Entire home

Serenity South -- Gardens, River-Views, and Refreshing Space

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Dining - Serenity South -- Gardens, River-Views, and Refreshing Space (Cape Girardeau)
Terrace/patio - Serenity South -- Gardens, River-Views, and Refreshing Space (Cape Girardeau)
Interior - Serenity South -- Gardens, River-Views, and Refreshing Space (Cape Girardeau)
TV, fireplace, DVD player, books - Serenity South -- Gardens, River-Views, and Refreshing Space (Cape Girardeau)
Fridge, microwave, oven, stovetop - Serenity South -- Gardens, River-Views, and Refreshing Space (Cape Girardeau)
In the heart of Cape Girardeau Historic District, this beautifully renovated duplex offers a cozy living room and large dining room perfect for relaxation. Explore downtown's local restaurants, antique shops, and boutiques within walking distance or unwind on the balcony overlooking the shared yard.

Reviews

10 out of 10
Exceptional

Entire home

3 bedrooms2 bathroomsSleeps 51600 sq ft

Popular amenities

  • Kitchen
  • Outdoor space
  • Parking available
  • Fireplace
The current price is £186
includes taxes & fees
1 Apr - 2 Apr

Add dates for prices

About this property

Entire place

You'll have the entire home to yourself and will only share it with other guests in your party.

Serenity South -- Gardens, River-Views, and Refreshing Space

Beautifully renovated duplex with large shared yard in Cape Girardeau Historic District. Cozy living room, large dining room, fully stocked kitchen, 3 second-story bedrooms with balcony at the end of the hall, and 1 1/2 bathes. Perfect for getting away for rejuvenation or exploring downtown. Within walking distance to local downtown restaurants, antique shops, and boutiques. Two blocks from the Mississippi River and many other attractions.

Property amenities

Internet

  • Available in the house: WiFi

Parking and transport

  • Car not required
  • Parking on site

Kitchen

  • Coffee grinder
  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dishwasher
  • Hob
  • Ice maker
  • Microwave
  • Oven
  • Paper towels
  • Refrigerator
  • Spices
  • Toaster

Bedrooms

  • 3 bedrooms
  • Bedsheets provided

Bathroom

  • 1.5 bathrooms
  • Bathtub or shower
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Living spaces

  • Fireplace
  • Living room
  • Separate dining area

Entertainment

  • Books
  • DVD player
  • Games
  • TV

Outdoor areas

  • Balcony
  • Garden
  • Outdoor furniture

Laundry

  • Laundromat nearby

Comfort

  • Air conditioning
  • Heating

Pets

  • No pets allowed

Suitability/Accessibility

  • Smoke-free property

Services and conveniences

  • Iron/ironing board

Location highlights

  • Near a health/beauty spa
  • Near a hospital
  • Near an outlet shopping centre
  • On a river

Things to do

  • Basketball nearby
  • Casino nearby
  • Cycling nearby
  • Fishing nearby
  • Golfing nearby
  • Hiking/biking trails nearby
  • Horseback riding nearby
  • Motor boating nearby
  • Swimming nearby
  • Wildlife walks nearby
  • Winery tours nearby

Safety features

  • Carbon monoxide detector (host has indicated there is a carbon monoxide detector on the property)
  • Smoke detector (host has indicated there is a smoke detector on the property)
  • Deadbolt lock

General

  • Garden
  • Unit size: 1,600 square feet

Similar properties

Policies

Check-in

Check-in time starts at 4:00 PM
Minimum check-in age - 18

Check-out

Check-out before 11:00 AM

Special check-in instructions

You will receive an email from the host with check-in and check-out instructions
Information provided by the property may be translated using automated translation tools

Rules

Back yard is shared with the other side of the duplex. Please respect their use of the common space.

Pets

Pets not allowed

Children and extra beds

Children are welcome
Note from host: Excellent fenced back yard.

Events

Events allowed: family gatherings, birthday parties, weddings
Parties or events must okayed before arrival.

Smoking

Smoking is not permitted

Important information

You need to know

This property is managed by a professional host. The provision of housing is linked to their trade, business or profession.
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
Parties and events (including family gatherings, birthday parties and weddings) are allowed on site. Maximum attendees: 50
Note from host: Parties or events must okayed before arrival.
Host has indicated that there is a carbon monoxide detector on the property
Host has indicated that there is a smoke detector on the property
Safety features at this property include a deadlock
This property is managed through our partner, Vrbo. You will receive an email from Vrbo with a link to a Vrbo account, where you can change or cancel your reservation
If you cancel your booking, you'll be subject to the host's cancellation policy. In accordance with UK consumer law, property booking services are not subject to the right of withdrawal.

