Santa Cruz Island Holidays from £1,847

Book a Hotel + Flight or Car together to unlock savings

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    Better together

    Save up to £335 when you book a flight and hotel together*
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    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Rest easy

    Packages with flights are ATOL protected

Top Santa Cruz Island Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Hotel Albemarle
Royal Palm Galapagos, Curio Collection Hotel by Hilton
Galapagos Sea Star
Angermeyer Waterfront Inn
Yellow Heron house

Santa Cruz Island Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Seymour Airport (GPS)

Top hotels in Santa Cruz Island

Hotel Fiesta

Hotel Fiesta

3.5 out of 5
Calle Moises Brito y Juan Montalvo, Puerto Ayora, Galapagos
Fully refundableReserve now, pay when you stay
The price is £116 per night from 10 Aug to 11 Aug
£116
10 Aug - 11 Aug
9/10 Wonderful! (351 reviews)
Helpful Staff and Great Location
"The staff was very helpful and the hotel was in a safe and quiet location. The pool was cold but nice and the pillows were some of the most comfortable I’ve ever slept on."

Reviewed on 25 Jul 2025

Hotel Fiesta
Ikala Galapagos Hotel

Ikala Galapagos Hotel

4 out of 5
Tomas de Berlanga 110 y Moises Brito, Puerto Ayora, Ecuador
The price is £198 per night from 1 Aug to 2 Aug
£198
1 Aug - 2 Aug
9.6/10 Exceptional! (114 reviews)
"Beds too hard"

Reviewed on 28 May 2025

Ikala Galapagos Hotel
El Barranco Galapagos

El Barranco Galapagos

2.5 out of 5
Los colonos, Puerto Ayora, Galapagos
The price is £160 per night from 11 Aug to 12 Aug
£160
11 Aug - 12 Aug
9.2/10 Wonderful! (11 reviews)
"amazing hotel and the best service the pool is the perfect spot to see seals, sea turtles, sting rays, sharks and pelicans , at night it’s quiet and the room was perfect. loved especially my balcony overlooking the docks."

Reviewed on 6 Jul 2025

El Barranco Galapagos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

What to do in Santa Cruz Island

Frequently asked questions

Why should I book my Santa Cruz Island holiday with Expedia?
With top-value airfares, car hire and hotel options all in one convenient place, Expedia makes planning your Santa Cruz Island adventure easy. Moreover, we can help you bundle your bookings into a package holiday so you can enjoy even more savings. Select from fabulous stays, add your flights and/or a car hire (and maybe even some exciting activities!) and land unbeatable prices. Need to change your plans? Expedia has a flexible cancellation policy for many reservations. To find out more, visit our Customer Service Portal link.
How do I get a cheap holiday to Santa Cruz Island?
Combining your hotel and flight with Expedia won't just save you time — it'll save you a few pounds too. A Santa Cruz Island holiday makes it easy to create your dream adventure. With more than 400 airlines throughout the world to choose from, finding flights that suit your schedule will be no sweat. Not only that, we've got over 321,000 properties globally to choose from. Now that's what you call choice. No matter who you are, Expedia puts more of the world within your reach. Learn more about how you can save money on your next holiday when you combine your hotel and flight bookings with Expedia.
What should I do on my Santa Cruz Island holiday?
Plan your next holiday in Santa Cruz Island around popular attractions such as Tortuga Bay Beach and Charles Darwin Research Station. Many tourists also highly recommend Playa de los Alemanes and Malecon.
Do I need a visa for my Santa Cruz Island holiday?
Look up the latest rules on official government websites. Your nationality and whether you're travelling for study, business or leisure will determine if you'll need a visa for Santa Cruz Island. Get familiar with the application process, including any required documentation, turnaround times and fees. Submit your application well in advance to allow plenty of time for processing. Some visas may take several weeks or even months to obtain, depending on the country.
What should I wear on my Santa Cruz Island holiday?
Consider the sorts of activities you have planned during your Santa Cruz Island trip and take versatile pieces that you can mix and match. For fashion inspiration or information on any dress codes, look up a few style blogs or social media accounts.
What does an Expedia Santa Cruz Island holiday include?
With Expedia, you can choose a combination of flights, hotels and car hires to build your ideal Santa Cruz Island package. Once you've made your booking, simply add on all the fun stuff like tours and experiences. Don't forget — the more you bundle, the bigger the savings! Explore a variety of styles on Expedia and find the right fit for you and your crew. From the most sought-after property types, like hotels and apartments, to many other options, you'll find loads of holiday retreats in Santa Cruz Island to select from so you can plan your adventure just the way you like it.
Does Expedia offer Book Now, Pay Later Santa Cruz Island holidays?
We certainly do. Expedia has teamed up with online lender Klarna to help you conveniently pay for your holiday in manageable instalments. Simply select the payment plan that works for you during the checkout process and take the stress out of budgeting for your next trip. Remember to bundle your flights, car hire and accommodation with Expedia to get the biggest bang for your travel buck. Take a look at our flexible payment options below:

  • Pay monthly holidays: Klarna offers easy monthly payment plans that suit all budgets, so you can escape on that well-deserved holiday sooner.
  • No-deposit holidays: Clicking on the "book now" button is easier with this plan. With no upfront fee for your getaway, you can Book Now, Pay Later and start packing your bags.

Can I choose my airline with a Santa Cruz Island Expedia holiday?
With a holiday package, you're the boss. Whether you want to fly to Santa Cruz Island in economy or first class, simply choose from the available airline options. Expedia has access to over 400 partner airlines all over the world.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.