Find luxury hotels in Northeast Missouri, MO
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Northeast Missouri Luxury Hotels
Our top choices for Northeast Missouri luxury hotels
9.2 out of 10, Wonderful, (567 reviews)
- Ritz-Carlton elegance defines this St. Louis retreat with indulgent spa services and dining excellence.
"Top quality
Concierge floor worth the cost"
Norma E.
The price is £431
includes taxes & fees
24 May - 25 May
9.4 out of 10, Exceptional, (113 reviews)
"Really fine accommodations.
Outstanding view.
Luxury amenities.
"
Joseph
The price is £281
includes taxes & fees
4 Jun - 5 Jun
8.6 out of 10, Excellent, (1,002 reviews)
- Indulge in lavish comfort at this St. Charles retreat featuring a full-service spa, seasonal pool, and 6 exceptional restaurants.
"Room was nice."
MELISSA
The price is £163
includes taxes & fees
4 Jun - 5 Jun
9.0 out of 10, Wonderful, (1,934 reviews)
- Boutique retreat blends urban charm with luxury, from rooftop views to Egyptian cotton and rainfall showers.
"We felt luxurious in our room"
Darian
The price is £122
includes taxes & fees
31 May - 1 Jun
9.6 out of 10, Exceptional, (1,016 reviews)
"Clean and comfortable beds. The amenities were amazing. Loved our stay! "
Merissa
The price is £118
includes taxes & fees
1 Jun - 2 Jun
7.8 out of 10, Good, (942 reviews)
"Overall good condition hotel, and the beds were very comfortable. Excellent proximity to the airport (5 min hotel shuttle ride), and car rental facilities which enabled us to return our vehicle early."
Steven
The price is £110
includes taxes & fees
18 May - 19 May
8.0 out of 10, Very good, (1,000 reviews)
"Hotel is nice - clean & comfortable. Service in bar & restaurant were wonderful."
Anonymous traveller
The price is £134
includes taxes & fees
22 May - 23 May
St. Louis Union Station Hotel, Curio Collection by Hilton
St. Louis Union Station Hotel, Curio Collection by HiltonDowntown West
8.6 out of 10, Excellent, (1,007 reviews)
- Experience grandeur in a historic hotel with 7 restaurants, seasonal pool, and concierge services in city centre St. Louis.
"The hotel was absolutely gorgeous! It had the best vibe going on. We ate at the onsite restaurants, where the food was amazing. Took some awesome pictures at different locations in the hotel and enjoyed the luxury of it all. "
Samantha
The price is £137
includes taxes & fees
27 May - 28 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Northeast Missouri Hotel Reviews
The Wildwood Hotel
10/10 Excellent
Explore a world of travel with Expedia
- Gay-Friendly Hotels in Boonville
- Cairo Hotels
- Callao Hotels
- Canton Hotels
- Adults Only Resorts & in Columbia
- Cheap Hotels in Columbia
- Hotels with Indoor Pools in Columbia
- Spa Hotels in Columbia
- All-Inclusive Hotels in Missouri
- Beach Resorts & in Missouri
- Boutique Hotels in Missouri
- Cheap Hotels in Missouri
- Casino Hotels in Missouri
- Family-Friendly Hotels in Missouri
- Golf Hotels in Missouri
- Hotels Suites in Missouri
- Hotels with a Bar in Missouri
- Hotels with Breakfast in Missouri
- Hotels with Connecting Rooms in Missouri
- Hotels with Gym in Missouri
- Hotels with Restaurant in Missouri
- Hotels with Room Service in Missouri
- Hotels with smoking rooms in Missouri
- Lakeside Hotels in Missouri
- Luxury Hotels in Missouri
- Ski Hotels in Missouri
- Spa Hotels in Missouri
- Edina Hotels
- Ethel Hotels
- Gibbs Hotels
- Gay-Friendly Hotels in Hannibal
- Hotels with Indoor Pools in Hannibal
- Adults Only Resorts & in Hermann
- Gay-Friendly Hotels in Hermann
- Hotels with Hot Tubs in Hermann
- Holliday Hotels
- Hunnewell Hotels
- Hurdland Hotels
- Gay-Friendly Hotels in Kingdom City
- Gay-Friendly Hotels in Kirksville
- Kirksville Hotels
- La Grange Hotels
- La Plata Hotels
- Hotels near La Plata Station
- Lentner Hotels
- Lewistown Hotels
- Macon Hotels
- Hotels near Mark Twain State Park
- Memphis Hotels
- Gay-Friendly Hotels in Mexico
- Monroe City Hotels
- New Cambria Hotels
- Pet-Friendly Hotels in New Florence
- Palmyra Hotels
- Paris Hotels
- Pet-Friendly Hotels in Rutledge
- Rutledge Hotels
- Shelbina Hotels
- Shelbyville Hotels
- Stoutsville Hotels
- Taylor Hotels
- Luxury Hotels in Troy
- West Quincy Hotels
- Flights to Gibbs
- Flights to Holliday
- Flights to Kirksville
- Flights to Macon
- Flights from Ethel
- Flights from Kirksville
- Flights from Palmyra
- Flights from Hunnewell
- Flights from Gibbs
- Flights from Goss
- Flights from Baring
- Flights from Lewis County
- Flights from Scotland County
- Flights from Monroe County
- Flights from Adair County
- Flights from La Plata
- Flights from Macon
- Flights from Maywood
- Flights from Allentown (ABE) to Kirksville (IRK)
- Flights from Champaign (CMI) to Kirksville (IRK)
- Flights from Dubuque (DBQ) to Kirksville (IRK)
- Flights from Lazaro Cardenas (LZC) to Kirksville (IRK)
- Flights from Manchester (MAN) to Kirksville (IRK)
- Flights from Chicago (ORD) to Kirksville (IRK)
- Flights from St. Louis (STL) to Kirksville (IRK)
- Flights from Boulder (WBU) to Kirksville (IRK)