A calm body of water, a sandy beach, and a forested area in the distance.

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Our top choices for Cape Girardeau holiday homes

1. Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very good, (59 reviews)
"Great cute place. "
United States
Jeremy W.
The price is £69
includes taxes & fees
18 Nov - 19 Nov
Little Blue Cottage on Spanish

2. Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals

Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals
Cape Girardeau
The price is £141
includes taxes & fees
7 Dec - 8 Dec
Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals

3. Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly

Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly
Cape Girardeau
10.0 out of 10, Exceptional, (3 reviews)
"The house was very clean and Will kept and the whole property was well maintained. It was very comfortable and nicely decorated. The host was very responsive and helpful! Would definitely stay again and recommend."
United States
Sara C.
The price is £164
includes taxes & fees
19 Nov - 20 Nov
Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly

4. The Little Château | Woodland Escape

The Little Château | Woodland Escape
Cape Girardeau
The price is £166
includes taxes & fees
23 Nov - 24 Nov
The Little Château | Woodland Escape

5. The Little Cape Lofted Cottage | Creek & Nature

The Little Cape Lofted Cottage | Creek & Nature
Cape Girardeau
9.0 out of 10, Wonderful, (2 reviews)
"It was very clean and had a good feel. It was well stocked. I appreciated the cute little ice tray in the freezer that was full. I also appreciated 4 waters in the fridge. The bed on the loft upstairs was atrocious. You can feel the springs through the mattress. The downstairs bed was good. The pillows were fantastic! I’m a pillow snob. We needed a quick place to land for a church function so I can’t say much about the outside amenities as we weren’t there much. But it was a beautifully tucked...
United States
Trisha S.
The price is £171
includes taxes & fees
23 Nov - 24 Nov
The Little Cape Lofted Cottage | Creek & Nature

6. 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.8 out of 10, Excellent, (46 reviews)
"Will definitely book again! Great location, comfortable stay."
United States
Pynktoria !.
The price is £226
includes taxes & fees
15 Nov - 16 Nov
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

7. Beautifully Renovated Farmhouse in Jackson, MO

Beautifully Renovated Farmhouse in Jackson, MO
Jackson
9.4 out of 10, Exceptional, (3 reviews)
" great stay,property landscape nicely manicured, quiet and relaxing inside and outside of the the dwelling."
United States
Sandy S.
The price is £215
includes taxes & fees
16 Nov - 17 Nov
Beautifully Renovated Farmhouse in Jackson, MO

8. 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Cape Girardeau
9.8 out of 10, Exceptional, (11 reviews)
"Nice place, great times"
United States
Jace W.
The price is £415
includes taxes & fees
15 Nov - 16 Nov
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

9. Cozy and Updated Farmhouse with King Suite

Cozy and Updated Farmhouse with King Suite
Anna
10.0 out of 10, Exceptional, (30 reviews)
"Comfortable bed which is what we needed. We weren’t there long but is was everything we needed."
United States
Kathy H.
The price is £125
includes taxes & fees
24 Nov - 25 Nov
Cozy and Updated Farmhouse with King Suite

10. The Weber Farm - Enjoy a beautiful 100 acre farm!

The Weber Farm - Enjoy a beautiful 100 acre farm!
Frohna
10.0 out of 10, Exceptional, (34 reviews)
"Wonderful time! "
United States
Alison C.
The price is £151
includes taxes & fees
1 Dec - 2 Dec
The Weber Farm - Enjoy a beautiful 100 acre farm!

11. Peach Tree Inn, downtown Cobden

Peach Tree Inn, downtown Cobden
Cobden
10.0 out of 10, Exceptional, (3 reviews)
"Amazing place to stay. Excellent location, beautiful rooms and accommodation and the host was so responsive. We will definitely be back!"
United States
Rebecca L.
The price is £170
includes taxes & fees
16 Nov - 17 Nov
Peach Tree Inn, downtown Cobden

12. Stunning 2 bedroom in town, close to Shawnee National Forest

Stunning 2 bedroom in town, close to Shawnee National Forest
Jonesboro
10.0 out of 10, Exceptional, (15 reviews)
"The place was nice and clean and the hosts were great. Would definitely stay there again!"
United States
Katlynn R.
The price is £208
includes taxes & fees
24 Nov - 25 Nov
Stunning 2 bedroom in town, close to Shawnee National Forest

13. Pa’s House is an enjoyable, entirely remodeled, 2-bedroom farmhouse near Anna.

Pa’s House is an enjoyable, entirely remodeled, 2-bedroom farmhouse near Anna.
Anna
10.0 out of 10, Exceptional, (16 reviews)
"We enjoyed our stay here. The beds were very comfortable and it was close to all of the wineries along the wine trail."
United States
Kristi H.
The price is £194
includes taxes & fees
16 Nov - 17 Nov
Pa’s House is an enjoyable, entirely remodeled, 2-bedroom farmhouse near Anna.

