A large eye sculpture in a park surrounded by trees.

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Check availability on Northeast Missouri Luxury Hotels

Tonight
6 Oct - 7 Oct
Tomorrow
7 Oct - 8 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for Northeast Missouri luxury hotels

An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A grand lobby with a central chandelier, multiple levels, and rows of liquor bottles.
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.
A bakery display case with various pastries and cakes.

1. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Indulge in lavish comfort at this St. Charles retreat featuring a full-service spa, seasonal pool, and 6 exceptional restaurants.
£162
includes taxes & fees
12 Oct - 13 Oct
Ameristar Casino Resort and Spa
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.
A grand lobby with a central seating area, a staircase, and a decorative ceiling.
An outdoor patio with a brick fireplace, wicker furniture, and a dining table set with food and drinks.
A restaurant with multiple dining tables and chairs, a bar area with shelves of bottles, and a large mirror above the bar.

2. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
Central West End
  • Indulge in historic elegance at this St. Louis gem featuring 3 restaurants, a spectacular pool area, and luxurious rooms near Forest Park.
£166
includes taxes & fees
1 Nov - 2 Nov
The Royal Sonesta Chase Park Plaza St. Louis
A bar area with wooden tables, leather seating, and a bar counter.
A bar area with a wooden counter, hanging glasses, and a liquor display.
A hotel room with a bed, bedside table, lamp, chair, desk, microwave, refrigerator, and a door.
A large white building with a central tower, a parking lot, and a tree with red leaves.

3. The Inn at Elijah McLeans

The Inn at Elijah McLeans
Washington
£116
includes taxes & fees
12 Oct - 13 Oct
The Inn at Elijah McLeans
A cozy lounge area with leather sofas, a fireplace, and a bar counter.
A modern building with a unique, curved roof structure.
A traditional building with a stone facade, large windows, and outdoor seating area with wicker furniture.
An outdoor patio area with a pool, red umbrellas, and seating arrangements.

4. The Cheshire

The Cheshire
Richmond Heights
£133
includes taxes & fees
25 Oct - 26 Oct
The Cheshire
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."
A reception desk with a wooden finish and the name "IDOL WOLF" on it.

5. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Indulge in artistic luxury at this city centre St. Louis hotel with spa services and indoor pool.
£131
includes taxes & fees
1 Nov - 2 Nov
21C Museum Hotel St Louis
A spacious lobby with a brown leather sofa, multiple chairs, a coffee table with a skull decoration, and a large chandelier.
A hotel room with orange furniture, a glass coffee table, a dining area with a table and chairs, and a patterned carpet.
A large, multi-story hotel with the name "Doubletree by Hilton" prominently displayed on the facade.
A hotel room with a large bed, a desk with a chair, a television, a mirror, and a wardrobe.

6. DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield
Chesterfield
  • Chesterfield hotel offers plush comforts with indoor tennis courts, dual pools, and premium bedding.
£122
includes taxes & fees
30 Oct - 31 Oct
DoubleTree by Hilton Hotel St. Louis - Chesterfield
A restaurant with round tables and chairs, a bar area, and a patterned ceiling.
A spa bath with a sign indicating a capacity of 8 persons.
A Drury Plaza Hotel with a large parking lot and multiple cars parked in front.
A lobby with a reception desk, seating area with sofas and ottomans, and a patterned rug.

7. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
Brentwood
£119
includes taxes & fees
1 Nov - 2 Nov
Drury Plaza Hotel St. Louis Brentwood
A modern living room with a pool view, large windows, and a dining area.
A bed with a tray of food and drinks, a bottle, and glasses on a woven mat.
A Club Boulders sign with a logo, located at the entrance of a building with a wooden facade and a window reflecting interior lights.
A book titled 'Missouri' on a small round table, a golf ball, and a coaster with a letter 'B'.

8. Club Boulders by Pinemark® Heated Pool+Hot Tub

Club Boulders by Pinemark® Heated Pool+Hot Tub
Bourbon
£481
includes taxes & fees
7 Oct - 8 Oct
Club Boulders by Pinemark® Heated Pool+Hot Tub
A compact living space with a sofa, a TV, a kitchen area with a fridge, microwave, and coffee maker, and a dining table.
A living room with a sofa, armchair, and coffee table. There is a staircase with a railing and a door in the background.
A black building with large windows, a covered porch with a flag, and potted plants.
A modern kitchen with a wooden island, bar stools, and a flat-screen TV.

9. The Mercantile on the Katy Trail

The Mercantile on the Katy Trail
Hermann
  • Newly renovated Victorian retreat offers golf, garden sanctuary, and luxury suites on the Katy Trail.
£158
includes taxes & fees
27 Oct - 28 Oct
The Mercantile on the Katy Trail
A modern hotel lobby with a glass facade, seating area, and a staircase.
A couple relaxing by a window overlooking a bridge and water.
A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.
A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.

10. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Lavish riverside luxury awaits at the Four Seasons St. Louis with spa indulgences and poolside bliss.
£331
includes taxes & fees
25 Oct - 26 Oct
Four Seasons Hotel St Louis
View all properties

Top Northeast Missouri Hotel Reviews

Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"Fantastic stay at the Drury Inn St. Louis at Union Station. The location is excellent, especially if you’re in town for an event downtown. The hotel was clean, comfortable, and incredibly convenient, and the staff was friendly and welcoming from check-in to checkout. One of the biggest standouts with Drury is the value. Between the complimentary breakfast, evening food and drinks, and the overall quality of the stay, you really feel like you’re getting more than what you paid for. The room was comfortable, everything was well maintained, and the hotel had a great atmosphere. Being right by Union Station and close to the major downtown attractions made getting around St. Louis incredibly easy. I’ve stayed in plenty of hotels while traveling, and this was easily one of the better experiences. I would absolutely stay here again and would recommend it to anyone visiting St. Louis. Five stars all the way."
Brandon 1-night trip
Posted 1 hour ago
Drury Plaza Hotel St. Louis Union Station
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

10/10 Excellent
"I enjoyed the atmosphere from the moment I arrived. The young man who checked me in was professional but friendly and welcoming—- like I mattered. It’s rare and was felt."
Michele 1-night trip
Posted 1 hour ago
Pear Tree Inn St. Louis Airport
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

10/10 Excellent
"Nice place"
JENNIFER 2-night trip
Posted 8 hours ago
Clayton Plaza Hotel & Extended Stay
Moonrise Hotel

Moonrise Hotel

10/10 Excellent
"Great family trip great business trip whatever the occasion is it’s amazing"
Denise 1-night trip
Posted 18 hours ago
Moonrise Hotel
Forest Park Hotel by MDR

Forest Park Hotel by MDR

10/10 Excellent
"The rooms were spacious and beds so comfortable."
Kevan 3-night trip
Posted 23 hours ago
Forest Park Hotel by MDR
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

10/10 Excellent
"Great stay and rooms were very clean,amenities provided was a plus"
Ronnie 1-night trip
Posted 1 day ago
Hollywood Casino & Hotel St. Louis

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