£557 Cheap Flights from Cape Town (CPT) to Santiago (SCL)

View £557 flight on Sat, 5 Sept 2026Opens in a new window

Flight 1

Popular airlines from Cape Town Intl. Airport (CPT) to Santiago Intl. Airport (SCL)

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Cheap Flights from Cape Town (CPT) to Santiago (SCL)

Prices were available within the past 7 days and start at £557 for one-way flights and £650 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Sat, 31 Oct - Sun, 8 Nov
CPT
Cape Town
SCL
Santiago
£650 Return, found 3 days ago
£650
Return
found 3 days ago
Select LATAM Airlines Group flight, departing Sat, 31 Oct from Cape Town to Santiago, returning Sun, 8 Nov, priced at £650 found 3 days ago
LATAM Airlines Group
Mon, 26 Oct - Sun, 8 Nov
CPT
Cape Town
SCL
Santiago
£686 Return, found 3 days ago
£686
Return
found 3 days ago
Select LATAM Airlines Group flight, departing Mon, 26 Oct from Cape Town to Santiago, returning Sun, 8 Nov, priced at £686 found 3 days ago
LATAM Airlines Group
Sun, 1 Nov - Sun, 8 Nov
CPT
Cape Town
SCL
Santiago
£743 Return, found 3 days ago
£743
Return
found 3 days ago
Select LATAM Airlines Group flight, departing Sun, 1 Nov from Cape Town to Santiago, returning Sun, 8 Nov, priced at £743 found 3 days ago
LATAM Airlines Group
Sat, 31 Oct - Mon, 9 Nov
CPT
Cape Town
SCL
Santiago
£750 Return, found 3 days ago
£750
Return
found 3 days ago
Select LATAM Airlines Group flight, departing Sat, 31 Oct from Cape Town to Santiago, returning Mon, 9 Nov, priced at £750 found 3 days ago
LATAM Airlines Group
Sun, 1 Nov - Sat, 7 Nov
CPT
Cape Town
SCL
Santiago
£768 Return, found 3 days ago
£768
Return
found 3 days ago
Select LATAM Airlines Group flight, departing Sun, 1 Nov from Cape Town to Santiago, returning Sat, 7 Nov, priced at £768 found 3 days ago
LATAM Airlines Group
Mon, 26 Oct - Mon, 9 Nov
CPT
Cape Town
SCL
Santiago
£786 Return, found 3 days ago
£786
Return
found 3 days ago
Select LATAM Airlines Group flight, departing Mon, 26 Oct from Cape Town to Santiago, returning Mon, 9 Nov, priced at £786 found 3 days ago
United
Wed, 28 Oct - Sat, 7 Nov
CPT
Cape Town
SCL
Santiago
£1,043 Return, found 3 days ago
£1,043
Return
found 3 days ago
Select United flight, departing Wed, 28 Oct from Cape Town to Santiago, returning Sat, 7 Nov, priced at £1,043 found 3 days ago
South African Airways
Mon, 8 Jun - Sun, 14 Jun
CPT
Cape Town
SCL
Santiago
£1,073 Return, found 9 hours ago
£1,073
Return
found 9 hours ago
Select South African Airways flight, departing Mon, 8 Jun from Cape Town to Santiago, returning Sun, 14 Jun, priced at £1,073 found 9 hours ago
Qatar Airways
Mon, 8 Jun - Sun, 14 Jun
CPT
Cape Town
SCL
Santiago
£1,367 Return, found 9 hours ago
£1,367
Return
found 9 hours ago
Select Qatar Airways flight, departing Mon, 8 Jun from Cape Town to Santiago, returning Sun, 14 Jun, priced at £1,367 found 9 hours ago
KLM
Tue, 12 May - Tue, 19 May
CPT
Cape Town
SCL
Santiago
£1,477 Return, found 3 days ago
£1,477
Return
found 3 days ago
Select KLM flight, departing Tue, 12 May from Cape Town to Santiago, returning Tue, 19 May, priced at £1,477 found 3 days ago

