Title: Hotels in Guadalupe - Best Guadalupe Hotels from £35 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Guadalupe](https://expedia.co.uk/Guadalupe-Holiday-Rentals.d899031598492831744.Travel-Guide-HolidayRentals)[Guadalupe Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Guadalupe.d899031598492831744.Car-Hire-Guide)[Guadalupe Holidays](https://expedia.co.uk/Guadalupe.d899031598492831744.Holidays-City-Breaks) ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Guadalupe Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Guadalupe%2C+Lobata%2C+S%C3%A3o+Tom%C3%A9+and+Pr%C3%ADncipe®ionId=899031598492831744&latLong=0.368612%2C6.620543&adults=2&startDate=2026-04-17&d1=2026-04-17&endDate=2026-04-19&d2=2026-04-19&amenities=POOL) ## Check prices for these dates Tonight [3 Apr - 4 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=899031598492831744&startDate=2026-04-03&endDate=2026-04-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [4 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=899031598492831744&startDate=2026-04-04&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=899031598492831744&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [10 Apr - 12 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=899031598492831744&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Guadalupe hotels ![On the beach](https://images.trvl-media.com/lodging/23000000/22710000/22709500/22709437/c133a29b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/23000000/22710000/22709500/22709437/27e015d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room | Minibar, individually decorated, free WiFi](https://images.trvl-media.com/lodging/23000000/22710000/22709500/22709437/61594a9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/23000000/22710000/22709500/22709437/19a68080.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residêncial Tamarindos [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Residencial-Tamarindos.h22709437.Hotel-Information) Guadalupe 8.6/10 Excellent (14 reviews) "Couldn’t have had better hosts Perfect location for great hikes and waterfalls Many thanks to Marlena and Betty who made our visit memorable x" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Maria £39 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Residencial-Tamarindos.h22709437.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/11000000/10350000/10348400/10348352/d968c0c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk](https://images.trvl-media.com/lodging/11000000/10350000/10348400/10348352/538d97d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk](https://images.trvl-media.com/lodging/11000000/10350000/10348400/10348352/d348c5fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Triple Room | Desk](https://images.trvl-media.com/lodging/11000000/10350000/10348400/10348352/90e86a6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mucumbli Hotel [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Mucumbli-Hotel.h10348352.Hotel-Information) Neves 9.4/10 Exceptional (26 reviews) "A bit rustier than i expected. Beds were SUPER sq " ![Norway](https://a.travel-assets.com/egds/marks/flags/no.svg) Morten £114 includes taxes & fees 16 Apr - 17 Apr [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Mucumbli-Hotel.h10348352.Hotel-Information) ![Standard Cabin | Laptop workspace, bed sheets](https://images.trvl-media.com/lodging/105000000/104080000/104073700/104073683/03f83718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Traditional Cabin, Beach View | Laptop workspace, bed sheets](https://images.trvl-media.com/lodging/105000000/104080000/104073700/104073683/746e5f79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Traditional Cabin, Beach View | Laptop workspace, bed sheets](https://images.trvl-media.com/lodging/105000000/104080000/104073700/104073683/4155521b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104080000/104073700/104073683/9357faa5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### CAMPISMO PRAIA GRANDE [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-CAMPISMO-PRAIA-GRANDE.h104073683.Hotel-Information) Malanza 9.0/10 Wonderful (6 reviews) "A little piece of paradise on an amazing beach. " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) John £44 includes taxes & fees 18 Apr - 19 Apr [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-CAMPISMO-PRAIA-GRANDE.h104073683.Hotel-Information) ![Bungalow | Desk, blackout curtains, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/afa4170d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic House | Living area | TV](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/6ff4185a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/3753b3ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/a9f64453.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Guest House Quinta Natural [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Guest-House-Quinta-Natural.h39486195.Hotel-Information) Trindade 10/10 Exceptional (1 review) £59 includes taxes & fees 4 Apr - 5 Apr [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Guest-House-Quinta-Natural.h39486195.Hotel-Information) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/4766b5b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/74d1540a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/73338a21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/d7eadc09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Praia [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Hotel-Praia.h18900207.Hotel-Information) São Tomé 7.4/10 Good (18 reviews) "Solid, basic hotel. