Title: TOP Luxury Hotels in Santa Cruz Island for 2025 - Santa Cruz Island Upscale Hotels | Expedia.co.uk [Santa Cruz Island Travel Guide](https://expedia.co.uk/Santa-Cruz-Island.dx6053670)[Hotels in Santa Cruz Island](https://expedia.co.uk/Santa-Cruz-Island-Hotels.d6053670.Travel-Guide-Hotels)[Holiday Rentals in Santa Cruz Island](https://expedia.co.uk/Santa-Cruz-Island-Holiday-Rentals.d6053670.Travel-Guide-HolidayRentals)[Flights to Santa Cruz Island](https://expedia.co.uk/Cheap-Flights-To-Santa-Cruz-Island.d6053670.Travel-Guide-Flights)[Things to do in Santa Cruz Island](https://expedia.co.uk/Things-To-Do-In-Santa-Cruz-Island.d6053670.Travel-Guide-Activities)[Santa Cruz Island Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Cruz-Island.d6053670.Car-Hire-Guide)[Santa Cruz Island Holidays](https://expedia.co.uk/Santa-Cruz-Island.d6053670.Holidays-City-Breaks) ![](https://mediaim.expedia.com/destination/1/04d5e478ee175ffd174b1e23d51916f4.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Santa Cruz Island ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Cruz Island Luxury Hotels Tonight [12 Oct - 13 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6053670&startDate=2025-10-12&endDate=2025-10-13&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [13 Oct - 14 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6053670&startDate=2025-10-13&endDate=2025-10-14&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6053670&startDate=2025-10-17&endDate=2025-10-19&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [24 Oct - 26 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6053670&startDate=2025-10-24&endDate=2025-10-26&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Santa Cruz Island Luxury Hotels ![Exterior](https://images.trvl-media.com/lodging/11000000/10090000/10087200/10087137/08eca00e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach nearby, white sand](https://images.trvl-media.com/lodging/11000000/10090000/10087200/10087137/bf30a401.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Double Beds | Premium bedding, minibar, individually furnished, bed sheets](https://images.trvl-media.com/lodging/11000000/10090000/10087200/10087137/d196b036.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10090000/10087200/10087137/7d701bfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Ninfa Puerto Ayora 8.4/10 Very good (213) "Great hotel to use as your base while exploring Galapagos, and a lovely pool, hot tub and bar to come home to at the end of the day" [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Hotel-Ninfa.h10087137.Hotel-Information) ![Breakfast, lunch, dinner served; international cuisine, sea views ](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/4a332d25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite Signature | Bathroom | Shower, designer toiletries, hair dryer, bathrobes](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/09b4fe48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite Signature | Terrace/patio](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/f9620d53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/92acdc7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Blu Galapagos Sustainable Waterfront Lodge Puerto Ayora 8.8/10 Excellent (120) "We had a great stay at Blu Galapagos. Loved the location and our room was perfect - Great view, well maintained and had a king bed. Even if the description says queen bed and the picture looks like a king, you can trust the picture. Morning breakfast with iguanas and seals, and all day Galapagos coffee availability made this stay special. " £130 3 Nov - 4 Nov [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Galapagos-Habitat-By-Eco-Luxury-Group.h2057779.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1870000/1862600/1862515/62b50762.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/2000000/1870000/1862600/1862515/75f9c54d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Double Room | Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1870000/1862600/1862515/w2236h1687x0y0-81876455.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Massages](https://images.trvl-media.com/lodging/2000000/1870000/1862600/1862515/7c225fcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Finch Bay Galapagos Hotel Puerto Ayora 9.2/10 Wonderful (87) "Beautiful resort, impeccably clean, very kind and enthusiastic staff. Delicious restaurant. 5 stars all around, we will definitely return!" £381 4 Nov - 5 Nov [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Finch-Bay-Galapagos-Hotel.h1862515.Hotel-Information) ![Balcony](https://images.trvl-media.com/lodging/10000000/9440000/9438300/9438290/9627c360.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9440000/9438300/9438290/dbe9c9f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Triple Room | Free WiFi](https://images.trvl-media.com/lodging/10000000/9440000/9438300/9438290/9081fe63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/10000000/9440000/9438300/9438290/abfd6b7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Flightless Cormorant Puerto Ayora 5.6/10 (18) "Despite the Expedia confirmation and my correspondence with the hotel prior to arrival, when we arrived first we had to wait over an hour for anybody to arrive at the reception, only to hear that our reservation does not exist. After a tiring trip we had to run around the city to find any hotel that looks acceptable and has free rooms left. All that with full luggage, burning noon sun and a child. Stay away from that hotel! Shame on Expedia that they sell a hotel that claims no work with... [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Flightless-Cormorant.h9438290.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-26&endDate=2025-10-27®ionId=6053670&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Santa Cruz Island ### Santa Cruz Islandand its attractions for luxury travelers Santa Cruz Island, a jewel of the Galápagos archipelago, offers an exquisite blend of adventure and relaxation for luxury travellers. Begin your journey at the Charles Darwin Research Station, where you can engage with conservation efforts and meet the famous Galápagos tortoises, providing a unique insight into the archipelago's ecological importance. For those seeking an exhilarating experience, the pristine beaches of Tortuga Bay allow for kayaking and sunbathing amidst stunning natural beauty; its powdery sands and crystal-clear waters create a serene escape. Adventurous spirits can explore the lava tunnels of Santa Cruz, an otherworldly landscape formed by volcanic activity, offering a fascinating glimpse into the geological history of the island. For a taste of local culture, visit the bustling fish market in Puerto Ayora, where you can savour fresh seafood while observing playful sea lions lounging nearby. Finally, unwind with a private yacht excursion to nearby crystalline coves, perfect for snorkelling alongside vibrant marine life. The premier area to stay for a luxurious experience is in the heart of Puerto Ayora, where high-end hotels offer impeccable service and stunning views of the waterfront. Here, you can indulge in gourmet dining, spa treatments, and personalised excursions, ensuring every moment of your stay is tailored to pamper and delight. ## Top Santa Cruz Island Hotel Reviews ![Blu Galapagos Sustainable Waterfront Lodge](//images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/4a332d25_y.jpg) ### Blu Galapagos Sustainable Waterfront Lodge 10/10 Excellent "I was very pleased with Blu Galapagos. The rooms were very clean, great view, very helpful staff. My only recommendation would be to not use the tour company in the hotel. I booked a tour after being very specific in what I wanted to see. I was assured it was possible but once I arrived the tour guide explained there was not enough time within my limited time to see what I came for. Very disappointed. Was not offered any refund or other compensation. The tour was not inexpensive and feel I was completely lied to and intentionally misled. " [](https://expedia.co.uk/Puerto-Ayora-Hotels-Galapagos-Habitat-By-Eco-Luxury-Group.h2057779.Hotel-Information) ![Hotel Ninfa](//images.trvl-media.com/lodging/11000000/10090000/10087200/10087137/08eca00e_y.jpg) ### Hotel Ninfa 10/10 Excellent "Great" [](https://expedia.co.uk/Puerto-Ayora-Hotels-Hotel-Ninfa.h10087137.Hotel-Information) ![Finch Bay Galapagos Hotel](//images.trvl-media.com/lodging/2000000/1870000/1862600/1862515/62b50762_y.jpg) ### Finch Bay Galapagos Hotel 10/10 Excellent "Beautiful resort, impeccably clean, very kind and enthusiastic staff. Delicious restaurant. 5 stars all around, we will definitely return!" 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