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Our top choices for Saint Charles hotels

Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport
2.0 star property
Greater South Side
8.6 out of 10, Excellent, (1,773 reviews)
"Clean comfy room, nice staff and goi breakfast "
United States
Errin
The price is £62
includes taxes & fees
17 May - 18 May
Days Inn & Suites by Wyndham Des Moines Airport

Baymont by Wyndham Des Moines Airport

Baymont by Wyndham Des Moines Airport
2.5 star property
Southwestern Hills
9.4 out of 10, Exceptional, (1,158 reviews)
"We travel a good deal, and without question, this the nicest Baymont weve ever stayed at."
United States
William
The price is £73
includes taxes & fees
3 May - 4 May
Baymont by Wyndham Des Moines Airport

Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport
2.5 star property
Greater South Side
8.8 out of 10, Excellent, (1,000 reviews)
"Breakfast was excellent and staff were the best! "
United States
SUMMER
The price is £101
includes taxes & fees
24 May - 25 May
Hampton Inn Des Moines-Airport

AmericInn by Wyndham Des Moines Airport

AmericInn by Wyndham Des Moines Airport
3.0 star property
Greater South Side
8.0 out of 10, Very good, (1,000 reviews)
"Clean room, staff was friendly, easy to find and park"
United States
Heidi
The price is £57
includes taxes & fees
3 May - 4 May
AmericInn by Wyndham Des Moines Airport

Quality Inn & Suites Des Moines Airport

Quality Inn & Suites Des Moines Airport
2.5 star property
Greater South Side
7.4 out of 10, Good, (1,005 reviews)
"Stayed here for my flight the next morning and everything went smoothly the front desk was very helpful and everything was clean"
United States
Kimberly
The price is £57
includes taxes & fees
25 May - 26 May
Quality Inn & Suites Des Moines Airport

Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University
3.0 star property
Drake
9.4 out of 10, Exceptional, (1,003 reviews)
"Overall great stay , staff was very accommodating! "
United States
Karen
The price is £80
includes taxes & fees
10 May - 11 May
Home2 Suites by Hilton Des Moines at Drake University

Holiday Inn Express & Suites West Des Moines - Jordan Creek by IHG

Holiday Inn Express & Suites West Des Moines - Jordan Creek by IHG
2.5 star property
West Des Moines
9.2 out of 10, Wonderful, (1,000 reviews)
"Nice place"
United States
Scott
The price is £87
includes taxes & fees
5 May - 6 May
Holiday Inn Express & Suites West Des Moines - Jordan Creek by IHG

Homewood Suites by Hilton Des Moines Airport

Homewood Suites by Hilton Des Moines Airport
3.0 star property
Des Moines
9.4 out of 10, Exceptional, (637 reviews)
"The property was very clean, the staff was friendly, the pool was nice, they also have an outdoor basketball court which was nice. "
United States
Brittany
The price is £101
includes taxes & fees
17 May - 18 May
Homewood Suites by Hilton Des Moines Airport

Lakeside Hotel Casino, a Travelodge by Wyndham

Lakeside Hotel Casino, a Travelodge by Wyndham
3.0 star property
Osceola
8.2 out of 10, Very good, (1,003 reviews)
"We enjoyed our time there"
United States
Robert
The price is £69
includes taxes & fees
20 May - 21 May
Lakeside Hotel Casino, a Travelodge by Wyndham

Quality Inn West Des Moines - Clive

Quality Inn West Des Moines - Clive
2.0 star property
West Des Moines
7.0 out of 10, Good, (57 reviews)
"Staff was so nice. Room was really clean and comfortable. Will stay again if in the area. "
United States
Chris
The price is £50
includes taxes & fees
7 May - 8 May
Quality Inn West Des Moines - Clive

Hyatt Place West Des Moines Jordan Creek

Hyatt Place West Des Moines Jordan Creek
3.0 star property
West Des Moines
9.2 out of 10, Wonderful, (1,003 reviews)
"Very nice facility. Room was large and comfortable. Breakfast was excellent."
United States
Kevin
The price is £81
includes taxes & fees
10 May - 11 May
Hyatt Place West Des Moines Jordan Creek

Country Inn & Suites by Radisson, Des Moines West, IA

Country Inn & Suites by Radisson, Des Moines West, IA
3.0 star property
Clive
8.8 out of 10, Excellent, (1,000 reviews)
"Clean, nice breakfast, friendly staff. "
United States
Scott
The price is £72
includes taxes & fees
24 May - 25 May
Country Inn & Suites by Radisson, Des Moines West, IA

