Santa Cruz Island Holidays from £339

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Top Santa Cruz Island Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Twin Hotel Galapagos

Twin Hotel Galapagos

3 out of 5
Price was £413, price is now £339 per person
£339
per person
7 Jun - 10 Jun
found 12 hours ago
Return flight included
Quito (UIO) to Isla Baltra (GPS)
8.4/10 Very Good! (45 reviews)
This hotle is fantastic lovely people that work here Very helpful with booking tours ect . To rooms are so fantastic, comfortable bed can’t get any better and good breakfast.

Reviewed on 19 Jul 2025

Galapagos Native

Galapagos Native

3 out of 5
Price was £533, price is now £380 per person
£380
per person
7 Jun - 10 Jun
found 12 hours ago
Return flight included
Quito (UIO) to Isla Baltra (GPS)
7.8/10 Good! (94 reviews)
Confortablenstop over for a family

Reviewed on 28 Dec 2024

Angermeyer Waterfront Inn

Angermeyer Waterfront Inn

3.5 out of 5
Price was £668, price is now £538 per person
£538
per person
7 Jun - 10 Jun
found 12 hours ago
Return flight included
Quito (UIO) to Isla Baltra (GPS)
9.4/10 Exceptional! (130 reviews)
The staff goes far beyond in making your stay enjoyable. They were so helpful in facilitating our many adventures

Reviewed on 14 Mar 2026

Galapagos Coliving Ecuador Casa Tuna

Galapagos Coliving Ecuador Casa Tuna

3 out of 5
Price was £475, price is now £405 per person
£405
per person
7 Jun - 10 Jun
found 12 hours ago
Return flight included
Quito (UIO) to Isla Baltra (GPS)
No reviews
Palo Santo Galapagos Hotel

Palo Santo Galapagos Hotel

3 out of 5
Price was £567, price is now £492 per person
£492
per person
7 Jun - 10 Jun
found 12 hours ago
Return flight included
Quito (UIO) to Isla Baltra (GPS)
8.4/10 Very Good! (22 reviews)
The stay at Palo Santo was excellent! The staff definitely made us feel welcomed and helped us out with the luggage to and from the boat. The room was nice and the breakfast was delicious each morning. The property was quiet and a little run down in areas but nothing that mattered when your in the Galapagos. Surprised it was not busier because the location was fantastic!

Reviewed on 24 Feb 2026

Santa Cruz Island Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Seymour Airport (GPS)

Top hotels in Santa Cruz Island

Hotel Fiesta

Hotel Fiesta

3.5 out of 5
Calle Moises Brito y Juan Montalvo Puerto Ayora Galapagos
Fully refundableReserve now, pay when you stay
The price is £116 per night from 10 Apr to 11 Apr
£116
10 Apr - 11 Apr
Hotel Fiesta
Maidith Galapagos Inn

Maidith Galapagos Inn

3 out of 5
Calle Cucuve #341 y Seymour, Santa Cruz Puerto Ayora Galápagos
The price is £107 per night from 9 Apr to 10 Apr
£107
9 Apr - 10 Apr
9.8/10 Exceptional! (120 reviews)
Very helpful staff. The water in the room was very convenient.

Reviewed on 16 Mar 2026

Maidith Galapagos Inn
Hotel el descanso del Guia

Hotel el descanso del Guia

3.5 out of 5
Calle Delfin, Barrio el Mirador Puerto Ayora Galapagos
The price is £83 per night from 2 Apr to 3 Apr
£83
2 Apr - 3 Apr
8.8/10 Excellent! (193 reviews)
The staff was amazing, so attentive and kind!

Reviewed on 25 Feb 2026

Hotel el descanso del Guia
See all 216 properties in Santa Cruz Island
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Popular places to visit

#aquatrove

Tortuga Bay Beach

If a restful holiday is part of your travel plans, Tortuga Bay Beach might be the perfect place to visit during your trip to Bella Vista. While you're in the area, wander around the parks.

Tortuga Bay Beach

Playa de los Alemanes

If a restful holiday is part of your travel plans, Playa de los Alemanes might be the perfect place to visit during your trip to Puerto Ayora. While you're here, you can savour the top-notch restaurants.

