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Our top choices for Saint Charles hotels

1. Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport
2.0 star property
Greater South Side
8.6 out of 10, Excellent, (1,824 reviews)
"Very comfortable room in a great area near the airport."
United States
Scott
The price is £60
includes taxes & fees
21 Jun - 22 Jun
Days Inn & Suites by Wyndham Des Moines Airport

2. Fairfield Inn and Suites by Marriott Des Moines West

Fairfield Inn and Suites by Marriott Des Moines West
3.0 star property
West Des Moines
9.2 out of 10, Wonderful, (1,020 reviews)
"The rooms were very nice and clean. The staff were great and breakfast was very good."
United States
Kimberle
The price is £79
includes taxes & fees
21 Jun - 22 Jun
Fairfield Inn and Suites by Marriott Des Moines West

3. AmericInn by Wyndham Osceola

AmericInn by Wyndham Osceola
3.0 star property
Osceola
8.8 out of 10, Excellent, (643 reviews)
"Nice place to stay the kids loved the pool"
United States
joe
The price is £105
includes taxes & fees
5 Jul - 6 Jul
AmericInn by Wyndham Osceola

4. Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport
2.5 star property
Greater South Side
8.8 out of 10, Excellent, (1,009 reviews)
"Great staff friendly and breakfast was great"
United States
Gerald
The price is £99
includes taxes & fees
28 Jun - 29 Jun
Hampton Inn Des Moines-Airport

5. Holiday Inn Express & Suites West Des Moines - Jordan Creek by IHG

Holiday Inn Express & Suites West Des Moines - Jordan Creek by IHG
2.5 star property
West Des Moines
9.2 out of 10, Wonderful, (1,006 reviews)
"great stay."
United States
kenneth
The price is £104
includes taxes & fees
21 Jun - 22 Jun
Holiday Inn Express & Suites West Des Moines - Jordan Creek by IHG

6. Baymont by Wyndham Des Moines Airport

Baymont by Wyndham Des Moines Airport
2.5 star property
Southwestern Hills
9.4 out of 10, Exceptional, (1,180 reviews)
"Clean room, great staff, and wonderful breakfast."
United States
Michael
The price is £77
includes taxes & fees
21 Jun - 22 Jun
Baymont by Wyndham Des Moines Airport

7. Super 8 by Wyndham Osceola IA

Super 8 by Wyndham Osceola IA
2.0 star property
Osceola
8.6 out of 10, Excellent, (282 reviews)
"Easy check in, friendly staff. Very clean. I stay here every year. Has always been great."
United States
Eric
The price is £71
includes taxes & fees
21 Jun - 22 Jun
Super 8 by Wyndham Osceola IA

8. Lakeside Hotel Casino, a Travelodge by Wyndham

Lakeside Hotel Casino, a Travelodge by Wyndham
3.0 star property
Osceola
8.2 out of 10, Very good, (1,026 reviews)
"Great value, nice rooms"
United States
Jan
The price is £70
includes taxes & fees
21 Jun - 22 Jun
Lakeside Hotel Casino, a Travelodge by Wyndham

9. Evergreen Inn

Evergreen Inn
2.5 star property
Osceola
9.0 out of 10, Wonderful, (723 reviews)
"It was a great stay! We loved the place!"
United States
Md Masudur
The price is £43
includes taxes & fees
17 Jun - 18 Jun
Evergreen Inn

10. Drury Inn & Suites West Des Moines

Drury Inn & Suites West Des Moines
3.0 star property
West Des Moines
9.4 out of 10, Exceptional, (1,065 reviews)
"Clean room, great amenities and staff. Enjoyed our stay."
United States
Ryan
The price is £83
includes taxes & fees
21 Jun - 22 Jun
Drury Inn & Suites West Des Moines

11. Homewood Suites by Hilton Des Moines Airport

Homewood Suites by Hilton Des Moines Airport
3.0 star property
Des Moines
9.4 out of 10, Exceptional, (651 reviews)
"The room was nice and spacious"
United States
Linda
The price is £110
includes taxes & fees
28 Jun - 29 Jun
Homewood Suites by Hilton Des Moines Airport

