£179 Cheap Flights from San Francisco (SFO) to Medellín (MDE)

View £179 flight on Tue, 14 Jul 2026Opens in a new window

Popular airlines from San Francisco International Airport (SFO) to Jose Maria Cordova Intl. Airport (MDE)

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Cheap Flights from San Francisco (SFO) to Medellín (MDE)

Prices were available within the past 7 days and start at £179 for one-way flights and £478 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Thu, 14 May - Thu, 21 May
SFO
San Francisco
MDE
Medellín
£478 Return, just found
£478
Return
just found
Select Copa flight, departing Thu, 14 May from San Francisco to Medellín, returning Thu, 21 May, priced at £478 just found
Copa
Thu, 14 May - Thu, 21 May
SFO
San Francisco
MDE
Medellín
£489 Return, just found
£489
Return
just found
Select Copa flight, departing Thu, 14 May from San Francisco to Medellín, returning Thu, 21 May, priced at £489 just found
Copa
Thu, 14 May - Thu, 21 May
SFO
San Francisco
MDE
Medellín
£500 Return, just found
£500
Return
just found
Select Copa flight, departing Thu, 14 May from San Francisco to Medellín, returning Thu, 21 May, priced at £500 just found
Copa
Sat, 30 May - Sat, 6 Jun
SFO
San Francisco
MDE
Medellín
£502 Return, found 2 days ago
£502
Return
found 2 days ago
Select Copa flight, departing Sat, 30 May from San Francisco to Medellín, returning Sat, 6 Jun, priced at £502 found 2 days ago
Copa
Thu, 14 May - Thu, 21 May
SFO
San Francisco
MDE
Medellín
£511 Return, just found
£511
Return
just found
Select Copa flight, departing Thu, 14 May from San Francisco to Medellín, returning Thu, 21 May, priced at £511 just found
avianca
Thu, 14 May - Thu, 21 May
SFO
San Francisco
MDE
Medellín
£512 Return, just found
£512
Return
just found
Select avianca flight, departing Thu, 14 May from San Francisco to Medellín, returning Thu, 21 May, priced at £512 just found
Copa
Sat, 30 May - Sat, 6 Jun
SFO
San Francisco
MDE
Medellín
£515 Return, found 2 days ago
£515
Return
found 2 days ago
Select Copa flight, departing Sat, 30 May from San Francisco to Medellín, returning Sat, 6 Jun, priced at £515 found 2 days ago
American Airlines
Thu, 14 May - Thu, 21 May
SFO
San Francisco
MDE
Medellín
£516 Return, just found
£516
Return
just found
Select American Airlines flight, departing Thu, 14 May from San Francisco to Medellín, returning Thu, 21 May, priced at £516 just found
LATAM Airlines Group
Sat, 23 May - Sun, 31 May
SFO
San Francisco
MDE
Medellín
£835 Return, found 2 days ago
£835
Return
found 2 days ago
Select LATAM Airlines Group flight, departing Sat, 23 May from San Francisco to Medellín, returning Sun, 31 May, priced at £835 found 2 days ago
Aeromexico
Sun, 31 May - Sun, 7 Jun
SFO
San Francisco
MDE
Medellín
£868 Return, found 2 days ago
£868
Return
found 2 days ago
Select Aeromexico flight, departing Sun, 31 May from San Francisco to Medellín, returning Sun, 7 Jun, priced at £868 found 2 days ago

Find the cheapest month to fly from San Francisco (SFO) to Medellín (MDE)

May is typically the cheapest month to fly

From £289 - £440 per traveller.

