A calm body of water, a sandy beach, and a forested area in the distance.

Search Holiday Homes in Cape Girardeau

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
28 Aug - 30 Aug
In two months
9 Oct - 11 Oct
In three months
6 Nov - 8 Nov
In four months
4 Dec - 6 Dec

Our top choices for Cape Girardeau holiday homes

Living area

1. Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very good, (57 reviews)
"Great cute place. "
United States
Jeremy W.
The price is £83
includes taxes & fees
18 Aug - 19 Aug
Little Blue Cottage on Spanish
Exterior

2. 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.8 out of 10, Excellent, (43 reviews)
"Will definitely book again! Great location, comfortable stay."
United States
Pynktoria !.
The price is £234
includes taxes & fees
21 Aug - 22 Aug
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Coffee/tea maker, fridge, microwave, dishwasher

3. Beautifully Renovated Farmhouse in Jackson, MO

Beautifully Renovated Farmhouse in Jackson, MO
Jackson
9.4 out of 10, Exceptional, (3 reviews)
" great stay,property landscape nicely manicured, quiet and relaxing inside and outside of the the dwelling."
United States
Sandy S.
The price is £227
includes taxes & fees
24 Aug - 25 Aug
Beautifully Renovated Farmhouse in Jackson, MO
Pool

4. 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Cape Girardeau
9.6 out of 10, Exceptional, (10 reviews)
"Nice place, great times"
United States
Jace W.
The price is £411
includes taxes & fees
21 Aug - 22 Aug
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Interior

5. Cozy and Updated Farmhouse with King Suite

Cozy and Updated Farmhouse with King Suite
Anna
10.0 out of 10, Exceptional, (22 reviews)
"Nice little house that was perfect for our family of five plus our dog. We would stay here again if we found ourselves out this way again."
United States
Kyle
The price is £120
includes taxes & fees
18 Aug - 19 Aug
Cozy and Updated Farmhouse with King Suite
Exterior

6. The Weber Farm - Enjoy a beautiful 100 acre farm!

The Weber Farm - Enjoy a beautiful 100 acre farm!
Frohna
10.0 out of 10, Exceptional, (34 reviews)
"Wonderful time! "
United States
Alison C.
The price is £124
includes taxes & fees
18 Aug - 19 Aug
The Weber Farm - Enjoy a beautiful 100 acre farm!
Exterior detail

7. Stunning 2 bedroom in town, close to Shawnee National Forest

Stunning 2 bedroom in town, close to Shawnee National Forest
Jonesboro
10.0 out of 10, Exceptional, (11 reviews)
"Cool renovated property that keeps that old fashioned charm. Spacious living with all the amenities you need for a vacation stay."
United States
Dylan
The price is £208
includes taxes & fees
21 Aug - 22 Aug
Stunning 2 bedroom in town, close to Shawnee National Forest
Outdoor dining

8. Walk to Weddings-Wineries-Trails, Family Friendly Home in Downtown Alto Pass

Walk to Weddings-Wineries-Trails, Family Friendly Home in Downtown Alto Pass
Alto Pass
10.0 out of 10, Exceptional, (5 reviews)
"The house was very welcoming and clean. Very inviting for our short stay. "
United States
brian O.
The price is £191
includes taxes & fees
9 Sept - 10 Sept
Walk to Weddings-Wineries-Trails, Family Friendly Home in Downtown Alto Pass
Outdoor dining

9. Beautiful location in the secluded woods

Beautiful location in the secluded woods
Pomona
9.8 out of 10, Exceptional, (79 reviews)
"We had a great stay! Secluded cabin and a large property just the right size for a weekend away and within 20-30 minute driving distance of beautiful hiking trails/unique and delicious local restaurants! Would stay again. "
United States
Hanna S.
The price is £133
includes taxes & fees
24 Aug - 25 Aug
Beautiful location in the secluded woods
Outdoor dining

10. Rendelman Orchard's Farm Stay

Rendelman Orchard's Farm Stay
Alto Pass
9.8 out of 10, Exceptional, (14 reviews)
"The chickens and yard were absolutely amazing- wish we had more time to enjoy and explore the grounds! Our host was very nice and communicative. We loved the two wineries near by. There were some bugs inside when we checked in and throughout the evening but that’s to be expected on the farm. Appreciated the fly swatter and the light traps! Highly recommend this stay."
United States
Kayla F.
The price is £165
includes taxes & fees
16 Aug - 17 Aug
Rendelman Orchard's Farm Stay
Exterior

11. Magical Victorian near hiking / wine trail

Magical Victorian near hiking / wine trail
Anna
9.8 out of 10, Exceptional, (17 reviews)
"Lovely time, easy for our dog and for our family, did the tarot card reading that was recommended by host and it did not disappoint!"
United States
Elizabeth W.
The price is £253
includes taxes & fees
16 Aug - 17 Aug
Magical Victorian near hiking / wine trail
Exterior

12. Crossview Cottage - Has a direct view of the Bald Knob Cross Monument

Crossview Cottage - Has a direct view of the Bald Knob Cross Monument
Alto Pass
The price is £189
includes taxes & fees
18 Aug - 19 Aug
Crossview Cottage - Has a direct view of the Bald Knob Cross Monument
Living area

13. Pa’s House is an enjoyable, entirely remodeled, 2-bedroom farmhouse near Anna.

Pa’s House is an enjoyable, entirely remodeled, 2-bedroom farmhouse near Anna.
Anna
10.0 out of 10, Exceptional, (7 reviews)
"We greatly enjoyed our stay at this property. The communication and hospitality from the host was top notch. The property is beautiful and well maintained. The house was incredibly clean, well furnished, and cozy. Our family loved the rural setting and close proximity to the neighboring towns. Incredible value for all the amenities and features you get. We will definitely be back!"
United States
Aaron D.
The price is £219
includes taxes & fees
13 Sept - 14 Sept
Pa’s House is an enjoyable, entirely remodeled, 2-bedroom farmhouse near Anna.
Smart TV

14. Rent All 5 Suites at Peach Tree Inn

Rent All 5 Suites at Peach Tree Inn
Cobden
The price is £506
includes taxes & fees
25 Aug - 26 Aug
Rent All 5 Suites at Peach Tree Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Cape Girardeau Hotel Reviews

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

10/10 Excellent
"Property was clean a room was stocked. Had microwave refrigerator and a stove refrigerator had working ice maker. Great room for the price"
GISELE 2-night trip
Posted 9 hours ago
Candlewood Suites Cape Girardeau by IHG

Find out more about Cape Girardeau

Cape Girardeau Holiday Homes information

Number of reviews
259
Accommodation
67 Holiday Homes
Lowest Price
£83
Highest Price
£506