Title: TOP Southeast Minnesota Spa Hotels for 2026 - Spas in Southeast Minnesota, MN | Expedia.co.uk [Southeast Minnesota Travel Guide](https://expedia.co.uk/Southeast-Minnesota.dx6233996)[Hotels in Southeast Minnesota](https://expedia.co.uk/Southeast-Minnesota-Hotels.d6233996.Travel-Guide-Hotels)[Holiday Rentals in Southeast Minnesota](https://expedia.co.uk/Southeast-Minnesota-Holiday-Rentals.d6233996.Travel-Guide-HolidayRentals)[Flights to Southeast Minnesota](https://expedia.co.uk/Cheap-Flights-To-Southeast-Minnesota.d6233996.Travel-Guide-Flights)[Southeast Minnesota Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southeast-Minnesota.d6233996.Car-Hire-Guide)[Southeast Minnesota Holidays](https://expedia.co.uk/Southeast-Minnesota.d6233996.Holidays-City-Breaks) ![The Mississippi River near Hannibal, Missouri, USA](https://images.trvl-media.com/place/6209928/2afb9a4b-494b-462a-af23-159cb6a96bb2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Southeast Minnesota, MN - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southeast Minnesota Spa Hotels Tonight [11 Jan - 12 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6233996&startDate=2026-01-11&endDate=2026-01-12&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [12 Jan - 13 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6233996&startDate=2026-01-12&endDate=2026-01-13&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6233996&startDate=2026-01-16&endDate=2026-01-18&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6233996&startDate=2026-01-23&endDate=2026-01-25&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Southeast Minnesota hotels with a spa ![Body treatments, hot stone massages, deep-tissue massages](https://images.trvl-media.com/lodging/105000000/104470000/104463200/104463121/4b090314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/105000000/104470000/104463200/104463121/d285c34e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104470000/104463200/104463121/21f7d30f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, pool cabanas (surcharge), pool loungers](https://images.trvl-media.com/lodging/105000000/104470000/104463200/104463121/c875c14c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Treasure Island Resort & Casino [](https://www.expedia.co.uk/Welch-Hotels-Treasure-Island-Resort-And-Casino.h104463121.Hotel-Information) Welch 8.0/10 Very good (31 reviews) "Loved the hotel would love to stay again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David £78 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Welch-Hotels-Treasure-Island-Resort-And-Casino.h104463121.Hotel-Information) ![Presidential Suite, Multiple Beds | Living area | 55-inch LCD TV with satellite channels, TV](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/c7a0b093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/b1555778.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/86063f91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch LCD TV with satellite channels, TV](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/ef0f8d85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Rochester Mayo Clinic Area [](https://www.expedia.co.uk/Rochester-Hotels-Hilton-Rochester-Mayo-Clinic-Area.h27426319.Hotel-Information) Downtown Rochester 9.6/10 Exceptional (552 reviews) "Very courteous staff, loved the valet guy!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jean £147 includes taxes & fees 17 Jan - 18 Jan [](https://www.expedia.co.uk/Rochester-Hotels-Hilton-Rochester-Mayo-Clinic-Area.h27426319.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/8900/8820/dabc1b97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/8900/8820/9dfd099b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite Riverside | Premium bedding, in-room safe, individually decorated, desk](https://images.trvl-media.com/lodging/1000000/10000/8900/8820/4f82f8a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cocktail bar](https://images.trvl-media.com/lodging/1000000/10000/8900/8820/40306b49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### St James Hotel, a Historic Hotel of America [](https://www.expedia.co.uk/Red-Wing-Hotels-St-James-Hotel.h8820.Hotel-Information) Red Wing 9.2/10 Wonderful (1,006 reviews) "Absolutely beautiful, historical, quiet. Friendly staff. Our stay was memorable and amazing!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ruth £116 includes taxes & fees 13 Jan - 14 Jan [](https://www.expedia.co.uk/Red-Wing-Hotels-St-James-Hotel.h8820.Hotel-Information) ![Serves lunch, dinner and happy hour](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/96cfed25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/4090d22a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Patio Room, 1 King Bed, Pet-Friendly, Non Smoking | Premium bedding, down duvets, pillow-top beds, desk](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/079e9789.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Rochester Near Mayo Clinic [](https://www.expedia.co.uk/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) Rochester 8.0/10 Very good (1,172 reviews) "Room clean, staff nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Terry £66 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/16000000/15300000/15291300/15291258/98f05f5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/16000000/15300000/15291300/15291258/f1422307.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/16000000/15300000/15291300/15291258/8b47f98d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds (Non-Accessible) | Premium bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/16000000/15300000/15291300/15291258/d538e557.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grandstay Hotel and Suites [](https://www.expedia.co.uk/Owatonna-Hotels-Grandstay-Hotel-And-Suites.h15291258.Hotel-Information) Waseca 7.6/10 Good (247 reviews) "Very clean and nice staff. The room itself was a little out of date with new paint and things like that. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Samantha £70 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Owatonna-Hotels-Grandstay-Hotel-And-Suites.h15291258.Hotel-Information) ![Porch](https://images.trvl-media.com/lodging/47000000/46990000/46980900/46980893/d54840be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/47000000/46990000/46980900/46980893/e1720891.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/47000000/46990000/46980900/46980893/df1235ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/47000000/46990000/46980900/46980893/455654ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Round Barn Farm B & B Event Center [](https://www.expedia.co.uk/Red-Wing-Hotels-Round-Barn-Farm-B-B-Event-Center.h46980893.Hotel-Information) Red Wing 10/10 Exceptional (40 reviews) "Beautiful property with great hosts! Strongly recommend!