Clarion Inn Des Moines Airport

Clarion Inn Des Moines Airport
3.0 star property
Watrous South
7.0 out of 10, Good, (183 reviews)
"Perfect stay"
United States
Maria
The price is £43
includes taxes & fees
31 May - 1 Jun
Clarion Inn Des Moines Airport

Fairfield Inn and Suites by Marriott Des Moines West

Fairfield Inn and Suites by Marriott Des Moines West
3.0 star property
West Des Moines
9.2 out of 10, Wonderful, (1,000 reviews)
The price is £82
includes taxes & fees
3 May - 4 May
Fairfield Inn and Suites by Marriott Des Moines West

Tru By Hilton Norwalk Des Moines

Tru By Hilton Norwalk Des Moines
2.5 star property
Norwalk
9.4 out of 10, Exceptional, (39 reviews)
"Awesome place. Room was clean quiet and bed was comfortable."
United States
Michael
The price is £64
includes taxes & fees
10 May - 11 May
Tru By Hilton Norwalk Des Moines

SpringHill Suites Des Moines West

SpringHill Suites Des Moines West
3.0 star property
West Des Moines
8.6 out of 10, Excellent, (1,000 reviews)
"It is very nice place to.. clean and very nice Staff"
United States
Mary
The price is £81
includes taxes & fees
10 May - 11 May
SpringHill Suites Des Moines West

Holiday Inn Express & Suites Des Moines Downtown by IHG

Holiday Inn Express & Suites Des Moines Downtown by IHG
2.5 star property
Downtown Des Moines
9.2 out of 10, Wonderful, (1,000 reviews)
"We especially enjoyed the hot hot tub and the truly friendly staff. Breakfast was great too. Everything was clean."
United States
Carol
The price is £97
includes taxes & fees
3 May - 4 May
Holiday Inn Express & Suites Des Moines Downtown by IHG

Woodspring Suites West Des Moines

Woodspring Suites West Des Moines
2.5 star property
West Des Moines
7.6 out of 10, Good, (258 reviews)
"Nice place to stay. Definitely designed for long term guests. I would stay here again thoigh"
United States
Larry
The price is £49
includes taxes & fees
8 May - 9 May
Woodspring Suites West Des Moines

TownePlace Suites by Marriott Des Moines West/Jordan Creek

TownePlace Suites by Marriott Des Moines West/Jordan Creek
3.0 star property
West Des Moines
8.8 out of 10, Excellent, (870 reviews)
"Breakfast and comfortable room"
United States
Michael
The price is £81
includes taxes & fees
5 May - 6 May
TownePlace Suites by Marriott Des Moines West/Jordan Creek

Drury Inn & Suites West Des Moines

Drury Inn & Suites West Des Moines
3.0 star property
West Des Moines
9.4 out of 10, Exceptional, (1,020 reviews)
"Love this hotel"
United States
Morgan
The price is £82
includes taxes & fees
25 May - 26 May
Drury Inn & Suites West Des Moines
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Saint Charles attractions

Learn more about Saint Charles

Venture to sights like Imes Bridge as you discover the local area in Saint Charles.

cuttler-donahoe covered bridge, iowa

Top Saint Charles Hotel Reviews

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Frequently asked questions

What is the best area to stay in Saint Charles?
The best area to stay in Saint Charles is the historic Main Street district, particularly for those who appreciate convenience and local charm.

This area is the heart of Saint Charles, known for its well-preserved 19th-century buildings and a pedestrian-friendly layout. Main Street itself is lined with independent shops, local eateries, and a few small museums. It's easy to walk from one end to the other, enjoying the architecture and the river views.

Couples will find this area particularly appealing for a relaxing getaway. You can enjoy a leisurely stroll along the Katy Trail, which runs adjacent to Main Street and offers scenic views of the Missouri River. Evenings can be spent dining at one of the upscale restaurants or enjoying a glass of local wine at a nearby establishment.

For solo travellers, staying on or near Main Street provides easy access to everything without needing to rely on a car. You can explore the historic sites, browse the boutiques, and easily find a spot for a coffee or a meal.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Saint Charles.
How can I save on a Saint Charles hotel booking with Expedia?
Members always get our best prices. Find our best Saint Charles hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.
How much is the nightly rate at a Saint Charles hotel?
Prices for hotels in Saint Charles often vary, but you can find a great deal from £44 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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