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jonathan £148 includes taxes & fees 16 Apr - 17 Apr [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Hotel-Praia.h18900207.Hotel-Information) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/90eb3603.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, free toiletries, towels](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/184b1734.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/54c71534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/f3251a87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Praia Accommodation [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Praia-Accommodation.h26593135.Hotel-Information) São Tomé 7.4/10 Good (19 reviews) "Great place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daniel £108 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Praia-Accommodation.h26593135.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/dcc8cb9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/d9028277.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/1d47642d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily local cuisine breakfast ](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/6100ac64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omali São Tomé – Principe Collection [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Omali-Sao-Tome.h6762264.Hotel-Information) São Tomé 9.4/10 Exceptional (63 reviews) "Staff was very friendly. Food was excellent. Room was clean and well kept." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) christopher £181 includes taxes & fees 11 Apr - 12 Apr [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Omali-Sao-Tome.h6762264.Hotel-Information) ![Basic Double or Twin Room, Pool View | In-room dining](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/47d5c80e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/c1582a31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/5fe608c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/13076316.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Kenito [](https://www.expedia.co.uk/Sao-Tome-Hotels-Hotel-Kenito.h109258960.Hotel-Information) São Tomé 10/10 Exceptional (3 reviews) "Exceptional" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nii Tetteh £75 includes taxes & fees 21 Apr - 22 Apr [](https://www.expedia.co.uk/Sao-Tome-Hotels-Hotel-Kenito.h109258960.Hotel-Information) ![Buffet](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/92cde547.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/e9aa90a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/cdbf65a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/de137179.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SH Boutique Hotel [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-SH-Boutique-Hotel.h22443247.Hotel-Information) São Tomé 8.6/10 Excellent (10 reviews) "Staff were very accommodating " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Simon Peter £69 includes taxes & fees 2 May - 3 May [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-SH-Boutique-Hotel.h22443247.Hotel-Information) ![Basic Apartment | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/126000000/125770000/125763300/125763221/8fe55824.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Apartment | Blackout curtains, soundproofing, free WiFi](https://images.trvl-media.com/lodging/126000000/125770000/125763300/125763221/895dc7c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Apartment | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/126000000/125770000/125763300/125763221/36adc5ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nour Apartments [](https://www.expedia.co.uk/Sao-Tome-Hotels-Nour-Apartments.h125763221.Hotel-Information) São Tomé £51 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/Sao-Tome-Hotels-Nour-Apartments.h125763221.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/28000000/27100000/27093800/27093780/e065a121.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27100000/27093800/27093780/a9318aac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/28000000/27100000/27093800/27093780/27ea3314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Room, Corner | Hypo-allergenic bedding, individually decorated, individually furnished](https://images.trvl-media.com/lodging/28000000/27100000/27093800/27093780/fc229a53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa de Ferias [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Casa-De-Ferias.h27093780.Hotel-Information) São Tomé 8.8/10 Excellent (6 reviews) "I had a very good time here, got a lot of service and information from the family and in fact almost felt like a family member." ![Sweden](https://a.travel-assets.com/egds/marks/flags/se.svg) Lars Roland £55 includes taxes & fees 3 May - 4 May [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Casa-De-Ferias.h27093780.Hotel-Information) ![Coffee