Cheap Flights from Detroit (DTW) to Des Moines (DSM)

View £155 flight on Mon, 8 Sep 2025Opens in a new window

Popular airlines from Detroit Metropolitan Wayne County Airport (DTW) to Des Moines International Airport (DSM)

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 25% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap Flights from Detroit (DTW) to Des Moines (DSM)

Prices were available within the past 7 days and start at £155 for one-way flights and £311 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Mon, 8 Sep - Thu, 11 Sep
DTW
Detroit
DSM
Des Moines
£311 Return, just found
£311
Return
just found
Select Delta flight, departing Mon, 8 Sep from Detroit to Des Moines, returning Thu, 11 Sep, priced at £311 just found
American Airlines
Mon, 8 Sep - Thu, 11 Sep
DTW
Detroit
DSM
Des Moines
£341 Return, just found
£341
Return
just found
Select American Airlines flight, departing Mon, 8 Sep from Detroit to Des Moines, returning Thu, 11 Sep, priced at £341 just found
American Airlines
Mon, 8 Sep - Thu, 11 Sep
DTW
Detroit
DSM
Des Moines
£349 Return, just found
£349
Return
just found
Select American Airlines flight, departing Mon, 8 Sep from Detroit to Des Moines, returning Thu, 11 Sep, priced at £349 just found
Delta
Mon, 8 Sep - Thu, 11 Sep
DTW
Detroit
DSM
Des Moines
£360 Return, just found
£360
Return
just found
Select Delta flight, departing Mon, 8 Sep from Detroit to Des Moines, returning Thu, 11 Sep, priced at £360 just found
Delta
Mon, 8 Sep - Thu, 11 Sep
DTW
Detroit
DSM
Des Moines
£361 Return, just found
£361
Return
just found
Select Delta flight, departing Mon, 8 Sep from Detroit to Des Moines, returning Thu, 11 Sep, priced at £361 just found
United
Mon, 8 Sep - Thu, 11 Sep
DTW
Detroit
DSM
Des Moines
£367 Return, just found
£367
Return
just found
Select United flight, departing Mon, 8 Sep from Detroit to Des Moines, returning Thu, 11 Sep, priced at £367 just found
Delta
Mon, 8 Sep - Thu, 11 Sep
DTW
Detroit
DSM
Des Moines
£368 Return, just found
£368
Return
just found
Select Delta flight, departing Mon, 8 Sep from Detroit to Des Moines, returning Thu, 11 Sep, priced at £368 just found
American Airlines
Mon, 8 Sep - Thu, 11 Sep
DTW
Detroit
DSM
Des Moines
£371 Return, just found
£371
Return
just found
Select American Airlines flight, departing Mon, 8 Sep from Detroit to Des Moines, returning Thu, 11 Sep, priced at £371 just found
Delta
Mon, 8 Sep - Thu, 11 Sep
DTW
Detroit
DSM
Des Moines
£376 Return, just found
£376
Return
just found
Select Delta flight, departing Mon, 8 Sep from Detroit to Des Moines, returning Thu, 11 Sep, priced at £376 just found
Delta
Mon, 8 Sep - Thu, 11 Sep
DTW
Detroit
DSM
Des Moines
£378 Return, just found
£378
Return
just found
Select Delta flight, departing Mon, 8 Sep from Detroit to Des Moines, returning Thu, 11 Sep, priced at £378 just found

Find the cheapest month to fly from Detroit (DTW) to Des Moines (DSM)

March is typically the cheapest month to fly

From £123 - £527 per traveller.

Graph displaying average flight prices per month

0
Flight from Detroit to Des Moines route information
Origin airport
Detroit Metropolitan Wayne County
Destination airport
Des Moines Intl.
Return price
£310
Distance
850 km

Compare flights from Detroit to Des Moines easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Detroit to Des Moines. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Des Moines Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Detroit Metropolitan Wayne County to Des Moines Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Detroit Metropolitan Wayne County (DTW) to Des Moines Intl. (DSM)

The easiest way to view the best deals on flights from Detroit to Des Moines today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Detroit Metropolitan Wayne County to Des Moines Intl. start at just £311 and range up to £378.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Detroit and Des Moines
  • booking your flight during September, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Detroit to Des Moines flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Detroit Metropolitan Wayne County to Des Moines Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Frequently asked questions

How much is a flight from Detroit Metropolitan Wayne County Airport (DTW) to DSM?
Within the past 7 days on Expedia, for flights departing within the next year, the lowest price available for a round-trip flight from Metro Airport to Des Moines Intl. Airport (DSM) was £311. Fares this cheap don't wait forever, so make sure you book yours today. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from Metro Airport to Des Moines Intl. Airport (DSM)?
The majority of flights can be conveniently cancelled online, but whether or not you are charged a fee varies between airlines. If you do need to cancel your trip, follow the instructions in the Customer Service Portal.
How do I find cheap flights from Metro Airport to Des Moines Intl. Airport that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Detroit Metropolitan Wayne County Airport (DTW) to Des Moines Intl. Airport flights, you'll see a "no change fees" filter for you to select.
How far is the flight from Detroit Metro Airport to Des Moines Intl. Airport (DSM)?
It's only 860 kilometres between Detroit and Des Moines. Chances are you'll spend more time getting to and from the airport than actually flying!
Which airlines fly direct from Detroit Metropolitan Wayne County Airport (DTW) to Des Moines Intl. Airport (DSM)?
Delta Air Lines (DL) will take you from Detroit Metropolitan Wayne County Airport (DTW) to DSM comfortably and reliably. You can choose from 69 flights each month on this route.
Are DTW to DSM flight tickets cheaper when they're purchased at the last minute?
It is possible to find great last-minute deals from Detroit Metro Airport to DSM, but it's also possible to miss out entirely! As many airlines advertise prices up to a year in advance, it's worth keeping an eye on fares early and being ready to pounce when you see a good bargain. Expedia compares carrier prices and updates flight deals often, so you can feel confident knowing you're always seeing the latest offers.

Explore a world of travel with Expedia

*Available to Expedia members.