A calm lake surrounded by trees and vegetation.

Search Business Hotels in Southwest Illinois

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Check availability on Southwest Illinois Business Hotels

Tonight
17 Oct - 18 Oct
Tomorrow
18 Oct - 19 Oct
Next weekend
23 Oct - 25 Oct
In two weeks
30 Oct - 1 Nov

Our top choices for Southwest Illinois business-friendly hotels

A hotel kitchen with wooden cabinets, a coffee station, and a dining area with tables and chairs.
A reception area with a stone wall, a round mirror, a reception desk, and a computer setup.
A compact kitchenette with a refrigerator and an ice dispenser.
A Best Western U.S. Inn with a modern design, featuring a covered entrance and a parking lot.

1. Best Western U. S. Inn

Best Western U. S. Inn
Nashville
United States
Steven
£98
includes taxes & fees
19 Oct - 20 Oct
Best Western U. S. Inn
A hotel room with two beds, a desk with a computer, a chair, a TV, and two wall-mounted lamps.
A conference room with a TV, a door, and a window with blinds.
A Super 8 motel with a covered entrance, outdoor seating, and a vending machine.
A bathroom with a granite countertop sink, a mirror, a towel rack, and a telephone.

2. Super 8 by Wyndham Okawville

Super 8 by Wyndham Okawville
Okawville
United States
Peter
£52
includes taxes & fees
1 Nov - 2 Nov
Super 8 by Wyndham Okawville
A modern dining area with multiple tables and chairs, a kitchen area with appliances, and a ceiling with recessed lighting and a circular light fixture.
A modern hotel room with a living area, a kitchenette, and a door leading to another room.
A hotel room with a large bed, a desk with a chair, a sofa, and a TV.
A spacious lobby with a modern design, featuring a large seating area with leather chairs, a kitchen area with a counter and appliances, and a flat-screen TV mounted on the wall.

3. Best Western Plus MidAmerica Hotel

Best Western Plus MidAmerica Hotel
Mascoutah
United States
Alice
£86
includes taxes & fees
25 Oct - 26 Oct
Best Western Plus MidAmerica Hotel
A spacious lobby with a stone fireplace, a seating area with a sofa and chairs, and a television mounted on the wall.
A dining area with round tables and chairs, a kitchen with a countertop and appliances, and a hallway leading to another room.
A hotel with a flat facade, multiple windows, and a sign indicating it is a 'SureStay Hotel by Best Western'.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

4. SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
Whittington
United States
Michelle
£71
includes taxes & fees
19 Oct - 20 Oct
SureStay Hotel by Best Western Whittington Rend Lake
A hotel room with a large flat-screen TV, a desk with drawers, a bench, and a wardrobe.
A hot tub area with a view of the parking lot through a glass door.
A compact hotel room with a kitchenette, a blue sofa, a small wooden table, and a wooden floor.
A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.

5. Holiday Inn Express Hotel & Suites Sparta by IHG

Holiday Inn Express Hotel & Suites Sparta by IHG
Sparta
United States
NADINE
£83
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Express Hotel & Suites Sparta by IHG
A restaurant with multiple tables and booths, large windows, and a modern interior design.
A hotel named "The Principal Hotel" with a brick facade, multiple windows, and a parking lot in front.
A modern kitchen with a central island, bar stools, and a dining area.
A wooden wall with the sign "THE PRINCIPAL HOTEL" and a row of books below.

6. The Principal Hotel

The Principal Hotel
Columbia
United States
Jeffrey
£74
includes taxes & fees
1 Nov - 2 Nov
The Principal Hotel
A bar area with a long counter, multiple chairs, and hanging light fixtures.
A hotel lobby with a Kitchen+Bar area, seating arrangements, and a view to the outside.
A hotel room with two beds, a desk with a flat-screen TV, a chair, and a lamp.
A spacious lobby with a reception desk, seating area, and glass doors leading outside.

7. Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
Mount Vernon
United States
Richard
£94
includes taxes & fees
25 Oct - 26 Oct
Drury Plaza Hotel Mt. Vernon
A hotel room with a large bed, a red bedspread, a bathtub, a nightstand with a lamp, and two framed pictures on the wall.
A kitchen with a dishwasher, coffee makers, a water dispenser, and various kitchen utensils.
A hotel room with a bed, a desk with a TV, a chair, a small table, and a couch.
A hotel room with a sofa, two lamps, a television, and a desk.

