Panama City Holidays from £645

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Your Panama City Holiday

The tropical climate, cosmopolitan vibe and rich history are three of the many reasons why people love this coastal city. Discover this incredible destination as you please with a Panama City holiday package. Miraflores Locks, Bridge of the Americas and Metropolitan Cathedral of Panama are just a few of the sights worth exploring during your trip to Panama City. A few quick clicks is all it takes to put together your dream Panama City holiday on Expedia.

Top Panama City Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Arcadia Condo Suites

Arcadia Condo Suites

2.5 out of 5
Costa del Este
per person
14 Aug - 17 Aug
found 1 day ago
Return direct flight included
Kingston (KIN) to Panama City (PTY)
9/10 Wonderful! (22 reviews)
I only stay for a night but if I ever returned to Panama, it would be here.

Reviewed on 4 Jul 2025

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
per person
14 Aug - 17 Aug
found 1 day ago
Return direct flight included
Kingston (KIN) to Panama City (PTY)
9/10 Wonderful! (925 reviews)
Property was in a great location and the the breakfast was really good.

Reviewed on 29 Jun 2025

Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
Bella Vista
per person
14 Aug - 17 Aug
found 1 day ago
Return direct flight included
Kingston (KIN) to Panama City (PTY)
9/10 Wonderful! (1,002 reviews)
Nice property mediocre service. We arrived at check in and room was not ready at 4 pm. All things there take forever…. Slow service!

Reviewed on 6 Jun 2025

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
per person
14 Aug - 17 Aug
found 1 day ago
Return direct flight included
Kingston (KIN) to Panama City (PTY)
8.4/10 Very Good! (928 reviews)
The hotel is beautiful and our suite was very spacious. Felt like home away from home.

Reviewed on 3 Jul 2025

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
San Francisco
per person
14 Aug - 17 Aug
found 1 day ago
Return direct flight included
Kingston (KIN) to Panama City (PTY)
8.8/10 Excellent! (1,005 reviews)
Good hotel for the price that I paid

Reviewed on 30 Jun 2025

Where to stay in Panama City

Find the best Panama City areas and neighborhoods for the activities you enjoy most. Learn more about Panama City
Default Image

Casco Viejo

3.5/5(3 area reviews)

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.

Find hotels in Casco Viejo

Panama City Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)
Max Temp Winter
29ºC
Max Temp Summer
29ºC
Top Sights
Metropolitan Cathedral of Panama, Soberania National Park and Frank Gehry Biodiversity Museum

Top hotels in Panama City

Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
The price is £104 per night from 20 Jul to 21 Jul
£104
20 Jul - 21 Jul
includes taxes & fees
9/10 Wonderful! (4,056 reviews)
"excelente desayuno"

Reviewed on 3 Jul 2025

Hotel Riu Plaza Panama
Waymore Hotel Spa & Casino
Waymore Hotel Spa & Casino
4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
Fully refundableReserve now, pay when you stay
The price is £65 per night from 7 Jul to 8 Jul
£65
7 Jul - 8 Jul
includes taxes & fees
9/10 Wonderful! (321 reviews)
"There was a casino in it to enjoy. The bar areas were nice. The pool was nice, the rooms were clean and updated. It was on a side street with several stores/restaurants to choose from. The staff were very friendly and accommodating."

Reviewed on 3 Jul 2025

Waymore Hotel Spa & Casino
Sheraton Grand Panama
Sheraton Grand Panama
4 out of 5
Via Israel And 77th Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is £88 per night from 18 Jul to 19 Jul
£88
18 Jul - 19 Jul
includes taxes & fees
8.4/10 Very Good! (887 reviews)
"I attended an event and thia was well staffed. Beautiful place!"

Reviewed on 30 Jun 2025

Sheraton Grand Panama
See all 1,276 properties in Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Holidays

All Inclusive Holidays

Beach Holidays

Beach Holidays

Family Friendly Holidays

Family Friendly Holidays

Popular places to visit

Cinta Costera

Cinta Costera

4/5(5 reviews)

Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Cinta Costera
Fuerte Amador Resort & Marina

Fuerte Amador Resort & Marina

Explore the waterfront in Ancon with a trip to Fuerte Amador Resort & Marina. Visit the shops and top-notch restaurants in this vibrant area.

Fuerte Amador Resort & Marina
Metropolitan Cathedral of Panama

Metropolitan Cathedral of Panama

4/5(5 reviews)

Learn about the local history of Panama City with a stop at Metropolitan Cathedral of Panama. Visit the shops and top-notch restaurants in this vibrant area.

