£86 Cheap Flights from Santo Domingo (SDQ) to Medellín (MDE)

View £86 flight on Tue, 26 May 2026Opens in a new window

Flight 1

Popular airlines from Las Americas Intl. Airport (SDQ) to Jose Maria Cordova Intl. Airport (MDE)

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Cheap Flights from Santo Domingo (SDQ) to Medellín (MDE)

Prices were available within the past 7 days and start at £86 for one-way flights and £182 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Arajet
Tue, 26 May - Tue, 2 Jun
SDQ
Santo Domingo
MDE
Medellín
£182 Return, found 1 day ago
£182
Return
found 1 day ago
Select Arajet flight, departing Tue, 26 May from Santo Domingo to Medellín, returning Tue, 2 Jun, priced at £182 found 1 day ago
Arajet
Sun, 10 May - Thu, 14 May
SDQ
Santo Domingo
MDE
Medellín
£185 Return, found 2 days ago
£185
Return
found 2 days ago
Select Arajet flight, departing Sun, 10 May from Santo Domingo to Medellín, returning Thu, 14 May, priced at £185 found 2 days ago
Arajet
Thu, 5 Nov - Fri, 13 Nov
SDQ
Santo Domingo
MDE
Medellín
£199 Return, found 6 days ago
£199
Return
found 6 days ago
Select Arajet flight, departing Thu, 5 Nov from Santo Domingo to Medellín, returning Fri, 13 Nov, priced at £199 found 6 days ago
Arajet
Thu, 3 Dec - Thu, 10 Dec
SDQ
Santo Domingo
MDE
Medellín
£201 Return, found 1 day ago
£201
Return
found 1 day ago
Select Arajet flight, departing Thu, 3 Dec from Santo Domingo to Medellín, returning Thu, 10 Dec, priced at £201 found 1 day ago
Arajet
Tue, 4 Aug - Thu, 6 Aug
SDQ
Santo Domingo
MDE
Medellín
£204 Return, found 5 days ago
£204
Return
found 5 days ago
Select Arajet flight, departing Tue, 4 Aug from Santo Domingo to Medellín, returning Thu, 6 Aug, priced at £204 found 5 days ago
Arajet
Sun, 4 Oct - Sun, 1 Nov
SDQ
Santo Domingo
MDE
Medellín
£204 Return, found 6 hours ago
£204
Return
found 6 hours ago
Select Arajet flight, departing Sun, 4 Oct from Santo Domingo to Medellín, returning Sun, 1 Nov, priced at £204 found 6 hours ago
Arajet
Tue, 5 May - Thu, 7 May
SDQ
Santo Domingo
MDE
Medellín
£206 Return, found 1 day ago
£206
Return
found 1 day ago
Select Arajet flight, departing Tue, 5 May from Santo Domingo to Medellín, returning Thu, 7 May, priced at £206 found 1 day ago
avianca
Fri, 15 May - Sun, 17 May
SDQ
Santo Domingo
MDE
Medellín
£263 Return, found 3 days ago
£263
Return
found 3 days ago
Select avianca flight, departing Fri, 15 May from Santo Domingo to Medellín, returning Sun, 17 May, priced at £263 found 3 days ago
Copa
Fri, 22 May - Tue, 26 May
SDQ
Santo Domingo
MDE
Medellín
£267 Return, found 14 hours ago
£267
Return
found 14 hours ago
Select Copa flight, departing Fri, 22 May from Santo Domingo to Medellín, returning Tue, 26 May, priced at £267 found 14 hours ago
American Airlines
Sun, 6 Dec - Thu, 24 Dec
SDQ
Santo Domingo
MDE
Medellín
£873 Return, found 6 hours ago
£873
Return
found 6 hours ago
Select American Airlines flight, departing Sun, 6 Dec from Santo Domingo to Medellín, returning Thu, 24 Dec, priced at £873 found 6 hours ago

Alternative airports near Medellín

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Jose Maria Cordova Intl. MDE. Cheapest option available. Average driving time to city centre is 29 minutes. Flights from £263
MDE
Jose Maria Cordova Intl.
Cheapest
Average driving time to city centre29 min
Flights from £263

Find the cheapest month to fly from Santo Domingo (SDQ) to Medellín (MDE)

May is typically the cheapest month to fly

From £155 - £241 per traveller.