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Austin [](https://www.expedia.co.uk/Red-Wing-Hotels-Round-Barn-Farm-B-B-Event-Center.h46980893.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/200000/199000/198946/61e51f32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/200000/199000/198946/0fb5698e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 restaurants, breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/200000/199000/198946/673d14c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/1000000/200000/199000/198946/ae960123.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mystic Lake Casino Hotel [](https://www.expedia.co.uk/Minneapolis-St-Paul-Hotels-Mystic-Lake-Casino-Hotel.h198946.Hotel-Information) Prior Lake 9.0/10 Wonderful (2,390 reviews) "Second time here room and pool/hot tub were great !!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Louis £90 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Minneapolis-St-Paul-Hotels-Mystic-Lake-Casino-Hotel.h198946.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/55000000/54180000/54172300/54172209/d500dbb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/55000000/54180000/54172300/54172209/b65aee43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dinner served](https://images.trvl-media.com/lodging/55000000/54180000/54172300/54172209/06ffc248.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, in-room safe, desk](https://images.trvl-media.com/lodging/55000000/54180000/54172300/54172209/90f9b86d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omni Viking Lakes Hotel [](https://www.expedia.co.uk/Minneapolis-St-Paul-Hotels-Omni-Viking-Lakes-Hotel.h54172209.Hotel-Information) Eagan 9.6/10 Exceptional (1,001 reviews) "Great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John £129 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Minneapolis-St-Paul-Hotels-Omni-Viking-Lakes-Hotel.h54172209.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-26&endDate=2026-01-27®ionId=6233996&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Southeast Minnesota ### Top Southeast Minnesota attractions for a relaxing vacation Southeast Minnesota is a hidden gem for travellers seeking rejuvenation and relaxation, particularly those inclined to indulge in hotels with spas. Begin your journey in Rochester, renowned for the prestigious Mayo Clinic, where you can enjoy a luxurious spa experience followed by a stroll through the serene landscapes of Quarry Hill Nature Center, featuring picturesque trails and native wildlife. Just a short drive away, the charming town of Lanesboro offers a unique blend of art and nature; consider renting a bike to explore the scenic Root River State Trail, or unwind at a local spa that incorporates natural elements into its treatments. The historic district of Winona showcases beautiful architecture and an array of boutique shops, perfect for a leisurely afternoon, and the nearby Garvin Heights Vineyards provides wine tasting with breathtaking views of the Mississippi River. For an ideal stay, consider hotels in the heart of Rochester, where you’ll find top spas and attentive service, allowing you to unwind in style after a day of exploration. With its welcoming atmosphere and array of wellness activities, Southeast Minnesota promises a refreshing escape that caters to your every need. ## Top Southeast Minnesota Hotel Reviews ![Spark by Hilton Rochester South](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3_y.jpg) ### Spark by Hilton Rochester South 10/10 Excellent "Clean, quiet and a spacious room at a reasonable price." [](https://expedia.co.uk/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![Kahler Inn and Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/e56e7dae_y.jpg) ### Kahler Inn and Suites - Mayo Clinic Area 10/10 Excellent "We enjoy staying at Kahler Inn & Suites. So nice to be so close to Mayo Clinic. You don't have to go outside. You can walk from the hotel tp Mayo. Everyone is so friendly and the breakfast is great!" [](https://expedia.co.uk/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) ![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg) ### Kahler Grand Hotel 10/10 Excellent "No free breakfast " [](https://expedia.co.uk/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Hotel Indigo Rochester – Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010_y.jpg) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG 10/10 Excellent "Clean room and friendly staff! Great breakfast at restaurant as well!" [](https://expedia.co.uk/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) ![St James Hotel, a Historic Hotel of America](https://images.trvl-media.com/lodging/1000000/10000/8900/8820/c90b9231_y.jpg) ### St James Hotel, a Historic Hotel of America 10/10 Excellent "We checked in on Christmas Day 2025 and stayed 1 night. The hotel is in the heart of beautiful downtown Red Wing, MN. The hotel was beautifully decorated for the holidays and was warm and inviting. We had brunch at the beautiful Scarlet Kitchen and Bar and the food and service could not have been better. The restaurant was busy, yet the vibe was elegantly relaxed. Our room was a beautiful union of history in modern times. The beautiful 4-post bed was so comfortable and I need to know where I can get a set of those bed sheets! So buttery soft—best night’s sleep! I will be back St. James Hotel. Highly recommend. Beautiful and quaint shops and dining on-site and within walking distance in Red Wing. Beautiful and historic." [](https://expedia.co.uk/Red-Wing-Hotels-St-James-Hotel.h8820.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353_y.jpg) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S 10/10 Excellent "Friendly staff and very clean " [](https://expedia.co.uk/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![Aspen Suites](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/6c7e0658_y.jpg) ### Aspen Suites 10/10 Excellent "Clean room" [](https://expedia.co.uk/Rochester-Hotels-Aspen-Suites.h904615.Hotel-Information) ![AmericInn by Wyndham Rochester Near Mayo Clinic](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30_y.jpg) ### AmericInn by Wyndham Rochester Near Mayo Clinic 10/10 Excellent "Check in was fast, room, and pool area were great, its connected to the crooked pint, making dining convenient. " [](https://expedia.co.uk/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![Holiday Inn Express Rochester South - Mayo Area by IHG](https://images.trvl-media.com/lodging/3000000/2190000/2185000/2184971/62a372dd_y.jpg) ### Holiday Inn Express Rochester South - Mayo Area by IHG 10/10 Excellent "Clean room, clean hotel, friendly staff Would stay here again." 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