14. Peaceful, Comfy and Pet Friendly 2-bedroom home in Quiet Makanda

Peaceful, Comfy and Pet Friendly 2-bedroom home in Quiet Makanda
Makanda
10.0 out of 10, Exceptional, (1 review)
"Awesome stay! We recommend!"
United States
Debrasues M.
The price is £97
includes taxes & fees
25 Nov - 26 Nov
Peaceful, Comfy and Pet Friendly 2-bedroom home in Quiet Makanda

15. Beautiful location in the secluded woods

Beautiful location in the secluded woods
Pomona
9.8 out of 10, Exceptional, (86 reviews)
"This rental was very clean, pet friendly, and definitely secluded. We enjoyed our stay here."
United States
Candi M.
The price is £127
includes taxes & fees
1 Dec - 2 Dec
Beautiful location in the secluded woods

16. Magical Victorian near hiking / wine trail

Magical Victorian near hiking / wine trail
Anna
10.0 out of 10, Exceptional, (21 reviews)
"Everything was beautiful, and although we weren’t there for a long time, enjoyed an Incredible sleep in the most comfortable beds!"
United States
Rachel H.
The price is £248
includes taxes & fees
15 Nov - 16 Nov
Magical Victorian near hiking / wine trail

17. Walk to Weddings-Wineries-Trails, Family Friendly Home in Downtown Alto Pass

Walk to Weddings-Wineries-Trails, Family Friendly Home in Downtown Alto Pass
Alto Pass
10.0 out of 10, Exceptional, (5 reviews)
"The house was very welcoming and clean. Very inviting for our short stay. "
United States
brian O.
The price is £191
includes taxes & fees
24 Nov - 25 Nov
Walk to Weddings-Wineries-Trails, Family Friendly Home in Downtown Alto Pass

18. Farm Fresh Eggs, Golf Cart, Telescope

Farm Fresh Eggs, Golf Cart, Telescope
Alto Pass
9.8 out of 10, Exceptional, (16 reviews)
"It’s a very cute old farm house nestled in a peach orchard! Rolling hills with a porch swing that overlooks the orchards and a pond. The hosts provide all of the essential's for a comfortable stay! Communication is wonderful from beginning to the end! Would stay here again and again!"
United States
Gary A.
The price is £193
includes taxes & fees
16 Nov - 17 Nov
Farm Fresh Eggs, Golf Cart, Telescope

19. King Suite, Hot Tub, walk to Iron Whisk

King Suite, Hot Tub, walk to Iron Whisk
Cobden
10.0 out of 10, Exceptional, (1 review)
"Loved my stay here! The attention to details is appreciated. The shower is amazing! Loved the main area for all to gather. Walking distance to The Iron Whisk and Fuzzy’s Bar is great. I didn’t love that it’s close to train tracks and that you can’t adjust your own thermostat."
United States
Christy
The price is £170
includes taxes & fees
16 Nov - 17 Nov
King Suite, Hot Tub, walk to Iron Whisk

20. King Suite, Hot Tubs, Cobden

King Suite, Hot Tubs, Cobden
Cobden
10.0 out of 10, Exceptional, (1 review)
"Everything was clean and new! We used the hot tub every night and appreciated the coffee machine! Really classy place! Access to attractions was key, and we enjoyed the neighboring restaurant (only open Thurs-Sunday) but we were less than 10 minutes from Anna for dining, and there was a great Tavern and gas station, and Dollar General less than a 1/4 block away. Highly recommended."
United States
Keith M.
The price is £170
includes taxes & fees
16 Nov - 17 Nov
King Suite, Hot Tubs, Cobden
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cape Girardeau Hotel Reviews

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Cape Girardeau Holiday Homes information

Number of reviews
214
Accommodation
77 Holiday Homes
Lowest Price
£69
Highest Price
£415