Playa de los Alemanes

What to do in Santa Cruz Island

Transfer from Santa Cruz Island to San Cristobal Island

Transfer from Santa Cruz Island to San Cristobal Island

£42
per adult
Transfer from Santa Cruz Island to San Cristobal Island
Bay Tour in Santa Cruz - Galapagos Islands

Bay Tour in Santa Cruz - Galapagos Islands

£44
per adult
100% of travellers recommend
Bay Tour in Santa Cruz - Galapagos Islands
El Chato 2 Reserve Admission Ticket in Santa Cruz Island

El Chato 2 Reserve Admission Ticket in Santa Cruz Island

£6
per traveller
El Chato 2 Reserve Admission Ticket in Santa Cruz Island
See all activities in Santa Cruz Island

Frequently asked questions

Can I cancel my flight booking to Santa Cruz Island due to COVID-19?
Many airlines now provide more flexibility due to COVID-19. Our convenient Customer Service Portal will help answer most queries about which policies apply to your flight. It's also worth scanning over the terms and conditions of your chosen carrier — preferably before locking in your seat!
What's the best way to find cheap flights to Santa Cruz Island that have flexible change policies?
We know that travel arrangements can change from one day to the next, so choosing a flexible fare with Expedia is always a wise idea. Simply tick the "No change fee" box below the "Flexible change policies" filter. Your low-cost, flexible flight to Santa Cruz Island is only a few clicks away.
What are some of the general tips for travellers to Santa Cruz Island during the COVID-19 outbreak?
The COVID-19 pandemic has brought about big changes to the way we travel. If you're planning an escape to Santa Cruz Island, the following tips will help you navigate this new travelling reality:
  • Research if any travel restrictions apply to your origin and destination before booking your flight. Also check if there are any requirements you'll have to follow on arrival, such as health testing.
  • Wear a face mask even during airport screening. A TSA officer will require you to adjust your mask for identification purposes.
  • You're no longer required to hand your boarding pass (paper or electronic) directly to a TSA officer. Rather, you should position the pass on the reader and then hold it up to allow the agent to visually inspect it.
  • You are now allowed to take one container of hand sanitizer up to 12 oz (350 ml) in your carry-on luggage. This will need to be removed for X-ray scanning.
  • To minimize handling during the screening process, place items such as your phone, wallet and keys into your carry-on instead of the bins.
  • Separate any food you have for screening. Food items often trigger the alarm. Putting them in a clear plastic bag and into a bin reduces the need for a TSA agent to touch and inspect your belongings.

Which airlines fly to Santa Cruz Island?
LATAM Airlines Ecuador runs flights into or near Santa Cruz Island, including 60 that arrive at Seymour Airport (GPS) each month. Choose your holiday dates and then secure your seat early for the best price.
How can I find cheap tickets to Santa Cruz Island?
For the best deal to Santa Cruz Island, book well ahead of time. Also make use of Expedia's "flexible dates" link at the top of your search results. This will display prices for similar time frames. In the last seven days, was the lowest price for a flight to Santa Cruz Island.
How much is a flight to Santa Cruz Island?
If you were flying one way from (), you could've picked up a cheap ticket for in the last seven days. Round-trip flights to Santa Cruz Island ranged from only to during this same period.
What are the most popular airports to fly into in Santa Cruz Island?
Seymour Airport (GPS) is the main entryway for people travelling into and out of Santa Cruz Island. Approximately 95 flights a month touch down at this airport.
When is the cheapest time to fly to Santa Cruz Island?
Departing on a Tuesday, followed by a Monday, is generally the best way to bag the cheapest fare. Avoid the weekends if you can, because Saturday is typically the most expensive day of the week. Spend the cash you saved having a good time in Santa Cruz Island instead!
How much is a plane ticket to Santa Cruz Island?
In the last seven days, plane tickets to Santa Cruz Island fluctuated between and . Prices rise as your travel date nears, so grab a terrific deal today.
Which airlines with flights to Santa Cruz Island employ COVID-19 cleanliness policies?
Like most things, plane travel is looking very different nowadays. Airlines worldwide have adopted a range of measures, including social distancing, to slow the spread of COVID-19. Here are some of them:
  • LATAM Airlines Ecuador - this airline is known for providing passenger masks and cleaning with disinfectant.
  • Avianca - this airline is known for conducting passenger temperature checks and cleaning with disinfectant.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.