Frequently asked questions

How much does a flight from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.) cost?
One-way flights typically cost between £287 and £1,428 and return flights often range between £636 and £1,866. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Anaa (AAA) to Toronto, ON (YYZ-Pearson Intl.) ticket fares go up or down.
What is the cheapest month to fly from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.)?
August is typically the cheapest month to fly from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.), with average return fares of approximately £445. This is about 18% lower than the average price throughout the year. August often sees lower prices as it's generally a shoulder season for travel, with fewer holiday crowds. Other cheap months to fly from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.) include July and September.
Which airlines fly direct from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.)?
Enter SDQ to MDE and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.)?
To find a cheap flight from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.)?
The best airline to fly with from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.) will differ from traveller to traveller. If you like to fly early, DM offers early morning flights. If price is the most important factor, DM typically offers the lowest fares. AV offers the most daily flights from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.), which is brilliant if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.)?
When looking for the best time to fly from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.), it's a balance between price and popularity. Based on booking data from the past year, you'll find the cheapest flights in August and July, with average prices around £445 for a return trip. However, the most popular months for this route are October and March, which means you'll have plenty of flight options and flexibility in your schedule, though prices might be a bit higher. Consider if saving money or having more choice is your priority for your trip to Medellín.
How many flights per day from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.)?
There is approximately 1 nonstop flight per day from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.). For even more choice, look at flights that include layovers, as there are around 16 connecting flights per day. Some common connection points include El Dorado Intl. (BOG), Tocumen Intl. (PTY), and Miami Intl. (MIA).
What is the earliest flight from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.)?
The earliest flight from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.) typically departs at approximately 1:05 AM local time, operated by B6. This is a seasonal service active in July and August. An early departure like this can help maximise your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.)?
You'll typically find the most flights from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.) on a Thursday, with around 14 flights available. This gives you a good selection of options for your travel plans. Major airlines on this route include American Airlines, Copa Airlines, and Avianca.
What are the most popular departure times for flights from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.)?
The most popular departure times for flights from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.) are between 12pm and 3pm. This accounts for around 34% of total traffic. Many major carriers, including Avianca, Copa Airlines and American Airlines, offer flights during this window. This timing works well for many travelers as it allows for a morning in Santo Domingo and an afternoon arrival in Medellín.
How long does it take to fly from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.)?
Flying nonstop from SDQ to MDE takes around 2 hours 30 minutes, with the route covering approximately 932 miles. Flights with a layover typically take 18 hours longer than direct options. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.)?
Select the "Business class" and "First class" filters when looking for SDQ to MDE flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.) flight with Expedia?
It's easy to earn miles on a Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Medellin from Las Americas Intl. (SDQ)?
From Las Americas Intl. (SDQ), you can fly directly into Jose Maria Cordova Intl. (MDE) to reach Medellin. Some flights may connect through major hubs like El Dorado Intl. (BOG), Liberty Intl. (EWR), John F. Kennedy Intl. (JFK) before reaching Medellin. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.) at the last minute?
Typically, booking a last minute flight from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.) flight and hotel package?
Securing a Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.)?
If you booked your Santo Domingo (SDQ-Las Americas Intl.) to Medellín (MDE-José María Córdova Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Las Americas Intl.
Destination airport
José María Córdova Intl.
Airlines serving
American Airlines, Arajet, Copa, avianca
Return price
£181
Distance
1490 km
Average flight time
1 hour 33 mins

Book with confidence

Compare flights from Santo Domingo to Medellín easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Santo Domingo to Medellín. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to José María Córdova Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Las Americas Intl. to José María Córdova Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Las Americas Intl. (SDQ) to José María Córdova Intl. (MDE)

The easiest way to view the best deals on flights from Santo Domingo to Medellín today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Las Americas Intl. to José María Córdova Intl. start at just £182 and range up to £873.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Santo Domingo and Medellín
  • booking your flight during May, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Santo Domingo to Medellín flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Las Americas Intl. to José María Córdova Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Santo Domingo to Medellín easily and book with confidence

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