Title: TOP Business Hotels in Southwest Florida, FL for 2026 | Expedia.co.uk [Southwest Florida Travel Guide](https://expedia.co.uk/Southwest-Florida.dx6233839)[Hotels in Southwest Florida](https://expedia.co.uk/Southwest-Florida-Hotels.d6233839.Travel-Guide-Hotels)[Holiday Rentals in Southwest Florida](https://expedia.co.uk/Southwest-Florida-Holiday-Rentals.d6233839.Travel-Guide-HolidayRentals)[Flights to Southwest Florida](https://expedia.co.uk/Cheap-Flights-To-Southwest-Florida.d6233839.Travel-Guide-Flights)[Things to do in Southwest Florida](https://expedia.co.uk/Things-To-Do-In-Southwest-Florida.d6233839.Travel-Guide-Activities)[Southwest Florida Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southwest-Florida.d6233839.Car-Hire-Guide)[Southwest Florida Holidays](https://expedia.co.uk/Southwest-Florida.d6233839.Holidays-City-Breaks) ![Delnor-Wiggins Pass State Park showing a beach as well as a couple](https://images.trvl-media.com/place/6065875/bc23d051-1ceb-4c43-a754-b9feb3316d59.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Business Hotels in Southwest Florida - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southwest Florida Business Hotels Tonight [6 Jan - 7 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6233839&startDate=2026-01-06&endDate=2026-01-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [7 Jan - 8 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6233839&startDate=2026-01-07&endDate=2026-01-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [9 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6233839&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6233839&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Southwest Florida business-friendly hotels ![Property entrance](https://images.trvl-media.com/lodging/23000000/22500000/22492300/22492255/de6b5b90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/23000000/22500000/22492300/22492255/d3615161.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/23000000/22500000/22492300/22492255/d96dd9cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/23000000/22500000/22492300/22492255/3ed2496c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Punta Gorda by IHG [](https://www.expedia.co.uk/Port-Charlotte-Charlotte-Harbor-Hotels-Holiday-Inn-Express-And-Suites-Punta-Gorda.h22492255.Hotel-Information) Punta Gorda 9.4/10 Exceptional (1007) "Clean room, good location, reasonable price." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John £91 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Port-Charlotte-Charlotte-Harbor-Hotels-Holiday-Inn-Express-And-Suites-Punta-Gorda.h22492255.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/120000/117100/117009/bbaa2af7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/117100/117009/d81d6192.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/120000/117100/117009/01ed8c5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/120000/117100/117009/2279042b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Ambassador Suites Venice [](https://www.expedia.co.uk/Sarasota-Hotels-Best-Western-Plus-Ambassador-Suites-Venice.h117009.Hotel-Information) Venice 9.0/10 Wonderful (1000) "The room was spotless and the staff were terrific." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lorraine £113 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Sarasota-Hotels-Best-Western-Plus-Ambassador-Suites-Venice.h117009.Hotel-Information) ![On the beach, sun-loungers, beach towels](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/f97bdde8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, sun-loungers, beach towels](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/6b3a0fb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/aa9b23b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Balcony (Gulf View) | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/f85ea0c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sanibel Island Beach Resort [](https://www.expedia.co.uk/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) Mid Island 9.2/10 Wonderful (1516) "Great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Philip £204 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292808/19e6461a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292808/32ad5c82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, Multiple Beds, Non Smoking | Premium bedding, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292808/be0ae601.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292808/61f4ca47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Port Charlotte, FL [](https://www.expedia.co.uk/Port-Charlotte-Charlotte-Harbor-Hotels-Country-Inn-Suites-By-Radisson.h2292808.Hotel-Information) Port Charlotte 7.8/10 Good (1195) "I felt safe and comfortable as a solo traveler here over Christmas. