A calm lake surrounded by trees and vegetation.

Search Business Hotels in Southwest Illinois

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Check availability on Southwest Illinois Business Hotels

Tonight
29 Sept - 30 Sept
Tomorrow
30 Sept - 1 Oct
This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Our top choices for Southwest Illinois business-friendly hotels

A hotel kitchen with wooden cabinets, a coffee station, and a dining area with tables and chairs.
A hotel room with two beds, a desk, and a window with a view.
A reception area with a stone wall, a round mirror, a reception desk, and a computer setup.
A compact kitchenette with a refrigerator and an ice dispenser.

1. Best Western U. S. Inn

Best Western U. S. Inn
Nashville
United States
Arilla
£99
includes taxes & fees
30 Sept - 1 Oct
Best Western U. S. Inn
A hotel room with two beds, a desk with a computer, a chair, a TV, and two wall-mounted lamps.
A bathroom with a granite countertop sink, a mirror, a towel rack, and a telephone.
A reception area with a counter, framed certificates, a clock, and a checkered floor.
A Super 8 motel with a covered entrance, outdoor seating, and a vending machine.

2. Super 8 by Wyndham Okawville

Super 8 by Wyndham Okawville
Okawville
United States
Peter
£52
includes taxes & fees
19 Oct - 20 Oct
Super 8 by Wyndham Okawville
A hotel room with a large flat-screen TV, a desk with drawers, a bench, and a wardrobe.
A patio area with outdoor seating, including chairs and tables, and a covered area with umbrellas.
A hot tub area with a view of the parking lot through a glass door.
A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.

3. Holiday Inn Express Hotel & Suites Sparta by IHG

Holiday Inn Express Hotel & Suites Sparta by IHG
Sparta
United States
Jeremy
£88
includes taxes & fees
4 Oct - 5 Oct
Holiday Inn Express Hotel & Suites Sparta by IHG
A modern dining area with multiple tables and chairs, a kitchen area with appliances, and a ceiling with recessed lighting and a circular light fixture.
A spacious lobby with a stone reception desk, leather seating, and a large window offering a view of the outdoors.
A modern hotel room with a living area, a kitchenette, and a door leading to another room.
A hotel room with a large bed, a desk with a chair, a sofa, and a TV.

4. Best Western Plus MidAmerica Hotel

Best Western Plus MidAmerica Hotel
Mascoutah
United States
Danny
£94
includes taxes & fees
4 Oct - 5 Oct
Best Western Plus MidAmerica Hotel
A bar area with a long counter, multiple chairs, and hanging light fixtures.
An indoor swimming pool with a metal ladder, a warning sign about cold weather, and a view of the outside.
A hotel room with two beds, a desk with a flat-screen TV, a chair, and a lamp.
A spacious lobby with a reception desk, seating area, and glass doors leading outside.

5. Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
Mount Vernon
United States
Kirstyn
£94
includes taxes & fees
4 Oct - 5 Oct
Drury Plaza Hotel Mt. Vernon
A hotel room with a large bed, a red bedspread, a bathtub, a nightstand with a lamp, and two framed pictures on the wall.
A hotel room with a wooden dining table, four brown chairs, a beige sofa, a small wooden coffee table, a lamp, a framed picture on the wall, and a kitchenette with a microwave.
A hotel room with a bed, a desk with a TV, a chair, a small table, and a couch.
A hotel room with a sofa, two lamps, a television, and a desk.

6. Seasons Inn & Suites Highland

Seasons Inn & Suites Highland
Highland
United States
Jeffrey
£75
includes taxes & fees
4 Oct - 5 Oct
Seasons Inn & Suites Highland
A modern spa room with a large hot tub, a glass wall with a reflective pattern, and a ceiling with a skylight.
A hotel lobby with a marble floor, a reception area with a '12 & VINE' sign, and a dining area with orange chairs and chandeliers.
A casino interior with slot machines, a large chandelier, and a carpeted floor.
A hotel lobby with a marble floor, a reception desk, a sign for 'Restrooms', and a large chandelier.

7. Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
Carterville
United States
Kyle
£119
includes taxes & fees
21 Oct - 22 Oct
Walker's Bluff Casino Resort
A spacious lobby with a stone fireplace, a seating area with a sofa and chairs, and a television mounted on the wall.
A dining area with round tables and chairs, a kitchen with a countertop and appliances, and a hallway leading to another room.
A hallway with vending machines and a carpeted floor.
A hotel with a flat facade, multiple windows, and a sign indicating it is a 'SureStay Hotel by Best Western'.

8. SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
Whittington
United States
MARK
£68
includes taxes & fees
6 Oct - 7 Oct
SureStay Hotel by Best Western Whittington Rend Lake
An outdoor patio with stone fire pit, colorful striped sofas, and blue chairs.
A hotel reception area with a wooden reception desk, a digital kiosk, and a refrigerated display case with beverages.
A hotel with a covered entrance, outdoor seating, and a flag.
A spacious lobby with a central seating area, a large window, and a reception desk.

9. Home2 Suites by Hilton Carbondale

Home2 Suites by Hilton Carbondale
Carbondale
United States
Alyssa
£103
includes taxes & fees
27 Oct - 28 Oct
Home2 Suites by Hilton Carbondale
A hotel room with two beds, a desk, a television, and a window with a view of the outdoors.
A Country Inn Motel sign, a parking lot, and a building with an American flag.
A hotel room with a bed, a desk, a chair, a TV, a lamp, and a flower arrangement.
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

10. Red Bud Country Inn

Red Bud Country Inn
Red Bud
United States
Richard
£66
includes taxes & fees
16 Oct - 17 Oct
Red Bud Country Inn
View all properties

Top Southwest Illinois Hotel Reviews

Drury Inn & Suites St. Louis Collinsville

Drury Inn & Suites St. Louis Collinsville

10/10 Excellent
"Staff was great, evening drinks and snacks are wonderful Breakfast was good with good selection"
Heather 1-night trip
Posted 5 hours ago
Drury Inn & Suites St. Louis Collinsville
Comfort Suites Mount Vernon

Comfort Suites Mount Vernon

8/10 Good
"Finally a room with a walk in shower and grab bars by toilet"
Anjanette 1-night trip
Posted 6 hours ago
Comfort Suites Mount Vernon
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent
"Fabulous that I arrived & had Happy Hour Meal with Drinks & a great breakfast! Thx! Dennis D."
Dennis 1-night trip
Posted 19 hours ago
Drury Inn & Suites St. Louis O'Fallon, IL
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

8/10 Good
"It was a quick only one night stop for us during our cross-country trip. It was okay, I say it is definitely budget friendly. Shower power was weak. Clean and comfortable for us! It was close enough driving distance to visit Gateway arch National Park in MO."
Mikiko 1-night trip
Posted 1 day ago
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
Baymont by Wyndham Marion

Baymont by Wyndham Marion

8/10 Good
"The only thing that I think would be good to change is to add something so the bath tubs are not so slippery."
Deb 3-night trip
Posted 2 days ago
Baymont by Wyndham Marion
Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis

10/10 Excellent
"Property was well maintained. The room was clean and the bed was comfortable. The shower looked a little worn in some spots but it was fine overall. Room was cool and you could control the temperature. The breakfast was great and a nice touch every morning. Food was fresh and hot. Staff was friendly. We came for family weekend and we would stay again."
Veronica 3-night trip
Posted 2 days ago
Comfort Inn Edwardsville - St. Louis
Radisson Hotel Fairview Heights - St. Louis

Radisson Hotel Fairview Heights - St. Louis

8/10 Good
"Our stay at the Radisson was good overall and the prices are good . The location was convenient to restaurants and shopping .The first room had a wet carpet smell and the front desk was notified and immediately moved us to another room . The bed was comfortable, the bar inside was nice and reasonably priced. The property was clean and everyone was friendly . My only complaint would be our towels had stains on them and the room had minor spots and stains in certain areas but overall the stay was nice and we would definitely stay again ."
Kaiya 2-night trip
Posted 2 days ago
Radisson Hotel Fairview Heights - St. Louis
Country Inn & Suites by Radisson, Fairview Heights, IL

Country Inn & Suites by Radisson, Fairview Heights, IL

10/10 Excellent
"Was perfect for our plans. Hotel was clean with friendly staff."
Markel 1-night trip
Posted 8 days ago
Country Inn & Suites by Radisson, Fairview Heights, IL

Frequently asked questions

How much do business hotels in Southwest Illinois cost?
Business hotels in Southwest Illinois range between £52 and £117 per night. This means you can lock in a property with useful amenities like workspaces and conference rooms at a price that fits your budget. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business hotels are there in Southwest Illinois?
When your next work trip takes you around Southwest Illinois, you'll have 105 business hotels to pick from.
Why book your business hotel in Southwest Illinois with Expedia?
Here at Expedia, our job is to help you land the ideal stay at the right price. From luxurious, corporate-friendly retreats to affordable motels filled with handy amenities, you'll have your next work trip planned in a few quick clicks.
How can I find cheap business hotels in Southwest Illinois?
Expedia can help you narrow your search for cheap business hotels in Southwest Illinois. Simply head to the "traveller experience" filter and click on "business friendly." This will show you stays with amenities designed to help you work productively and comfortably, like included breakfast and free WiFi. You can also choose your budget and preferred star rating to keep costs under control.

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