San Isidro Holidays

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    Save up to £750 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Packages with flights are ATOL protected

Your San Isidro Holiday

Say goodbye to the hassle of planning and hello to a San Isidro holiday package. With the finer details organised before you take off, you can focus on discovering every inch of this city, starting with Cartagena Walled City, which is great for views, dining and bars and pubs. If a sightseeing tour is part of the programme during your trip to San Isidro, stop by leading attractions like San Felipe de Barajas Castle, San Pedro Claver Church and Convent and Jaime Moron Stadium. Whoever you're heading away with and whatever you want to spend, your ultimate San Isidro holiday is just a few clicks away with Expedia.

The Latest San Isidro Holiday Packages

Price found within the past 48 hours. Click for updated prices.
  • Aug 26 - Sep 5

    Delirio + Flight

    Cartagena Walled City
    10 nights
    3.5 star property
    8.6/10 - Excellent (477 reviews)
    "the staff is exepcional"
    Reviewed March 29, 2026
    Return Newcastle-upon-Tyne (NCL) - Cartagena (CTG)
    NCL - CTG2 stops CTG - NCL2 stops
    £2,483
    £1,746
    per traveller
    found 16 hours agoAdditional charges may apply
    Delirio
  • Jul 18 - Jul 25

    Isla Corona + Flight

    Rosario Islands
    7 nights
    4.0 star property
    9.6/10 - Exceptional (23 reviews)
    "Excelente lugar lo único malo fue el tiempo que decidimos quedarnos te quedas con ganas de más tiempo ahí la atención el personal súper atento y al pendiente el lugar está hermoso excelente para relajamiento y si te gusta la corona como a mí este es el paraíso súper recomendado el cuarto otro paraíso aparte súper limpio con todo lo que necesitas y más"
    Reviewed May 28, 2026
    Return London (LHR) - Cartagena (CTG)
    LHR - CTG2 stops CTG - LHR2 stops
    Save 100% on your flight
    £4,382
    £2,395
    per traveller
    found 19 hours agoAdditional charges may apply
    Isla Corona
  • Aug 26 - Sep 5

    Cinco Quintas Hotel Boutique + Flight

    Cartagena Walled City
    10 nights
    4.0 star property
    9.4/10 - Exceptional (299 reviews)
    "Very friendly staff always ready to help, the room and overall hotel was very clean. The only thing is the pool is very small and there aren’t any amenities like a gym in the property. However, I highly recommend it and I will book again."
    Reviewed May 31, 2026
    Return Newcastle-upon-Tyne (NCL) - Cartagena (CTG)
    NCL - CTG2 stops CTG - NCL2 stops
    £3,186
    £2,093
    per traveller
    found 16 hours agoAdditional charges may apply
    Cinco Quintas Hotel Boutique
  • Aug 26 - Sep 5

    Bastión Luxury Hotel + Flight

    Cartagena Walled City
    10 nights
    4.5 star property
    9.6/10 - Exceptional (1,011 reviews)
    "The perfect hotel to stay over inside the walls of the historical old part of Cartagena. A hidden gem the Bastion hotel, with spacious clean rooms, good and healthy breakfast buffet, friendly staff and a beautiful rooftop with swimming pool, and the hotel offers 24/7 à la carte service. Highly recommend to stay at this great property."
    Reviewed June 10, 2026
    Return Newcastle-upon-Tyne (NCL) - Cartagena (CTG)
    NCL - CTG2 stops CTG - NCL2 stops
    £3,015
    £2,047
    per traveller
    found 16 hours agoAdditional charges may apply
    Bastión Luxury Hotel
  • Jul 18 - Jul 25

    Hotel Boutique Casa del Coliseo + Flight

    Cartagena Walled City
    7 nights
    4.5 star property
    9.4/10 - Exceptional (320 reviews)
    Return London (LHR) - Cartagena (CTG)
    LHR - CTG2 stops CTG - LHR2 stops
    £2,625
    £1,816
    per traveller
    found 19 hours agoAdditional charges may apply
    Hotel Boutique Casa del Coliseo

Where to stay in San Isidro

Find the best San Isidro areas and neighborhoods for the activities you enjoy most. Learn more about San Isidro

Top hotels in San Isidro

GHL Corales de Indias

GHL Corales de Indias

4 out of 5
Carrera 1 No. 62-198 Cartagena Bolivar
Fully refundableReserve now, pay when you stay
The price is £95 per night from 23 Jun to 24 Jun
£95
23 Jun - 24 Jun
additional charges may apply
8.2/10 Very Good! (1,002 reviews)
"Servicio 10/10"

