A narrow cobblestone street lined with colorful buildings, shops, and a prominent white archway in the distance.

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Our top choices for Santa Cruz luxury hotels

1. Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
5.0 star property
Historical Center
9.4 out of 10, Exceptional, (1,001 reviews)
  • cleanliness
    Timeless elegance flourishes in a historic Seville hotel steps from the Royal Alcázar.
The price is £539
includes taxes & fees
3 Nov - 4 Nov
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

2. El Rey Moro Hotel Boutique

El Rey Moro Hotel Boutique
4.0 star property
Historical Center
9.4 out of 10, Exceptional, (971 reviews)
  • cleanliness
    Indulge in historic luxury steps from Royal Alcázar with deep soaking tubs, rooftop terrace views, and thoughtful boutique comforts.
The price is £190
includes taxes & fees
1 Nov - 2 Nov
El Rey Moro Hotel Boutique

3. EME Catedral Mercer Hotel

EME Catedral Mercer Hotel
5.0 star property
Historical Center
8.8 out of 10, Excellent, (1,002 reviews)
  • cleanliness
    Lavish retreat steps from Seville Cathedral featuring full-service spa treatments, poolside bar, and rooftop terrace with panoramic views.
The price is £174
includes taxes & fees
2 Nov - 3 Nov
EME Catedral Mercer Hotel

4. Hotel Mercer Sevilla 5 GL

Hotel Mercer Sevilla 5 GL
5.0 star property
Historical Center
10.0 out of 10, Exceptional, (180 reviews)
  • cleanliness
    Discover luxurious elegance in historic Seville where attentive staff, poolside relaxation, and boutique charm create an intimate escape.
The price is £352
includes taxes & fees
1 Nov - 2 Nov
Hotel Mercer Sevilla 5 GL

5. Hotel Colón Gran Meliá

Hotel Colón Gran Meliá
5.0 star property
Historical Center
9.6 out of 10, Exceptional, (1,002 reviews)
  • cleanliness
    Five-star serenity awaits at this luxury Seville hotel, where rooftop pool relaxation meets spa indulgence just steps from the cathedral.
The price is £256
includes taxes & fees
4 Nov - 5 Nov
Hotel Colón Gran Meliá

6. CoolRooms Palacio Villapanés 5 GL

CoolRooms Palacio Villapanés 5 GL
5.0 star property
Historical Center
9.6 out of 10, Exceptional, (1,000 reviews)
  • cleanliness
    Palatial luxury awaits at this 5-star boutique hotel featuring a full-service spa, seasonal outdoor pool, and rooftop terrace in Seville.
The price is £346
includes taxes & fees
1 Nov - 2 Nov
CoolRooms Palacio Villapanés 5 GL

7. Hotel Casa Palacio Don Ramón 5* GL by Kaizen Hoteles

Hotel Casa Palacio Don Ramón 5* GL by Kaizen Hoteles
5.0 star property
Historical Center
9.8 out of 10, Exceptional, (236 reviews)
  • cleanliness
    Discover colonial luxury in Seville's historic centre with facials, seasonal pool, and rooftop terrace just steps from iconic landmarks.
The price is £360
includes taxes & fees
4 Nov - 5 Nov
Hotel Casa Palacio Don Ramón 5* GL by Kaizen Hoteles

8. Cavalta Boutique Hotel – Small Luxury Hotel

Cavalta Boutique Hotel – Small Luxury Hotel
5.0 star property
Triana
9.8 out of 10, Exceptional, (135 reviews)
  • cleanliness
    Experience boutique luxury in Triana, where personalised service meets Mediterranean charm just steps from Seville's iconic landmarks.
The price is £256
includes taxes & fees
1 Nov - 2 Nov
Cavalta Boutique Hotel – Small Luxury Hotel

9. Thompson Seville, by Hyatt

Thompson Seville, by Hyatt
5.0 star property
Historical Center
10.0 out of 10, Exceptional, (1 review)
The price is £216
includes taxes & fees
3 Nov - 4 Nov
Thompson Seville, by Hyatt

10. Hotel Lobby

Hotel Lobby
5.0 star property
Historical Center
9.6 out of 10, Exceptional, (620 reviews)
  • cleanliness
    Immerse in elegant comfort near Seville Cathedral, where luxurious rooms with deep soaking tubs meet refreshing poolside cocktails.
The price is £168
includes taxes & fees
3 Nov - 4 Nov
Hotel Lobby
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Santa Cruz

Santa Cruzand its attractions for luxury travelers

In the charming Santa Cruz neighbourhood of Spain, luxury travellers can indulge in a blend of culture, gastronomy, and relaxation. Begin your day with a visit to the stunning Plaza de la Catedral, where the magnificent cathedral showcases intricate architecture, perfect for a leisurely stroll or a sophisticated photo op. For art enthusiasts, the nearby Museo de Bellas Artes offers a captivating collection of Spanish masterpieces, providing an ideal backdrop for an afternoon of cultural enrichment. After soaking in the sights, unwind at the picturesque Parque García Sanabria, a lush oasis featuring exotic plants and a beautiful lake, perfect for a picnic or a quiet moment. When it comes to dining, Santa Cruz boasts high-end restaurants such as La Casa de la Pasta, where you can savour exquisite local flavours in an elegant setting. After a day of exploration, retreat to one of the luxury hotels in the area, where you can expect personalised service and lavish amenities. For instance, hotels like Iberostar Grand Mencey offer opulent spa facilities and gourmet dining options, ensuring that your stay is as relaxing as it is memorable. Experience the perfect blend of comfort and sophistication, all while being just steps away from the vibrant life of Santa Cruz.

Top Santa Cruz Hotel Reviews

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Santa Cruz?
While you're visiting, you might want to think about enjoying the monuments and museums, which Santa Cruz is known for.
What's the best luxury place to stay in Santa Cruz?
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville is a luxury hotel with 2 restaurants and valet parking, and it's a popular choice for Expedia travellers looking for an elegant place to stay. EME Catedral Mercer Hotel and El Rey Moro Hotel Boutique are other upscale choices for your trip.
What's there to see and do in Santa Cruz?
Take in the sights and attractions that Santa Cruz offers with a visit to Giralda Tower, Convent of the Incarnation and Triunfo Plaza. If you have a little extra time during your trip, you might want to make a stop at Puerta del Príncipe and General Archive of the Indies.
How can I get around Santa Cruz?
It's easier to get around town comfortably when you know your options. Head to Puerta Jerez Tram Stop for metro travel.

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