Title: TOP Southeastern Indiana Spa Hotels for 2025 - Spas in Southeastern Indiana | Expedia.co.uk [Southeastern Indiana Travel Guide](https://expedia.co.uk/Southeastern-Indiana.dx6233889)[Hotels in Southeastern Indiana](https://expedia.co.uk/Southeastern-Indiana-Hotels.d6233889.Travel-Guide-Hotels)[Holiday Rentals in Southeastern Indiana](https://expedia.co.uk/Southeastern-Indiana-Holiday-Rentals.d6233889.Travel-Guide-HolidayRentals)[Flights to Southeastern Indiana](https://expedia.co.uk/Cheap-Flights-To-Southeastern-Indiana.d6233889.Travel-Guide-Flights)[Southeastern Indiana Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southeastern-Indiana.d6233889.Car-Hire-Guide)[Southeastern Indiana Holidays](https://expedia.co.uk/Southeastern-Indiana.d6233889.Holidays-City-Breaks) ![Louisville showing street scenes and signage as well as a small group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/297000/297251-Louisville-And-Vicinity.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Southeastern Indiana ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southeastern Indiana Spa Hotels Tonight [12 Oct - 13 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6233889&startDate=2025-10-12&endDate=2025-10-13&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [13 Oct - 14 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6233889&startDate=2025-10-13&endDate=2025-10-14&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6233889&startDate=2025-10-17&endDate=2025-10-19&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [24 Oct - 26 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6233889&startDate=2025-10-24&endDate=2025-10-26&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Southeastern Indiana Spa Hotels ![4 restaurants, breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/594caae3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/23521baa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/9c82234b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Galt House Hotel Trademark Collection by Wyndham Downtown Louisville 9.0/10 Wonderful (3672) "Th Galt House is a beautiful place to stay. " £122 includes taxes & fees 30 Oct - 31 Oct [](https://www.expedia.co.uk/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/04047b8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 9:00 AM to 9:00 PM, pool cabanas (surcharge)](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/18d76505.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/029a183a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, down duvets, in-room safe](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/b866fa6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Belterra Casino Resort Florence 8.6/10 Excellent (1009) "Nice property, staff and rooms. Would definitely stay here again. " £137 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/Madison-Hotels-Belterra-Casino-Resort.h1152807.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/a9b7038a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/864ff441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/22b7d23e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/cef338e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 21c Museum Hotel Louisville Downtown Louisville 9.4/10 Exceptional (1004) "Great stay overall. " £146 includes taxes & fees 9 Nov - 10 Nov [](https://www.expedia.co.uk/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/80fbdedc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/54f0e03a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/a36c57b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/2339d325.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Caesars Southern Indiana - A Caesars Rewards Destination Elizabeth 8.2/10 Very good (1009) "Beautiful property. Perfect stay " £89 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/Elizabeth-Hotels-Caesars-Southern-Indiana.h795844.Hotel-Information) ![Sauna, body treatments, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/4c7c479b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/e108d0ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast served](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/w5757h3840x3y0-b0a2f211.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, cocktail bar, lobby lounge](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/547de83e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omni Louisville Hotel Downtown Louisville 9.2/10 Wonderful (1641) "Great stay" £175 includes taxes & fees 25 Oct - 26 Oct [](https://www.expedia.co.uk/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/49600/49545/a62748ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast ](https://images.trvl-media.com/lodging/1000000/50000/49600/49545/d9aa7346.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/50000/49600/49545/5eb0602d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/49600/49545/8952f069.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Seymour I-65 Seymour 7.0/10 Good (536) "For the price this is an excellent hotel." £68 includes taxes & fees 10 Nov - 11 Nov [](https://www.expedia.co.uk/Columbus-Hotels-Quality-Inn-Seymour-I-65.h49545.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/9cc68008.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/f227b8bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Apartment, Multiple Beds, Kitchenette, Garden View | Living area | 42-inch flat-screen TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/3fd39b2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Apartment, 1 King Bed with Sofa bed, Kitchenette, Garden View | Terrace/patio](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/46f16aa2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pillow and Paddock B&B La Grange 10/10 Exceptional (50) "This has been our second time staying here and we will continue to come back. Beautiful home, amazing breakfasts, and wonderful hosts, not much else we could ask for. " [](https://www.expedia.co.uk/Louisville-Hotels-Pillow-And-Paddock-BB.h11688222.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-26&endDate=2025-10-27®ionId=6233889&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Southeastern Indiana Hotel Reviews ![Hampton Inn New Albany Louisville West](//images.trvl-media.com/lodging/1000000/30000/25400/25301/eb53eba8_y.jpg) ### Hampton Inn New Albany Louisville West 10/10 Excellent "Rooms were clean and comfortable. Staff members were very nice and helpful. 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