£293 Cheap Flights from Mexico City (MEX) to Santiago (SCL)

View £293 flight on Fri, 14 Aug 2026Opens in a new window

Popular airlines from Benito Juarez International Airport (MEX) to Santiago Intl. Airport (SCL)

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Cheap Flights from Mexico City (MEX) to Santiago (SCL)

Prices were available within the past 7 days and start at £293 for one-way flights and £553 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Fri, 1 May - Thu, 7 May
MEX
Mexico City
SCL
Santiago
£553 Return, found 14 hours ago
£553
Return
found 14 hours ago
Select avianca flight, departing Fri, 1 May from Mexico City to Santiago, returning Thu, 7 May, priced at £553 found 14 hours ago
Copa
Sun, 17 May - Sun, 24 May
MEX
Mexico City
SCL
Santiago
£554 Return, found 22 hours ago
£554
Return
found 22 hours ago
Select Copa flight, departing Sun, 17 May from Mexico City to Santiago, returning Sun, 24 May, priced at £554 found 22 hours ago
avianca
Fri, 1 May - Thu, 7 May
MEX
Mexico City
SCL
Santiago
£567 Return, found 14 hours ago
£567
Return
found 14 hours ago
Select avianca flight, departing Fri, 1 May from Mexico City to Santiago, returning Thu, 7 May, priced at £567 found 14 hours ago
avianca
Fri, 1 May - Thu, 7 May
MEX
Mexico City
SCL
Santiago
£568 Return, found 14 hours ago
£568
Return
found 14 hours ago
Select avianca flight, departing Fri, 1 May from Mexico City to Santiago, returning Thu, 7 May, priced at £568 found 14 hours ago
avianca
Fri, 15 May - Fri, 22 May
MEX
Mexico City
SCL
Santiago
£571 Return, found 22 hours ago
£571
Return
found 22 hours ago
Select avianca flight, departing Fri, 15 May from Mexico City to Santiago, returning Fri, 22 May, priced at £571 found 22 hours ago
Copa
Sun, 17 May - Sun, 24 May
MEX
Mexico City
SCL
Santiago
£581 Return, found 22 hours ago
£581
Return
found 22 hours ago
Select Copa flight, departing Sun, 17 May from Mexico City to Santiago, returning Sun, 24 May, priced at £581 found 22 hours ago
Copa
Sun, 17 May - Sun, 24 May
MEX
Mexico City
SCL
Santiago
£583 Return, found 22 hours ago
£583
Return
found 22 hours ago
Select Copa flight, departing Sun, 17 May from Mexico City to Santiago, returning Sun, 24 May, priced at £583 found 22 hours ago
LATAM Airlines Group
Thu, 14 May - Thu, 21 May
MEX
Mexico City
SCL
Santiago
£590 Return, found 22 hours ago
£590
Return
found 22 hours ago
Select LATAM Airlines Group flight, departing Thu, 14 May from Mexico City to Santiago, returning Thu, 21 May, priced at £590 found 22 hours ago
Aeromexico
Sat, 13 Feb - Wed, 10 Mar
MEX
Mexico City
SCL
Santiago
£630 Return, found 4 days ago
£630
Return
found 4 days ago
Select Aeromexico flight, departing Sat, 13 Feb from Mexico City to Santiago, returning Wed, 10 Mar, priced at £630 found 4 days ago
American Airlines
Sun, 18 Oct - Fri, 30 Oct
MEX
Mexico City
SCL
Santiago
£1,147 Return, found 7 hours ago
£1,147
Return
found 7 hours ago
Select American Airlines flight, departing Sun, 18 Oct from Mexico City to Santiago, returning Fri, 30 Oct, priced at £1,147 found 7 hours ago

Find the cheapest month to fly from Mexico City (MEX) to Santiago (SCL)

August is typically the cheapest month to fly

From £340 - £600 per traveller.

Frequently asked questions

How much is a flight from Benito Juárez Intl. Airport to Santiago International Airport?
The lowest price advertised for a round-trip journey from Mexico City Intl. Airport (MEX) to Santiago International Airport is £553. But you better act quick. This figure is based on fares listed within the last 7 days on Expedia for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from Mexico City Intl. Airport (MEX) to SCL?
When it comes to cancellation fees, each airline has a different set of terms and conditions. If you decide to cancel your escape, head to our Customer Service Portal.
How do I find cheap flights from MEX to Santiago International Airport that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Mexico City Intl. Airport (MEX) to Nuevo Pudahuel Airport flights, you'll see a "no change fees" filter for you to select.
How far is the flight from MEX to Nuevo Pudahuel Airport?
With a flight distance of 6,600 kilometres from Mexico Airport (MEX) to Arturo Merino Benitez Airport (SCL) (SCL), this is a long journey. Ensure that you stay hydrated and move around the cabin every so often.
Which airlines fly direct from Benito Juárez Intl. Airport to Nuevo Pudahuel Airport?
Many travellers opt to fly with LATAM Airlines (LA) from Mexico Airport to SCL. It offers 30 flights every month, so you can easily find a flight time that works for you. Offering 21 flights every month along this route, Aeromexico (AM) is another traveller favourite.
Are Mexico Airport to Nuevo Pudahuel Airport flight tickets cheaper when they're purchased at the last minute?
Booking last minute from MEX to Arturo Merino Benitez Airport (SCL) can be hit-or-miss. You may be able to find a bargain, but then again, you could miss out entirely! If you'd prefer to play it safe and start your trip planning early, Expedia compares flight deals up to 12 months in advance. Just bear in mind that not all airlines release their prices so far in advance. Our top tip? Check back often as prices are updated regularly.

