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£136 Cheap Flights from Santiago (SCL) to Medellín (MDE)

View £136 flight on Wed, 14 Oct 2026Opens in a new window

Popular airlines from Santiago Intl. Airport (SCL) to Jose Maria Cordova Intl. Airport (MDE)

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Cheap Flights from Santiago (SCL) to Medellín (MDE)

Prices were available within the past 7 days and start at £136 for one-way flights and £281 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Wed, 14 Oct - Wed, 21 Oct
SCL
Santiago
MDE
Medellín
£281 Return, found 1 day ago
£281
Return
found 1 day ago
Select LATAM Airlines Group flight, departing Wed, 14 Oct from Santiago to Medellín, returning Wed, 21 Oct, priced at £281 found 1 day ago
LATAM Airlines Group
Wed, 14 Oct - Wed, 21 Oct
SCL
Santiago
MDE
Medellín
£296 Return, found 1 day ago
£296
Return
found 1 day ago
Select LATAM Airlines Group flight, departing Wed, 14 Oct from Santiago to Medellín, returning Wed, 21 Oct, priced at £296 found 1 day ago
LATAM Airlines Group
Fri, 21 Aug - Tue, 25 Aug
SCL
Santiago
MDE
Medellín
£311 Return, found 1 day ago
£311
Return
found 1 day ago
Select LATAM Airlines Group flight, departing Fri, 21 Aug from Santiago to Medellín, returning Tue, 25 Aug, priced at £311 found 1 day ago
LATAM Airlines Group
Fri, 21 Aug - Tue, 25 Aug
SCL
Santiago
MDE
Medellín
£315 Return, found 1 day ago
£315
Return
found 1 day ago
Select LATAM Airlines Group flight, departing Fri, 21 Aug from Santiago to Medellín, returning Tue, 25 Aug, priced at £315 found 1 day ago
LATAM Airlines Group
Fri, 21 Aug - Tue, 25 Aug
SCL
Santiago
MDE
Medellín
£316 Return, found 1 day ago
£316
Return
found 1 day ago
Select LATAM Airlines Group flight, departing Fri, 21 Aug from Santiago to Medellín, returning Tue, 25 Aug, priced at £316 found 1 day ago
LATAM Airlines Group
Fri, 21 Aug - Tue, 25 Aug
SCL
Santiago
MDE
Medellín
£320 Return, found 1 day ago
£320
Return
found 1 day ago
Select LATAM Airlines Group flight, departing Fri, 21 Aug from Santiago to Medellín, returning Tue, 25 Aug, priced at £320 found 1 day ago
LATAM Airlines Group
Fri, 21 Aug - Tue, 25 Aug
SCL
Santiago
MDE
Medellín
£326 Return, found 1 day ago
£326
Return
found 1 day ago
Select LATAM Airlines Group flight, departing Fri, 21 Aug from Santiago to Medellín, returning Tue, 25 Aug, priced at £326 found 1 day ago
LATAM Airlines Group
Fri, 21 Aug - Tue, 25 Aug
SCL
Santiago
MDE
Medellín
£326 Return, found 1 day ago
£326
Return
found 1 day ago
Select LATAM Airlines Group flight, departing Fri, 21 Aug from Santiago to Medellín, returning Tue, 25 Aug, priced at £326 found 1 day ago
Copa
Fri, 21 Aug - Tue, 25 Aug
SCL
Santiago
MDE
Medellín
£362 Return, found 1 day ago
£362
Return
found 1 day ago
Select Copa flight, departing Fri, 21 Aug from Santiago to Medellín, returning Tue, 25 Aug, priced at £362 found 1 day ago
avianca
Fri, 21 Aug - Tue, 25 Aug
SCL
Santiago
MDE
Medellín
£369 Return, found 1 day ago
£369
Return
found 1 day ago
Select avianca flight, departing Fri, 21 Aug from Santiago to Medellín, returning Tue, 25 Aug, priced at £369 found 1 day ago