We should mention

A car is not required for transport to and from this property

About the area

Located in Cape Girardeau, this holiday home is near a water park and on a river. The area's natural beauty can be seen at Shawnee National Forest and Mississippi River. Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center are also worth visiting. Discover the area's water adventures with power boating and fishing nearby, or enjoy the great outdoors with cycling and horse riding. Visit our Cape Girardeau travel guide
View more Holiday homes in Cape Girardeau
Map
Cape Girardeau, MO

What's nearby

  • View of the Christopher S. Bond Bridge over Missouri River in Kansas City, from the riverfront park
    Riverfront Bridge Park
    5 min walk - 0.3 miles
  • Panorama of Academic Hall, Southeast Missouri State University
    Southeast Missouri State University
    2 min drive - 1.1 miles
  • eDen Spa & Salon
    2 min walk - 0.1 miles
  • Riverfront Park
    2 min walk - 0.1 miles
  • Century Casino & Hotel Cape Girardeau
    19 min walk - 1.0 mile

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    12 min drive

Restaurants

  • Sand's Pancake House
    11 min walk
  • Hamburger Express
    16 min walk
  • Roni’s Mac Bar
    16 min walk
  • Katy O'Ferrell's Publick House
    9 min walk
  • Minglewood Brewery
    7 min walk

Frequently asked questions

Is Serenity South -- Gardens, River-Views, and Refreshing Space pet-friendly?

No, pets are not allowed at this property.

How much does it cost to stay at Serenity South -- Gardens, River-Views, and Refreshing Space?

As of 29 Mar 2026, prices found for a 1-night stay for 2 adults at Serenity South -- Gardens, River-Views, and Refreshing Space on 1 Apr 2026 start from £186, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

How much is parking at Serenity South -- Gardens, River-Views, and Refreshing Space?

On-site parking is available at the property.

What time is check-in at Serenity South -- Gardens, River-Views, and Refreshing Space?

Check-in begins at 4:00 PM.

What time is check-out at Serenity South -- Gardens, River-Views, and Refreshing Space?

Checkout is at 11:00 AM.

Where is Serenity South -- Gardens, River-Views, and Refreshing Space located?

Situated on a river, this holiday home is steps away from eDen Spa & Salon, Shawnee National Forest and Mississippi River. Riverfront Park and The Glenn House are also within 5 minutes.

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Serenity South -- Gardens, River-Views, and Refreshing Space Reviews

Reviews

Exceptional

All reviews shown are from real guest experiences. Only travellers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.
More informationOpens in a new window
Rating 10 - Excellent. 147 out of 152 reviews
Rating 8 - Good. 5 out of 152 reviews
Rating 6 - Okay. 0 out of 152 reviews
Rating 4 - Poor. 0 out of 152 reviews
Rating 2 - Terrible. 0 out of 152 reviews

10

Cleanliness

9.8

Location

10

Property conditions & facilities

Reviews

Verified

8/10 Good

Tamy R.

Liked: Cleanliness, check-in, communication, listing accuracy
Host was fantastic. House is just like the pictures.
Stayed 2 nights in Dec 2025
Verified

10/10 Excellent

Alison C.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Wonderful location! WonderfulStay
Stayed 1 night in Nov 2025
Verified

8/10 Good

Michael W.

Liked: Cleanliness, check-in, communication
All was good except for the strange fact of 3 rentals at the same place and the older couple in the backyard was a little off putting.
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

Isaac S.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Home was very tidy, kitchen was spacious, and bedrooms comfortable.
Stayed 2 nights in Oct 2025
Verified

10/10 Excellent

Michael R.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Nice property near downtown in the river. This was the perfect location for our 50th high school reunion.
Stayed 2 nights in Oct 2025
Verified

10/10 Excellent

Shelley L.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Good stay.
Stayed 1 night in Sep 2025
Verified

10/10 Excellent

Sandy M.

Liked: Cleanliness, check-in, communication, location, listing accuracy
We were visiting our daughter who attends SEMO, so the location was perfect.
Stayed 3 nights in Sep 2025
Verified

10/10 Excellent

Deborah K.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Charming house within walking distance to downtown restaurants and bars. Host is wonderful! Great communication.
Stayed 1 night in Sep 2025
Verified

10/10 Excellent

Donna D.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Lovely as always

Moving our daughter in to the dorm at SEMO for yr 2. Been coming to this location since our trip here during her senior year of HS when she visited SEMO to audition for the musical theatre program. It is a great place to stay when you have more than 2 people.
Stayed 1 night in Aug 2025
Verified

10/10 Excellent

Tracy H.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Such a great place and location
Stayed 2 nights in Jul 2025
Verified

10/10 Excellent

Jodie F.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Enjoyed everything! Great location!
Stayed 4 nights in Jul 2025
Verified