8. Seasons Inn & Suites Highland

Seasons Inn & Suites Highland
Highland
United States
Jeffrey
£75
includes taxes & fees
19 Oct - 20 Oct
Seasons Inn & Suites Highland
A hotel room with two beds, a desk, a television, and a window with a view of the outdoors.
A hotel room with a bed, a desk, a chair, a TV, a lamp, and a flower arrangement.
A hotel room with two beds, a television, a desk, and a window with curtains.
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

9. Red Bud Country Inn

Red Bud Country Inn
Red Bud
United States
James
£66
includes taxes & fees
19 Oct - 20 Oct
Red Bud Country Inn
A modern spa room with a large hot tub, a glass wall with a reflective pattern, and a ceiling with a skylight.
A hotel lobby with a marble floor, a reception desk, a sign for 'Restrooms', and a large chandelier.
A hotel reception desk with a modern chandelier, a sign indicating 'SPA' coming soon, and two receptionists at their stations.
A hotel lobby with a marble floor, a reception area with a '12 & VINE' sign, and a dining area with orange chairs and chandeliers.

10. Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
Carterville
United States
Ron
£97
includes taxes & fees
27 Oct - 28 Oct
Walker's Bluff Casino Resort
View all properties

Top Southwest Illinois Hotel Reviews

Drury Inn & Suites Marion

Drury Inn & Suites Marion

10/10 Excellent
"Excellent hotel"
Ihab 1-night trip
Posted 6 hours ago
Drury Inn & Suites Marion
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

10/10 Excellent
"We were very satisfied with our stay. Staff was friendly, courteous and helpful. The room was clean and bed and pillows were very comfortable. They had 5:30 enjoy your stay with drinks and food. After checking in, delicious as well as breakfast in the morning. Wonderful stay and will be back."
Santa 1-night trip
Posted 7 hours ago
Drury Inn & Suites St. Louis Fairview Heights
Comfort Suites Mount Vernon

Comfort Suites Mount Vernon

8/10 Good
"Good breakfast and nice staff. Due to having a pet with us we were in a pet room and you could see the damage and smell the smell though the hotel had tried to mitigate the smell. Unfortunate that people don’t care for their pets! One dog was barking and we think it was left in the room alone."
Judi 1-night trip
Posted 10 hours ago
Comfort Suites Mount Vernon
Quality Inn O'Fallon - St. Louis - Shiloh

Quality Inn O'Fallon - St. Louis - Shiloh

8/10 Good
"It was disappointing to not have any protein options for breakfast, and only apples as fruit."
Clara 4-night trip
Posted 2 days ago
Quality Inn O'Fallon - St. Louis - Shiloh
Radisson Hotel Fairview Heights - St. Louis

Radisson Hotel Fairview Heights - St. Louis

10/10 Excellent
"Our hotel stay was absolutely amazing! It was peaceful, relaxing, and honestly one of the best stays we’ve ever had. Everything about the experience made it easy to unwind, enjoy ourselves, and truly relax. Sometimes you just need a little getaway to recharge, and this was exactly that. We left feeling refreshed and happy, and we would absolutely love to stay here again. Highly recommend to anyone looking for a wonderful, relaxing experience! ❤️"
Scott Thompson 3-night trip
Posted 2 days ago
Radisson Hotel Fairview Heights - St. Louis
Best Western Marion Hotel

Best Western Marion Hotel

8/10 Good
"The room was clean and comfortable. Staff was friendly and check in went smoothly. Breakfast was good and coffee is always available. Hotel is being remodeled. Hallways are a mess now. Stay was excellent overall."
David 1-night trip
Posted 4 days ago
Best Western Marion Hotel

Frequently asked questions

How much do business hotels in Southwest Illinois cost?
Business hotels in Southwest Illinois range between £52 and £98 per night. This means you can lock in a property with useful amenities like workspaces and conference rooms at a price that fits your budget. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business hotels are there in Southwest Illinois?
When your next work trip takes you around Southwest Illinois, you'll have 105 business hotels to pick from.
Why book your business hotel in Southwest Illinois with Expedia?
Here at Expedia, our job is to help you land the ideal stay at the right price. From luxurious, corporate-friendly retreats to affordable motels filled with handy amenities, you'll have your next work trip planned in a few quick clicks.
How can I find cheap business hotels in Southwest Illinois?
Expedia can help you narrow your search for cheap business hotels in Southwest Illinois. Simply head to the "traveller experience" filter and click on "business friendly." This will show you stays with amenities designed to help you work productively and comfortably, like included breakfast and free WiFi. You can also choose your budget and preferred star rating to keep costs under control.

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