Frequently asked questions

How much does a flight from Santiago (SCL-Arturo Merino Benitez) to Medellín (MDE-José María Córdova Intl.) cost?
You can find one-way and return flights from SCL to MDE with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when SCL to MDE ticket fares go up or down.
What is the cheapest month to fly from Santiago (SCL-Arturo Merino Benitez) to Medellín (MDE-José María Córdova Intl.)?
The cheapest months to fly from SCL to MDE are typically during off-peak season when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you are able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Santiago (SCL-Arturo Merino Benitez) to Medellín (MDE-José María Córdova Intl.)?
Only one airline offers direct flights from Santiago (SCL-Arturo Merino Benitez) to Medellín (MDE-José María Córdova Intl.). JetSmart operates 7 direct flights from Santiago (SCL-Arturo Merino Benitez) to Medellín (MDE-José María Córdova Intl.) every week.
What is the cheapest airline that flies from Santiago (SCL-Arturo Merino Benitez) to Medellín (MDE-José María Córdova Intl.)?
JetSmart is one of the cheapest airlines offering nonstop return flights from Santiago (SCL-Arturo Merino Benitez) to Medellín (MDE-José María Córdova Intl.), with tickets starting from around £246 for flights that can be booked for departure within the next year. JetSmart also offers one of the cheapest connecting return flights on this route, with prices starting from around £456. These prices are per adult for economy/coach class. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
How do I find cheap flights from Santiago (SCL) to Medellín (MDE)?
To find a cheap flight from Santiago (SCL)Medellín (MDE), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Santiago (SCL-Arturo Merino Benitez) to Medellín (MDE-José María Córdova Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Santiago (SCL-Arturo Merino Benitez) to Medellín (MDE-José María Córdova Intl.)?
The earliest flight from Santiago (SCL-Arturo Merino Benitez) to Medellín (MDE-José María Córdova Intl.) typically departs around 12:00 AM local time, operated by Copa. This is a seasonal service active in May and June. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
How long does it take to fly from Santiago (SCL-Arturo Merino Benitez) to Medellín (MDE-José María Córdova Intl.)?
A non-stop flight from Santiago (SCL-Arturo Merino Benitez) to Medellín (MDE-José María Córdova Intl.) typically takes around 6 hours 30 minutes. This route covers a distance of approximately 4,427 kilometers. If you opt for a one-stop flight, your journey will usually be longer, taking about 9 hours 30 minutes. Flights with two or more stops generally take around 18 hours. Keep in mind that actual flight times can vary due to factors like wind patterns and air traffic, so it's always a good idea to allow for some extra time when planning your trip.
Can you fly business or first class from Santiago (SCL) to Medellín (MDE)?
Select the "Business class" and "First class" filters when looking for Santiago (SCL) to Medellín (MDE) flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Santiago (SCL-Arturo Merino Benitez) to Medellín (MDE-José María Córdova Intl.) flight with Expedia?
It's easy to earn miles on a Santiago (SCL-Arturo Merino Benitez) to Medellín (MDE-José María Córdova Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Medellín (MDE) from Santiago (SCL)?
If you're planning to travel to Medellin from Arturo Merino Benitez (SCL), you can fly directly into Jose Maria Cordova Intl. (MDE). Some flights may connect through major hubs like Jorge Chavez Intl. (LIM), Guarulhos - Governor Andre Franco Montoro Intl. (GRU), or El Dorado Intl. (BOG) before reaching Medellin. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Santiago (SCL-Arturo Merino Benitez) to Medellín (MDE-José María Córdova Intl.) at the last minute?
Typically, booking a last minute flight from Santiago (SCL-Arturo Merino Benitez) to Medellín (MDE-José María Córdova Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Santiago (SCL-Arturo Merino Benitez) to Medellín (MDE-José María Córdova Intl.) flight and hotel package?
Securing a Santiago (SCL-Arturo Merino Benitez) to Medellín (MDE-José María Córdova Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Santiago (SCL) to Medellín (MDE)?
If you booked your Santiago (SCL)Medellín (MDE) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Arturo Merino Benitez
Destination airport
José María Córdova Intl.
Airlines serving
Copa, LATAM Airlines Group, avianca
Return price
£280
Distance
4400 km
Average flight time
7 hours 24 mins

Book with confidence

Compare flights from Santiago to Medellín easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Santiago to Medellín. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to José María Córdova Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Arturo Merino Benitez to José María Córdova Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Arturo Merino Benitez (SCL) to José María Córdova Intl. (MDE)

The easiest way to view the best deals on flights from Santiago to Medellín today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Arturo Merino Benitez to José María Córdova Intl. start at just £281 and range up to £369.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Santiago and Medellín
  • booking your flight during October, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Santiago to Medellín flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Arturo Merino Benitez to José María Córdova Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Santiago to Medellín easily and book with confidence

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*Available to Expedia members.