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Check prices for these dates

Tonight
12 Oct - 13 Oct
Tomorrow
13 Oct - 14 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

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Our top choices for Puxico hotels

A modern hotel lobby with a bar area, seating, and artwork on the walls.
A reception desk with a wooden panel design, a white vase with flowers, and a 'Hilton HONOR' sign.
A modern hotel with a prominent sign, a covered entrance, and a well-lit exterior.
A modern kitchen with a large island, bar stools, wine bottles, and a built-in TV.

1. Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
Dexter
United States
Bryan
£84
includes taxes & fees
25 Oct - 26 Oct
Hampton Inn By Hilton Dexter
A spacious lobby with a reception desk, seating area, and large windows.
A spacious conference room with brick walls, multiple tables and chairs, a large window, and a mounted TV.
A hotel room with a bed, a desk, a chair, a sofa, and a TV.
A spacious lobby with a high ceiling, a mezzanine level, and a seating area with a sofa and chairs.

2. Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
Poplar Bluff
United States
Dean
£80
includes taxes & fees
18 Oct - 19 Oct
Drury Inn & Suites Poplar Bluff
Exterior
Pool
Exterior
A modern dining area with wooden tables and chairs, a mounted television, and a coffee station with various drink options.

3. Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
Poplar Bluff
United States
Rhonda
£77
includes taxes & fees
1 Nov - 2 Nov
Hampton Inn Poplar Bluff
A diner with booth seating, a checkered floor, and a counter with a cash register.
A hotel room with a bed, a desk, a chair, a large mirror, a sink, and a trash bin.
A lobby with a round rug, two potted plants, three framed artworks, and two black leather chairs.
A gym with multiple exercise machines, a clock on the wall, and a window with blinds.

4. Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
Dexter
United States
Steven
£74
includes taxes & fees
1 Nov - 2 Nov
Travelodge by Wyndham Dexter
A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.
A kitchen with wooden cabinets, a stainless steel sink, a microwave, and a dishwasher.
A hotel reception area with a reception desk, framed certificates, and a painting on the wall.
A living room with a sofa, a coffee table, a clock, and a painting on the wall.

5. Econo Lodge Dexter

Econo Lodge Dexter
Dexter
£44
includes taxes & fees
10 Nov - 11 Nov
Econo Lodge Dexter
A coffee shop with a coffee machine, espresso cups, a sink, and a trash bin.
A hotel room with two beds, a desk with a lamp, a chair, a dresser, and a door with a handle.
A hotel hallway with patterned carpet, light green walls, and a ceiling with recessed lighting.
A kitchen with a white microwave, a fruit basket, a coffee maker, and a storage container.

6. Dexter Inn

Dexter Inn
Dexter
United States
Edward
£59
includes taxes & fees
13 Oct - 14 Oct
Dexter Inn
A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.
An outdoor patio with a table and chairs, a large umbrella, and a glass door leading to an interior space.
A corner market with a refrigerated display case and a pantry area.
A reception area with a wooden counter, a coffee machine, and a display of pastries.

7. Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
Poplar Bluff
United States
Nancy
£83
includes taxes & fees
9 Nov - 10 Nov
Fairfield Inn & Suites by Marriott Poplar Bluff
A hotel room with a sofa, a small table, a chair, a desk, two lamps, a window with curtains, and a framed picture on the wall.
A Holiday Inn hotel with a covered entrance, multiple flags, and a brick facade.
A hotel room with a desk, chair, and a small seating area. It includes a microwave, coffee maker, and a refrigerator.
A hotel room with two beds, a bedside lamp, a bench, a mirror, and a door leading to another room.

8. Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
Poplar Bluff
United States
Nathan
£72
includes taxes & fees
18 Oct - 19 Oct
Holiday Inn Poplar Bluff by IHG
A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.
A hotel reception area with a modern design, featuring a reception desk, a glass door, and a wall with framed pictures and a large number '6' sign.
A compact kitchen with a dark wooden desk, a black refrigerator, a microwave, and a coffee maker.
A motel with a prominent '66' sign, large windows, and a flat roof.

9. Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
Poplar Bluff
United States
Cindy
£60
includes taxes & fees
26 Oct - 27 Oct
Motel 6 Poplar Bluff, MO
A hotel lobby with a reception desk, a blue sofa, a fireplace, and a television.
A hotel lobby with a coffee station, seating area, and a television screen.
A hotel room with a bed, a sofa, a small table, and a painting on the wall.
A hotel room with a bed, two armchairs, a sofa, a small table, a TV, a ceiling fan, and a window with curtains.

10. Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North
Poplar Bluff
United States
Muhammad
£63
includes taxes & fees
1 Nov - 2 Nov
Comfort Inn Poplar Bluff North
A hotel room with two beds, a TV, a mirror, a wardrobe, and a desk.
A bathroom with a bathtub, toilet, and a shower curtain.
A window with a view of a parking lot and buildings, a welcome sign, and a credit card machine.
A row of single-story brick buildings with attached garages, likely a motel or small hotel, with a parking lot in front and a grassy area with a gazebo.

11. OYO Hickory House Inn

OYO Hickory House Inn
Dexter
United States
DIEGO
£51
includes taxes & fees
26 Oct - 27 Oct
OYO Hickory House Inn
A hotel room with a bed, two bedside lamps, a framed picture of a building, and a nightstand with a phone.
A two-story motel with a covered parking area and a bench outside.
A self-service breakfast area with a refrigerated drink cooler, a coffee machine, and various food items on the counter.
A lobby with a reception desk, a Coca-Cola vending machine, a snack vending machine, and a seating area with a round table.

12. Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri
Poplar Bluff
United States
Diana
£57
includes taxes & fees
20 Oct - 21 Oct
Super 8 by Wyndham Poplar Bluff Missouri
A living room with a blue wall, a fireplace, a sofa, and a chair.
A bar area with stools and a counter where a bartender is serving drinks.
A hotel room with two beds, a vanity with a mirror, a chair, and a dresser.
A sign for EC REED'S MERCANTILE & HOTEL with a geometric design.

13. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
Marble Hill
United States
Miranda
£86
includes taxes & fees
13 Oct - 14 Oct
EC Reed's Mercantile and Hotel
A rustic cabin with a metal roof, surrounded by a wooden deck and picnic tables, set in a forested area.
A bedroom with a wooden bed, a bench, and a window.
Front of property
A calm lake with a wooden dock and a forested island in the distance.

14. Lake Wappapello

Lake Wappapello
Williamsville
United States
Tonya
£72
includes taxes & fees
13 Oct - 14 Oct
Lake Wappapello
A spacious living area with a dark grey sofa set, a matching ottoman, and a wooden-paneled wall.
A house with a red door, a porch with rocking chairs, and a wreath on the door.
A two-story house with a deck and a covered porch.
A spacious dining area with a stone wall, wooden furniture, and a fireplace.

15. 40-acre Poplar Bluff Nature Lovers Paradise!

40-acre Poplar Bluff Nature Lovers Paradise!
Poplar Bluff
United States
Anonymous traveller
£224
includes taxes & fees
21 Oct - 22 Oct
40-acre Poplar Bluff Nature Lovers Paradise!
View all properties

Hotels recommended for families in Puxico

A modern hotel lobby with a bar area, seating, and artwork on the walls.
A reception desk with a wooden panel design, a white vase with flowers, and a 'Hilton HONOR' sign.
A modern hotel with a prominent sign, a covered entrance, and a well-lit exterior.
A modern kitchen with a large island, bar stools, wine bottles, and a built-in TV.

Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
Dexter
£84
includes taxes & fees
25 Oct - 26 Oct
Hampton Inn By Hilton Dexter
A coffee shop with a coffee machine, espresso cups, a sink, and a trash bin.
A hotel room with two beds, a desk with a lamp, a chair, a dresser, and a door with a handle.
A hotel hallway with patterned carpet, light green walls, and a ceiling with recessed lighting.
A kitchen with a white microwave, a fruit basket, a coffee maker, and a storage container.

Dexter Inn

Dexter Inn
Dexter
£59
includes taxes & fees
13 Oct - 14 Oct
Dexter Inn
A spacious lobby with a reception desk, seating area, and large windows.
A spacious conference room with brick walls, multiple tables and chairs, a large window, and a mounted TV.
A hotel room with a bed, a desk, a chair, a sofa, and a TV.
A spacious lobby with a high ceiling, a mezzanine level, and a seating area with a sofa and chairs.

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
Poplar Bluff
£80
includes taxes & fees
18 Oct - 19 Oct
Drury Inn & Suites Poplar Bluff
Exterior
Pool
Exterior
A modern dining area with wooden tables and chairs, a mounted television, and a coffee station with various drink options.

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
Poplar Bluff
£77
includes taxes & fees
1 Nov - 2 Nov
Hampton Inn Poplar Bluff
A diner with booth seating, a checkered floor, and a counter with a cash register.
A hotel room with a bed, a desk, a chair, a large mirror, a sink, and a trash bin.
A lobby with a round rug, two potted plants, three framed artworks, and two black leather chairs.
A gym with multiple exercise machines, a clock on the wall, and a window with blinds.

Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
Dexter
£74
includes taxes & fees
1 Nov - 2 Nov
Travelodge by Wyndham Dexter
A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.
An outdoor patio with a table and chairs, a large umbrella, and a glass door leading to an interior space.
A corner market with a refrigerated display case and a pantry area.
A reception area with a wooden counter, a coffee machine, and a display of pastries.

Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
Poplar Bluff
£83
includes taxes & fees
9 Nov - 10 Nov
Fairfield Inn & Suites by Marriott Poplar Bluff
A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.
A hotel reception area with a modern design, featuring a reception desk, a glass door, and a wall with framed pictures and a large number '6' sign.
A compact kitchen with a dark wooden desk, a black refrigerator, a microwave, and a coffee maker.
A motel with a prominent '66' sign, large windows, and a flat roof.

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
Poplar Bluff
£60
includes taxes & fees
26 Oct - 27 Oct
Motel 6 Poplar Bluff, MO
A hotel room with a sofa, a small table, a chair, a desk, two lamps, a window with curtains, and a framed picture on the wall.
A Holiday Inn hotel with a covered entrance, multiple flags, and a brick facade.
A hotel room with a desk, chair, and a small seating area. It includes a microwave, coffee maker, and a refrigerator.
A hotel room with two beds, a bedside lamp, a bench, a mirror, and a door leading to another room.

Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
Poplar Bluff
£72
includes taxes & fees
18 Oct - 19 Oct
Holiday Inn Poplar Bluff by IHG
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Learn more about Puxico

Head to sights like Mark Twain National Forest and Mingo Wilderness as you discover Puxico.

See all hotels in Puxico
A night scene with a clear sky, a crescent moon, and two silhouetted trees against a twilight sky.
Photo by Mike McClain

Top Puxico Hotel Reviews

Frequently asked questions

When is the best time to go to Puxico?
The best time to visit Puxico, Missouri, is during the spring (late April to early June) and autumn (September to October) months.These periods offer pleasant weather, with comfortable temperatures and generally less humidity, making it ideal for outdoor activities and exploring the local area. Spring brings blooming dogwoods and redbuds, while autumn showcases beautiful fall foliage, particularly in the surrounding Mingo National Wildlife Refuge.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Puxico.
How much is the nightly rate at a Puxico hotel?
Prices for hotels in Puxico often vary, but you can find a great deal on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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