Title: TOP Boutique Hotels in Santa Cruz Island for 2026 | Expedia.co.uk [Santa Cruz Island Travel Guide](https://expedia.co.uk/Santa-Cruz-Island.dx6053670)[Hotels in Santa Cruz Island](https://expedia.co.uk/Santa-Cruz-Island-Hotels.d6053670.Travel-Guide-Hotels)[Holiday Rentals in Santa Cruz Island](https://expedia.co.uk/Santa-Cruz-Island-Holiday-Rentals.d6053670.Travel-Guide-HolidayRentals)[Flights to Santa Cruz Island](https://expedia.co.uk/Cheap-Flights-To-Santa-Cruz-Island.d6053670.Travel-Guide-Flights)[Things to do in Santa Cruz Island](https://expedia.co.uk/Things-To-Do-In-Santa-Cruz-Island.d6053670.Travel-Guide-Activities)[Santa Cruz Island Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Cruz-Island.d6053670.Car-Hire-Guide)[Santa Cruz Island Holidays](https://expedia.co.uk/Santa-Cruz-Island.d6053670.Holidays-City-Breaks) ![Galapagos Marine Iguana walking and swimming on Tortuga bay. Marine iguanas on beach on Santa Cruz Island, Galapagos Islands. Animals, wildlife and amazing nature in Ecuador, South America](https://images.trvl-media.com/place/6053670/54bcca80-11e8-424a-9353-2c1a8014c5d5.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Boutique Hotels in Santa Cruz Island - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Cruz Island Boutique Hotels Tonight [19 Dec - 20 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6053670&startDate=2025-12-19&endDate=2025-12-20&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [20 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6053670&startDate=2025-12-20&endDate=2025-12-21&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [19 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6053670&startDate=2025-12-19&endDate=2025-12-21&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6053670&startDate=2025-12-26&endDate=2025-12-28&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) No exact matches found, but these alternatives could be just right ## Recommended hotels in Santa Cruz Island ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/43000000/42340000/42331800/42331770/71908e9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/43000000/42340000/42331800/42331770/6195dc04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room | In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/43000000/42340000/42331800/42331770/13a6f8c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/43000000/42340000/42331800/42331770/b1e13abb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel La Isla [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Hotel-La-Isla.h42331770.Hotel-Information) Puerto Ayora 9.6/10 Exceptional (64) "Really great stay. Comfortable, coffee/tea on hand anytime, really good breakfast, extremely friendly staff. My review is only “Good” and not “Excellent” because I had a pair of expensive shorts go missing. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Travis Wade [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Hotel-La-Isla.h42331770.Hotel-Information) ![Jetted bathtub](https://images.trvl-media.com/lodging/10000000/9700000/9690700/9690626/b440b32f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/10000000/9700000/9690700/9690626/e523fc0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9700000/9690700/9690626/bb93ee14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/10000000/9700000/9690700/9690626/d6476f6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Fiesta [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Hotel-Fiesta.h9690626.Hotel-Information) Puerto Ayora 9.0/10 Wonderful (380) "Staff was efficient room was clean " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jonathan £116 21 Dec - 22 Dec [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Hotel-Fiesta.h9690626.Hotel-Information) ![Family Suite | Balcony view](https://images.trvl-media.com/lodging/42000000/41950000/41941800/41941787/e7fb3ff1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite | In-room safe, iron/ironing board, bed sheets](https://images.trvl-media.com/lodging/42000000/41950000/41941800/41941787/64ef628d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/42000000/41950000/41941800/41941787/571b5e3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/42000000/41950000/41941800/41941787/75c5fe9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Posada del Mar [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Posada-Del-Mar.h41941787.Hotel-Information) Puerto Ayora 9.8/10 Exceptional (213) "Well maintained property, front staff was very kind and helpful, and the restaurants beside it were incredible." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Bianca £61 20 Dec - 21 Dec [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Posada-Del-Mar.h41941787.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/39000000/38820000/38819900/38819899/f1f7ec0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38820000/38819900/38819899/9c613ed1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38820000/38819900/38819899/4dcb74cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/39000000/38820000/38819900/38819899/c2bf4bc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mainao [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Mainao.h38819899.Hotel-Information) Puerto Ayora 9.6/10 Exceptional (34) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pavel [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Mainao.h38819899.Hotel-Information) ![Yoga](https://images.trvl-media.com/lodging/17000000/16540000/16533100/16533011/2b4d383a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/17000000/16540000/16533100/16533011/41afced2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/17000000/16540000/16533100/16533011/b43ce12e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Yoga](https://images.trvl-media.com/lodging/17000000/16540000/16533100/16533011/8b1cbc8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Semilla Verde Boutique Hotel [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Semilla-Verde-Boutique-Hotel.h16533011.Hotel-Information) Bella Vista 9.8/10 Exceptional (61) "We got to see giant turtles on the hotel grounds. Staff was very pleasant and made our stay excellent." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Marc-André £166 7 Jan - 8 Jan 2026 [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Semilla-Verde-Boutique-Hotel.h16533011.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/7e3fbe48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/d088e7ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room | In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/b5627025.