Title: Cheap Flights from São Tomé and Príncipe from £252 - Expedia.co.uk ![](https://a.travel-assets.com/travel-assets-manager/32a5a1b7-682e-4c22-a8ab-4b736795e0ea/expedia_fallback.webp?impolicy=fcrop&w=1200&h=500&q=medium) # Cheap Flights from São Tomé and Príncipe from £252 [View £252 flight on Wed, 29 Oct 2025](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:TMS,to:LIS,departure:29/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:251.90&airProductToken=AQo3CjUI1KABEgQxNTI4GJOTASCLkgEokNb7AjCx2vsCOEVAAFgBagdESVNDSU5UcghFTDBEU0kwNBIKCAEQARgBKgJUUBgBIgQIARABKAIoAygEMA0) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only [São Tomé and Príncipe Travel Guide](https://expedia.co.uk/Sao-Tome-And-Principe.dx156)[São Tomé and Príncipe Hotels](https://expedia.co.uk/Destinations-In-Sao-Tome-And-Principe.d156.Hotel-Destinations)[São Tomé and Príncipe Car Hire](https://expedia.co.uk/Destinations-In-Sao-Tome-And-Principe.d156.Car-Hire-Destinations)[São Tomé and Príncipe Holidays](https://expedia.co.uk/Sao-Tome-And-Principe.d156.Holidays-City-Breaks) ## Popular airlines from São Tomé and Príncipe - ![TAP Portugal](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_TP.svg) TAP Portugal - ![Hahn Air Systems](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_H1.svg) Hahn Air Systems - ![Ethiopian Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_ET.svg) Ethiopian Airlines - ![APG Distribution System](https://forever.travel-assets.com/flex/flexmanager/images/2025/03/25/landing_airline_sq_logo_A1.svg) APG Distribution System - ![ASKY](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_KP.svg) ASKY - ## Plan, book, fly with confidence - ### Be in the know Get alerts if flight prices drop or rise\* - ### Book smarter Save up to 25% on select hotels after you book a flight\* - ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheapest flights from São Tomé and Príncipe These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Fri, 17 Apr - Sat, 6 Jun TMS São Tomé Island LIS Lisbon £419 Return found 5 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:TMS,to:LIS,departure:17/04/2026TANYT&leg2=from:LIS,to:TMS,departure:06/06/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:418.40&airProductToken=AQo3CjUI1KABEgQxNTI4GJOTASCLkgEovM6KAzDE0ooDOFRAAFgBagdESVNDSU5UcghUTDBEU0k4MAo3CjUI1KABEgQxNTMxGIuSASCTkwEo4PyOAzDw_44DOFRAAFgBagdESVNDSU5UcghUTDBEU0k4MBIKCAEQARgBKgJUUBgBIgQIARABKAIoAygEMA0) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Sat, 30 May - Sat, 6 Jun TMS São Tomé Island LIS Lisbon £445 Return found 21 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:TMS,to:LIS,departure:30/05/2026TANYT&leg2=from:LIS,to:TMS,departure:06/06/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:445.00&airProductToken=AQo3CjUI1KABEgQxNTMyGJOTASCLkgEoj7OOAzCkto4DOEVAAFgBagdESVNDSU5UcghFTDBEU0k4MAo3CjUI1KABEgQxNTMxGIuSASCTkwEo4PyOAzDw_44DOFRAAFgBagdESVNDSU5UcghUTDBEU0k4MBIKCAEQARgBKgJUUBgBIgQIARABKAIoAygEMA0) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Fri, 5 Dec - Wed, 14 Jan TMS São Tomé Island LIS Lisbon £447 Return found 5 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:TMS,to:LIS,departure:05/12/2025TANYT&leg2=from:LIS,to:TMS,departure:14/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:446.40&airProductToken=AQo3CjUI1KABEgQxNTI4GJOTASCLkgEosPb-AjDR-v4COFRAAFgBagdESVNDSU5UcghUTDBEU0k4MAo3CjUI1KABEgQxNTI3GIuSASCTkwEov7OCAzC9t4IDOEVAAFgBagdESVNDSU5UcghFTDBEU0k4MBIKCAEQARgBKgJUUBgBIgQIARABKAIoAygEMA0) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Fri, 17 Apr - Sat, 6 Jun TMS São Tomé Island LIS Lisbon £472 Return found 5 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:TMS,to:LIS,departure:17/04/2026TANYT&leg2=from:LIS,to:TMS,departure:06/06/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:471.50&airProductToken=AQo2CjQI1KABEgQxNTI4GJOTASCLkgEovM6KAzDE0ooDOFRAAFgBagZCQVNJTlRyCFRMMEJTSTgwCjYKNAjUoAESBDE1MzEYi5IBIJOTASjg_I4DMPD_jgM4VEAAWAFqBkJBU0lOVHIIVEwwQlNJODASCggBEAEYASoCVFAYASIECAEQASgCKAMoBDAN) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Sat, 