Frequently asked questions

What is the cheapest month to fly from San Francisco, CA (SFO-San Francisco Intl.) to Medellín (MDE-José María Córdova Intl.)?
May is typically the cheapest month to fly from San Francisco, CA (SFO-San Francisco Intl.) to Medellín (MDE-José María Córdova Intl.), with average return fares of approximately £406. This is about 13% lower than the average price throughout the year. May often sees lower prices as it's outside of peak holiday seasons, leading to less demand. Other cheap months to fly from San Francisco, CA (SFO-San Francisco Intl.) to Medellín (MDE-José María Córdova Intl.) include August and September.*Averages based on flights available on Expedia in the last year.
How do I find cheap flights from San Francisco, CA (SFO-San Francisco Intl.) to Medellín (MDE-José María Córdova Intl.)?
To find a cheap flight from San Francisco, CA (SFO-San Francisco Intl.) to Medellín (MDE-José María Córdova Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from San Francisco, CA (SFO-San Francisco Intl.) to Medellín (MDE-José María Córdova Intl.)?
The best time to fly from San Francisco International Airport (SFO) to Medellín (MDE) is typically May or September. These months offer a great balance, with average return flight prices around £406. While we don't have specific popularity data for these months, they often fall outside peak holiday seasons, which can mean a more relaxed travel experience. This information is based on booking data from the past year.*Prices based on flights available on Expedia in the last year.
How many flights per day from San Francisco, CA (SFO-San Francisco Intl.) to Medellín (MDE-José María Córdova Intl.)?
There are approximately 89 connecting flights per day from San Francisco International (SFO) to José María Córdova International (MDE). Some common connection points include El Salvador International (SAL), Hartsfield-Jackson Atlanta International (ATL), and Los Angeles International (LAX).
What is the earliest flight from San Francisco, CA (SFO-San Francisco Intl.) to Medellín (MDE-José María Córdova Intl.)?
The earliest flight from San Francisco International Airport (SFO) to Medellín (MDE-José María Córdova Intl.) typically departs at approximately 12:05 AM local time, operated by Avianca. This is a seasonal service active in July, August, September, and October. An early departure like this can help you maximise your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from San Francisco, CA (SFO-San Francisco Intl.) to Medellín (MDE-José María Córdova Intl.)?
You'll typically find the most flights from San Francisco, CA (SFO-San Francisco Intl.) to Medellín (MDE-José María Córdova Intl.) on a Thursday, with around 48 flights available. This gives you plenty of options for your travel plans. Major airlines on this route include United Airlines, American Airlines, and Delta Air Lines. Thursday offers notably more flight options compared to other days of the week.
What are the most popular departure times for flights from San Francisco, CA (SFO-San Francisco Intl.) to Medellín (MDE-José María Córdova Intl.)?
The most popular departure times for flights from San Francisco International Airport (SFO) to José María Córdova International Airport (MDE) are in the early morning, from 12am to 3am. Approximately 32% of passengers prefer this time window. Many major carriers, including Copa, Avianca and United Airlines, offer flights during this window. These times work well if you prefer to travel overnight and arrive at your destination in the morning.
How long does it take to fly from San Francisco, CA (SFO-San Francisco Intl.) to Medellín (MDE-José María Córdova Intl.)?
A flight from SFO to MDE with a layover takes around 18 hours 30 minutes, with the route covering approximately 3,656 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from San Francisco, CA (SFO-San Francisco Intl.) to Medellín (MDE-José María Córdova Intl.)?
Select the "Business class" and "First class" filters when looking for SFO to MDE flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a San Francisco, CA (SFO-San Francisco Intl.) to Medellín (MDE-José María Córdova Intl.) flight with Expedia?
It's easy to earn miles on a San Francisco, CA (SFO-San Francisco Intl.) to Medellín (MDE-José María Córdova Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Medellin from San Francisco Intl. (SFO)?
From San Francisco Intl. (SFO), you can fly into Jose Maria Cordova Intl. (MDE) to reach Medellin. Some flights may connect through major hubs like El Salvador Intl. (SAL), Hartsfield-Jackson Atlanta Intl. (ATL), Los Angeles Intl. (LAX) before reaching Medellin. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from San Francisco, CA (SFO-San Francisco Intl.) to Medellín (MDE-José María Córdova Intl.) at the last minute?
Typically, booking a last minute flight from San Francisco, CA (SFO-San Francisco Intl.) to Medellín (MDE-José María Córdova Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a San Francisco, CA (SFO-San Francisco Intl.) to Medellín (MDE-José María Córdova Intl.) flight and hotel package?
Securing a San Francisco, CA (SFO-San Francisco Intl.) to Medellín (MDE-José María Córdova Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from San Francisco, CA (SFO-San Francisco Intl.) to Medellín (MDE-José María Córdova Intl.)?
If you booked your San Francisco, CA (SFO-San Francisco Intl.) to Medellín (MDE-José María Córdova Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
San Francisco Intl.
Destination airport
José María Córdova Intl.
Return price
£478
Distance
5848 km

Book with confidence

Compare flights from San Francisco to Medellín easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from San Francisco to Medellín. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to José María Córdova Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from San Francisco Intl. to José María Córdova Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from San Francisco Intl. (SFO) to José María Córdova Intl. (MDE)

The easiest way to view the best deals on flights from San Francisco to Medellín today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from San Francisco Intl. to José María Córdova Intl. start at just £478 and range up to £868.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near San Francisco and Medellín
  • booking your flight during May, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your San Francisco to Medellín flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from San Francisco Intl. to José María Córdova Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from San Francisco to Medellín easily and book with confidence

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*Available to Expedia members.