shop](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/5e2988d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Twin Room, City View | Minibar, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/bc77b2ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/c312f98a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/fc496aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Central [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Hotel-Central.h37697027.Hotel-Information) São Tomé 8.2/10 Very good (25 reviews) "Great value. Great location. Ok breakfast. Overall good value for money" ![Norway](https://a.travel-assets.com/egds/marks/flags/no.svg) Elisabeth £48 includes taxes & fees 18 Apr - 19 Apr [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Hotel-Central.h37697027.Hotel-Information) ![Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/121000000/120460000/120451900/120451805/8c12cec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120460000/120451900/120451805/ff5a22d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120460000/120451900/120451805/dfafa2c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120460000/120451900/120451805/ee79bee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Alojamento Santos Silva [](https://www.expedia.co.uk/Sao-Tome-Hotels-Alojamento-Santos-Silva.h120451805.Hotel-Information) São Tomé £264 includes taxes & fees 30 Apr - 1 May [](https://www.expedia.co.uk/Sao-Tome-Hotels-Alojamento-Santos-Silva.h120451805.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/32000000/31070000/31068700/31068683/3a896a59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/32000000/31070000/31068700/31068683/8de5668c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design Triple Room | Minibar, soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/32000000/31070000/31068700/31068683/b9167af0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living room](https://images.trvl-media.com/lodging/32000000/31070000/31068700/31068683/f180a525.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Porcelana Hotel [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Porcelana-Hotel.h31068683.Hotel-Information) Vila Maria 9.6/10 Exceptional (9 reviews) "The place is great, water flows very well and you can get warm for your shower real quick. The hotel manager Leu was helpful and addressed any concerns I had. Again Sipson Tours was great with helping me navigate my accommodation. There is breakfast included and my best part is the fruit options which always part of the meal. The downside is that there is really no variety in the breakfast meal. However, overall I enjoyed my stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linda £35 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Porcelana-Hotel.h31068683.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/6000000/5720000/5710500/5710443/e6ae62f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite | View from room](https://images.trvl-media.com/lodging/6000000/5720000/5710500/5710443/1097ed78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cocktail bar](https://images.trvl-media.com/lodging/6000000/5720000/5710500/5710443/46eca90d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![International cuisine, pool views ](https://images.trvl-media.com/lodging/6000000/5720000/5710500/5710443/6c709953.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pestana Miramar São Tomé [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Pestana-Miramar-Sao-Tome.h5710443.Hotel-Information) São Tomé 7.2/10 Good (46 reviews) "Very helpful and accommodating staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) sandra £145 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Pestana-Miramar-Sao-Tome.h5710443.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/4b0f9c44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside views, open daily](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/b432c63a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, sun-loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/bb670e49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, in-room safe, free WiFi](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/bab15252.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pestana São Tomé [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Pestana-Sao-Tome.h2150447.Hotel-Information) Vila Maria 8.2/10 Very good (81 reviews) "Wonderful stay, great staff, easy, relaxing delightful." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) alexander £199 includes taxes & fees 19 Apr - 20 Apr [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Pestana-Sao-Tome.h2150447.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-17&endDate=2026-04-18®ionId=899031598492831744&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FGuadalupe-Hotels.d899031598492831744.