Mission Bay Holidays from £1,123

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Your Mission Bay Holiday

Organising your next adventure just got easier with a holiday package to Mission Bay. Enjoy all this neighbourhood has to offer while creating beautiful memories that'll stay with you for years. When it's time to explore the sights, you'll find a lot of big-name attractions nearby including Pier 39, Lombard Street and Oracle Park. Tick off one, two or all during your trip to Mission Bay. No matter your travel plans or budget, booking a perfect Mission Bay holiday is easy with Expedia.

Price found within the past 48 hours. Click for updated prices.
Hampton Inn San Francisco Downtown/Convention Center

Hampton Inn San Francisco Downtown/Convention Center

3 out of 5
Downtown San Francisco
Price was £2,627, price is now £1,123 per person
£1,123
per person
17 May - 22 May
found 1 day ago
Return flight included
London (LHR) to San Francisco (SFO)
7.8/10 Good! (1,254 reviews)
I would have liked to be placed a room with a view.. breakfast was great..

Reviewed on 8 Apr 2026

Treehouse Hotel Silicon Valley

Treehouse Hotel Silicon Valley

5 out of 5
Save 100% on your flight
Price was £4,352, price is now £2,734 per person
£2,734
per person
18 May - 25 May
found 1 day ago
Return flight included
London (LHR) to San Francisco (SFO)
9.8/10 Exceptional! (84 reviews)
We had a great time celebrating my husband's birthday there. We thought we had to venture out to grab meals around the area, but the food there were great. And we just have a relaxing time there.

Reviewed on 5 Apr 2026

1 Hotel San Francisco

1 Hotel San Francisco

5 out of 5
Downtown San Francisco
Save 100% on your flight
Price was £2,289, price is now £1,451 per person
£1,451
per person
30 Jun - 5 Jul
found 1 day ago
Return flight included
London (LHR) to San Francisco (SFO)
9.2/10 Wonderful! (525 reviews)
Amazing ambiance. Great staff and Daily Breakfast.

Reviewed on 10 Apr 2026

The Huntington Hotel

The Huntington Hotel

5 out of 5
Downtown San Francisco
Save 100% on your flight
Price was £3,695, price is now £2,398 per person
£2,398
per person
15 Jun - 20 Jun
found 1 day ago
Return flight included
London (LHR) to San Francisco (SFO)
10/10 Exceptional! (2 reviews)
After a long hiatus, the Hunington is back, and thanks to the owners and Ken Faulk, the property is as it was in 1980 but with the addition of a lobby bar and understated elegance in the all new rooms and interiors. The Big Four looks like it was never touched. I never imagined an old hotel that everyone loved could have been brought back so elegantly.

Reviewed on 27 Mar 2026

Where to stay in Mission Bay

Find the best Mission Bay areas and neighborhoods for the activities you enjoy most. Learn more about Mission Bay
Fisherman's Wharf

Fisherman's Wharf

1 out of top 10 points of interest in this area
5/5(4 area reviews)

This waterfront neighborhood dates back to the gold rush era and is a hub for tourist activities, sea lions and seafood restaurants.

Find hotels in Fisherman's Wharf

Top hotels in Mission Bay

LUMA Hotel San Francisco

LUMA Hotel San Francisco

4 out of 5
100 Channel Street San Francisco CA
Fully refundableReserve now, pay when you stay
The price is £172 per night from 18 Apr to 19 Apr
£172
18 Apr - 19 Apr
includes taxes & fees
9.6/10 Exceptional! (2,459 reviews)
Yes

Reviewed on 13 Apr 2026

LUMA Hotel San Francisco
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
Fully refundableReserve now, pay when you stay
The price is £115 per night from 19 Apr to 20 Apr
£115
19 Apr - 20 Apr
includes taxes & fees
9/10 Wonderful! (5,561 reviews)
Breakfast is over priced for simple breakfast that is served cold. No microwaves in rooms was an inconvenience for guest having to go down to LL. The pool area was dirty.

