Title: Guadalupe Holidays 2026 from £2,247 | Expedia.co.uk [Hotels in Guadalupe](https://expedia.co.uk/Guadalupe-Hotels.d899031598492831744.Travel-Guide-Hotels)[Holiday Rentals in Guadalupe](https://expedia.co.uk/Guadalupe-Holiday-Rentals.d899031598492831744.Travel-Guide-HolidayRentals)[Guadalupe Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Guadalupe.d899031598492831744.Car-Hire-Guide) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Guadalupe Holidays from £2,247 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to £335 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Packages with flights are ATOL protected ## Top Guadalupe Flight + Hotel Deals Price found within the past 48 hours. Click for updated prices. ![Sweet Guest House](https://images.trvl-media.com/lodging/13000000/12340000/12336300/12336226/6d211eb5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Sweet Guest House £2,247 per person 25 Apr - 30 Apr found 14 hours ago Return flight included London (LGW) to São Tomé Island (TMS) 8.8/10 Excellent! (45 reviews) A very clean comfortable good value stay 10 mins walk from the centre of town. There is good WiFi and a laundry and small shop across the road. Reviewed on 27 Jun 2024 ![Alojamento Santos Silva ](https://images.trvl-media.com/lodging/121000000/120460000/120451900/120451805/02be10f5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Alojamento Santos Silva £2,758 per person 25 Apr - 30 Apr found 14 hours ago Return flight included London (LGW) to São Tomé Island (TMS) No reviews ![Pestana São Tomé](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/ea6ea619_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Pestana São Tomé Vila Maria £2,571 per person 25 Apr - 30 Apr found 14 hours ago Return flight included London (LGW) to São Tomé Island (TMS) 8/10 Very Good! (73 reviews) Wonderful stay, great staff, easy, relaxing delightful. Reviewed on 9 Dec 2025 ![Hotel Praia](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/3031ec18_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Praia £2,491 per person 25 Apr - 30 Apr found 14 hours ago Return flight included London (LGW) to São Tomé Island (TMS) 7.6/10 Good! (17 reviews) Pros: Room is very spacious and clean. Common areas also nice and generally I enjoyed a quiet atmosphere. Staff is nice, food is good. Cons: They did not honor the complementary airport transfer that is announced on line, they arranged a private taxi that charged me 20 US Dollars (for a 4 minute ride). The quality of bed linens and towels is not great, they should improve them. The one day I used the pool, which is big and pretty, the water was not clean. Reviewed on 6 Dec 2023 ![Praia Accommodation](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/0767273b_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Praia Accommodation £2,386 per person 25 Apr - 30 Apr found 14 hours ago Return flight included London (LGW) to São Tomé Island (TMS) 7.2/10 Good! (17 reviews) Great place to stay Reviewed on 21 Nov 2024 ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=PKG_SPRING_PROMO_899031598492831744) ## Top hotels in Guadalupe ![Residêncial Tamarindos](https://images.trvl-media.com/lodging/23000000/22710000/22709500/22709437/01e88aa2_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Residêncial Tamarindos Morro Peixe Guadalupe Lobata 8.6/10 Excellent! (14 reviews) This hotel is excellent. My only issue was that someone disconnected the hot water heater and I had to check with the staff before I could get a hot shower. My room had a very good refrigerator and a comfortable bed. Reviewed on 7 Nov 2024 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=03%2F03%2F2026&endDate=04%2F03%2F2026&selected=22709437&PinnedHotelID=22709437&HadPinnedHotel=true®ionId=899031598492831744) [](https://expedia.co.uk/Hotel-Search?startDate=03%2F03%2F2026&endDate=04%2F03%2F2026&selected=22709437&PinnedHotelID=22709437&HadPinnedHotel=true®ionId=899031598492831744) ![Pestana São Tomé](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/ea6ea619_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Pestana São Tomé Avenida Marginal 12 De Julho São Tomé Fully refundableReserve now, pay when you stay £186 20 Feb - 21 Feb includes taxes & fees 8/10 Very Good! (78 reviews) Wonderful stay, great staff, easy, relaxing delightful. Reviewed on 9 Dec 2025 [](https://expedia.co.uk/Hotel-Search?startDate=20%2F02%2F2026&endDate=21%2F02%2F2026&selected=2150447&PinnedHotelID=2150447&HadPinnedHotel=true®ionId=899031598492831744) ![Omali São Tomé – Principe Collection](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/d1688203_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Omali São Tomé – Principe Collection Praia Lagarto São Tomé £173 28 Feb - 1 Mar includes taxes & fees 9.4/10 Exceptional! (62 reviews) Staff was very friendly. Food was excellent. Room was clean and well kept. Reviewed on 4 Dec 2025 [](https://expedia.co.uk/Hotel-Search?startDate=28%2F02%2F2026&endDate=01%2F03%2F2026&selected=6762264&PinnedHotelID=6762264&HadPinnedHotel=true®ionId=899031598492831744) [See all 47 properties in Guadalupe](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=18%2F02%2F2026&endDate=19%2F02%2F2026®ionId=899031598492831744) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holidays](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![Holiday in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app