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melissa £69 includes taxes & fees 14 Jan - 15 Jan [](https://www.expedia.co.uk/Port-Charlotte-Charlotte-Harbor-Hotels-Country-Inn-Suites-By-Radisson.h2292808.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2210000/2202400/2202318/eaa3eb69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2210000/2202400/2202318/be6c8e7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/3000000/2210000/2202400/2202318/7facc2d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2210000/2202400/2202318/f1596925.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites [](https://www.expedia.co.uk/Port-Charlotte-Charlotte-Harbor-Hotels-Comfort-Inn-Suites.h2202318.Hotel-Information) Port Charlotte 8.4/10 Very good (1015) "Room was clean, staff was very attentive." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joyce £70 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Port-Charlotte-Charlotte-Harbor-Hotels-Comfort-Inn-Suites.h2202318.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/800000/798500/798422/46330a76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/800000/798500/798422/1fa522a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/800000/798500/798422/a840448a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Premium bedding, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/800000/798500/798422/d3248701.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park [](https://www.expedia.co.uk/Fort-Myers-Hotels-Days-Inn-Suites-By-Wyndham-Fort-Myers-Near-JetBlue-Park.h798422.Hotel-Information) Daniels Corridor 8.0/10 Very good (1535) "Loved the stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Moosa Nazar £69 includes taxes & fees 7 Jan - 8 Jan [](https://www.expedia.co.uk/Fort-Myers-Hotels-Days-Inn-Suites-By-Wyndham-Fort-Myers-Near-JetBlue-Park.h798422.Hotel-Information) ![Lounge](https://images.trvl-media.com/lodging/1000000/30000/21400/21331/6dc32504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/21400/21331/125fc79b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas](https://images.trvl-media.com/lodging/1000000/30000/21400/21331/0817b12f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21400/21331/d6e8eb4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Golden Host Resort - Sarasota [](https://www.expedia.co.uk/Sarasota-Hotels-Golden-Host-Resort-Sarasota.h21331.Hotel-Information) North Trail 8.4/10 Very good (2194) "Great Place To Stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pete £65 includes taxes & fees 7 Jan - 8 Jan [](https://www.expedia.co.uk/Sarasota-Hotels-Golden-Host-Resort-Sarasota.h21331.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/5000000/4520000/4513100/4513051/9c00e0a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/5000000/4520000/4513100/4513051/b80b1ff5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4520000/4513100/4513051/ea10bb34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4520000/4513100/4513051/7fb404a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Punta Gorda/Port Charlotte [](https://www.expedia.co.uk/Port-Charlotte-Charlotte-Harbor-Hotels-Baymont-By-Wyndham-Punta-GordaPort-Charlotte.h4513051.Hotel-Information) Punta Gorda 8.4/10 Very good (1159) "Friendly staff, good breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tom £74 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Port-Charlotte-Charlotte-Harbor-Hotels-Baymont-By-Wyndham-Punta-GordaPort-Charlotte.h4513051.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40900/40858/7d170878.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch, dinner served; American cuisine, pool views ](https://images.trvl-media.com/lodging/1000000/50000/40900/40858/d3c9515d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40900/40858/bb6d486e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch, dinner served; American cuisine, pool views ](https://images.trvl-media.com/lodging/1000000/50000/40900/40858/4088f841.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Trianon Bonita Bay [](https://www.expedia.co.uk/Naples-Hotels-Trianon-Bonita-Bay.h40858.Hotel-Information) Bonita Bay 9.2/10 Wonderful (1727) "Clean and comfy rooms and staff was great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jarrett £107 includes taxes & fees 14 Jan - 15 Jan [](https://www.expedia.co.uk/Naples-Hotels-Trianon-Bonita-Bay.h40858.Hotel-Information) ![Food and drink](https://images.trvl-media.com/lodging/3000000/2200000/2193300/2193202/75be6006.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/3000000/2200000/2193300/2193202/dd6b01a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges](https://images.trvl-media.com/lodging/3000000/2200000/2193300/2193202/c82c9425.