A calm lake surrounded by trees and vegetation.

Search Business Hotels in Southwest Illinois

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Check availability on Southwest Illinois Business Hotels

Tonight
6 Oct - 7 Oct
Tomorrow
7 Oct - 8 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for Southwest Illinois business-friendly hotels

A hotel kitchen with wooden cabinets, a coffee station, and a dining area with tables and chairs.
A hotel room with two beds, a desk, and a window with a view.
A Best Western U.S. Inn with a modern design, featuring a covered entrance and a parking lot.
A compact kitchenette with a refrigerator and an ice dispenser.

1. Best Western U. S. Inn

Best Western U. S. Inn
Nashville
United States
Steven
£99
includes taxes & fees
12 Oct - 13 Oct
Best Western U. S. Inn
A hotel room with two beds, a desk with a computer, a chair, a TV, and two wall-mounted lamps.
A bathroom with a granite countertop sink, a mirror, a towel rack, and a telephone.
A Super 8 motel with a covered entrance, outdoor seating, and a vending machine.
A conference room with a TV, a door, and a window with blinds.

2. Super 8 by Wyndham Okawville

Super 8 by Wyndham Okawville
Okawville
United States
Peter
£49
includes taxes & fees
12 Oct - 13 Oct
Super 8 by Wyndham Okawville
A modern dining area with multiple tables and chairs, a kitchen area with appliances, and a ceiling with recessed lighting and a circular light fixture.
A spacious lobby with a stone reception desk, leather seating, and a large window offering a view of the outdoors.
A spacious lobby with a modern design, featuring a large seating area with leather chairs, a kitchen area with a counter and appliances, and a flat-screen TV mounted on the wall.
A modern hotel room with a living area, a kitchenette, and a door leading to another room.

3. Best Western Plus MidAmerica Hotel

Best Western Plus MidAmerica Hotel
Mascoutah
United States
Danny
£91
includes taxes & fees
12 Oct - 13 Oct
Best Western Plus MidAmerica Hotel
A spacious lobby with a stone fireplace, a seating area with a sofa and chairs, and a television mounted on the wall.
A hallway with vending machines and a carpeted floor.
A dining area with round tables and chairs, a kitchen with a countertop and appliances, and a hallway leading to another room.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

4. SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
Whittington
United States
MARK
£72
includes taxes & fees
7 Oct - 8 Oct
SureStay Hotel by Best Western Whittington Rend Lake
A bar area with a long counter, multiple chairs, and hanging light fixtures.
A hotel room with two beds, a desk with a flat-screen TV, a chair, and a lamp.
A spacious lobby with a reception desk, seating area, and glass doors leading outside.
An indoor swimming pool with a metal ladder, a warning sign about cold weather, and a view of the outside.

5. Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
Mount Vernon
United States
Susan
£95
includes taxes & fees
11 Oct - 12 Oct
Drury Plaza Hotel Mt. Vernon
A hotel room with a large flat-screen TV, a desk with drawers, a bench, and a wardrobe.
A compact hotel room with a kitchenette, a blue sofa, a small wooden table, and a wooden floor.
A hot tub area with a view of the parking lot through a glass door.
A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.

6. Holiday Inn Express Hotel & Suites Sparta by IHG

Holiday Inn Express Hotel & Suites Sparta by IHG
Sparta
United States
Jeremy
£84
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Express Hotel & Suites Sparta by IHG
A restaurant with multiple tables and booths, large windows, and a modern interior design.
A hotel named "The Principal Hotel" with a brick facade, multiple windows, and a parking lot in front.
A wooden wall with the sign "THE PRINCIPAL HOTEL" and a row of books below.
A modern kitchen with a central island, bar stools, and a dining area.

7. The Principal Hotel

The Principal Hotel
Columbia
United States
Kenny
£76
includes taxes & fees
26 Oct - 27 Oct
The Principal Hotel
A modern spa room with a large hot tub, a glass wall with a reflective pattern, and a ceiling with a skylight.
A casino interior with slot machines, a large chandelier, and a carpeted floor.
A hotel lobby with a marble floor, a reception desk, a sign for 'Restrooms', and a large chandelier.
A hotel lobby with a marble floor, a reception area with a '12 & VINE' sign, and a dining area with orange chairs and chandeliers.

8. Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
Carterville
United States
Michael
£99
includes taxes & fees
12 Oct - 13 Oct
Walker's Bluff Casino Resort
A hotel room with two beds, a desk, a television, and a window with a view of the outdoors.
A hotel room with a bed, a desk, a chair, a TV, a lamp, and a flower arrangement.
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.
A hotel room with two beds, a television, a desk, and a window with curtains.

9. Red Bud Country Inn

Red Bud Country Inn
Red Bud
United States
Richard
£66
includes taxes & fees
16 Oct - 17 Oct
Red Bud Country Inn
A hotel room with a large bed, a red bedspread, a bathtub, a nightstand with a lamp, and two framed pictures on the wall.
A hotel room with a wooden dining table, four brown chairs, a beige sofa, a small wooden coffee table, a lamp, a framed picture on the wall, and a kitchenette with a microwave.
A kitchen with a dishwasher, coffee makers, a water dispenser, and various kitchen utensils.
A hotel room with a bed, a desk with a TV, a chair, a small table, and a couch.

10. Seasons Inn & Suites Highland

Seasons Inn & Suites Highland
Highland
United States
Jeffrey
£75
includes taxes & fees
11 Oct - 12 Oct
Seasons Inn & Suites Highland
View all properties

Top Southwest Illinois Hotel Reviews

Drury Inn & Suites Marion

Drury Inn & Suites Marion

8/10 Good
"friendly and helpful staff. Great food with many options to choose from. Great hot tub"
Carolyn 1-night trip
Posted 18 hours ago
Drury Inn & Suites Marion
Radisson Hotel Fairview Heights - St. Louis

Radisson Hotel Fairview Heights - St. Louis

8/10 Good
"Parking was easy room was clean.water pressure was low .you have to pay for breakfast. Over all I would stay again."
Teresa 3-night trip
Posted 1 day ago
Radisson Hotel Fairview Heights - St. Louis
Drury Inn & Suites St. Louis Collinsville

Drury Inn & Suites St. Louis Collinsville

10/10 Excellent
"Great place to stay - clean, great staff and breakfast was really good."
Yvonne 1-night trip
Posted 2 days ago
Drury Inn & Suites St. Louis Collinsville
Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis

10/10 Excellent
"Nice location."
James 4-night trip
Posted 2 days ago
Comfort Inn Edwardsville - St. Louis
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent
"Great staff and clean room"
Aaron 1-night trip
Posted 4 days ago
Drury Inn & Suites St. Louis O'Fallon, IL
Best Western St. Louis Fairview Heights

Best Western St. Louis Fairview Heights

8/10 Good
"Hotel is remodeling for a fresh new look Rooms were nice. Hot breakfast. Close to restaurants and shopping."
Christina 1-night trip
Posted 9 days ago
Best Western St. Louis Fairview Heights
Country Inn & Suites by Radisson, Marion, IL

Country Inn & Suites by Radisson, Marion, IL

10/10 Excellent
"This is an excellent hotel to stay at. Updated, easy parking, staff is very friendly, breakfast is great, will stay at this hotel again."
Lisa 3-night trip
Posted 9 days ago
Country Inn & Suites by Radisson, Marion, IL

Frequently asked questions

How much do business hotels in Southwest Illinois cost?
Business hotels in Southwest Illinois range between £49 and £99 per night. This means you can lock in a property with useful amenities like workspaces and conference rooms at a price that fits your budget. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business hotels are there in Southwest Illinois?
When your next work trip takes you around Southwest Illinois, you'll have 105 business hotels to pick from.
Why book your business hotel in Southwest Illinois with Expedia?
Here at Expedia, our job is to help you land the ideal stay at the right price. From luxurious, corporate-friendly retreats to affordable motels filled with handy amenities, you'll have your next work trip planned in a few quick clicks.
How can I find cheap business hotels in Southwest Illinois?
Expedia can help you narrow your search for cheap business hotels in Southwest Illinois. Simply head to the "traveller experience" filter and click on "business friendly." This will show you stays with amenities designed to help you work productively and comfortably, like included breakfast and free WiFi. You can also choose your budget and preferred star rating to keep costs under control.

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