Reviewed on 30 May 2026

GHL Corales de Indias
OZ Hotel Collection

OZ Hotel Collection

3.5 out of 5
6-164 Carrera 2 Cartagena
Fully refundableReserve now, pay when you stay
The price is £67 per night from 30 Jun to 1 Jul
£67
30 Jun - 1 Jul
additional charges may apply
9.6/10 Exceptional! (524 reviews)
"Excellent"

Reviewed on 10 Jun 2026

OZ Hotel Collection
Hotel Casa San Agustin

Hotel Casa San Agustin

4.5 out of 5
Centro Calle de la Universidad No.36-44 Cartagena Bolivar
Fully refundableReserve now, pay when you stay
The price is £406 per night from 3 Jul to 4 Jul
£406
3 Jul - 4 Jul
additional charges may apply
9.8/10 Exceptional! (488 reviews)
"Beautiful property. Exquisite service. Kind and available staff. Delicious breakfast."

Reviewed on 4 Jun 2026

Hotel Casa San Agustin
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a San Isidro travel package cost?
Custom build your San Isidro travel package from a low . Pick from any combination of rental cars, flights and hotels to create the escape you've long been dreaming about. Remember to add on a few activities!
If I'm not able to travel, can I cancel my San Isidro travel package?
Plans can change unexpectedly, so yes. You may be able to cancel and rebook your San Isidro travel package at no cost within 24 hours of booking. For bookings older than that, you can still make changes, but your car rental company, airline or hotel may charge additional fees. Need more information? Look up our Customer Service Portal. We're here to help make sure your getaway goes off without a hitch.
How do I get a cheap travel package to San Isidro?
One of the easiest ways to save money (and time) is to bundle your bookings with Expedia. Hotels, rental cars, flights and activities — we've got everything you need. Select a combination that suits your style and see your savings grow. We know a travel package is never a one-size-fits-all. That's why Expedia offers over 550 airlines and 1,000,000 hotels from all over the world, which lets you customize your San Isidro holiday.
Does Expedia offer Book Now, Pay Later San Isidro holidays?
Your bank balance shouldn't stop you from taking a holiday, so Expedia has worked out a solution to help. Now that we've joined forces with online lender Klarna, it's easier than ever to book an incredible getaway without draining your savings. Klarna offers flexible payment options at checkout that take the worry out of budgeting for your trip. Check out these flexible payment options:

  • Pay monthly holidays: Klarna has easy monthly payment plans that work for all budgets, so you can lock in that well-earned holiday now.
  • Pay in instalments holidays: Like the idea of paying for your holiday in multiple transactions? Then select this Book Now, Pay Later option from Klarna.
  • Low deposit holidays: When you want to jump on an incredible deal but your budget doesn't quite cover it yet, Klarna's low deposit holiday plan will help you lock in your getaway.

Where should I stay in San Isidro?
Most travellers who visit San Isidro put both San Felipe de Barajas Castle and San Fernando Fort on their bucket lists. Why not go for a hotel within walking distance of these fantastic attractions?
What are the top hotels in San Isidro?
Hilton Cartagena and Intercontinental Cartagena De Indias are two of the most popular properties in San Isidro. Why not check out the amenities and facilities at each and then make a decision?
How far in advance should I book my San Isidro holiday?
Earlier is always better. Air carriers generally release flight tickets nearly 12 months prior to departure, and this is an excellent opportunity to land some rock-bottom prices. Boss just told you to use up your holiday time next week? No problem! Expedia are never short on fantastic bargains to send you off on the getaway of your dreams, at a price you can afford.
What does an Expedia San Isidro travel package include?
It comes down to what you're after. If you're travelling solo, you might decide to combine hotels and flights. Taking the whole crew to San Isidro? A travel package including rental cars, flights and hotels might suit you better. Expedia gives you the flexibility to build your own travel package.
What should I know before booking a San Isidro travel package?
You can save a tidy sum by combining your hotels, airfares and rental cars. Once you've created your package, you can add on activities or tours. Your next unforgettable holiday is only a few clicks away.
Can I choose my airline with a San Isidro Expedia travel package?
Definitely. Expedia has over 550 partner airlines to select from worldwide. With so many choices, finding the right carrier to whisk you away to San Isidro shouldn't be hard.

Popular places to visit

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.