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2200000/2193300/2193202/26b62c9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyvern Hotel, an Ascend Collection Hotel [](https://www.expedia.co.uk/Port-Charlotte-Charlotte-Harbor-Hotels-Wyvern-Hotel.h2193202.Hotel-Information) Downtown Punta Gorda 8.8/10 Excellent (1006) "Great breakfast menu and beautiful rooms!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lucas £132 includes taxes & fees 7 Jan - 8 Jan [](https://www.expedia.co.uk/Port-Charlotte-Charlotte-Harbor-Hotels-Wyvern-Hotel.h2193202.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-20&endDate=2026-01-21®ionId=6233839&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Southwest Florida Hotel Reviews ![Hyatt Place Sarasota/Bradenton Airport](https://images.trvl-media.com/lodging/3000000/2280000/2277500/2277489/6e9ac4ec_y.jpg) ### Hyatt Place Sarasota/Bradenton Airport 10/10 Excellent "The inside of the hotel looked like it was recently remodeled as everything looked new. The staff was friendly and helpful. I was pleased with the experience of staying there." [](https://expedia.co.uk/Sarasota-Hotels-Hyatt-Place-SarasotaBradenton-Airport.h2277489.Hotel-Information) ![Naples Grande Beach Resort](https://images.trvl-media.com/lodging/1000000/20000/15900/15898/65da812e_y.jpg) ### Naples Grande Beach Resort 10/10 Excellent "Room was very nice. Really appreciated the grown-ups only pool. Beach was a short golf cart drive away. Menu was accessible for my entire family." [](https://expedia.co.uk/Naples-Hotels-Naples-Grande-Beach-Resort.h15898.Hotel-Information) ![Golden Host Resort - Sarasota](https://images.trvl-media.com/lodging/1000000/30000/21400/21331/125fc79b_y.jpg) ### Golden Host Resort - Sarasota 10/10 Excellent "Super great!! clean, great price, nice place, safe... I will back soon again! " [](https://expedia.co.uk/Sarasota-Hotels-Golden-Host-Resort-Sarasota.h21331.Hotel-Information) ![DiamondHead Beach Resort](https://images.trvl-media.com/lodging/1000000/210000/200700/200632/814c4388_y.jpg) ### DiamondHead Beach Resort 10/10 Excellent "Great room and facilities. Loved the location!!" [](https://expedia.co.uk/Fort-Myers-Hotels-DiamondHead-Beach-Resort.h200632.Hotel-Information) ![Hilton Marco Island Beach Resort and Spa](https://images.trvl-media.com/lodging/1000000/20000/17600/17575/65dd4041_y.jpg) ### Hilton Marco Island Beach Resort and Spa 10/10 Excellent "Great rooms, love the beach, pool nice but does not get sun until late afternoon " [](https://expedia.co.uk/Naples-Hotels-Hilton-Marco-Island-Beach-Resort.h17575.Hotel-Information) ![Fairways Inn of Naples](https://images.trvl-media.com/lodging/1000000/60000/55500/55415/9ba98d99_y.jpg) ### Fairways Inn of Naples 10/10 Excellent "This gem property is the highlight of our year; we gift ourselves a stay every Christmas and it never disappoints!" [](https://expedia.co.uk/Naples-Hotels-Fairways-Inn-Of-Naples.h55415.Hotel-Information) ![Lani Kai Beachfront Resort](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/b5b17142_y.jpg) ### Lani Kai Beachfront Resort 10/10 Excellent "Rooms were very clean. It was amazing to have the beach within footsteps. Rooftop bar had a great bartender and drinks " [](https://expedia.co.uk/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) ![Holiday Inn Express Cape Coral-Fort Myers Area by IHG](https://images.trvl-media.com/lodging/1000000/30000/26900/26860/ab39b98c_y.jpg) ### Holiday Inn Express Cape Coral-Fort Myers Area by IHG 10/10 Excellent "Clean room good breakfast " [](https://expedia.co.uk/Fort-Myers-Hotels-Holiday-Inn-Express-Cape-Coral-Fort-Myers-Area.h26860.Hotel-Information) ![Sanibel Island Beach Resort](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/w2247h1500x326y0-2ea06bb5_y.jpg) ### Sanibel Island Beach Resort 10/10 Excellent "We had 2 rooms both of which were great. The were very clean and comfortable. The hotel was cute and right on the beach with a pool an" [](https://expedia.co.uk/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) ## Frequently asked questions ### How much do business hotels in Southwest Florida cost? ### How many business hotels are there in Southwest Florida? ### Why book your business hotel in Southwest Florida with Expedia? ### How can I find cheap business hotels in Southwest Florida? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Other - More ways to book - [Gay-Friendly Hotels in Audubon ](https://www.expedia.co.uk/Audubon-Naples-Hotels-Gay-Friendly-Hotel.0-n553248635976469139-0-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Adults Only Resorts & in Bonita Springs ](https://www.expedia.co.uk/Bonita-Springs-Hotels-Adults-Only-Resorts.0-0-d6403-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Beach Resorts & in Bonita Springs ](https://www.expedia.co.uk/Bonita-Springs-Hotels-Beach-Hotels.0-0-d6403-tBeachHotels.Travel-Guide-Filter-Hotels) - 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