Title: TOP Hotels Suites in Southwest Illinois, IL for 2026 | Expedia.co.uk [Southwest Illinois Travel Guide](https://expedia.co.uk/Southwest-Illinois.dx6058943)[Hotels in Southwest Illinois](https://expedia.co.uk/Southwest-Illinois-Hotels.d6058943.Travel-Guide-Hotels)[Holiday Rentals in Southwest Illinois](https://expedia.co.uk/Southwest-Illinois-Holiday-Rentals.d6058943.Travel-Guide-HolidayRentals)[Flights to Southwest Illinois](https://expedia.co.uk/Cheap-Flights-To-Southwest-Illinois.d6058943.Travel-Guide-Flights)[Southwest Illinois Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southwest-Illinois.d6058943.Car-Hire-Guide)[Southwest Illinois Holidays](https://expedia.co.uk/Southwest-Illinois.d6058943.Holidays-City-Breaks) ![One of the northermost cypress swamps in the States, the Cache River State Natural area is home to Cypress trees that are over 1000 years old. This is shot from the hiking trail (no boat), and was just a sampling of the scores of cypress trees all around. #treetrove](https://images.trvl-media.com/place/553248634983556233/b4c981e9-72cf-4dc0-8b97-270e21fe73c6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Carl Anderson ![](https://images.trvl-media.com/place/553248634983556233/b4c981e9-72cf-4dc0-8b97-270e21fe73c6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southwest Illinois Hotels Suites Tonight [19 Jan - 20 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6058943&startDate=2026-01-19&endDate=2026-01-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [20 Jan - 21 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6058943&startDate=2026-01-20&endDate=2026-01-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6058943&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [30 Jan - 1 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6058943&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Southwest Illinois hotels with suites ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42100/42025/0b9bb173.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/42100/42025/a60abbba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42100/42025/a8315e37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42100/42025/f5a8458f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Marion [](https://www.expedia.co.uk/Carbondale-Hotels-Drury-Inn-Marion.h42025.Hotel-Information) Marion 9.4/10 Exceptional (1,002 reviews) "Clean rooms, great food, friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John £58 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Carbondale-Hotels-Drury-Inn-Marion.h42025.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/798d901b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/31850cab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/24fa28eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/6058a5df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Mt. Vernon [](https://www.expedia.co.uk/Mount-Vernon-Hotels-Drury-Inn-Suites-Mt-Vernon.h42021.Hotel-Information) Mount Vernon 9.6/10 Exceptional (1,629 reviews) "Clean nice people great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John £94 includes taxes & fees 23 Jan - 24 Jan [](https://www.expedia.co.uk/Mount-Vernon-Hotels-Drury-Inn-Suites-Mt-Vernon.h42021.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4980000/4970900/4970883/cbf733c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4980000/4970900/4970883/7e4cb9d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/5000000/4980000/4970900/4970883/95d1b540.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/5000000/4980000/4970900/4970883/7c968655.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Marion Northeast by IHG [](https://www.expedia.co.uk/Carbondale-Hotels-Holiday-Inn-Express-Hotel-Suites-Marion-Northeast.h4970883.Hotel-Information) Marion 9.0/10 Wonderful (937 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles £80 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Carbondale-Hotels-Holiday-Inn-Express-Hotel-Suites-Marion-Northeast.h4970883.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/8000000/7220000/7214300/7214281/1c773b5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/8000000/7220000/7214300/7214281/2700f966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, individually decorated](https://images.trvl-media.com/lodging/8000000/7220000/7214300/7214281/89141360.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, individually decorated](https://images.trvl-media.com/lodging/8000000/7220000/7214300/7214281/83c59bdb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SureStay Hotel by Best Western Whittington Rend Lake [](https://www.expedia.co.uk/Whittington-Hotels-SureStay-Hotel-By-Best-Western-Whittington-Rend-Lake.h7214281.Hotel-Information) Whittington 8.8/10 Excellent (923 reviews) "Great place to stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephen £60 includes taxes & fees 26 Jan - 27 Jan [](https://www.expedia.co.uk/Whittington-Hotels-SureStay-Hotel-By-Best-Western-Whittington-Rend-Lake.h7214281.Hotel-Information) ![Gazebo](https://images.trvl-media.com/lodging/9000000/8080000/8070400/8070312/30c6b3be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8080000/8070400/8070312/0418d6e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout curtains, free cots/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/9000000/8080000/8070400/8070312/594a99d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout curtains, free cots/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/9000000/8080000/8070400/8070312/71b4e886.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Hearth Inn & Suites Edwardsville St. Louis [](https://www.expedia.co.uk/St-Louis-Hotels-Country-Hearth-Inn-Suites-Edwardsville-St-Louis.h8070312.Hotel-Information) Edwardsville 8.6/10 Excellent (657 reviews) "The room was very clean and the staff is always friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lynn £78 includes taxes & fees 4 Feb - 5 Feb [](https://www.expedia.co.uk/St-Louis-Hotels-Country-Hearth-Inn-Suites-Edwardsville-St-Louis.h8070312.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/600/574/40777397.