Mission Bay Travel Guide

San Francisco

A coastal cityscape with a large body of water, several ships, and ongoing construction on a prominent red building.
A coastal cityscape with a prominent skyscraper, a large stadium, and a marina with boats.
A cityscape at dusk with a parking lot and buildings.
A large reflective sphere in front of a modern building with a glass facade and a Christmas tree.

Stay near popular Mission Bay attractions

Chase Center

8.8/10 (1,176 reviews)
Catch an event at Chase Center during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its fascinating museums.
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Things to do

California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

£37
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
Go City: San Francisco All-Inclusive Pass with 25+ Attractions

Go City: San Francisco All-Inclusive Pass with 30+ Attractions

£73
per adult
88% of travellers recommend
Go City: San Francisco All-Inclusive Pass with 30+ Attractions
San Francisco City Lights Cruise

California Sunset Cruise (2-hours)

£43
per adult
94% of travellers recommend
California Sunset Cruise (2-hours)
San Francisco SkyStar Wheel - Private Gondolas

San Francisco SkyStar Wheel - Private Gondolas

£14
per adult
82% of travellers recommend
San Francisco SkyStar Wheel - Private Gondolas
San Francisco: One day Yosemite and Giant Sequoia Tour

San Francisco: One day Yosemite and Giant Sequoias Tour

£154
per adult
90% of travellers recommend
San Francisco: One day Yosemite and Giant Sequoias Tour
Aquarium of the Bay General Admission Ticket

San Francisco, Aquarium of the Bay General Admission Ticket

£21
per adult
100% of travellers recommend
San Francisco, Aquarium of the Bay General Admission Ticket
See all activities in San Francisco

Top hotels in Mission Bay

LUMA Hotel San Francisco

LUMA Hotel San Francisco

4 out of 5
100 Channel Street San Francisco CA
The price is £218 per night from 31 Oct to 1 Nov
£218
31 Oct - 1 Nov
includes taxes & fees
Stay at this hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean rooms in their ...
LUMA Hotel San Francisco
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
The price is £135 per night from 25 Oct to 26 Oct
£135
25 Oct - 26 Oct
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the pool and the ...
9/10 Wonderful! (6,365 reviews)
"It was quiet and they gave us a corner room with a nice view."

Reviewed on 3 Oct 2026

Holiday Inn Golden Gateway by IHG
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
The price is £124 per night from 4 Oct to 5 Oct
£124
4 Oct - 5 Oct
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...
Hilton San Francisco Financial District
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
The price is £135 per night from 2 Nov to 3 Nov
£135
2 Nov - 3 Nov
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the ...
9/10 Wonderful! (7,678 reviews)
"Great staff, amazing breakfast with everything you need. Clean and near everything I recommend"

Reviewed on 3 Oct 2026

Hotel Riu Plaza Fisherman's Wharf
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center San Francisco CA
The price is £212 per night from 4 Oct to 5 Oct
£212
4 Oct - 5 Oct
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the ...
Hyatt Regency San Francisco
Hilton San Francisco Union Square

Hilton San Francisco Union Square

4 out of 5
333 O'Farrell St. San Francisco CA
The price is £145 per night from 30 Oct to 31 Oct
£145
30 Oct - 31 Oct
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy 2 bars/lounges, breakfast (surcharge) and a 24-hour health club. Our guests praise the helpful staff ...
Hilton San Francisco Union Square
See all 4,358 properties in Mission Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mission Bay

Find the best Mission Bay areas for the activities you enjoy most.
A pier with a large number of sea lions resting on floating platforms.

Fisherman's Wharf

Travellers love Fisherman's Wharf for its popular shops, and you can see more of San Francisco by jumping on the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop. You might spend time checking out top sights like Pier 39 and San Francisco Bay.

A cityscape with tall buildings, a central plaza with palm trees, and a flag on one of the buildings.

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

A trolley on a street with buildings and a clock tower.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

A cityscape with modern skyscrapers, a central park with pathways, and a few people walking.

South of Market

Gourmet restaurants great entertainment and top sights from Oracle Park to Chase Center – discover South of Market, a destination also famous for its shopping.

A street lined with historic buildings, parked cars, and a clear blue sky.

Nob Hill

Gourmet restaurants Chinatown and top sights from SF Masonic Auditorium to Cable Car Museum – discover Nob Hill, a destination also famous for its shopping.

Mission Bay Travel Guide

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