San Isidro Holidays from £1,270
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Your San Isidro Holiday
Say goodbye to the hassle of planning and hello to a San Isidro holiday package. With the finer details organised before you take off, you can focus on discovering every inch of this city, starting with Cartagena Walled City, which is great for views, dining and bars and pubs. If a sightseeing tour is part of the programme during your trip to San Isidro, stop by leading attractions like San Felipe de Barajas Castle, San Pedro Claver Church and Convent and Jaime Moron Stadium. Whoever you're heading away with and whatever you want to spend, your ultimate San Isidro holiday is just a few clicks away with Expedia.
Price found within the past 48 hours. Click for updated prices.
Ananda Hotel Boutique
Cartagena Walled City
£1,318
per person
12 Oct - 14 Oct
found 23 hours ago
Additional charges may apply
Return flight included
London (LON) to Cartagena (CTG)
9.2/10 Wonderful! (467 reviews)
Clean and confortable rooms, amazing staff, very quiet and relaxing. The highlight of our trip
Reviewed on 28 Aug 2026
Isla Corona
£1,664
per person
12 Oct - 14 Oct
found 23 hours ago
Additional charges may apply
Return flight included
London (LON) to Cartagena (CTG)
9.6/10 Exceptional! (29 reviews)
Samuel was the best service staff we have ever had. He made an effort to learn English words with us while also teaching us Spanish. He definitely made the trip even better. As for the island, it was incredible. The boat ride there and back was 1000x better than a day trip boat I took a day prior with another company. It’s breezy at night on the island which helps keeps the mosquitos away. Would definitely recommend staying at least 2 nights to be able to fully enjoy the island :)
Reviewed on 2 Jul 2026
Where to stay in San Isidro
Find the best San Isidro areas and neighborhoods for the activities you enjoy most. Learn more about San Isidro
Cartagena Walled City
3 out of top 10 points of interest in this area
Cartagena Walled City is known for its abundant dining options, and you can plan a trip to Clock Tower and Bolivar Square while you're in town.
Bocagrande
1 out of top 10 points of interest in this area
Bocagrande is known for its stunning beaches, and with sights like Rio Cartagena Casino and Plaza Bocagrande Commercial Center, you won't get bored spending a day wandering around this part of Cartagena.
Getsemani
Travellers come to Getsemani for its abundant dining options, and you can see top attractions like Plaza de la Trinidad and Los Pegasos Dock while you're in town.
Cartagena Centro
Unique features of Cartagena Centro include the museums and historical sites. Make a stop by Plaza Santo Domingo or Bolivar Square while you're exploring the area.
San Diego
San Diego is popular for its abundant dining options, and if you're looking for more to see and do, you might think about a trip to Las Bovedas or Walls of Cartagena.
Top hotels in San Isidro
Hotel Caribe by Faranda Grand, a member of Radisson Individuals
Carrera 1a No 2-87 Cartagena Bolivar
Fully refundableReserve now, pay when you stay
£176
30 Sept - 1 Oct
additional charges may apply
Sofitel Barú Cartagena
KM 7 Sector, Porto Nao Cartagena Bolívar
Fully refundableReserve now, pay when you stay
£259
21 Sept - 22 Sept
additional charges may apply
9.4/10 Exceptional! (805 reviews)
"Best experience!!! We love it!!!"
Reviewed on 10 Sept 2026
Faranda Collection Cartagena, a member of Radisson Individuals
Anillo vial Carrera 9 #22-620 Cartagena Bolívar
Fully refundableReserve now, pay when you stay
£123
13 Sept - 14 Sept
additional charges may apply
9.4/10 Exceptional! (142 reviews)
"Great hotel, had an issue with the first room as the door would not lock. We were issued a new room after 30 minutes of waiting."
Reviewed on 9 Sept 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a San Isidro travel package cost?
Custom build your San Isidro travel package from a low £1,270. Pick from any combination of rental cars, flights and hotels to create the escape you've long been dreaming about. Remember to add on a few activities!
If I'm not able to travel, can I cancel my San Isidro travel package?
Plans can change unexpectedly, so yes. You may be able to cancel and rebook your San Isidro travel package at no cost within 24 hours of booking. For bookings older than that, you can still make changes, but your car rental company, airline or hotel may charge additional fees. Need more information? Look up our Customer Service Portal. We're here to help make sure your getaway goes off without a hitch.
How do I get a cheap travel package to San Isidro?
One of the easiest ways to save money (and time) is to bundle your bookings with Expedia. Hotels, rental cars, flights and activities — we've got everything you need. Select a combination that suits your style and see your savings grow. We know a travel package is never a one-size-fits-all. That's why Expedia offers over 550 airlines and 1,000,000 hotels from all over the world, which lets you customize your San Isidro holiday.
Does Expedia offer Book Now, Pay Later San Isidro holidays?
Your bank balance shouldn't stop you from taking a holiday, so Expedia has worked out a solution to help. Now that we've joined forces with online lender Klarna, it's easier than ever to book an incredible getaway without draining your savings. Klarna offers flexible payment options at checkout that take the worry out of budgeting for your trip. Check out these flexible payment options:
- Pay monthly holidays: Klarna has easy monthly payment plans that work for all budgets, so you can lock in that well-earned holiday now.
- Pay in instalments holidays: Like the idea of paying for your holiday in multiple transactions? Then select this Book Now, Pay Later option from Klarna.
- Low deposit holidays: When you want to jump on an incredible deal but your budget doesn't quite cover it yet, Klarna's low deposit holiday plan will help you lock in your getaway.
Where should I stay in San Isidro?
Most travellers who visit San Isidro put both San Felipe de Barajas Castle and San Fernando Fort on their bucket lists. Why not go for a hotel within walking distance of these fantastic attractions?
What are the top hotels in San Isidro?
Hilton Cartagena and Intercontinental Cartagena De Indias are two of the most popular properties in San Isidro. Why not check out the amenities and facilities at each and then make a decision?
How far in advance should I book my San Isidro holiday?
Earlier is always better. Air carriers generally release flight tickets nearly 12 months prior to departure, and this is an excellent opportunity to land some rock-bottom prices. Boss just told you to use up your holiday time next week? No problem! Expedia are never short on fantastic bargains to send you off on the getaway of your dreams, at a price you can afford.
What does an Expedia San Isidro travel package include?
It comes down to what you're after. If you're travelling solo, you might decide to combine hotels and flights. Taking the whole crew to San Isidro? A travel package including rental cars, flights and hotels might suit you better. Expedia gives you the flexibility to build your own travel package.
What should I know before booking a San Isidro travel package?
You can save a tidy sum by combining your hotels, airfares and rental cars. Once you've created your package, you can add on activities or tours. Your next unforgettable holiday is only a few clicks away.
Can I choose my airline with a San Isidro Expedia travel package?
Definitely. Expedia has over 550 partner airlines to select from worldwide. With so many choices, finding the right carrier to whisk you away to San Isidro shouldn't be hard.
Things to do
Cartagena's Rosario Islands 5-Site Boat Tour with Lunch & Snorkel
£55
per adult
84% of travellers recommend
Cartagena, CO: Sunset Skyline Bay Tour on a Pirate Boat + Drinks
£37
per adult
86% of travellers recommend
Cartagena 5 Island Hop Tour: Lunch, Snorkel, Beach Clubs, & More
£51
per adult
84% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.