Title: TOP Business Hotels in Santa Cruz Island for 2026 | Expedia.co.uk [Santa Cruz Island Travel Guide](https://expedia.co.uk/Santa-Cruz-Island.dx6053670)[Hotels in Santa Cruz Island](https://expedia.co.uk/Santa-Cruz-Island-Hotels.d6053670.Travel-Guide-Hotels)[Holiday Rentals in Santa Cruz Island](https://expedia.co.uk/Santa-Cruz-Island-Holiday-Rentals.d6053670.Travel-Guide-HolidayRentals)[Flights to Santa Cruz Island](https://expedia.co.uk/Cheap-Flights-To-Santa-Cruz-Island.d6053670.Travel-Guide-Flights)[Things to do in Santa Cruz Island](https://expedia.co.uk/Things-To-Do-In-Santa-Cruz-Island.d6053670.Travel-Guide-Activities)[Santa Cruz Island Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Cruz-Island.d6053670.Car-Hire-Guide)[Santa Cruz Island Holidays](https://expedia.co.uk/Santa-Cruz-Island.d6053670.Holidays-City-Breaks) ![Galapagos Marine Iguana walking and swimming on Tortuga bay. Marine iguanas on beach on Santa Cruz Island, Galapagos Islands. Animals, wildlife and amazing nature in Ecuador, South America](https://images.trvl-media.com/place/6053670/54bcca80-11e8-424a-9353-2c1a8014c5d5.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Business Hotels in Santa Cruz Island - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Cruz Island Business Hotels Tonight [18 Dec - 19 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6053670&startDate=2025-12-18&endDate=2025-12-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [19 Dec - 20 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6053670&startDate=2025-12-19&endDate=2025-12-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [19 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6053670&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6053670&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Santa Cruz Island business-friendly hotels ![Standard Triple Room | In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/2ca19af6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/7e3fbe48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/d088e7ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room | Bathroom | Shower, free toiletries, hair dryer, slippers](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/e94fe441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Capitan Max B&B [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Capitan-Max-BB.h14716616.Hotel-Information) Puerto Ayora 9.8/10 Exceptional (197) "Good location and the staff was friendly and nice. The room was clean and quiet. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) thuy [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Capitan-Max-BB.h14716616.Hotel-Information) ![Breakfast, dinner served; local and international cuisine, sea views ](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/f2307f3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/2f16a828.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/a685ce77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Duplex | View from room](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/5dea777b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ikala Galapagos Hotel [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Ikala-Galapagos-Hotel.h23688395.Hotel-Information) Puerto Ayora 9.6/10 Exceptional (126) "Nice clean hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marco [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Ikala-Galapagos-Hotel.h23688395.Hotel-Information) ![Sun deck](https://images.trvl-media.com/lodging/5000000/4470000/4460600/4460518/15773cf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4470000/4460600/4460518/7411fddc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; pool views ](https://images.trvl-media.com/lodging/5000000/4470000/4460600/4460518/638e859c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room Ocean View Solymar Tower | Premium bedding, free minibar, in-room safe, individually decorated](https://images.trvl-media.com/lodging/5000000/4470000/4460600/4460518/7a0a413c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Solymar [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Hotel-Solymar.h4460518.Hotel-Information) Puerto Ayora 7.8/10 Good (59) "Great place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) VISHAL [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Hotel-Solymar.h4460518.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/18000000/17530000/17525300/17525206/48310af4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/18000000/17530000/17525300/17525206/b8350306.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/18000000/17530000/17525300/17525206/6c75b74b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Room, 2 Bedrooms | 1 bedroom, Egyptian cotton sheets, premium bedding, minibar](https://images.trvl-media.com/lodging/18000000/17530000/17525300/17525206/11f377c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel el descanso del Guia [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Hotel-El-Descanso-Del-Guia.h17525206.Hotel-Information) Puerto Ayora 8.8/10 Excellent (174) "Beautiful and spacious family room. Good breakfast and the staff is courteous. I highly recommend this hotel. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susanna [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Hotel-El-Descanso-Del-Guia.h17525206.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/92acdc7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine, sea views ](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/1d2d0c5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite Signature | In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/f83773fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite Signature | In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/d5ba3cfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Blu Galapagos Sustainable Waterfront Lodge [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Galapagos-Habitat-By-Eco-Luxury-Group.h2057779.Hotel-Information) Puerto Ayora 8.8/10 Excellent (122) "Beautiful property " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) David £181 20 Dec - 21 Dec [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Galapagos-Habitat-By-Eco-Luxury-Group.h2057779.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/13000000/12540000/12535100/12535025/67b1e811.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 8:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/13000000/12540000/12535100/12535025/d9e53b62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exclusive Villa, 1 King Bed | Premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/13000000/12540000/12535100/12535025/bec5832f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Villa, 1 King Bed | Premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/13000000/12540000/12535100/12535025/775239d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Royal Palm Galapagos, Curio Collection Hotel by Hilton [](https://www.expedia.co.uk/Santa-Rosa-Hotels-The-Royal-Palm-Hotel.h12535025.Hotel-Information) Santa Rosa 9.2/10 Wonderful (52) "The best part about staying at Royal Palms Galapagos was the staff. They were all friendly and helpful, making their best effort to make our stay enjoyable. They remembered our dietary restrictions and would point out if a dish had food we couldn’t eat. The facilities were very nice, and cleaned by friendly staff. The property grounds were serene and lovely. We thoroughly enjoyed our visit and would definitely choose the Royal Palms again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laureen £222 20 Dec - 21 Dec [](https://www.expedia.co.uk/Santa-Rosa-Hotels-The-Royal-Palm-Hotel.h12535025.