Mission Bay Travel Guide

San Francisco

A coastal cityscape with a large body of water, several ships, and ongoing construction on a prominent red building.
A coastal cityscape with a prominent skyscraper, a large stadium, and a marina with boats.
A cityscape at dusk with a parking lot and buildings.
A large reflective sphere in front of a modern building with a glass facade and a Christmas tree.

Stay near popular Mission Bay attractions

Chase Center

8.8/10 (1,176 reviews)
Catch an event at Chase Center during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its fascinating museums.
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Things to do

California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

£36
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
San Francisco SkyStar Wheel - Private Gondolas

San Francisco SkyStar Wheel - Private Gondolas

£14
per adult
82% of travellers recommend
San Francisco SkyStar Wheel - Private Gondolas
San Francisco: One day Yosemite and Giant Sequoia Tour

San Francisco: One day Yosemite and Giant Sequoias Tour

£151
per adult
90% of travellers recommend
San Francisco: One day Yosemite and Giant Sequoias Tour
Aquarium of the Bay General Admission Ticket

San Francisco, Aquarium of the Bay General Admission Ticket

£21
per adult
100% of travellers recommend
San Francisco, Aquarium of the Bay General Admission Ticket
de Young Museum General Admission Ticket

de Young Museum General Admission Ticket

£18
per adult
88% of travellers recommend
de Young Museum General Admission Ticket
Golden Gate Bridge at night

San Francisco Night Tour

£35
per adult
78% of travellers recommend
San Francisco Night Tour
See all activities in San Francisco

Top hotels in Mission Bay

LUMA Hotel San Francisco

LUMA Hotel San Francisco

4 out of 5
100 Channel Street San Francisco CA
The price is £187 per night from 20 Sept to 21 Sept
£187
per night
20 Sept - 21 Sept
Stay at this hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean rooms in their ...
9.6/10 Exceptional! (2,595 reviews)
"Parking too expensive"

Reviewed on 10 Sept 2026

LUMA Hotel San Francisco
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
The price is £132 per night from 20 Sept to 21 Sept
£132
per night
20 Sept - 21 Sept
Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the pool and the ...
9/10 Wonderful! (6,280 reviews)
"Staff"

Reviewed on 11 Sept 2026

Holiday Inn Golden Gateway by IHG
Hilton San Francisco Union Square

Hilton San Francisco Union Square

4 out of 5
333 O'Farrell St. San Francisco CA
The price is £152 per night from 2 Oct to 3 Oct
£152
per night
2 Oct - 3 Oct
Stay at this business-friendly hotel in San Francisco. Enjoy 2 bars/lounges, breakfast (surcharge) and a 24-hour health club. Our guests praise the helpful staff ...
Hilton San Francisco Union Square
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
The price is £175 per night from 18 Sept to 19 Sept
£175
per night
18 Sept - 19 Sept
Stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the ...
9/10 Wonderful! (7,665 reviews)
"Excellent location! Parking available on premise. Amazing breakfast. Room nice, spacious and clean. Staff super helpful. Wonderful experience overall."

Reviewed on 11 Sept 2026

Hotel Riu Plaza Fisherman's Wharf
The Pickwick Hotel

The Pickwick Hotel

3.5 out of 5
85 5th St San Francisco CA
The price is £86 per night from 4 Oct to 5 Oct
£86
per night
4 Oct - 5 Oct
Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and a fitness centre. Our guests praise the helpful staff and ...
7.8/10 Good! (1,523 reviews)
"Shower should have guard rails/handles"

Reviewed on 10 Sept 2026

The Pickwick Hotel
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
The price is £106 per night from 20 Sept to 21 Sept
£106
per night
20 Sept - 21 Sept
Stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...
8.8/10 Excellent! (3,199 reviews)
"Clean room"

Reviewed on 11 Sept 2026

Hilton San Francisco Financial District
See all 4,415 properties in Mission Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mission Bay

Find the best Mission Bay areas for the activities you enjoy most.
A street with shops, including a crystal shop and a crepes cafe.

Fisherman's Wharf

Travellers love Fisherman's Wharf for its popular shops, and you can see more of San Francisco by jumping on the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop. You might spend time checking out top sights like Pier 39 and San Francisco Bay.

A cityscape with tall buildings, a central plaza with palm trees, and a flag on one of the buildings.

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

A trolley on a street with buildings and a clock tower.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

A cityscape with modern skyscrapers, a central park with pathways, and a few people walking.

South of Market

Gourmet restaurants great entertainment and top sights from Oracle Park to San Francisco Bay – discover South of Market, a destination also famous for its shopping.

A street lined with historic buildings, parked cars, and a clear blue sky.

Nob Hill

Gourmet restaurants Chinatown and top sights from SF Masonic Auditorium to Cable Car Museum – discover Nob Hill, a destination also famous for its shopping.

Mission Bay Travel Guide

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