Frequently asked questions

How do I find cheap flights from Cape Town (CPT-Cape Town Intl.) to Santiago (SCL-Arturo Merino Benitez)?
To find a cheap flight from Cape Town (CPT-Cape Town Intl.) to Santiago (SCL-Arturo Merino Benitez), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Cape Town (CPT-Cape Town Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Cape Town (CPT-Cape Town Intl.) to Santiago (SCL-Arturo Merino Benitez)?
There are approximately 12 connecting flights per day from Cape Town Intl. (CPT) to Arturo Merino Benitez (SCL). Some common connection points include O.R. Tambo Intl. (JNB), Hamad Intl. (DOH), and Guarulhos - Governor Andre Franco Montoro Intl. (GRU).
What is the earliest flight from Cape Town (CPT-Cape Town Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The earliest flight from Cape Town Intl. (CPT) to Arturo Merino Benitez (SCL) typically departs at approximately 6:05 AM local time. This service is operated by Airlink and LATAM Airlines. This is a seasonal service active in November. An early departure like this can help you maximise your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Cape Town (CPT-Cape Town Intl.) to Santiago (SCL-Arturo Merino Benitez)?
You'll typically find the most flights from Cape Town (CPT-Cape Town Intl.) to Santiago (SCL-Arturo Merino Benitez) on a Tuesday, with around 21 flights available. This gives you plenty of options for your travel plans. Major airlines on this route include British Airways, Airlink, and KLM. With around 24% more flights on Tuesdays compared to other days, you'll have a good selection of departure times.
What are the most popular departure times for flights from Cape Town (CPT-Cape Town Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The most popular departure times for flights from Cape Town (CPT-Cape Town Intl.) to Santiago (SCL-Arturo Merino Benitez) are between 12pm and 3pm. Approximately 46% of passengers prefer this time window. Many major carriers, including South African Airways, LATAM Airlines and Qatar Airways, offer flights during this window. This timing works well for many travellers, allowing for a midday departure.
How long does it take to fly from Cape Town (CPT-Cape Town Intl.) to Santiago (SCL-Arturo Merino Benitez)?
Flights from CPT to SCL with one stop typically take around 18 hours, covering approximately 4,950 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Cape Town (CPT-Cape Town Intl.) to Santiago (SCL-Arturo Merino Benitez)?
Select the "Business class" and "First class" filters when looking for CPT to SCL flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Cape Town (CPT-Cape Town Intl.) to Santiago (SCL-Arturo Merino Benitez) flight with Expedia?
It's easy to earn miles on a Cape Town (CPT-Cape Town Intl.) to Santiago (SCL-Arturo Merino Benitez) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Santiago from Cape Town Intl. (CPT)?
If you're planning to travel to Santiago from Cape Town Intl. (CPT), you can fly into Arturo Merino Benitez (SCL) Some flights may connect through major hubs like Schiphol (AMS), Guarulhos - Governor Andre Franco Montoro Intl. (GRU), Hamad Intl. (DOH) before reaching Santiago. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Cape Town (CPT-Cape Town Intl.) to Santiago (SCL-Arturo Merino Benitez) at the last minute?
Typically, booking a last minute flight from Cape Town (CPT-Cape Town Intl.) to Santiago (SCL-Arturo Merino Benitez) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Cape Town (CPT-Cape Town Intl.) to Santiago (SCL-Arturo Merino Benitez) flight and hotel package?
Securing a Cape Town (CPT-Cape Town Intl.) to Santiago (SCL-Arturo Merino Benitez) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Cape Town (CPT-Cape Town Intl.) to Santiago (SCL-Arturo Merino Benitez)?
If you booked your Cape Town (CPT-Cape Town Intl.) to Santiago (SCL-Arturo Merino Benitez) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Cape Town Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Iberia, KLM, Qatar Airways, Turkish Airlines
Return price
£649
Distance
7919 km

Book with confidence

Compare flights from Cape Town to Santiago easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Cape Town to Santiago. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Arturo Merino Benitez in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Cape Town Intl. to Arturo Merino Benitez.  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Cape Town Intl. (CPT) to Arturo Merino Benitez (SCL)

The easiest way to view the best deals on flights from Cape Town to Santiago today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Cape Town Intl. to Arturo Merino Benitez start at just £650 and range up to £1,477.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Cape Town and Santiago
  • booking your flight during October, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Cape Town to Santiago flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Cape Town Intl. to Arturo Merino Benitez for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Cape Town to Santiago easily and book with confidence

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*Available to Expedia members.