10/10 Excellent

Nichole C.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Serenity south was welcoming comfortable and very clean. Impeccably maintained historic home. Comfortable beds, great water pressure and shower head, easy to maintain consistent temperature. Good vibes throughout. Not haunted. Beautiful outdoor space but it was too hot to use it much while we were there. Recommend stopping by the olive oil store William and Water across the street.
Stayed 3 nights in Jul 2025
Verified

10/10 Excellent

Bryan P.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Comfortable & Clean

Great Location short walking distance to the Downtown Area with lots do do, Restaurants, Water Park, Shopping. This is the 2nd time I have stayed and it is a true delight. Very spacious and comfortable. Easy to communicate with the Owner/Manager. I will be staying there again in the future. I recommend it with 5 Stars!
Stayed 1 night in Jun 2025
Verified

10/10 Excellent

Vicki R.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Beautiful house. Great stay. Would definitely stay again!
Stayed 1 night in Jun 2025
Verified

10/10 Excellent

Linden S.

Liked: Cleanliness, check-in, communication, location, listing accuracy

A Beautiful Retreat for Three Generations

Three generations found rest,beauty,& joy at Serenity South. Thoughtful touches,beautiful gardens and Cape charm made this more than a stay-it became a treasured memory. We were so appreciative of the details, the fresh flowers, homemade cookies, the coffeemaker upstairs and the books and games. The beds were all comfortable. We enjoyed this historical home and our stay.
Stayed 2 nights in May 2025
Verified

10/10 Excellent

STEPHANIE L.

Liked: Cleanliness, check-in, communication, location, listing accuracy

In town for one day

Its was different, but over all it was on point.I will rebook this summer
Stayed 1 night in May 2025
Verified

10/10 Excellent

Sam E.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Downtown home with great character

My son and two brothers stayed a night in this lovely home. I travel to Cape frequently to visit my son and will definitely stay here again.
Stayed 1 night in Apr 2025
Verified

10/10 Excellent

Michelle K.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Perfect home for college visit

When looking for a VRBO for our daughter's college visit, we knew the perfect place to stay! This is our second stay at Serenity South and it was just as incredible as the first visit. Clean, inviting and cozy. Thanks Jo for another beautiful stay.
Stayed 1 night in Feb 2025
Verified

10/10 Excellent

Penny F.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Beautiful getaway!

The property was exactly as listed with so many little touches that made it special. Communication was great and we were close to downtown shops and the casino. We will definitely stay again when we are in the area.
Stayed 2 nights in Mar 2025
Verified

10/10 Excellent

Rhonda S.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Smith Women’s Weekend

We had a wonderful time at Serenity South! The house is quiet and very clean, in walking distance of fantastic shops and fun places to eat. We look forward to returning next year!
Stayed 2 nights in Feb 2025
Verified

10/10 Excellent

shirley g.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Outstanding

Here for a volleyball tournament. Had 3 short days to enjoy this beautiful home. Just not long enough. Has everything u need and more. Jo is a lovely host. So quiet and peaceful.. most of all in a safe area. I plan to go back by summers end just so I can enjoy the home and walk to coffee shop and tour the old part of town. Just wonderful!
Stayed 3 nights in Feb 2025
Verified

10/10 Excellent

Jennifer K.

Liked: Cleanliness, check-in, communication, location, listing accuracy

This property is excellent

This is an older home (1920’s?) with so much charm. It’s exceptionally well cared for - the floors are clean and in excellent condition, the walls are clean, paint job is beautiful, etc. The air is clean (no smell of mold) bathroom fans work, etc! In short, one of the best maintained rentals we’ve stayed in. The beds are comfy. Oh - and the landscaping is also beautiful! It is winter - would love to see the gardens in the spring. Jo was easy to contact, check in was easy. The trains do run 1 or 2 times per night and are close and on Friday night there were some people having fun running their loud cars through town but otherwise it is quiet and peaceful. The walk to town is only a few blocks. We would definitely stay here again!
Stayed 4 nights in Dec 2024
Verified

10/10 Excellent

Michelle A B.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Great stay!

This was the second year in a row that we have stayed here. This is a beautiful home to stay in. I love the charm and detail of the house. We stay here after a Christmas party and walk downtown so it’s definitely located in a convenient spot. I will be booking again for next year Great communication with Jo and if there’s any questions I need, Jo is very quick to respond. Thank you for making our stay good!
Stayed 1 night in Dec 2024
Verified

10/10 Excellent

Steve B.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Excellent choice

Very nice property. Highly recommend.
Stayed 2 nights in Oct 2024
Verified

10/10 Excellent

joe R.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Cape Girardeau

Beautiful very clean house with a lot of character
Stayed 1 night in Oct 2024