Title: Sikeston Depot Museum in Sikeston | Expedia.co.uk [Sikeston Depot Museum Hotels](https://expedia.co.uk/Sikeston-Depot-Museum-Hotels.0-l6305602-0.Travel-Guide-Filter-Hotels)[Flights to Sikeston](https://expedia.co.uk/Cheap-Flights-To-Sikeston.d6058766.Travel-Guide-Flights)[Sikeston Depot Museum Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Sikeston-Depot-Museum.d6305602.Car-Hire-Guide)[Sikeston Holidays](https://expedia.co.uk/Sikeston.d6058766.Holidays-City-Breaks) # Sikeston Depot Museum ## Visit Sikeston Depot Museum Activities [Sikeston travel guide](https://expedia.co.uk/Sikeston.dx6058766) --- --- ## Plan a trip to see Sikeston Depot Museum Price found within the past 48 hours. Click for updated prices. ![The Wildwood Hotel](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/800a6847_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Wildwood Hotel £944 per person 24 Mar - 29 Mar found 6 hours ago Return flight included Edinburgh (EDI) to St. Louis (STL) 9.2/10 Wonderful! (1,600 reviews) Clean room and easy parking. Reviewed on 2 Feb 2026 ![Ameristar Casino Resort and Spa](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/c42cf5fe_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Ameristar Casino Resort and Spa £1,107 per person 24 Mar - 29 Mar found 6 hours ago Return flight included Edinburgh (EDI) to St. Louis (STL) 8.4/10 Very Good! (1,006 reviews) Room was clean, plenty of space Reviewed on 11 Feb 2026 ![The Cheshire](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/b6ec06de_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Cheshire £1,076 per person 24 Mar - 29 Mar found 6 hours ago Return flight included Edinburgh (EDI) to St. Louis (STL) 8.6/10 Excellent! (1,002 reviews) I love the whole "English Tudor" vibe at the hotel. The room was clean and well-appointed. The staff is friendly and the hotel lounge is a fun place to unwind. Reviewed on 6 Feb 2026 ### Popular places to visit ![View of the Christopher S. Bond Bridge over Missouri River in Kansas City, from the riverfront park](https://images.trvl-media.com/place/553248621532655774/ae18e765-2c28-4c35-b4b0-74f1aaedcb22.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Riverfront Bridge Park Riverfront Bridge Park is just one of the places to see in Cape Girardeau, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savour the top-notch restaurants. [](https://expedia.co.uk/Riverfront-Bridge-Park-Cape-Girardeau.d553248621532655774.Attraction) #### Central Park Explore the great outdoors at Central Park, a lovely green space in Sikeston. While in this family-friendly area, you can savour the top-notch restaurants. [](https://expedia.co.uk/Central-Park-Sikeston.d6305608.Attraction) #### City of Miner Convention Center Learn about the events happening in City of Miner Convention Center during your trip to Miner. While in this relaxing area, you can savour the top-notch restaurants. [](https://expedia.co.uk/City-Of-Miner-Convention-Center-Sikeston.d818566100963352576.Attraction) #### Front Street Studio & Art Gallery You can spend time browsing the exhibits at Front Street Studio & Art Gallery during your travels in Blodgett. While in this family-friendly area, you can savour the top-notch restaurants. [](https://expedia.co.uk/Front-Street-Studio-Art-Gallery-Blodgett.d553248621532655753.Attraction) #### Stoddard County Civil War Memorial Cemetery Step back in time and learn more about local history with a stop at Stoddard County Civil War Memorial Cemetery in Dexter. While in this family-friendly area, you can enjoy the restaurants. [](https://expedia.co.uk/Stoddard-County-Civil-War-Memorial-Cemetery-Dexter.d553248621532655747.Attraction) #### Hunter-Dawson State Historic Site You can browse the exhibits at Hunter-Dawson State Historic Site, a museum with a story of its own, during your trip to New Madrid. Amble around the area's parks or experience its museums. [](https://expedia.co.uk/Hunter-Dawson-State-Historic-Site-New-Madrid.d553248621532655794.Attraction) --- ## Top Hotel Deals ## Check availability on hotels close to Sikeston Depot Museum [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6305602&startDate=2026-02-11&endDate=2026-02-12)[11 Feb - 12 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6305602&startDate=2026-02-11&endDate=2026-02-12) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6305602&startDate=2026-02-12&endDate=2026-02-13)[12 Feb - 13 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6305602&startDate=2026-02-12&endDate=2026-02-13) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6305602&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026)[13 Feb - 15 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6305602&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6305602&startDate=20%2F02%2F2026&endDate=22%2F02%2F2026)[20 Feb - 22 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6305602&startDate=20%2F02%2F2026&endDate=22%2F02%2F2026) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hampton Inn Sikeston 1240 Commerce Drive Sikeston MO [](https://expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Inn & Suites Sikeston, MO 2608 East Malone Ave, Miner Sikeston MO [](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Fairfield Inn & Suites by Marriott Sikeston](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Fairfield Inn & Suites by Marriott Sikeston 1239 Commerce Drive Sikeston MO [](https://expedia.co.uk/Sikeston-Hotels-Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Modern and Cozy Apartment with large windows and sunlight.](https://images.trvl-media.com/lodging/77000000/76030000/76020500/76020481/c7fd89d3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Modern and Cozy Apartment with large windows and sunlight. 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Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=DX_POI_Spring_PROMO_6305602)