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/15000000/14740000/14734400/14734307/7c8dc193.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/15000000/14740000/14734400/14734307/3eff65ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/15000000/14740000/14734400/14734307/f3ace51e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/15000000/14740000/14734400/14734307/27568355.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Suymar Ecolodge Galapagos [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Suymar-Ecolodge-Galapagos.h14734307.Hotel-Information) Bella Vista 9.0/10 Wonderful (14) "Incredible stay - would highly recommend this to anyone looking to stay a little out of the port area but not too far" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Porcia [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Suymar-Ecolodge-Galapagos.h14734307.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/18000000/17520000/17516800/17516766/ca3d4359.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17520000/17516800/17516766/b42c7514.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite, 2 Bedrooms, Garden View | Private kitchen | Cookware/dishes/utensils](https://images.trvl-media.com/lodging/18000000/17520000/17516800/17516766/a94dbde9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Twin Room, 2 Single Beds | Down duvets, desk, laptop workspace, soundproofing](https://images.trvl-media.com/lodging/18000000/17520000/17516800/17516766/fb031bbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lava House Hostal [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Lava-House-Hostal.h17516766.Hotel-Information) Puerto Ayora 9.4/10 Exceptional (52) "I stayed here twice. Both times highly satisfactory. Staff was very friendly and accommodatding. The rooms and garden area are in excellent upkeep and pleasant to hang out in hammocks or seating arrangements. The owners are very kind people, who even helped me organize a free ride back to the airport upon my departure (a relative happened to also take a flight off the island). I highly recommend this establishment. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Irmgard [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Lava-House-Hostal.h17516766.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/17000000/16770000/16761000/16760931/2a617ff8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/17000000/16770000/16761000/16760931/4a7fc99c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/17000000/16770000/16761000/16760931/d3bfda83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/17000000/16770000/16761000/16760931/2e4ce3f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Deja Vu [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-HOTEL-DEJA-VU.h16760931.Hotel-Information) Puerto Ayora 7.6/10 Good (28) "excellent service, the staff is very friendly 🙂 good location, you can walk to the main street" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Danaee [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-HOTEL-DEJA-VU.h16760931.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/14000000/13110000/13104300/13104250/5979c959.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/14000000/13110000/13104300/13104250/c884069e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/14000000/13110000/13104300/13104250/e303d191.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Local cuisine](https://images.trvl-media.com/lodging/14000000/13110000/13104300/13104250/514bb8aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palo Santo Galapagos Hotel [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Palo-Santo-Galapagos-Hotel.h13104250.Hotel-Information) Puerto Ayora 8.6/10 Excellent (17) "This is a really nice property, but for me a pool is very important when I stay at a resort. The pool water was cloudy and not very appealing/inviting. The area around the pool itself was great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wesley £177 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Palo-Santo-Galapagos-Hotel.h13104250.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-01&endDate=2026-01-02®ionId=6053670&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Santa Cruz Island Hotel Reviews ![Hotel el descanso del Guia](https://images.trvl-media.com/lodging/18000000/17530000/17525300/17525206/b6171efd_y.jpg) ### Hotel el descanso del Guia 10/10 Excellent "What really stood out was the exceptional customer service. Everyone was friendly, professional, and always willing to help with anything I needed. The location was perfect, and the atmosphere made my stay Monica" [](https://expedia.co.uk/Puerto-Ayora-Hotels-Hotel-El-Descanso-Del-Guia.h17525206.Hotel-Information) ![Royal Palm Galapagos, Curio Collection Hotel by Hilton](https://images.trvl-media.com/lodging/13000000/12540000/12535100/12535025/215f955b_y.jpg) ### Royal Palm Galapagos, Curio Collection Hotel by Hilton 10/10 Excellent "The best part about staying at Royal Palms Galapagos was the staff. They were all friendly and helpful, making their best effort to make our stay enjoyable. They remembered our dietary restrictions and would point out if a dish had food we couldn’t eat. The facilities were very nice, and cleaned by friendly staff. The property grounds were serene and lovely. We thoroughly enjoyed our visit and would definitely choose the Royal Palms again." [](https://expedia.co.uk/Santa-Rosa-Hotels-The-Royal-Palm-Hotel.h12535025.Hotel-Information) ![Finch Bay Galapagos Hotel](https://images.trvl-media.com/lodging/2000000/1870000/1862600/1862515/62b50762_y.jpg) ### Finch Bay Galapagos Hotel 10/10 Excellent "Beautiful resort, impeccably clean, very kind and enthusiastic staff. Delicious restaurant. 5 stars all around, we will definitely return!" [](https://expedia.co.uk/Puerto-Ayora-Hotels-Finch-Bay-Galapagos-Hotel.h1862515.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - [1 Star Hotels in Santa Fe Island ](https://www.expedia.co.uk/1Star-Santa-Fe-Island-Hotels.s10-0-d6336630.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Santa Fe Island ](https://www.expedia.co.uk/2Star-Santa-Fe-Island-Hotels.s20-0-d6336630.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Santa Fe Island ](https://www.expedia.co.uk/3Star-Santa-Fe-Island-Hotels.s30-0-d6336630.Travel-Guide-Filter-Hotels) - [4 Star Hotels in North Seymour Island ](https://www.expedia.co.uk/4Star-North-Seymour-Island-Hotels.s40-0-d6336659.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Santa Fe Island ](https://www.expedia.co.uk/4Star-Santa-Fe-Island-Hotels.s40-0-d6336630.Travel-Guide-Filter-Hotels) - [5 Star Hotels in North Seymour Island ](https://www.expedia.co.uk/5Star-North-Seymour-Island-Hotels.s50-0-d6336659.Travel-Guide-Filter-Hotels) - 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