28 Mar - Sat, 25 Apr TMS São Tomé Island LIS Lisbon £473 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:TMS,to:LIS,departure:28/03/2026TANYT&leg2=from:LIS,to:TMS,departure:25/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:472.90&airProductToken=AQo3CjUI1KABEgQxNTMyGJOTASCLkgEo4e6IAzDx8YgDOEVAAFgBagdESVNDSU5UcghFTDBEU0k4MAo3CjUI1KABEgQxNTMxGIuSASCTkwEooKSLAzCwp4sDOEVAAFgBagdESVNDSU5UcghFTDBEU0k4MBIKCAEQARgBKgJUUBgBIgQIARABKAIoAygEMA0) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Wed, 18 Mar - Wed, 25 Mar TMS São Tomé Island LIS Lisbon £476 Return found 11 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:TMS,to:LIS,departure:18/03/2026TANYT&leg2=from:LIS,to:TMS,departure:25/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:475.10&airProductToken=AQo3CjUI1KABEgQxNTI4GJOTASCLkgEokP2HAzCxgYgDOE9AAFgBagdESVNDSU5UcghPRjBEU0lPQQo3CjUI1KABEgQxNTI3GIuSASCTkwEo_8aIAzD9yogDOFVAAFgBagdESVNDSU5UcghVTDBEU0k3MBIKCAEQARgBKgJUUBgBIgQIARABKAIoAygEMA0) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Wed, 18 Mar - Wed, 25 Mar TMS São Tomé Island LIS Lisbon £476 Return found 11 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:TMS,to:LIS,departure:18/03/2026TANYT&leg2=from:LIS,to:TMS,departure:25/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:475.60&airProductToken=AQo4CjYI1KABEgQxNTI4GJOTASCLkgEokP2HAzCxgYgDOFRAAFgBaghESVNDT1VOVHIIVEwwRFNJODAKOAo2CNSgARIEMTUyNxiLkgEgk5MBKP_GiAMw_cqIAzhVQABYAWoIRElTQ09VTlRyCFVMMERTSTcwEgoIARABGAEqAlRQGAEiBAgBEAEoAigDKAQwAQ) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Fri, 7 Nov - Sun, 23 Nov TMS São Tomé Island LIS Lisbon £490 Return found 1 day ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:TMS,to:LIS,departure:07/11/2025TANYT&leg2=from:LIS,to:TMS,departure:23/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:489.87&airProductToken=AQo4CjYI1KABEgQxNTI4GJOTASCLkgEosLv8AjDRv_wCOFVAAFgBaghESVNDT1VOVHIIVUwwRFNJNzAKOAo2CNSgARIEMTUyNxiLkgEgk5MBKL_q_QIwve79AjhUQABYAWoIRElTQ09VTlRyCFRMMERTSTgwEgoIARABGAEqAlRQGAEiBAgBEAEoAigDKAQwAQ) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Sat, 30 May - Sat, 6 Jun TMS São Tomé Island LIS Lisbon £498 Return found 21 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:TMS,to:LIS,departure:30/05/2026TANYT&leg2=from:LIS,to:TMS,departure:06/06/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:498.00&airProductToken=AQo2CjQI1KABEgQxNTMyGJOTASCLkgEoj7OOAzCkto4DOEVAAFgBagZCQVNJTlRyCEVMMEJTSTgwCjYKNAjUoAESBDE1MzEYi5IBIJOTASjg_I4DMPD_jgM4VEAAWAFqBkJBU0lOVHIIVEwwQlNJODASCggBEAEYASoCVFAYASIECAEQASgCKAMoBDAN) ![Ethiopian Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/ET.gif) Wed, 24 Sept - Wed, 1 Oct TMS São Tomé Island LAD Luanda £934 Return found 1 day ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:TMS,to:LAD,departure:24/09/2025TANYT&leg2=from:LAD,to:TMS,departure:01/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:933.80&airProductToken=AQp8CikIxagBEgQxMDIxGJOTASCrqAEopMb4AjDgxvgCOEhAAFgBcgVIUFgzTQonCMWoARIDOTI1GKuoASDgGCjGyPgCMLPL-AI4UUABWAFyBVFFU0dBCiYIxagBEgM4NTEY4BggixgosNH4AjDN0_gCOFFAAVgBcgVRRVNHQQp8CiYIxagBEgM4NTAYixgg4Bgo4pf5AjD_mfkCOFFAAFgBcgVRRVNHQQonCMWoARIDOTU1GOAYIKuoASjtn_kCMNqi-QI4UUABWAFyBVFFU0dBCikIxagBEgQxMDIwGKuoASCTkwEo6KT5AjCkpfkCOEhAAVgBcgVIUFgzTRIKCAEQARgBKgJFVBgBIgQIARABKAIoAygEMAE) ## How to Find Cheap Flights from São Tomé and Príncipe #### How much is a flight from São Tomé and Príncipe?        This week, flights from São Tomé and Príncipe are available between £419–£934.  #### How to find cheap flights from São Tomé and Príncipe? Expedia makes it easy to compare cheap flights from São Tomé and Príncipe to many destinations. Check out excellent deals on both domestic and international flights from São Tomé and Príncipe. Once you select an offer, use our filters and sort by “Price (Lowest)” to see the cheapest and most suitable options.  #### How can I get the best deal on flights from São Tomé and Príncipe? Expedia gives you access to all the hottest deals on plane tickets so you can get the most amount of value for the lowest price possible. An excellent strategy for finding the best deal on flights is to be flexible with your dates. For each offer, you can compare prices for similar time frames using our “Show flexible dates” feature. Depending on your destination, direct flights from São Tomé and Príncipe may be more expensive. Airlines with strict bag policies or fees can also impact your costs.  #### What is the best airline to fly from São Tomé and Príncipe? At Expedia, we give you all the available options from our reputable partners. Select the airline that best suits your preferences and membership loyalties. You can fly from São Tomé and Príncipe with: TAP Portugal, ASKY, Ethiopian Airlines.  #### What is the best month to fly from São Tomé and Príncipe? Prices on plane tickets vary considerably throughout the year due to seasonal demand. Historically, the cheapest time to buy flights from São Tomé and Príncipe airport(s) is April.  #### When is the best time to book flights from São Tomé and Príncipe? ARC & Expedia Group historical data suggests that booking flights three weeks before departure and on a weekend, usually on a Sunday, can save you up to 20% on your fare. \* #### Are there any last-minute flights from São Tomé and Príncipe? Expedia is the place to find last-minute flights from São Tomé and Príncipe, making it easy for you to compare prices on flights in the near future for different combinations of travel dates and from multiple airlines. We source the best deals for you and display the best offers available over the next two weeks.  #### Why book with Expedia? Booking flights from São Tomé and Príncipe with Expedia is the obvious choice to get low prices, save money and see more value for every pound spent. We show you the best deals happening right now and provide a vast inventory of airlines and flight routes to choose from. You can customise your journey to your timeline, route preferences, budget, rewards programmes and more. Not only will you get a stellar deal, but you’ll also get rewards points back and the opportunity for additional discounts when bundling with a hotel or car hire. #### Can I change/cancel my flight?  Some flights can be changed or cancelled, but fees and refunds will depend on the unique terms of your flight agreement. Airlines have different rules and restrictions for exchanging or refunding flights. For more information, go to your itinerary or visit our customer service portal. We recommend choosing flights with no change fees for maximum flexibility. Filter by “Flexible change policies” to see flights with no change fees. \**Data specialists from both ARC and Expedia Group analyzed ARC’s global flight data to distill actionable information to help people save money on travel. While it’s impossible to guarantee when to find the lowest prices, after examining the variables, we were able to observe trends. Best day of the week to book and travel recommendation is based on average round-trip ticket prices for January through early October, for both 2019 and 2020, sourced from ARC’s global airline sales database.*. ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Other - [5 Star Hotels in São Tomé Island](https://www.expedia.co.uk/5Star-Sao-Tome-Island-Hotels.s50-0-d3486.Travel-Guide-Filter-Hotels) - [Hotels near Jale Beach](https://www.expedia.co.uk/Jale-Beach-Hotels.0-l553248621532481755-0.Travel-Guide-Filter-Hotels) - [Farmstay in São Tomé Island](https://www.expedia.co.uk/Sao-Tome-Island-Agritourism.d3486-aaAgritourism.Travel-Guide-Accommodation) - [Castles in São Tomé Island](https://www.expedia.co.uk/Sao-Tome-Island-Castles.d3486-aaCastles.Travel-Guide-Accommodation) - [Chalets in São Tomé Island](https://www.expedia.co.uk/Sao-Tome-Island-Chalets.d3486-aaChalets.Travel-Guide-Accommodation) - [Cottages in São Tomé Island](https://www.expedia.co.uk/Sao-Tome-Island-Cottages.d3486-aaCottages.Travel-Guide-Accommodation) - [Resorts in São Tomé Island](https://www.expedia.co.uk/Sao-Tome-Island-Hotel-Resorts.d3486-aaHotelResorts.Travel-Guide-Accommodation) - [All-Inclusive Hotels in São Tomé Island](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-All-Inclusive-Hotel.0-0-d3486-tAllInclusiveHotel.Travel-Guide-Filter-Hotels) - [Beach Resorts & in São Tomé Island](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Beach-Hotels.0-0-d3486-tBeachHotels.Travel-Guide-Filter-Hotels) - [Boutique Hotels in São Tomé Island](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Boutique-Hotel.0-0-d3486-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in São Tomé Island](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Budget-Hotels.0-0-d3486-tBudgetHotels.Travel-Guide-Filter-Hotels) - [Family-Friendly Hotels in São Tomé Island](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Family-Friendly-Hotel.0-0-d3486-tFamilyFriendlyHotel.Travel-Guide-Filter-Hotels) - [Green Hotels in São Tomé Island](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Green-Sustainable.0-0-d3486-tGreenSustainable.Travel-Guide-Filter-Hotels) - [Hotels with a Bar in São Tomé Island](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Hotel-With-A-Bar.0-0-d3486-thotelwithabar.Travel-Guide-Filter-Hotels) - [Hotels with Restaurant in São Tomé Island](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Hotel-With-Restaurant.0-0-d3486-thotelwithrestaurant.Travel-Guide-Filter-Hotels) - [Hotels with Pool in São Tomé Island](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Hotels-With-Pool.0-0-d3486-tHotelswithPool.Travel-Guide-Filter-Hotels) - [Luxury Hotels in São Tomé Island](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Luxury-Hotel.0-0-d3486-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pestana Group Hotels in São Tomé Island](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Pestana-Group.0-0-d3486--bPestanaGroup.Travel-Guide-Filter-Hotels) - [São Tomé Island Hotels](https://www.expedia.co.uk/Sao-Tome-Island-Hotels.d3486.Travel-Guide-Hotels) - [Palaces in São Tomé Island](https://www.expedia.co.uk/Sao-Tome-Island-Palaces.d3486-aaPalaces.Travel-Guide-Accommodation) - [Pousadas in São Tomé Island](https://www.expedia.co.uk/Sao-Tome-Island-Pousadas.d3486-aaPousadas.Travel-Guide-Accommodation) - [Town Houses in São Tomé Island](https://www.expedia.co.uk/Sao-Tome-Island-Town-Houses.d3486-aaTownHouses.Travel-Guide-Accommodation) - [Flights to São Tomé Island](https://www.expedia.co.uk/Cheap-Flights-To-Sao-Tome-Island.d3486.Travel-Guide-Flights) - [Jale Beach](https://www.expedia.co.uk/Jale-Beach-Sao-Tome-and-Principe.d553248621532481755.Attraction) - [São Tomé Island Holidays](https://www.expedia.co.uk/Sao-Tome-Island.d3486.Holidays-City-Breaks) - [Visit São Tomé Island](https://www.expedia.co.uk/Sao-Tome-Island.dx3486) - [Golf Holiday Packages São Tomé Island](https://www.expedia.co.uk/lp/theme-holidays/golf-holidays/3486/Sao-Tome-Island) - [Car hire near São Tomé Island](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Sao-Tome-Island.d3486.Car-Hire-Guide) - [Niconico Rent A Car Rental Cars in São Tomé Island](https://www.expedia.co.uk/NICONICO-Rent-A-Car-Car-Rentals-In-Sao-Tome-Island.d3486-c1134.Car-Rental-Guide-Suppliers) - [Things to do in São Tomé Island](https://www.expedia.co.uk/Things-To-Do-In-Sao-Tome-Island.d3486.Travel-Guide-Activities) \*Available to Expedia members.