Reviewed on 13 Apr 2026

Holiday Inn Golden Gateway by IHG
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is £134 per night from 19 Apr to 20 Apr
£134
19 Apr - 20 Apr
includes taxes & fees
8.8/10 Excellent! (3,006 reviews)
Nice

Reviewed on 13 Apr 2026

Handlery Union Square Hotel
See all 4,870 properties in Mission Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Mission Bay travel package cost?
Say yes to new adventures with our Mission Bay travel packages, which start from a low £1,123. Choose the flights and hotels that match your travel style. Then, add on one or two tours or experiences for an unforgettable escape.
If I'm not able to travel, can I cancel my Mission Bay travel package?
It is possible to cancel your Mission Bay booking if your plans have been upended. Whether you'll incur a fee or not depends on your airline, hotel or car rental company. You may be able to cancel or change free of charge if you booked in the last 24 hours. Head to our Customer Service Portal for more information.
How do I get a cheap travel package to Mission Bay?
It's easy. Just bundle everything together. Flights, rental cars and hotels — combine whatever you need into a Mission Bay travel package to save loads of cash. Score even more discounts when you add extras such as experiences or tours to your booking. But that's not the only impressive part. You have the freedom to customize your holiday your way. We offer over 550 air carriers and 1,000,000 hotels across the world, so that everyone has a chance to travel and fulfil those holiday fantasies.
Does Expedia offer Book Now, Pay Later Mission Bay holidays?
Expedia has teamed up with online lender Klarna to make booking your next getaway easier on your bank balance. Paying by instalment means you can spread the costs of your dream holiday, leaving you with more cash to splash while you're away. Klarna has several payment plans to choose from, so you're sure to find one that suits your budget. Check out these flexible payment options:

  • Pay monthly holidays: Klarna has manageable monthly payment plans that work for all budget sizes, so you can have that well-earned holiday now.
  • Pay in instalments holidays: If you want to pay off your getaway in multiple transactions, holidays paid in instalments might be right for your Book Now, Pay Later holiday through Klarna.
  • Low deposit holidays: If paying a small percentage of your trip (rather than all of it upfront) makes it easier to hit that "book now" button, opt for a low deposit holiday payment plan with Klarna.

Where should I stay in Mission Bay?
Urban explorers come from every corner of the globe to experience Golden Gate Bridge and Pier 39 in Mission Bay. Book yourself a room near these top attractions and visit them at your leisure.
What are the top hotels in Mission Bay?
If this will be your first visit to Mission Bay, book a room at Hilton San Francisco Financial District or San Francisco Marriott Marquis. Both have good amenities and are popular options with many savvy travellers.
How far in advance should I book my Mission Bay holiday?
Search Expedia to compare international airfares ASAP. You can usually purchase a seat up to a year in advance. If you don't see your preferred carrier, or you've left things to the last moment, don't worry. Cheap tickets to Mission Bay sometimes emerge a few weeks before the date of departure.
What does an Expedia Mission Bay travel package include?
Expedia has all you need to book your Mission Bay trip, but what your package looks like is totally up to you. Pick from a combination of rental cars, flights and hotels. Searching for some tours or activities to keep you busy? Once you've made your booking, you can add them on too. Whatever your budget or style, there's a deal to match your needs.
What should I know before booking a Mission Bay travel package?
An Expedia travel package can be customized for your circumstances and is a simple way to make your money go further. What you include is your call. Rental cars, hotels and flights — come up with a combination that suits your plans.
Can I choose my airline with a Mission Bay Expedia travel package?
Yes, and with over 550 airlines to pick from throughout the world, you have loads of choice. Look through the available options and find out which airline best suits your budget and needs.

Popular places to visit

Chase Center San Francisco Skyline Aerial Photography

Chase Center

Catch an event at Chase Center during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its entertainment choices.

Chase Center

Things to do

California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

£37
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
San Francisco City Lights Cruise

California Sunset Cruise (2-hours)

£43
per adult
94% of travellers recommend
California Sunset Cruise (2-hours)
Go City: San Francisco All-Inclusive Pass with 25+ Attractions

Go City: San Francisco All-Inclusive Pass with 30+ Attractions

£82
per adult
88% of travellers recommend
Go City: San Francisco All-Inclusive Pass with 30+ Attractions
See all activities in San Francisco

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.