12. Quality Inn & Suites Des Moines Airport

Quality Inn & Suites Des Moines Airport
2.5 star property
Greater South Side
7.6 out of 10, Good, (1,009 reviews)
"Room was clean, staff was very friendly, breakfast was good"
United States
Sonia
The price is £53
includes taxes & fees
29 Jun - 30 Jun
Quality Inn & Suites Des Moines Airport

13. Hyatt Place West Des Moines Jordan Creek

Hyatt Place West Des Moines Jordan Creek
3.0 star property
West Des Moines
9.2 out of 10, Wonderful, (1,011 reviews)
"Clean rooms great breakfast and coffee."
United States
Cynthia
The price is £90
includes taxes & fees
21 Jun - 22 Jun
Hyatt Place West Des Moines Jordan Creek

14. Sleep Inn & Suites West Des Moines near Jordan Creek

Sleep Inn & Suites West Des Moines near Jordan Creek
2.5 star property
West Des Moines
8.8 out of 10, Excellent, (1,009 reviews)
"A wonderful place to stay, friendly and helpful staff. Clean and large rooms, and a great breakfast."
United States
Robin
The price is £73
includes taxes & fees
13 Jul - 14 Jul
Sleep Inn & Suites West Des Moines near Jordan Creek

15. Covered Bridge Inn

Covered Bridge Inn
2.5 star property
Winterset
9.0 out of 10, Wonderful, (795 reviews)
"Recently renovated room with a very helpful staff."
United States
Scott
The price is £85
includes taxes & fees
17 Jun - 18 Jun
Covered Bridge Inn

16. Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University
3.0 star property
Drake
9.4 out of 10, Exceptional, (1,035 reviews)
"Excellent accommodation i always stay here when in town!"
United States
Barbara
The price is £88
includes taxes & fees
5 Jul - 6 Jul
Home2 Suites by Hilton Des Moines at Drake University

17. SpringHill Suites Des Moines West

SpringHill Suites Des Moines West
3.0 star property
West Des Moines
8.6 out of 10, Excellent, (1,021 reviews)
"Clean, comfortable room and an enjoyable breakfast."
United States
Jim
The price is £101
includes taxes & fees
21 Jun - 22 Jun
SpringHill Suites Des Moines West

18. Fairfield Inn & Suites by Marriott Des Moines Airport

Fairfield Inn & Suites by Marriott Des Moines Airport
3.0 star property
Des Moines
9.2 out of 10, Wonderful, (662 reviews)
"Friendly staff. Good breakfast."
United States
Allen
The price is £108
includes taxes & fees
21 Jun - 22 Jun
Fairfield Inn & Suites by Marriott Des Moines Airport

19. Wildwood Lodge

Wildwood Lodge
3.0 star property
Clive
9.6 out of 10, Exceptional, (1,270 reviews)
"Perfect place to stay!"
United States
Dave
The price is £92
includes taxes & fees
24 Jun - 25 Jun
Wildwood Lodge

20. Cobblestone Inn & Suites - Winterset, IA

Cobblestone Inn & Suites - Winterset, IA
2.5 star property
Winterset
9.2 out of 10, Wonderful, (752 reviews)
"Room was very clean and staff was friendly!"
United States
Cheryl
The price is £104
includes taxes & fees
1 Jul - 2 Jul
Cobblestone Inn & Suites - Winterset, IA
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What is the best area to stay in Saint Charles?
The best area to stay in Saint Charles is the historic Main Street district, particularly for those who appreciate convenience and local charm.

This area is the heart of Saint Charles, known for its well-preserved 19th-century buildings and a pedestrian-friendly layout. Main Street itself is lined with independent shops, local eateries, and a few small museums. It's easy to walk from one end to the other, enjoying the architecture and the river views.

Couples will find this area particularly appealing for a relaxing getaway. You can enjoy a leisurely stroll along the Katy Trail, which runs adjacent to Main Street and offers scenic views of the Missouri River. Evenings can be spent dining at one of the upscale restaurants or enjoying a glass of local wine at a nearby establishment.

For solo travellers, staying on or near Main Street provides easy access to everything without needing to rely on a car. You can explore the historic sites, browse the boutiques, and easily find a spot for a coffee or a meal.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Saint Charles.
How can I save on a Saint Charles hotel booking with Expedia?
Members always get our best prices. Find our best Saint Charles hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.
How much is the nightly rate at a Saint Charles hotel?
Prices for hotels in Saint Charles often vary, but you can find a great deal from £45 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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