Metropolitan Cathedral of Panama

What to do in Panama City

Slingshot Tour Panama

Slingshot Tour Panama

£86
per adult
Slingshot Tour Panama
Day Tour

Day Tour in San Blas Islands All Included Visiting 4 Islands

£110
per adult
94% of travellers recommend
Day Tour in San Blas Islands All Included Visiting 4 Islands
Panama City: Poin Glass Observation Deck Ticket with VR Tour

Panama City: Poin Glass Observation Deck Ticket with VR Tour

£24
per adult
100% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
See all activities in Panama City

Frequently asked questions

Why should I book my Panama City holiday with Expedia?
With excellent-value flights, accommodation and car hire choices all in the same place, Expedia makes planning your Panama City holiday a cinch. Plus, we can help you bundle your bookings into a package holiday so you can get even more savings. Select from wonderful properties, add your flights and/or a car hire (and maybe also some fun tours!) and land unbeatable prices. Had a change of plans? Expedia has a flexible cancellation policy for many reservations. To find out more, make your way to our Customer Service Portal link.
When is the best time of year to holiday in Panama City?
Peak season falls in February, March and May and is a thrilling time to visit --- if you don't mind the crowds. January, July and December are typically quieter times of the year. With average daytime temperatures of 25ºC, November is the coolest period in Panama City. The warmest month is January, when you can expect averages of 26ºC throughout the day. Whatever the weather conditions, you'll discover loads to keep you occupied here.
What are the top hotels for my holiday in Panama City?
Aloft Panama and Hotel Riu Plaza Panama are among the best picks in the Casco Viejo neighbourhood. If you want to stay in the San Felipe area, reserve a room at Exe Oriental Panama or Manrey Boutique Hotel.
How do I get a cheap holiday to Panama City?
Lock in flights that suit your busy schedule, add a hotel to your booking and see how much you save with a Panama City holiday. It's that simple! From flights and hotels to tours and hire cars, Expedia makes travelling on a budget easy. And with more than 400 partner airlines and 321,000 hotels throughout the world to select from, you won't be short of choice. Learn more about how you can save money on your next holiday when you combine your hotel and flight bookings with Expedia.
What should I do on my Panama City holiday?
There are plenty of things to see and do while on your holiday in Panama City. Miraflores Locks, Metropolitan Cathedral of Panama, Albrook Shopping Mall and Multiplaza Pacific Mall are among this destination's major attractions.
What is the best neighbourhood to stay in when on holiday in Panama City?
If it's your first visit to Panama City, stay in Casco Viejo. This neighbourhood is where you'll find some amazing attractions, like Metropolitan Cathedral of Panama.
Do I need a visa for my Panama City holiday?
Official government websites are the best source of information on visa requirements, application procedures and any supporting documentation. Your nationality and the reason for your visit, whether it be for tourism or work, will determine if you'll need a visa for Panama City. Also ensure your passport is up to date and has a minimum of six months validity remaining beyond your return date. Do all your travel planning well ahead of time to avoid any nasty last-minute surprises.
What should I wear on my Panama City holiday?
Do some research into the sorts of things people in Panama City wear, and maybe even browse style blogs for some fashion tips. Whatever your look, aim to create a versatile wardrobe filled with pieces that work for your destination and show off your personal style. Daytime temperatures during November, Panama City's coolest month, are around 25ºC. January marks this destination's warmest month when the average daily temperature reaches 26ºC. Our top piece of advice? Take the guesswork out of what to pack and check the weather forecast.
What does an Expedia Panama City holiday include?
With Expedia, you can choose a combination of car hires, hotels and flights to create your perfect Panama City package. Once you've made your booking, simply add on all the fun stuff like tours and experiences. Remember, the more you bundle, the more you stand to save! Expedia features many properties, with the most popular in Panama City being apartments and hotels. With Expedia, you'll always have the freedom and flexibility to personalise your holiday however you like.
Does Expedia offer Book Now, Pay Later Panama City holidays?
Expedia has partnered with online lender Klarna to make booking your next getaway easier on the purse strings. Paying in instalments means you can spread the costs of your next dream escape, leaving you with more money to spend while you're away. Klarna has several payment plans to pick from, so you're sure to find something that fits your budget. Browse these flexible payment options:

  • Pay monthly holidays: Realise your holiday dreams sooner with Klarna's easy instalment plans. If paying just a small amount each month works for you, pick this option during the checkout process.
  • No-deposit holidays: When you spot an awesome deal but don't have the full amount yet, Klarna's no-deposit holiday plan will allow you to Book Now, Pay Later to lock in your escape.

Can I choose my airline with a Panama City Expedia holiday?
Most definitely. We have access to over 400 partner airlines throughout the world, so you can customise your Panama City holiday according to your needs and budget.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.