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room | Bathroom | Shower, free toiletries, hair dryer, slippers](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/e94fe441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Capitan Max B&B [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Capitan-Max-BB.h14716616.Hotel-Information) Puerto Ayora 9.8/10 Exceptional (197) "Good location and the staff was friendly and nice. The room was clean and quiet. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) thuy [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Capitan-Max-BB.h14716616.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/11000000/10090000/10087200/10087137/08eca00e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/11000000/10090000/10087200/10087137/507bf9e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10090000/10087200/10087137/7d701bfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/11000000/10090000/10087200/10087137/3d686917.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Ninfa [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Hotel-Ninfa.h10087137.Hotel-Information) Puerto Ayora 8.4/10 Very good (217) "Great, clean, and convenient place. Good location close to docks. Walkable to the Main Street. Hotel rooms clean with good service and breakfast. We stayed here two seperate times during Galapagos and would stay again. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Aly [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Hotel-Ninfa.h10087137.Hotel-Information) ![Water view](https://images.trvl-media.com/lodging/15000000/14850000/14842500/14842408/e0f99a26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/15000000/14850000/14842500/14842408/bb82add7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/15000000/14850000/14842500/14842408/9f35d995.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Regional cuisine ](https://images.trvl-media.com/lodging/15000000/14850000/14842500/14842408/d668ff9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Twin Hotel Galapagos [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Twin-Hotel-Galapagos-By-Rotamundos.h14842408.Hotel-Information) Bella Vista 8.4/10 Very good (44) "This hotle is fantastic lovely people that work here Very helpful with booking tours ect . To rooms are so fantastic, comfortable bed can’t get any better and good breakfast." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Chelsea £74 1 Jan - 2 Jan 2026 [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Twin-Hotel-Galapagos-By-Rotamundos.h14842408.Hotel-Information) ![Garden view](https://images.trvl-media.com/lodging/12000000/11700000/11698100/11698055/6897639d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/12000000/11700000/11698100/11698055/bdea3bf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11700000/11698100/11698055/864dda2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/12000000/11700000/11698100/11698055/8c80acd8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Galapagos Dreams [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-GALAPAGOS-DREAMS.h11698055.Hotel-Information) Puerto Ayora 8.8/10 Excellent (123) "We stayed for 4 days was very good, the breakfast was delicious and also we booked the activities with them, everything was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) esperanza £64 21 Dec - 22 Dec [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-GALAPAGOS-DREAMS.h11698055.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11060000/11050700/11050675/48760e17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room | In-room safe, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/12000000/11060000/11050700/11050675/04070a8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/12000000/11060000/11050700/11050675/738131a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite, 2 Bedrooms, Kitchenette, Ground Floor | Living area | LCD TV](https://images.trvl-media.com/lodging/12000000/11060000/11050700/11050675/57abfab1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Palace Galapagos [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Hotel-Palace-Galapagos.h11050675.Hotel-Information) Puerto Ayora 9.8/10 Exceptional (100) "Great little family run hotel. 5 blocks from the main tourist area. Couldn't fault it! " ![Ireland](https://a.travel-assets.com/egds/marks/flags/ie.svg) Suzy £61 23 Dec - 24 Dec [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Hotel-Palace-Galapagos.h11050675.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-02&endDate=2026-01-03®ionId=6053670&adults=2&specialized_stays_group_explore=boutique_property&sort=RECOMMENDED&openPlayBack=true) ## Top Santa Cruz Island Hotel Reviews ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - [1 Star Hotels in Santa Fe Island ](https://www.expedia.co.uk/1Star-Santa-Fe-Island-Hotels.s10-0-d6336630.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Santa Fe Island ](https://www.expedia.co.uk/2Star-Santa-Fe-Island-Hotels.s20-0-d6336630.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Santa Fe Island ](https://www.expedia.co.uk/3Star-Santa-Fe-Island-Hotels.s30-0-d6336630.Travel-Guide-Filter-Hotels) - [4 Star Hotels in North Seymour Island ](https://www.expedia.co.uk/4Star-North-Seymour-Island-Hotels.s40-0-d6336659.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Santa Fe Island ](https://www.expedia.co.uk/4Star-Santa-Fe-Island-Hotels.s40-0-d6336630.Travel-Guide-Filter-Hotels) - [5 Star Hotels in North Seymour Island ](https://www.expedia.co.uk/5Star-North-Seymour-Island-Hotels.s50-0-d6336659.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Santa Fe Island ](https://www.expedia.co.uk/5Star-Santa-Fe-Island-Hotels.s50-0-d6336630.Travel-Guide-Filter-Hotels) - [Baltra Hotels ](https://www.expedia.co.uk/Baltra-Hotels.d6223000.Travel-Guide-Hotels) - [Bartolome Island Hotels ](https://www.expedia.co.uk/Bartolome-Island-Hotels.d6336382.Travel-Guide-Hotels) - [Bellavista Hotels ](https://www.expedia.co.uk/Bellavista-Hotels.d6342722.Travel-Guide-Hotels) - [Hotels near Charles Darwin Research Station ](https://www.expedia.co.uk/Charles-Darwin-Research-Station-Hotels.0-l6171312-0.Travel-Guide-Filter-Hotels) - [Beach Resorts & in Galápagos ](https://www.expedia.co.uk/Destinations-In-Galapagos-Beach-Hotels.0-0-d1371-tBeachHotels.Hotel-Filter-Destinations) - [Cheap Hotels in Galápagos ](https://www.expedia.co.uk/Destinations-In-Galapagos-Budget-Hotels.0-0-d1371-tBudgetHotels.Hotel-Filter-Destinations) - 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