Find hotels in Santo Antonio from £397

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
21 Feb - 22 Feb
Tomorrow
22 Feb - 23 Feb
Next weekend
27 Feb - 1 Mar
In two weeks
6 Mar - 8 Mar

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santo Antonio hotels

Shower, free toiletries, towels

Residencial Brigada

Residencial Brigada
3.0 star property
Príncipe Island
6.0 out of 10, (2 reviews)
"- Trotz das bei Expedia angegeben wird das Frühstück inkludiert ist, musste hierfür extra bezahlt werden. - Das Hotel ist zur Zeit eine Baustelle, es ist den ganzen Tag über extrem laut. - Im Zimmer gab es mal einen Wasserschaden, diese wurde übergemalt, ist jedoch noch sichtbar und riechbar, wärend man im Zimmer hatte ich ständig ein reizen im Hals und musste husten. - Das Zimmer war sehr ungünstig gelegen, direkt neben der Bar, so das außerhalb der Bauzeiten auch Lärm durch die Bar und Küche...
Germany
Fabian
Residencial Brigada
Coffee shop

Residencial Apresentacao

Residencial Apresentacao
3.5 star property
Príncipe Island
7.2 out of 10, Good, (10 reviews)
"Rito was an amazing host. Super helpful, professional and efficient. Great place to stay"
United Kingdom
Jonathan
Residencial Apresentacao
Breakfast, lunch, dinner served; local and international cuisine

Sundy Praia – Principe Collection

Sundy Praia – Principe Collection
5.0 star property
Príncipe Island
9.6 out of 10, Exceptional, (5 reviews)
"Beautiful boutique property. So private in the rainforest with a beautiful beach where we didn’t see a single person all day. The staff is wonderful and the food was delicious. They do a 3 course meal every night for dinner and a lovely breakfast every morning. The staff’s little surprises throughout our stay made it special, such as filling our tub with flower petals while we were on an excursion or setting up a private breakfast by the beach one morning. "
United States
Jonathan
The price is £817
includes taxes & fees
11 Mar - 12 Mar
Sundy Praia – Principe Collection
Breakfast, lunch, dinner served; local cuisine

Bom Bom – Principe Collection

Bom Bom – Principe Collection
4.0 star property
Príncipe Island
8.4 out of 10, Very good, (7 reviews)
"Outstanding hotel and location, but much too expensive, especially for Sao Tome"
United States
Maurice
The price is £476
includes taxes & fees
24 Feb - 25 Feb
Bom Bom – Principe Collection
Interior

Roça Sundy – Principe Collection

Roça Sundy – Principe Collection
4.0 star property
Príncipe Island
7.8 out of 10, Good, (20 reviews)
"Hotel is located in old plantation. The main house is renoved and designed in colonial style. Room was very big and comfortable, with beautiful tarrace and view. Equipment was great: all you need you can easily find or just ask for this. Staff was extra-nice and very helpful. They are open and smile. You can use their shuttle service to Santo Antonio, Bom Bom Island and airport. Meels was great and tasty. You can eat something from local or continental cuisine. Everything was fresh and...
United States
Miroslaw
The price is £397
includes taxes & fees
14 Mar - 15 Mar
Roça Sundy – Principe Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

The Annual Holiday Sale

Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save.
Book now
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santo Antonio Hotel Reviews

Bom Bom – Principe Collection

Bom Bom – Principe Collection

8/10 Good
"Outstanding hotel and location, but much too expensive, especially for Sao Tome"
Maurice 4-night trip
Posted 2 months ago
Bom Bom – Principe Collection
Residencial Apresentacao

Residencial Apresentacao

8/10 Good
"I had a really nice stay at Residencial Apresentacao. The room was basic, but it was all I needed. Breakfast was good. The owner lived in Manchester for a number of years so he spoke English. A bit of a rarity in Principe. The staff was attentive and friendly. The main street of Santo Antonio was within walking distance which was good. "
James 3-night trip
Posted 11 months ago
Residencial Apresentacao

Frequently asked questions

What is the best area to stay in Santo Antonio?
The best area to stay in Santo António is around the main square, Praça da Independência, which is the heart of the town.

This central area is where you'll find most of the local amenities and is very walkable. The Praça da Independência is surrounded by historic buildings and is a focal point for local life, with the market nearby and the waterfront just a short stroll away. It's a good place to experience the local pace of life.

For travellers seeking convenience and a local experience, staying near the Praça da Independência is ideal.
When is the best time to go to Santo Antonio?
The best time to visit Santo Antonio, Pagué, São Tomé and Príncipe is during the dry season, which runs from June to September.

This period offers pleasant weather with less humidity and sunshine, making it ideal for exploring the island's natural beauty and engaging in outdoor activities. You'll find it more comfortable for hiking through the lush rainforests, visiting cocoa plantations, or simply enjoying the beaches.

Travellers looking for a relaxed beach holiday will find these months particularly appealing. The calmer seas are superb for swimming, snorkelling, and boat trips to nearby islets. It's a great time for couples seeking a tranquil escape with plenty of sunshine.

While the dry season is generally preferred, the shoulder months of May and October also offer good weather with fewer crowds, which can be ideal for those seeking a more secluded experience.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santo Antonio.
How can I save on a Santo Antonio hotel booking with Expedia?
Members always get our best prices. Find our best Santo Antonio hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.
How much is the nightly rate at a Santo Antonio hotel?
Prices for hotels in Santo Antonio often vary, but you can find a great deal from £397 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.