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FGuadalupe-Hotels.d899031598492831744.Travel-Guide-Hotels) ## Learn more about Guadalupe Head to São Nicolau Waterfall and Amelia Lagoon—just two of the sights around Guadalupe. [See all hotels in Guadalupe](https://www.expedia.co.uk/Hotel-Search?startDate=2026-04-17&endDate=2026-04-18&adults=2®ionId=899031598492831744) ![](https://images.trvl-media.com/place/3486/fd939e8d-249d-4718-b69f-6f8d7a35433e.jpg?impolicy=fcrop&w=899&h=199&p=1&q=high) Photo by Fabrice Récalt ## Top Guadalupe Hotel Reviews ![Omali São Tomé – Principe Collection](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/dcc8cb9a_y.jpg) ### Omali São Tomé – Principe Collection 10/10 Excellent "Lovely hotel, staff and location. Very close to airport as well Recommend highly" [](https://expedia.co.uk/Sao-Tome-Island-Hotels-Omali-Sao-Tome.h6762264.Hotel-Information) ![Porcelana Hotel](https://images.trvl-media.com/lodging/32000000/31070000/31068700/31068683/3a896a59_y.jpg) ### Porcelana Hotel 10/10 Excellent "Great value for price. Nice staff. Excellent breakfast." [](https://expedia.co.uk/Sao-Tome-Island-Hotels-Porcelana-Hotel.h31068683.Hotel-Information) ![Hotel Kenito](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/47d5c80e_y.jpg) ### Hotel Kenito 10/10 Excellent "Exceptional" [](https://expedia.co.uk/Sao-Tome-Hotels-Hotel-Kenito.h109258960.Hotel-Information) ## More cheap stays in Guadalupe ![Nour Apartments](https://images.trvl-media.com/lodging/126000000/125770000/125763300/125763221/8fe55824_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Nour Apartments Rua 3 de Fevereiro São Tomé £51 8 Apr - 9 Apr includes taxes & fees [](https://expedia.co.uk/Sao-Tome-Hotels-Nour-Apartments.h125763221.Hotel-Information) ![Hotel Kenito](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/47d5c80e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Kenito Campo de Milho São Tomé £75 21 Apr - 22 Apr includes taxes & fees 10/10 Exceptional! (3 reviews) [](https://expedia.co.uk/Sao-Tome-Hotels-Hotel-Kenito.h109258960.Hotel-Information) ![Sweet Guest House](https://images.trvl-media.com/lodging/13000000/12340000/12336300/12336226/6d211eb5_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Sweet Guest House Vila Dolores n. 087 São Tomé [Get rates](https://expedia.co.uk/Hotel-Search?startDate=17%2F04%2F2026&endDate=18%2F04%2F2026&selected=12336226&PinnedHotelID=12336226&HadPinnedHotel=true®ionId=899031598492831744) [](https://expedia.co.uk/Sao-Tome-Island-Hotels-Sweet-Guest-House.h12336226.Hotel-Information) ![Inviting 10 Bed Apartment in Sao Tome](https://images.trvl-media.com/lodging/96000000/95320000/95318700/95318611/5916db57_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Inviting 10 Bed Apartment in Sao Tome Avenida Marginal 12 de Julho São Tomé São Tomé [Get rates](https://expedia.co.uk/Hotel-Search?startDate=17%2F04%2F2026&endDate=18%2F04%2F2026&selected=95318611&PinnedHotelID=95318611&HadPinnedHotel=true®ionId=899031598492831744) [](https://expedia.co.uk/Sao-Tome-Island-Hotels-Inviting-10-Bed-Apartment-In-Sao-Tome.h95318611.Hotel-Information) ### Pousada Roça São João dos Angolares Cidade dos Angolares São João dos Angolares Sao Tome [Get rates](https://expedia.co.uk/Hotel-Search?startDate=17%2F04%2F2026&endDate=18%2F04%2F2026&selected=46350098&PinnedHotelID=46350098&HadPinnedHotel=true®ionId=899031598492831744) [](https://expedia.co.uk/Sao-Tome-Island-Hotels-Pousada-Roca-Sao-Joao-Dos-Angolares.h46350098.Hotel-Information) ![Monteiro Paradise Guest House](https://images.trvl-media.com/lodging/35000000/34990000/34989100/34989031/7e4d77e4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Monteiro Paradise Guest House 1 Campo de Milho São Tomé [Get rates](https://expedia.co.uk/Hotel-Search?startDate=17%2F04%2F2026&endDate=18%2F04%2F2026&selected=34989031&PinnedHotelID=34989031&HadPinnedHotel=true®ionId=899031598492831744) [](https://expedia.co.uk/Sao-Tome-Island-Hotels-Monteiro-Guest-House.h34989031.Hotel-Information) ## Frequently asked questions ### What is the best area to stay in Guadalupe? > This area is the heart of Guadalupe, with guesthouses and small hotels dotted along the Estrada Litoral. You'll find local shops, a few eateries, and the main public beach within easy reach. It's a relaxed setting, great for experiencing local life without being too isolated. > > > Couples looking for a tranquil retreat will find this area particularly appealing. The proximity to the beach allows for relaxed days by the sea, and the unhurried pace of life is ideal for unwinding. You can enjoy strolls along the coastline and experience the local culture. > > > For those interested in exploring the natural beauty of São Tomé, staying in Guadalupe provides a good base for accessing the northern parts of the island. ### When is the best time to go to Guadalupe? > During these months, you'll experience consistently warm temperatures, generally around 28-30°C, with significantly less rainfall compared to the rest of the year. This makes it ideal for enjoying the island's outdoor activities, such as exploring the beaches, hiking through the plantations, and discovering the local culture without the interruption of heavy downpours. The drier conditions also mean clearer skies for photography and more pleasant evenings for dining al fresco. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Guadalupe hotel booking with Expedia? ### How much is the nightly rate at a Guadalupe hotel? ## Explore a world of travel with Expedia - Accommodation - [Micolo Hotels ](https://www.expedia.co.uk/Micolo-Hotels.d899029226293043200.Travel-Guide-Hotels) - [Santo Amaro Hotels ](https://www.expedia.co.uk/Santo-Amaro-Hotels.d899028466832510976.Travel-Guide-Hotels) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app