Find Spa Hotels in Santa Ana, CA

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Save instantly and earn perks with One Key
  • Be picky

    Search almost a million properties worldwide

Check availability on Santa Ana Spa Hotels

Our top choices for Santa Ana hotels with a spa

Ayres Hotel & Spa Mission Viejo – Lake Forest

Ayres Hotel & Spa Mission Viejo – Lake Forest
3.5 star property
Mission Viejo
9.2 out of 10, Wonderful, (1,086 reviews)
  • cleanliness
    Revitalise with luxurious spa treatments, mountain views, and a serene outdoor pool at this relaxing retreat.
The price is £82
includes taxes & fees
11 May - 12 May
Ayres Hotel & Spa Mission Viejo – Lake Forest

Holiday Inn Diamond Bar - Pomona by IHG

Holiday Inn Diamond Bar - Pomona by IHG
3.0 star property
Diamond Bar
9.0 out of 10, Wonderful, (1,015 reviews)
  • cleanliness
    Indulge in a full-service spa experience at this Diamond Bar hotel featuring a hot tub, outdoor pool, and rejuvenating wellness options.
The price is £107
includes taxes & fees
3 May - 4 May
Holiday Inn Diamond Bar - Pomona by IHG

Laguna Cliffs Marriott Resort and Spa

Laguna Cliffs Marriott Resort and Spa
4.0 star property
Lantern District
8.8 out of 10, Excellent, (1,002 reviews)
  • cleanliness
    Serene oceanside retreat with 9 treatment rooms offering massages and facials, plus dual pools and hot tubs for a complete wellness escape.
The price is £241
includes taxes & fees
19 Apr - 20 Apr
Laguna Cliffs Marriott Resort and Spa

Renaissance ClubSport Aliso Viejo Laguna Beach Hotel

Renaissance ClubSport Aliso Viejo Laguna Beach Hotel
3.5 star property
Aliso Viejo
9.0 out of 10, Wonderful, (952 reviews)
  • cleanliness
    Escape to a full-service spa sanctuary with 9 treatment rooms and 3 outdoor pools at this tranquil Laguna Beach retreat.
The price is £175
includes taxes & fees
26 Apr - 27 Apr
Renaissance ClubSport Aliso Viejo Laguna Beach Hotel

Best Western Plus Newport Mesa Inn

Best Western Plus Newport Mesa Inn
3.0 star property
Costa Mesa
8.8 out of 10, Excellent, (1,076 reviews)
  • cleanliness
    Experience a rejuvenating escape at this hotel with a full-service spa, outdoor pool, and hot tub for a blissful wellness retreat.
The price is £108
includes taxes & fees
26 Apr - 27 Apr
Best Western Plus Newport Mesa Inn

Hyatt Regency Huntington Beach Resort and Spa

Hyatt Regency Huntington Beach Resort and Spa
4.0 star property
Huntington Beach
9.4 out of 10, Exceptional, (1,016 reviews)
  • cleanliness
    Coastal retreat with 17 spa treatment rooms and 5 hot tubs awaits, offering massages and aromatherapy in Mediterranean elegance.
The price is £274
includes taxes & fees
22 Apr - 23 Apr
Hyatt Regency Huntington Beach Resort and Spa

The Waterfront Beach Resort, A Hilton Hotel

The Waterfront Beach Resort, A Hilton Hotel
4.0 star property
Huntington Beach
9.2 out of 10, Wonderful, (1,019 reviews)
  • cleanliness
    Rejuvenate at this beachfront resort with 9 treatment rooms, couples massages, and outdoor spa areas overlooking the ocean.
The price is £250
includes taxes & fees
19 Apr - 20 Apr
The Waterfront Beach Resort, A Hilton Hotel

Pacific Palms Resort

Pacific Palms Resort
4.0 star property
City of Industry
8.8 out of 10, Excellent, (1,158 reviews)
  • cleanliness
    Pamper your senses at this mountain resort spa offering rejuvenating massages and scenic views from outdoor wellness areas.
The price is £183
includes taxes & fees
7 May - 8 May
Pacific Palms Resort

The Ritz-Carlton, Laguna Niguel

The Ritz-Carlton, Laguna Niguel
5.0 star property
Monarch Beach
9.0 out of 10, Wonderful, (36 reviews)
  • cleanliness
    Oceanfront retreat with 5-star spa services offers holistic relaxation in luxurious beachfront setting.
The price is £690
includes taxes & fees
11 May - 12 May
The Ritz-Carlton, Laguna Niguel

Balboa Bay Resort

Balboa Bay Resort
4.5 star property
Newport Heights
9.0 out of 10, Wonderful, (1,002 reviews)
  • cleanliness
    Rejuvenate at this waterfront resort with a full-service spa offering couples treatments, sauna sessions, and therapeutic body wraps.
The price is £281
includes taxes & fees
19 Apr - 20 Apr
Balboa Bay Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Choose what matters most at spa hotels in Santa Ana