Frequently asked questions

How much does a flight from Mexico City (MEX-Mexico City Intl.) to Santiago (SCL-Arturo Merino Benitez) cost?
One-way flights typically cost between £435 and £3,001 and return flights often range between £1,112 and £6,004. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Anaa (AAA) to Toronto, ON (YYZ-Pearson Intl.) ticket fares go up or down.
Which airlines fly direct from Mexico City (MEX-Mexico City Intl.) to Santiago (SCL-Arturo Merino Benitez)?
Enter MEX to SCL and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Mexico City (MEX-Mexico City Intl.) to Santiago (SCL-Arturo Merino Benitez)?
To find a cheap flight from Mexico City (MEX-Mexico City Intl.) to Santiago (SCL-Arturo Merino Benitez), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Mexico City (MEX-Mexico City Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The best airline to fly with from Mexico City (MEX-Mexico City Intl.) (MEX) to Santiago (SCL-Arturo Merino Benitez) (SCL) will differ from traveller to traveller. If you like to fly early, LA offers early morning flights. If price is the most important factor, LA typically offers the lowest fares. AM offers the most daily flights from Mexico City (MEX-Mexico City Intl.) (MEX) to Santiago (SCL-Arturo Merino Benitez) (SCL), which is brilliant if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Mexico City (MEX-Mexico City Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Mexico City (MEX-Mexico City Intl.) to Santiago (SCL-Arturo Merino Benitez)?
There is approximately 1 nonstop flight per day from Mexico City Intl. (MEX) to Arturo Merino Benitez (SCL). For even more choice, look at flights that include layovers. You'll find around 59 connecting flights per day. Some common connection points include Jorge Chavez Intl. (LIM), Cancun Intl. (CUN), and George Bush Intercontinental (IAH).
What is the earliest flight from Mexico City (MEX-Mexico City Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The earliest flight from Mexico City Intl. (MEX) to Santiago (SCL-Arturo Merino Benitez) typically departs at approximately 12:05 AM local time, operated by Aeromexico and Aerolineas Argentinas. This is a seasonal service active in August. An early departure like this can help maximise your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Mexico City (MEX-Mexico City Intl.) to Santiago (SCL-Arturo Merino Benitez)?
You'll typically find the most flights from Mexico City (MEX-Mexico City Intl.) to Santiago (SCL-Arturo Merino Benitez) on a Friday, with around 36 flights available. This gives you a good selection of options for your travel plans. Major airlines on this route include Aeromexico, Copa, and United.
What are the most popular departure times for flights from Mexico City (MEX-Mexico City Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The most popular departure times for flights from Mexico City (MEX-Mexico City Intl.) to Santiago (SCL-Arturo Merino Benitez) are in the early morning, from 3am to 6am. About 19% of passengers prefer this time window. Many major carriers, including CM and AV, offer flights during this window. These times work well because you can often find overnight flights that allow you to arrive at your destination early in the morning, ready to start your day.
How long does it take to fly from Mexico City (MEX-Mexico City Intl.) to Santiago (SCL-Arturo Merino Benitez)?
A nonstop flight from MEX to SCL typically takes around 8 hours 50 minutes, covering approximately 4,099 miles. Connecting flights on this route usually add 2 hours 40 minutes to your travel time. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Mexico City (MEX-Mexico City Intl.) to Santiago (SCL-Arturo Merino Benitez)?
Select the "Business class" and "First class" filters when looking for MEX to SCL flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How much is a business class flight from Mexico City (MEX-Mexico City Intl.) to Santiago (SCL-Arturo Merino Benitez)?
A direct, return business class ticket from Mexico City (MEX) to Santiago (SCL) typically costs between £3,594 - £6,215. A non-stop, one-way business class flight is usually around £1,547 - £1,585. Prices often fluctuate based on seasonality and how early you book. You may also be able to find a cheaper business class journey between Anaa (AAA) (AAA) to Toronto, ON (YYZ-Pearson Intl.) (YYZ) if you opt for a connecting flight.
How do I earn miles on a Mexico City (MEX-Mexico City Intl.) to Santiago (SCL-Arturo Merino Benitez) flight with Expedia?
It's easy to earn miles on a Mexico City (MEX-Mexico City Intl.) to Santiago (SCL-Arturo Merino Benitez) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Santiago from Mexico City Intl. (MEX)?
From Mexico City Intl. (MEX), you can fly into Cibao Intl. (STI) and Arturo Merino Benitez (SCL) in Santiago. Some flights may connect through major hubs like O'Hare Intl. (ORD), Dallas-Fort Worth Intl. (DFW), George Bush Intercontinental (IAH) before reaching Santiago. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Mexico City (MEX-Mexico City Intl.) to Santiago (SCL-Arturo Merino Benitez) at the last minute?
Typically, booking a last minute flight from Mexico City (MEX-Mexico City Intl.) to Santiago (SCL-Arturo Merino Benitez) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Mexico City (MEX-Mexico City Intl.) to Santiago (SCL-Arturo Merino Benitez) flight and hotel package?
Securing a Mexico City (MEX-Mexico City Intl.) to Santiago (SCL-Arturo Merino Benitez) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Mexico City (MEX-Mexico City Intl.) to Santiago (SCL-Arturo Merino Benitez)?
If you booked your Mexico City (MEX-Mexico City Intl.) to Santiago (SCL-Arturo Merino Benitez) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Mexico City Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
American Airlines, Copa, Delta, LATAM Airlines Group, avianca
Return price
£553
Distance
6558 km
Average flight time
8 hours 40 mins

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