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/600/574/268a0d05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/10000/600/574/1fa6dae3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/600/574/10e308fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Vandalia [](https://www.expedia.co.uk/Carlyle-Lake-Hotels-Ramada-By-Wyndham-Vandalia.h574.Hotel-Information) Vandalia 7.8/10 Good (815 reviews) "Very Clean, big bed. Would stay again, just know you definitely hear the highway all night." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amanda £55 includes taxes & fees 19 Feb - 20 Feb [](https://www.expedia.co.uk/Carlyle-Lake-Hotels-Ramada-By-Wyndham-Vandalia.h574.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/5b15716e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/6732cce6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/cd6d884a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Accessible, Non Smoking | In-room safe, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/b3496784.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Mount Vernon [](https://www.expedia.co.uk/Mount-Vernon-Hotels-Comfort-Suites-Mount-Vernon.h1387309.Hotel-Information) Mount Vernon 9.0/10 Wonderful (1,009 reviews) "It's great for travelers!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kerry £98 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Mount-Vernon-Hotels-Comfort-Suites-Mount-Vernon.h1387309.Hotel-Information) ![Room, 1 Queen Bed, Accessible, Non Smoking | Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/870000/861400/861371/04e0f544.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/870000/861400/861371/cb6402c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/870000/861400/861371/19420497.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/870000/861400/861371/9818af49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Mt. Vernon IL [](https://www.expedia.co.uk/Mount-Vernon-Hotels-Super-8-By-Wyndham-Mt-Vernon-IL.h861371.Hotel-Information) Mount Vernon 7.8/10 Good (1,001 reviews) "Easy check-in. Good rate and dog friendly at a good fee" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Curt £54 includes taxes & fees 22 Jan - 23 Jan [](https://www.expedia.co.uk/Mount-Vernon-Hotels-Super-8-By-Wyndham-Mt-Vernon-IL.h861371.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1320000/1314000/1313908/c32f0b90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Pool Access | Laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1320000/1314000/1313908/84d8b838.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/2000000/1320000/1314000/1313908/4c2c2065.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1320000/1314000/1313908/43c55870.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake [](https://www.expedia.co.uk/Mount-Vernon-Hotels-Fairfield-Inn-Suites-By-Marriott-Mt-Vernon-Rend-Lake.h1313908.Hotel-Information) Mount Vernon 8.8/10 Excellent (688 reviews) "Nice clean and quiet place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas £92 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Mount-Vernon-Hotels-Fairfield-Inn-Suites-By-Marriott-Mt-Vernon-Rend-Lake.h1313908.Hotel-Information) ![In-room safe, desk, iron/ironing board, cots/infant beds](https://images.trvl-media.com/lodging/1000000/180000/171200/171182/71a177b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, cots/infant beds](https://images.trvl-media.com/lodging/1000000/180000/171200/171182/f2c5e9fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/180000/171200/171182/57b5df0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/180000/171200/171182/e0778e13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Vandalia near I-70 and Hwy 51 [](https://www.expedia.co.uk/Carlyle-Lake-Hotels-Quality-Inn-Suites.h171182.Hotel-Information) Vandalia 8.4/10 Very good (1,004 reviews) "Consistently nice place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cindy £51 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Carlyle-Lake-Hotels-Quality-Inn-Suites.h171182.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-03&endDate=2026-02-04®ionId=6058943&adults=2&nearby_group=suites&sort=RECOMMENDED&openPlayBack=true) ## Top Southwest Illinois Hotel Reviews ![Drury Inn & Suites St. Louis O'Fallon, IL](https://images.trvl-media.com/lodging/2000000/1550000/1544100/1544028/d2bc121f_y.jpg) ### Drury Inn & Suites St. Louis O'Fallon, IL 10/10 Excellent "Great place" [](https://expedia.co.uk/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-OFallon.h1544028.Hotel-Information) ![Drury Inn & Suites St. Louis Fairview Heights](https://images.trvl-media.com/lodging/1000000/50000/41900/41802/c56c0460_y.jpg) ### Drury Inn & Suites St. Louis Fairview Heights 10/10 Excellent "Clean room and great amenities!" [](https://expedia.co.uk/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-Fairview-Heights.h41802.Hotel-Information) ![Comfort Suites Mount Vernon](https://images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/b34f836a_y.jpg) ### Comfort Suites Mount Vernon 10/10 Excellent "Yes very clean" [](https://expedia.co.uk/Mount-Vernon-Hotels-Comfort-Suites-Mount-Vernon.h1387309.Hotel-Information) ![Drury Plaza Hotel Mt. Vernon](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/f9296f7b_y.jpg) ### Drury Plaza Hotel Mt. Vernon 10/10 Excellent "Room was very clean, staff is very friendly and the food and drinks amenities were really nice." [](https://expedia.co.uk/Mount-Vernon-Hotels-Drury-Inn-Suites-Mt-Vernon.h42021.Hotel-Information) ## Frequently asked questions ### How much do hotels with suites in Southwest Illinois cost? ### What are the best hotels with suites in Southwest Illinois? ### How many hotels with suites are there in Southwest Illinois? ### What are the best cheap hotels with suites in Southwest Illinois? ### Are there any family-friendly hotels with suites in Southwest Illinois? ### Why book your hotel with suites in Southwest Illinois with Expedia? ### How can I find cheap hotels with suites in Southwest Illinois? ### What is there to do in Southwest Illinois near my hotel with suites? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [4 Star Hotels in Swansea ](https://www.expedia.co.uk/4Star-Swansea-Hotels.s40-0-d164131.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Marissa ](https://www.expedia.co.uk/5Star-Marissa-Hotels.s50-0-d3000434506.Travel-Guide-Filter-Hotels) - 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