Find out more about Santa Ana

Top Santa Ana attractions for a relaxing vacation

Santa Ana, California, offers a wealth of experiences for travellers seeking relaxation and rejuvenation at spa hotels. Start your journey at the stunning Bowers Museum, where you can immerse yourself in the rich art and cultural exhibits, making it a perfect prelude to a pampering session. After a day of exploration, indulge in a revitalising massage at one of the local spa hotels, such as the iconic Hilton Orange County/Costa Mesa, which features luxurious spa services that cater to your every need. For a family-friendly outing, visit the Santa Ana Zoo, where children can learn about wildlife while parents can unwind in the serene surroundings. The downtown area is vibrant with charming boutiques and gourmet eateries, ideal for leisurely strolls after a day at the spa. Finally, don’t miss the chance to explore the nearby beaches, only a short drive away, where you can bask in the sun and breathe in the fresh ocean air. Staying in the heart of Santa Ana allows easy access to these attractions while ensuring a comfortable and luxurious hotel experience that meets your high expectations.

Find the best hotels & resorts with spas in Santa Ana

For those seeking relaxation and rejuvenation in Santa Ana, California, these hotels offer excellent spa amenities to ensure a refreshing getaway.

Best Western Plus Orange County Airport North

  • Why it's great for tailored spa getaway: The Best Western Plus Orange County Airport North is an ideal choice for travellers looking to unwind with accessible spa amenities. With a solid guest review rating of 8.6, this hotel combines comfort and convenience, featuring a relaxing hot tub and an outdoor pool for guests to enjoy after a day of exploration.
  • Other amenities: Additional features include free breakfast options, a fitness centre for those wanting to stay active, and daily housekeeping to ensure a comfortable stay. Guests can also take advantage of the garden area, offer extended duration parking, and have access to nearby golf courses. The hotel also boasts accessible parking and concierge services to assist with your travel needs.
  • Nearby attractions: South Coast Plaza - 4.9 km, Santa Ana Zoo - 4.4 km, Segerstrom Center for the Arts - 5.2 km

Comfort Inn & Suites Orange County John Wayne Airport

  • Why it's great for tailored spa getaway: The Comfort Inn & Suites Orange County John Wayne Airport provides a welcoming atmosphere for travellers seeking spa accessibility. Rated 8.0 by guests, this hotel offers a delightful hot tub and an outdoor pool, perfect for relaxation after a busy day in Santa Ana.
  • Other amenities: Guests can enjoy complimentary breakfast options, an airport shuttle service, and a fitness centre to maintain their wellness routines. The hotel features secure parking, traditional design elements, and poolside sun loungers for leisure. For added convenience, there’s also a microwave in each room, daily housekeeping, and nearby attractions including museums to explore.
  • Nearby attractions: South Coast Plaza - 5 km, Santa Ana Zoo - 4.2 km, Segerstrom Center for the Arts - 5.3 km

Top Santa Ana Hotel Reviews

Frequently asked questions

How much does a spa hotel in Santa Ana cost?
Enjoy staying in a spa hotel in Santa Ana, with plenty of hotels from £82 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, and may vary depending on the location, season, and hotel amenities. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a trip during the weekend or around public holidays.
Is it cheaper to book a spa hotel in Santa Ana with flights as part of a package deal?
Booking a hotel and flight package on Expedia can be cheaper than booking flights and hotels separately. Bundling can lead to significant savings, especially for international travel or when booking well in advance. However, savings vary depending on factors like destination, travel dates, and availability, so it's wise to compare options. With access to over 300,000 hotels worldwide, Expedia makes it easy to build the perfect holiday package.
Are there any unique spa experiences available in Santa Ana?
Yes, Santa Ana offers several unique spa experiences that combine luxury, relaxation, and specialized treatments.

Montanya Spa, an Asian-themed day spa near the Bowers Museum, is known for its tranquil, nature-inspired setting. It features a meditation room, sauna, steam room, and an outdoor tea garden, offering personalised massages and facials followed by a tea service and a relaxing experience with heating pads and blankets.

House of Aesthetics Med Spa, located near Santa Ana, provides advanced aesthetic treatments such as laser therapies, injectables, and revitalising facials. This med spa focuses on a personalised approach with state-of-the-art technology in a tranquil urban setting.

Irvine Spa, while technically in Irvine, is close to Santa Ana and offers a holistic spa experience with unique features like a Salt Room with organic Himalayan salt for skin and respiratory benefits, a Forest Room designed to promote mental clarity, and an Ice Room for muscle recovery and circulation boost.
How can I save on a spa hotel in Santa Ana with Expedia?
Members always get our best prices. Find our best Santa Ana spa hotel deals by joining One Key™, Expedia's free travel rewards program. As a member, you can unlock instant savings and member perks when you're logged in to your account. For a quick weekend retreat, discover last-minute offers.
Can I cancel my spa hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use Expedia's "Fully refundable property" filter during your search to find the right spa hotel in Santa Ana for you.

Explore a world of travel with Expedia